Random mtDNA deletions and functional consequence in aged human skeletal muscle

Biochemical and Biophysical Research Communications

Volumn 332, Issue 2, 2005, Pages 542-549

  Chabi, Béatrice ^a   Mousson De Camaret, Bénédicte ^b   Chevrollier, Arnaud ^c   Boisgard, Stéphane ^d   Stepien, Georges ^e  

^a INRA and University of Auvergne   (France)

^b HÔPITAL DEBROUSSE   (France)

^c UNIVERSITÉ D'ANGERS   (France)

^d SERVICE DE RHUMATOLOGIE   (France)

^e INSERM   (France)

Author keywords

Aging; Mitochondria; mtDNA deletion; Oxidative phosphorylation; Respiratory chain

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; AGED; AGING; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; GENE FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL RESPIRATION; MUSCLE BIOPSY; NORMAL HUMAN; PHYSICAL ACTIVITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SKELETAL MUSCLE; SOUTHERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGING; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; FEMALE; GENE DELETION; HUMANS; MALE; MUSCLE, SKELETAL; STATISTICS;

EID: 19444373676     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.04.153     Document Type: Article

References (40)

1. I. Trounce, E. Byrne, and S. Marzuki Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing Lancet 1 1989 637 639
2. J.M. Cooper, V.M. Mann, and A.H. Schapira Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing J. Neurol. Sci. 113 1992 91 98
3. T.C. Yen, Y.S. Chen, K.L. King, S.H. Yeh, and Y.H. Wei Liver mitochondrial respiratory functions decline with age Biochem. Biophys. Res. Commun. 165 1989 944 1003
4. J. Ojaimi, C.L. Masters, K. Opeskin, P. McKelvie, and E. Byrne Mitochondrial respiratory chain activity in the human brain as a function of age Mech. Ageing Dev. 111 1999 39 47
5. D. Harman The aging process Proc. Natl. Acad. Sci. USA 78 1981 7124 7128
6. D.C. Wallace, G. Singh, M.T. Lott, J.A. Hodge, T.G. Schurr, A.M. Lezza, L.J. Elsas, and E.K. Nikoskelainen Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy Science 242 1988 1427 1430
7. I.J. Holt, A.E. Harding, and J.A. Morgan-Hughes Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies Nature 331 1988 717 719
8. G. Cortopassi, D. Shibata, N. Soong, and N. Arnheim A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues Proc. Natl. Acad. Sci. USA 89 1992 7370 7374
9. S. Simonetti, X. Chen, S. DiMauro, and E.A. Schon Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR Biochim. Biophys. Acta 1180 1992 113 122
10. G. Biagini, F. Pallotti, S. Carraro, G. Sgarbi, M.M. Pich, G. Lenaz, F. Anzivino, G. Gualandi, and D. Xin Mitochondrial DNA in platelets from aged subjects Mech. Ageing Dev. 101 1998 269 275
11. G.S. Gerhard, F.A. Benko, R.G. Allen, M. Tresini, A. Kalbach, V.J. Cristofalo, and C.D. Gocke Mitochondrial DNA mutation analysis in human skin fibroblasts from fetal, young, and old donors Mech. Ageing Dev. 123 2002 155 166
12. C. Zhang, A.W. Linnane, and P. Nagley Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans Biochem. Biophys. Res. Commun. 195 1993 1104 1110
13. C. Munscher, T. Rieger, J. Muller_Hocker, and B. Kadenbach The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages FEBS Lett. 317 1993 27 30
14. H.C. Lee, C.Y. Pang, H.S. Hsu, and Y.H. Wei Differential accumulations of 4977 bp deletion in mitochondrial DNA of various tissues in human ageing Biochim. Biophys. Acta 1226 1994 37 43
15. S. Melov, J.M. Shoffner, A. Kaufman, and D.C. Wallace Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle Nucleic Acids Res. 23 1995 4122 4126
16. M. Hayakawa, K. Katsumata, M. Yoneda, M. Tanaka, S. Sugiyama, and T. Ozawa Age-related extensive fragmentation of mitochondrial DNA into minicircles Biochem. Biophys. Res. Commun. 226 1996 369 377
17. S.A. Kovalenko, G. Kopsidas, J.M. Kelso, and A.W. Linnane Deltoid human muscle mtDNA is extensively rearranged in old age subjects Biochem. Biophys. Res. Commun. 232 1997 147 152
18. A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, Y.M. Bohlooly, S. Gidlof, A. Oldfors, R. Wibom, J. Tornell, H.T. Jacobs, and N.G. Larsson Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423
