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Volumn 46, Issue 9, 2012, Pages 1140-1149

Polyphenols decreased liver NADPH oxidase activity, increased muscle mitochondrial biogenesis and decreased gastrocnemius age-dependent autophagy in aged rats

Author keywords

Aging; Antioxidant status; Atrophy; Mitochondria; Xanthine oxidase

Indexed keywords

ANTIOXIDANT; CATALASE; CITRATE SYNTHASE; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; OXYGEN; RED GRAPE POLYPHENOL EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

EID: 84864648344     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2012.694428     Document Type: Article
Times cited : (28)

References (66)
  • 1
    • 0014340640 scopus 로고
    • Free radical theory of aging: Eff ect of free radical reaction inhibitors on the mortality rate of male LAF mice
    • Harman D. Free radical theory of aging: eff ect of free radical reaction inhibitors on the mortality rate of male LAF mice. J Gerontol 1968;23:476-482.
    • (1968) J Gerontol , vol.23 , pp. 476-482
    • Harman, D.1
  • 2
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science 1996;273:59-63. (Pubitemid 26255420)
    • (1996) Science , vol.273 , Issue.5271 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 3
  • 4
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • DOI 10.1113/jphysiol.2003.049478
    • Turrens JF. Mitochondrial formation of reactive oxygen spe- cies. J Physiol 2003;552:335-344. (Pubitemid 37321833)
    • (2003) Journal of Physiology , vol.552 , Issue.2 , pp. 335-344
    • Turrens, J.F.1
  • 6
    • 34347257042 scopus 로고    scopus 로고
    • Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
    • DOI 10.1016/j.freeradbiomed.2007.03.027, PII S0891584907002225
    • Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med 2007; 43:332-347. (Pubitemid 46992767)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.3 , pp. 332-347
    • Lambeth, J.D.1
  • 7
    • 79957969884 scopus 로고    scopus 로고
    • Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice
    • Ryan MJ, Jackson JR, Hao Y, Leonard SS, Alway SE. Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice. Free Radic Biol Med 2011;51:38-52.
    • (2011) Free Radic Biol Med , vol.51 , pp. 38-52
    • Ryan, M.J.1    Jackson, J.R.2    Hao, Y.3    Leonard, S.S.4    Alway, S.E.5
  • 8
    • 55449128351 scopus 로고    scopus 로고
    • Cytochrome P-450 2C9 signaling does not contrib- ute to age-associated vascular endothelial dysfunction in humans
    • Donato AJ, Eskurza I, Jablonski KL, Gano LB, Pierce GL, Seals DR. Cytochrome P-450 2C9 signaling does not contrib- ute to age-associated vascular endothelial dysfunction in humans. J Appl Physiol 2008;105:1359-1363.
    • (2008) J Appl Physiol , vol.105 , pp. 1359-1363
    • Donato, A.J.1    Eskurza, I.2    Jablonski, K.L.3    Gano, L.B.4    Pierce, G.L.5    Seals, D.R.6
  • 9
    • 85043330816 scopus 로고    scopus 로고
    • Oxidative stress in aging: Theoretical out- comes and clinical evidences in humans
    • Epub ahead of print
    • Gil Del Valle L. Oxidative stress in aging: Theoretical out- comes and clinical evidences in humans. Biomed Pharmaco- ther Sep 25 Epub ahead of print.
    • Biomed Pharmaco- Ther Sep , vol.25
    • Gil Del Valle, L.1
  • 10
    • 75149165994 scopus 로고    scopus 로고
    • Update on the oxida- tive stress theory of aging: Does oxidative stress play a role in aging or healthy aging?
    • Salmon AB, Richardson A, Perez VI. Update on the oxida- tive stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radic Biol Med 2010;48: 642-655.
    • (2010) Free Radic Biol Med , vol.48 , pp. 642-655
    • Salmon, A.B.1    Richardson, A.2    Perez, V.I.3
  • 12
    • 79952342349 scopus 로고    scopus 로고
    • Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain
    • Unno K, Sugiura M, Ogawa K, Takabayashi F, Toda M, Sakuma M, et al. Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain. Biol Pharm Bull 2010;34:311-317.
    • (2010) Biol Pharm Bull , vol.34 , pp. 311-317
    • Unno, K.1    Sugiura, M.2    Ogawa, K.3    Takabayashi, F.4    Toda, M.5    Sakuma, M.6
  • 13
    • 70349396998 scopus 로고    scopus 로고
    • Eff ect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats
    • Mahesh R, Bhuvana S, Begum VM. Eff ect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats. Cell Biochem Funct 2009;27:358-363.
