Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases

Chemistry and Biology

Volumn 17, Issue 10, 2010, Pages 1084-1091

  Gollapalli, Deviprasad R ^a   MacPherson, Iain S ^a   Liechti, George ^b   Gorla, Suresh Kumar ^a   Goldberg, Joanna B ^b   Hedstrom, Lizbeth ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; INOSINATE DEHYDROGENASE; RECOMBINANT PROTEIN;

ARTICLE; BINDING SITE; BORRELIA BURGDORFERI; CHEMISTRY; CLASSIFICATION; COMPUTER SIMULATION; CRYPTOSPORIDIUM PARVUM; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; HELICOBACTER PYLORI; HUMAN; KINETICS; METABOLISM; STREPTOCOCCUS PYOGENES;

BINDING SITES; BORRELIA BURGDORFERI; COMPUTER SIMULATION; CRYPTOSPORIDIUM PARVUM; ENZYME INHIBITORS; HELICOBACTER PYLORI; HUMANS; IMP DEHYDROGENASE; KINETICS; RECOMBINANT PROTEINS; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); BORRELIA BURGDORFERI; CRYPTOSPORIDIUM PARVUM; ESCHERICHIA COLI; HELICOBACTER PYLORI; PROKARYOTA; PROTOZOA; STREPTOCOCCUS PYOGENES;

EID: 78049383245     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.07.014     Document Type: Article

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