19. Y. Wang, Y. Michikawa, C. Mallidis, Y. Bai, L. Woodhouse, K.E. Yarasheski, C.A. Miller, V. Askanas, W.K. Engel, S. Bhasin, and G. Attardi Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication Proc. Natl. Acad. Sci. USA 98 2001 4022 4027
20. M.T. Lin, D.K. Simon, C.H. Ahn, L.M. Kim, and M.F. Beal High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain Hum. Mol. Genet. 11 2002 133 145
21. P. Reynier, and Y. Malthiery Accumulation of deletions in MtDNA during tissue aging: analysis by long PCR Biochem. Biophys. Res. Commun. 217 1995 59 67
22. B. Chabi, B. Mousson de Camaret, H. Duborjal, J.P. Issartel, and G. Stepien Quantification of mitochondrial DNA deletion, depletion, and overreplication: application to diagnosis Clin. Chem. 49 2003 1309 1317
23. T. Ferlin, G. Guironnet, M.C. Barnoux, R. Dumoulin, G. Stepien, and B. Mousson Detection of mitochondrial DNA deletions by a screening procedure using the polymerase chain reaction Mol. Cell. Biochem. 174 1997 221 225
24. B. Mousson, J.M. Collombet, R. Dumoulin, H. Carrier, F. Flocard, M. Bouzidi, C. Godinot, I. Maire, M. Mathieu, and S. Quard An abnormal exercise test response revealing a respiratory chain complex III deficiency Acta Neurol. Scand. 91 1995 488 493
25. R.H. Hsieh, J.H. Hou, H.S. Hsu, and Y.H. Wei Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria Biochem. Mol. Biol. Int. 32 1994 1009 1022
26. A.M. Lezza, D. Boffoli, S. Scacco, P. Cantatore, and M.N. Gadaleta Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles Biochem. Biophys. Res. Commun. 205 1994 772 779
27. D. Boffoli, S.C. Scacco, R. Vergari, G. Solarino, G. Santacroce, and S. Papa Decline with age of the respiratory chain activity in human skeletal muscle Biochim. Biophys. Acta 1226 1994 73 82
28. C.T. Moraes, S. DiMauro, M. Zeviani, A. Lombes, S. Shanske, A.F. Miranda, H. Nakase, E. Bonilla, L.C. Werneck, and S. Servidei Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome N. Engl. J. Med. 320 1989 1293 1299
29. D.C. Wallace Mitochondrial DNA sequence variation in human evolution and disease Proc. Natl. Acad. Sci. USA 91 1994 8739 8746
30. K. Khrapko, E. Nekhaeva, Y. Kraytsberg, and W. Kunz Clonal expansions of mitochondrial genomes: implications for in vivo mutational spectra Mutat. Res. 522 2003 13 19
31. J. Hayashi, M. Takemitsu, Y. Goto, and I. Nonaka Human mitochondria and mitochondrial genome function as a single dynamic cellular unit J. Cell Biol. 125 1994 43 50
32. F. Legros, F. Malka, P. Frachon, A. Lombes, and M. Rojo Organization and dynamics of human mitochondrial DNA J. Cell Sci. 117 2004 2653 2662
33. V. Geromel, B. Parfait, J.C. von Kleist-Retzow, D. Chretien, A. Munnich, A. Rotig, and P. Rustin The consequences of a mild respiratory chain deficiency on substrate competitive oxidation in human mitochondria Biochem. Biophys. Res. Commun. 236 1997 643 646
34. K.J. Davies, L. Packer, and G.A. Brooks Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training Arch. Biochem. Biophys. 209 1981 539 554
35. P. Berthon, D. Freyssenet, J.C. Chatard, J. Castells, I. Mujika, A. Geyssant, C.Y. Guezennec, and C. Denis Mitochondrial ATP production rate in 55 to 73-year-old men: effect of endurance training Acta Physiol. Scand. 154 1995 269 274
36. J.A. Baecke, J. Burema, and J.E. Frijters A short questionnaire for the measurement of habitual physical activity in epidemiological studies Am. J. Clin. Nutr. 36 1982 936 942
37. O.E. Rooyackers, A.H. Kersten, and A.J. Wagenmakers Mitochondrial protein content and in vivo synthesis rates in skeletal muscle from critically ill rats Clin. Sci. (Lond.) 91 1996 475 481
38. G. Paradies, G. Petrosillo, M. Pistolese, and F.M. Ruggiero Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage Gene 286 2002 135 141
39. S. Anderson, A.T. Bankier, B.G. Barrell, M.H. de Bruijn, A.R. Coulson, J. Drouin, I.C. Eperon, D.P. Nierlich, B.A. Roe, F. Sanger, P.H. Schreier, A.J. Smith, R. Staden, and I.G. Young Sequence and organization of the human mitochondrial genome Nature 290 1981 457 465
40. N. Neckelmann, C.K. Warner, A. Chung, J. Kudoh, S. Minoshima, R. Fukuyama, M. Maekawa, Y. Shimizu, N. Shimizu, and J.D. Liu The human ATP synthase beta subunit gene: sequence analysis, chromosome assignment, and differential expression Genomics 5 1989 829 843