Amla (Emblica officinalis Gaertn.) attenuates age-related renal dysfunction by oxidative stress

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 19, 2007, Pages 7744-7752

  Yokozawa, Takako ^a   Hyun, Young Kim ^a   Hyun, Ju Kim ^a   Tanaka, Takashi ^b   Sugino, Hidetoshi ^c   Okubo, Tsutomu ^c   Chu, Djong Chi ^c   Lekh, Raj Juneja ^c  

^a UNIVERSITY OF TOYAMA   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c TAIYO KAGAKU CO LTD   (Japan)

Author keywords

Aging; Amla; Bax; COX 2; INOS; Kidney; NF B; Rat; TBA reactive substance

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; FLAVONOID; INDUCIBLE NITRIC OXIDE SYNTHASE; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; UNCLASSIFIED DRUG;

AGING; ANIMAL; ARTICLE; BLOOD PRESSURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; EMBLICA OFFICINALIS; KIDNEY DISEASE; MALE; OXIDATIVE STRESS; RAT;

AGING; ANIMALS; BLOOD PRESSURE; CYCLOOXYGENASE 2 INHIBITORS; FLAVONOIDS; KIDNEY DISEASES; MALE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PHENOLS; PHYLLANTHUS EMBLICA; PLANT EXTRACTS; RATS;

PHYLLANTHUS EMBLICA; RATTUS;

EID: 34948906694     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf072105s     Document Type: Article

References (46)

