Inhibition of IMPDH by mycophenolic acid: Dissection of forward and reverse pathways using capillary electrophoresis

Biochemistry

Volumn 35, Issue 22, 1996, Pages 6990-6997

  Fleming, Mark A ^a   Chambers, Stephen P ^a   Connelly, Patrick R ^a,b   Nimmesgern, Elmar ^a   Fox, Ted ^a   Bruzzese, Frank J ^a   Hoe, Stephen T ^a   Fulghum, John R ^a   Livingston, David J ^a   Stuver, Cameron M ^a   Sintchak, Michael D ^a   Wilson, Keith P ^a   Thomson, John A ^a  

^a VERTEX PHARMACEUTICALS   (United States)

^b Groton School   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYCOPHENOLIC ACID;

ARTICLE; BINDING SITE; CAPILLARY ELECTROPHORESIS; CATALYSIS; ENZYME BINDING; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME RELEASE; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; RECEPTOR OCCUPANCY;

ANIMALS; BASE SEQUENCE; CRICETINAE; CRYSTALLIZATION; DNA PRIMERS; ELECTROPHORESIS, CAPILLARY; ENZYME INHIBITORS; ESCHERICHIA COLI; IMP DEHYDROGENASE; INOSINE MONOPHOSPHATE; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MYCOPHENOLIC ACID; NAD; PROTEIN BINDING; RECOMBINANT PROTEINS;

CRICETINAE; ESCHERICHIA COLI;

EID: 15844389292     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9607416     Document Type: Article

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