    • (2009) Cell Biochem Funct , vol.27 , pp. 358-363
    • Mahesh, R.1    Bhuvana, S.2    Begum, V.M.3
  • 14
    • 78651377497 scopus 로고    scopus 로고
    • Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: Role of NADPH oxidase
    • Dal-Ros S, Zoll J, Lang AL, Auger C, Keller N, Bronner C et al. Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase. Biochem Biophys Res Commun 2011;404:743-749.
    • (2011) Biochem Biophys Res Commun , vol.404 , pp. 743-749
    • Dal-Ros, S.1    Zoll, J.2    Lang, A.L.3    Auger, C.4    Keller, N.5    Bronner, C.6
  • 15
    • 78649851597 scopus 로고    scopus 로고
    • Mediation of endog-enous antioxidant enzymes and apoptotic signaling by resvera-trol following muscle disuse in the gastrocnemius muscles of young and old rats
    • Jackson JR, Ryan MJ, Hao Y, Alway SE. Mediation of endog-enous antioxidant enzymes and apoptotic signaling by resvera-trol following muscle disuse in the gastrocnemius muscles of young and old rats. Am J Physiol Regul Integr Comp Physiol 2010;299:R1572-R1581.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Jackson, J.R.1    Ryan, M.J.2    Hao, Y.3    Alway, S.E.4
  • 18
    • 77957803185 scopus 로고    scopus 로고
    • Antioxidant supplementation had posi-tive eff ects in old rat muscle, but through better oxidative sta-tus in other organs
    • Mosoni L, Balage M, Vazeille E, Combaret L, Morand C Zagol-Ikapitte I, et al. Antioxidant supplementation had posi-tive eff ects in old rat muscle, but through better oxidative sta-tus in other organs. Nutrition 2010;26:1157-1162.
    • (2010) Nutrition , vol.26 , pp. 1157-1162
    • Mosoni, L.1    Balage, M.2    Vazeille, E.3    Combaret, L.4    Morand, C.5    Zagol-Ikapitte, I.6
  • 19
    • 75049085555 scopus 로고    scopus 로고
    • Skeletal Muscle Autophagy and Apoptosis during Aging: Eff Ects of Calorie Restriction and Life-long Exercise
    • Wohlgemuth SE, Seo AY Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: eff ects of calorie restriction and life-long exercise. Exp Geron-tol2010;45:138-148.
    • (2010) Exp Geron-tol , vol.45 , pp. 138-148
    • Wohlgemuth, S.E.1    Seo, A.Y.2    Marzetti, E.3    Lees, H.A.4    Leeuwenburgh, C.5
  • 21
    • 33748526240 scopus 로고    scopus 로고
    • Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle
    • DOI 10.1016/j.mad.2006.07.005, PII S0047637406001709
    • Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I, Derijard B. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle. Mech Ageing Dev 2006;127:794-801. (Pubitemid 44374662)
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.10 , pp. 794-801
    • Clavel, S.1    Coldefy, A.-S.2    Kurkdjian, E.3    Salles, J.4    Margaritis, I.5    Derijard, B.6
  • 22
    • 34848920863 scopus 로고    scopus 로고
    • ROS, mitochondria and the regu-lation of autophagy
    • Scherz-Shouval R, Elazar Z. ROS, mitochondria and the regu-lation of autophagy. Trends Cell Biol 2007;17:422-427.
    • (2007) Trends Cell Biol , vol.17 , pp. 422-427
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 23
    • 79954554400 scopus 로고    scopus 로고
    • Oxidative stress and skeletal muscle dys-function with aging
    • Aoi W, Sakuma K. Oxidative stress and skeletal muscle dys-function with aging. Curr Aging Sci 2011;4:101-109.
    • (2011) Curr Aging Sci , vol.4 , pp. 101-109
    • Aoi, W.1    Sakuma, K.2
  • 24
    • 59249098656 scopus 로고    scopus 로고
    • Oxidative stress in rats fed a high-fat high-sucrose diet and preventive eff ect of polyphenols: Involvement of mitochondrial and NAD(P)H oxi-dase systems
    • Feillet-Coudray C, Sutra T, Fouret G, Ramos J, Wrutniak-Cabello C, Cabello G, Cristol JP, Coudray C. Oxidative stress in rats fed a high-fat high-sucrose diet and preventive eff ect of polyphenols: involvement of mitochondrial and NAD(P)H oxi-dase systems. Free Radic Biol Med 2009;46:624-632.