1. Anila, L.; Vijayalakshmi, N. R. Flavonoids from Emblica officinalis and Mangifera indica-effectiveness for dyslipidemia. J. Ethnopharmacol. 2002, 79, 81-87.
2. Sabu, M. C.; Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J. Ethnopharmacol. 2002, 81, 155-160.
3. Asmawi, M. Z.; Kankaanranta, H.; Moilanen, E.; Vapaatalo, H. Anti-inflammatory activities of Emblica officinalis Gaertn. leaf extracts. J. Pharm. Pharmacol. 1993, 45, 581-584.
4. El-Mekkawy, S.; Meselhy, M. R.; Kusumoto, I. T.; Kadota, S.; Hattori, M.; Namba, T. Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase. Chem. Pharm. Bull. 1995, 43, 641-648.
5. Jose, J. K.; Kuttan, G.; Kuttan, R. Antitumor activity of Emblica officinalis. J. Ethnopharmacol. 2001, 75, 65-69.
6. Bandyopadhyay, S. K.; Pakrashi, S. C.; Pakrashi, A. The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer. J. Ethnopharmacol. 2000, 70, 171-176.
7. Anila, L.; Vijayalakshmi, N. R. Antioxidant action of flavonoids from Mangifera indica and Emblica officinalis in hypercholesterolemic rats. Food Chem. 2003, 83, 569-574.
8. Jose, J. K.; Kuttan, R. Antioxidant activity of E. officinalis. J. Clin. Biochem. Nutr. 1995, 19, 63-70.
9. Kim, H. J.; Yokozawa, T.; Kim, H. Y.; Tohda, C.; Rao, T. P.; Juneja, L. R. Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats. J. Nutr. Sci. Vitaminol. 2005, 51, 413-418.
10. Beckman, K. B.; Ames, B. N. The free radical theory of aging nature. Physiol. Rev. 1998, 78, 547-581.
11. Yu, B. P.; Chung, H. Y. Oxidative stress and vascular aging. Diabetes Res. Clin. Pract. 2001, 54, S73-S80.
12. Baylis, C.; Corman, B. The aging kidney. Insights from experimental studies. J. Am. Soc. Nephrol. 1998, 9, 699-709.
13. Lamb, E. J.; O'Riordan, S. E.; Delaney, M. P. Kidney function in older people: Pathology, assessment and management. Clin. Chim. Acta 2003, 334, 25-40.
14. Fliser, D.; Franek, E.; Joest, M.; Block, S.; Mutschler, E.; Ritz, E. Renal function in the elderly: impact of hypertension and cardiac function. Kidney Int. 1997, 51, 1196-1204.
15. Schreck, R.; Albermann, K.; Baeuerle, P. A. Nuclear factor kappa B: an oxidative stress responsive transcription factor of eukaryotic cells (a review). Free Radical Res. Commun. 1992, 17, 221-237.
16. Reckelhoff, J. F.; Hennington, B. S.; Kanji, V.; Racusen, L. C.; Schmidt, A. M.; Yan, S. D.; Morrow, J.; Roberts, L. J., 2nd; Salahudeen, A. K. Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats. Am. J. Hypertens. 1999, 12, 492-498.
17. Dilley, R. J.; Nataatmadja, M. I. Heparin inhibits mesenteric vascular hypertrophy in angiotensin II-infusion hypertension in rats. Cardiovasc. Res. 1998, 38, 247-255.
18. Johnson, D.; Lardy, H. Isolation of liver or kidney mitochondria. Methods Enzymol. 1967, 10, 94-96.
19. Jung, K.; Pergande, M. Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria. FEBS Lett. 1985, 183, 167-169.
20. Buege, J. A.; Aust, S. D. Microsomal lipid peroxidation. Methods Enzymol. 1978, 52, 302-306.
21. Itzhaki, R. F.; Gill, D. M. A micro-biuret method for estimating proteins. Anal. Biochem. 1964, 9, 401-410.
22. Laemmli, U. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
23. Sakurai, H.; Hisada, Y.; Ueno, M.; Sugiura, M.; Kawashima, K.; Sugita, T. Activation of transcription factor NF-κB in experimental glomerulonephritis in rats. Biochim. Biophys. Acta 1996, 1316, 132-138.
24. Zhang, Y.; Tanaka, T.; Yang, C.; Kouno, I. New phenolic constituents from the fruit juice of Phyllanthus emblica. Chem. Pharm. Bull. 2001, 49, 537-540.
25. Khan, I. H.; Catto, G. R.; Edward, N.; MacLeod, A. M. Acute renal failure: factors influencing nephrology referral and outcome. QJM 1997, 90, 781-785.
26. Li, Y. M.; Steffes, M.; Donnelly, T.; Liu, C; Fuh, H.; Basgen, J.; Bucala, R.; Vlassara, H. Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 3902-3907.
27. Adler, S.; Huang, H.; Wolin, M. S.; Kaminski, P. M. Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney. J. Am. Soc. Nephrol. 2004, 15, 52-60.
28. Leibovitz, B. E.; Siegel, B. V. Aspects of free radical reaction in biological systems; aging. J. Gerontol. 1990, 35, 45-56.
29. de la Lastra, C. A.; Villegas, I. Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications. Mol. Nutr. Food Res. 2005, 49, 405-430.
30. Kannel, W. B.; Wolf, P. A.; McGee, D. L.; Dawber, T. R.; McNamara, P.; Castelli, W. P. Systolic blood pressure, arterial rigidity, and risk of stroke. The Framingham Study. JAMA 1981, 245, 1225-1229.
31. Cavanagh, E. M. V.; Piotrkowski, B.; Basso, N.; Stella, I.; Inserra, F.; Ferder, L.; Fraga, C. G. Enalapril and losartan attenuate mitochondrial dysfunction in aged rats. FASEB J. 2003, 17, 1096-1098.
32. Halliwell, B.; Chirico, S. Lipid peroxidation: its mechanism measurement and significance. Am. J. Clin. Nutr. 1993, 57, 715-725.
33. Ruiz-Torres, M. P.; Bosch, R. J.; O'Valle, F.; Del Moral, R. G.; Ramirez, C.; Masseroli, M.; Perez-Caballero, C.; Iglesias, M. C.; Rodriguez-Puyol, M.; Rodriguez-Puyol, D. Age-related increase in expression of TGF-beta1 in the rat kidney: Relationship to morphologic changes. J. Am. Soc. Nephrol. 1998, 9, 782-791.
34. Cruz, C. I.; Ruiz-Torres, P.; del Moral, R. G.; Rodriguez-Puyol, M.; Rodriguez-Puyol, D. Age-related progressive renal fibrosis in rats and its prevention with ACE inhibitors and taurine. Am. J. Physiol. Renal Physiol. 2000, 278, F122-F129.
35. Wu, C. C.; Hong, H. J.; Chou, T. C.; Ding, Y. A.; Yen, M. H. Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats. Biochem. Biophys. Res. Commun. 1996, 228, 459-466.
36. Chou, T. C.; Yen, M. H.; Li, C. Y.; Ding, Y. A. Alterations of nitric oxide synthase expression with aging and hypertension in rats. Hypertension 1998, 31, 643-648.
37. Vaziri, N. D.; Ni, Z.; Oveisi, F.; Trnavsky-Hobbs, D. L. Effect of antioxidant therapy on blood pressure and NO synthase expression in hypertensive rats. Hypertension 2000, 36, 957-964.
38. Araujo, M.; Welch, W. J. Oxidative stress and nitric oxide in kidney function. Curr. Opin. Nephrol. Hypertens. 2006, 15, 72-77.
39. Hong, H. J.; Loh, S. H.; Yen, M. H. Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase. Br. J. Pharmacol. 2000, 131, 631-637.
40. Hockenbery, D. M.; Oltvai, Z. N.; Yin, X. M.; Milliman, C. L.; Korsmeyer, S. J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993, 75, 241-251.
41. Green, D. R.; Reed, J. C. Mitochondria and apoptosis. Science 1998, 281, 1309-1312.
42. Samhan-Arias, A. K.; Martín-Romero, F. J.; Gutiérrez- Merino, C. Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis. Free Radical Biol. Med. 2004, 37, 48-61.
43. Chung, H. Y.; Kim, H. J.; Kim, K. W.; Choi, J. S.; Yu, B. P. Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction. Microsc. Res. Technol. 2002, 59, 264-272.
44. Spencer, N. F.; Poynter, M. E.; Im, S. Y.; Daynes, R. A. Constitutive activation of NF-κB in an animal model of aging. Int. Immunol. 1997, 9, 1581-1588.
45. Li, Q.; Verma, I. M. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2002, 2, 725-734.
46. Lavrovsky, Y.; Chatterjee, B.; Clark, R. A.; Roy, A. K. Role of redox-regulated transcription factors in inflammation, aging and age-related diseases. Exp. Gerontol. 2000, 35, 521-532.