    • (2009) Free Radic Biol Med , vol.46 , pp. 624-632
    • Feillet-Coudray, C.1    Sutra, T.2    Fouret, G.3    Ramos, J.4    Wrutniak-Cabello, C.5    Cabello, G.6    Cristol, J.P.7    Coudray, C.8
  • 25
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quanti-tation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quanti-tation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0002504354 scopus 로고
    • Measurement of plasma sulfhydryl and car-bonyl groups as a possible indicator of protein oxidation
    • Favier A, Cadet J, Kalyanaraman B, Fontecave M, Pierre J (eds) Basel (Switzerland): Birkhauser Verlag
    • Faure P, Lafond J. Measurement of plasma sulfhydryl and car-bonyl groups as a possible indicator of protein oxidation. In: Favier A, Cadet J, Kalyanaraman B, Fontecave M, Pierre J (eds). Analysis of free radicals in biological systems. Basel (Switzerland): Birkhauser Verlag; 1995. pp. 237-248.
    • (1995) Analysis of Free Radicals in Biological Systems , pp. 237-248
    • Faure, P.1    Lafond, J.2
  • 29
    • 0019167355 scopus 로고
    • Griffi th OW.
    • Griffi th OW. Determination of glutathione and glutathione disulfi de using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207-212.
    • (1980) Anal Biochem , vol.106 , pp. 207-212
  • 30
    • 41049100518 scopus 로고
    • A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase
    • Beers R, Sizer I. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952;195:133-140.
    • (1952) J Biol Chem , vol.195 , pp. 133-140
    • Beers, R.1    Sizer, I.2
  • 31
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • Flohe L, Gunzler WA. Assays of glutathione peroxidase. Meth-odsEnzymol 1984;105:114-121. (Pubitemid 14165378)
    • (1984) Methods in Enzymology , vol.VOL. 105 , pp. 114-121
    • Flohe, L.1    Gunzler, W.A.2
  • 32
    • 0017089936 scopus 로고
    • Spectrophotometric study of spontaneous dispro-portionation of superoxide anion radical and sensitive direct assay for superoxide dismutase
    • Marklund S. Spectrophotometric study of spontaneous dispro-portionation of superoxide anion radical and sensitive direct assay for superoxide dismutase. J Biol Chem 1976;251:7504-7507.
    • (1976) J Biol Chem , vol.251 , pp. 7504-7507
    • Marklund, S.1
  • 35
    • 2042432480 scopus 로고
    • Cytochrome oxidase from beef heart mitochondria
    • Wharton D, Tzagoloff A. Cytochrome oxidase from beef heart mitochondria. Methods Enzymol 1967;10:245-250.
    • (1967) Methods Enzymol , vol.10 , pp. 245-250
    • Wharton, D.1    Tzagoloff, A.2
  • 36
    • 77957010982 scopus 로고
    • Citrate synthase
    • Srere P. Citrate synthase. Methods Enzymol 1969;13:3-11.
    • (1969) Methods Enzymol , vol.13 , pp. 3-11
    • Srere, P.1
  • 37
    • 79952163577 scopus 로고    scopus 로고
    • Inhibition of xanthine oxidase reduces hyperglycemia-induced oxidative stress and improves mito-chondrial alterations in skeletal muscle of diabetic mice
    • Bravard A, Bonnard C, Durand A, Chauvin MA, Favier R, Vidal H, Rieusset J. Inhibition of xanthine oxidase reduces hyperglycemia-induced oxidative stress and improves mito-chondrial alterations in skeletal muscle of diabetic mice. Am J Physiol Endocrinol Metab 2011;300:E581-E591.
    • (2011) Am J Physiol Endocrinol Metab , vol.300
    • Bravard, A.1    Bonnard, C.2    Durand, A.3    Chauvin, M.A.4    Favier, R.5    Vidal, H.6    Rieusset, J.7
  • 38
    • 0016746337 scopus 로고
    • Muscle fi bre type pop-ulations of human leg muscles
    • Edgerton VR, Smith JL, Simpson DR. Muscle fi bre type pop-ulations of human leg muscles. Histochem J 1975;7:259-266.
    • (1975) Histochem J , vol.7 , pp. 259-266
    • Edgerton, V.R.1    Smith, J.L.2    Simpson, D.R.3
  • 39
    • 0016872507 scopus 로고
    • A morphometric study of age-dependent changes in mitochondrial population of mouse liver and heart
    • Herbener GH. A morphometric study of age-dependent changes in mitochondrial population of mouse liver and heart. J Gerontol 1976;31:8-12.
    • (1976) J Gerontol , vol.31 , pp. 8-12
    • Herbener, G.H.1
  • 43
    • 77956242964 scopus 로고    scopus 로고
    • Vascular oxidative stress and infl ammation increase with age: Ameliorating eff ects of alpha-lipoic acid supplementation
    • Li L, Smith A, Hagen TM, Frei B. Vascular oxidative stress and infl ammation increase with age: ameliorating eff ects of alpha-lipoic acid supplementation. Ann NY Acad Sci 2010;1203:151-159.
    • (2010) Ann NY Acad Sci , vol.1203 , pp. 151-159
    • Li, L.1    Smith, A.2    Hagen, T.M.3    Frei, B.4
  • 45
    • 79955647610 scopus 로고    scopus 로고
    • Age-related changes in renal expression of oxidant and anti-oxidant enzymes and oxidative stress markers in male SHR and WKY rats
    • Simao S, Gomes P, Pinto V, Silva E, Amaral JS, Igreja B, et al. Age-related changes in renal expression of oxidant and anti-oxidant enzymes and oxidative stress markers in male SHR and WKY rats. Exp Gerontol 2011.
    • (2011) Exp Gerontol
    • Simao, S.1    Gomes, P.2    Pinto, V.3    Silva, E.4    Amaral, J.S.5    Igreja, B.6
  • 46
    • 70349719148 scopus 로고    scopus 로고
    • Aging increases oxidative stress and renal expression of oxi-dant and antioxidant enzymes that are associated with an increased trend in systolic blood pressure
    • Gomes P, Simao S, Silva E, Pinto V, Amaral JS, Afonso J, et al. Aging increases oxidative stress and renal expression of oxi-dant and antioxidant enzymes that are associated with an increased trend in systolic blood pressure. Oxid Med Cell Longev 2009;2:138-145.
    • (2009) Oxid Med Cell Longev , vol.2 , pp. 138-145
    • Gomes, P.1    Simao, S.2    Silva, E.3    Pinto, V.4    Amaral, J.S.5    Afonso, J.6
  • 47
    • 33847620225 scopus 로고    scopus 로고
    • Aging: A revisited theory based on free radicals generated by NOX family NADPH oxidases
    • Krause KH. Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases. Exp Gerontol 2007;42:256-262.
    • (2007) Exp Gerontol , vol.42 , pp. 256-262
    • Krause, K.H.1
  • 48
    • 0028301919 scopus 로고
    • Xanthine oxidase activity and lipid peroxide content following different types of ischemia in the isolated rat heart
    • DOI 10.1007/BF02001908
    • Coudray C, Boucher F, Pucheu S, de Leiris J, Favier A. Xanthine oxidase activity and lipid peroxide content following diff erent types of ischemia in the isolated rat heart. Agents Actions 1994;41:144-150. (Pubitemid 24170598)
    • (1994) Agents and Actions , vol.41 , Issue.3-4 , pp. 144-150
    • Coudray, C.1    Boucher, F.2    Pucheu, S.3    De Leiris, J.4    Favier, A.5
  • 49
    • 0026450792 scopus 로고
    • Ischemia and reperfusion injury in isolated rat heart: Eff ect of reperfusion duration on xanthine oxidase, lipid peroxidation, and enzyme antioxidant systems in myocardium
    • Coudray C, Pucheu S, Boucher F, de Leiris J, Favier A. Ischemia and reperfusion injury in isolated rat heart: eff ect of reperfusion duration on xanthine oxidase, lipid peroxidation, and enzyme antioxidant systems in myocardium. Basic Res Cardiol 1992;87:478-488.
    • (1992) Basic Res Cardiol , vol.87 , pp. 478-488
    • Coudray, C.1    Pucheu, S.2    Boucher, F.3    De Leiris, J.4    Favier, A.5
  • 50
    • 36048983398 scopus 로고    scopus 로고
    • Age-related increase in xanthine oxidase activity in human plasma and rat tissues
    • DOI 10.1080/10715760701481461, PII 782740962
    • Aranda R, Domenech E, Rus AD, Real JT, Sastre J, Vina J, Pallardo FV. Age-related increase in xanthine oxidase activity in human plasma and rat tissues. Free Radic Res 2007;41: 1195-1200. (Pubitemid 350090773)
    • (2007) Free Radical Research , vol.41 , Issue.11 , pp. 1195-1200
    • Aranda, R.1    Domenech, E.2    Rus, A.D.3    Real, J.T.4    Sastre, J.5    Vina, J.6    Pallardo, F.7
  • 51
    • 0033582522 scopus 로고    scopus 로고
    • Binding of xanthine oxidase to vas-cular endothelium. Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling
    • Houston M, Estevez A, Chumley P, Aslan M, Marklund S, Parks DA, Freeman BA. Binding of xanthine oxidase to vas-cular endothelium. Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling. J Biol Chem 1999;274:4985-4994.
    • (1999) J Biol Chem , vol.274 , pp. 4985-4994
    • Houston, M.1    Estevez, A.2    Chumley, P.3    Aslan, M.4    Marklund, S.5    Parks, D.A.6    Freeman, B.A.7
  • 53
    • 37349110355 scopus 로고    scopus 로고
    • Metabolic adaptations through the PGC-1alpha and SIRT1 pathways
    • DOI 10.1016/j.febslet.2007.11.034, PII S0014579307011787
    • Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett 2008;582:46-53. (Pubitemid 350297246)
    • (2008) FEBS Letters , vol.582 , Issue.1 , pp. 46-53
    • Rodgers, J.T.1    Lerin, C.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 54
    • 78851470225 scopus 로고    scopus 로고
    • Resveratrol and life extension
    • Agarwal B, Baur JA. Resveratrol and life extension. Ann N Y Acad Sci 2011;1215:138-143;.
    • (2011) Ann N y Acad Sci , vol.1215 , pp. 138-143
    • Agarwal, B.1    Baur, J.A.2
  • 56
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • DOI 10.1016/j.cmet.2005.05.004, PII S1550413105001427
    • Lin J, Handschin C, Spiegelman BM. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005;1:361-370. (Pubitemid 43960626)
    • (2005) Cell Metabolism , vol.1 , Issue.6 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 59
    • 79953738995 scopus 로고    scopus 로고
    • The role and regulation of MAFbx/atrogin-1 and MuRF1 in skel-etal muscle atrophy
    • Foletta VC, White LJ, Larsen AE, Leger B, Russell AP. The role and regulation of MAFbx/atrogin-1 and MuRF1 in skel-etal muscle atrophy. Pflugers Arch 2011;461:325-335.
    • (2011) Pflugers Arch , vol.461 , pp. 325-335
    • Foletta, V.C.1    White, L.J.2    Larsen, A.E.3    Leger, B.4    Russell, A.P.5
  • 60
    • 63349112144 scopus 로고    scopus 로고
    • Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes
    • Hemdan DI, Hirasaka K, Nakao R, Kohno S, Kagawa S, Abe T, et al. Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. J Med Invest 2009;56:26-32.
    • (2009) J Med Invest , vol.56 , pp. 26-32
    • Hemdan, D.I.1    Hirasaka, K.2    Nakao, R.3    Kohno, S.4    Kagawa, S.5    Abe, T.6
  • 61
    • 77952586060 scopus 로고    scopus 로고
    • Mitochondrial fi ssion and remodelling con-tributes to muscle atrophy
    • Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C Petersen Y, et al. Mitochondrial fi ssion and remodelling con-tributes to muscle atrophy. EMBO J 2010;29:1774-1785.
    • (2010) EMBO J , vol.29 , pp. 1774-1785
    • Romanello, V.1    Guadagnin, E.2    Gomes, L.3    Roder, I.4    Sandri Petersen, C.Y.5
  • 64
    • 84868008659 scopus 로고    scopus 로고
    • Autophagy, polyphenols and healthy ageing
    • Apr 6. Epub ahead of print
    • Pallauf K, Rimbach G. Autophagy, polyphenols and healthy ageing. Ageing Res Rev Apr 6. Epub ahead of print.
    • Ageing Res Rev
    • Pallauf, K.1    Rimbach, G.2
  • 65
    • 73949099327 scopus 로고    scopus 로고
    • Increased muscle PGC-1alpha expression protects from sarco-penia and metabolic disease during aging
    • Wenz T, Rossi SG, Rotundo RL, Spiegelman BM, Moraes CT. Increased muscle PGC-1alpha expression protects from sarco-penia and metabolic disease during aging. Proc Natl Acad Sci USA 2009106:20405-20410.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20405-20410
    • Wenz, T.1    Rossi, S.G.2    Rotundo, R.L.3    Spiegelman, B.M.4    Moraes, C.T.5
  • 66
    • 65549139675 scopus 로고    scopus 로고
    • Regulation of the aging process by autophagy
    • Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med 2009;15:217-224.
    • (2009) Trends Mol Med , vol.15 , pp. 217-224
    • Salminen, A.1    Kaarniranta, K.2


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