메뉴 건너뛰기




Volumn 64, Issue 6, 2012, Pages 549-556

Modulatory effects of vitamin E, acetyl-l-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model

Author keywords

Alzheimer's disease; Dietary supplements; Homocysteine; Inflammatory cytokines; Insulin; Insulin like growth factor

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA TOCOPHEROL; CYANOCOBALAMIN; DONEPEZIL; FOLIC ACID; HOMOCYSTEINE; INSULIN; INTERLEUKIN 1BETA; LEVACECARNINE; SOMATOMEDIN C; THIOCTIC ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 84864500549     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2010.11.012     Document Type: Article
Times cited : (32)

References (92)
  • 1
    • 0033607450 scopus 로고    scopus 로고
    • Alpha-lipoic acid prevents 3,4-methyienedioxymethaphetamine (MDMA)-induced neurotoxicity
    • Aguirre N., Barrionuevo M., Ramirez M.J., Del Rio J., Lasheras B. Alpha-lipoic acid prevents 3,4-methyienedioxymethaphetamine (MDMA)-induced neurotoxicity. Neuroreport 1999, 10:3675-3680.
    • (1999) Neuroreport , vol.10 , pp. 3675-3680
    • Aguirre, N.1    Barrionuevo, M.2    Ramirez, M.J.3    Del Rio, J.4    Lasheras, B.5
  • 2
    • 0021276510 scopus 로고
    • Correlation between cortical plaque count and neuronal loss in the nucleus basalis in Alzheimer's disease
    • Arendt T., Bigl V., Tennstedt A., Arendt A. Correlation between cortical plaque count and neuronal loss in the nucleus basalis in Alzheimer's disease. Neurosci Lett 1984, 48:81-85.
    • (1984) Neurosci Lett , vol.48 , pp. 81-85
    • Arendt, T.1    Bigl, V.2    Tennstedt, A.3    Arendt, A.4
  • 3
    • 83355173783 scopus 로고    scopus 로고
    • Modification of platelets from Alzheimer disease patients: a possible relation between membrane properties and NO metabolites
    • Arianna V., Laura N., Moroni C., Laura T., Marco B., Simona L., et al. Modification of platelets from Alzheimer disease patients: a possible relation between membrane properties and NO metabolites. J Neurobiol Aging 2006, 30:1-8.
    • (2006) J Neurobiol Aging , vol.30 , pp. 1-8
    • Arianna, V.1    Laura, N.2    Moroni, C.3    Laura, T.4    Marco, B.5    Simona, L.6
  • 5
    • 4344617955 scopus 로고    scopus 로고
    • Neuroprotective effect of l-carnitine in the 3-nitropropionic acid (3-NPA)-evoked neurotoxicity in rats
    • Binienda Z., Virman A., Przybyla-Zawislak B., Schmued L. Neuroprotective effect of l-carnitine in the 3-nitropropionic acid (3-NPA)-evoked neurotoxicity in rats. Neurosci Lett 2004, 367:264-267.
    • (2004) Neurosci Lett , vol.367 , pp. 264-267
    • Binienda, Z.1    Virman, A.2    Przybyla-Zawislak, B.3    Schmued, L.4
  • 6
    • 0345257085 scopus 로고    scopus 로고
    • The mitochondriotropic effects of l-carnitine and its esters in the central nervous system
    • Binienda Z., Virmani A. The mitochondriotropic effects of l-carnitine and its esters in the central nervous system. Curr Med Chem Cent Nerv Syst Agents 2003, 3:275-282.
    • (2003) Curr Med Chem Cent Nerv Syst Agents , vol.3 , pp. 275-282
    • Binienda, Z.1    Virmani, A.2
  • 7
    • 68949146104 scopus 로고
    • The effect of subacute doses of organophosphorus pesticide, nuvacron, on the biochemical and cytogenetic parameters of mice and their embryos
    • Blawen D.H., Poppe W.A., Trischler W. The effect of subacute doses of organophosphorus pesticide, nuvacron, on the biochemical and cytogenetic parameters of mice and their embryos. J Clin Chem Biochem 1983, 21:381-386.
    • (1983) J Clin Chem Biochem , vol.21 , pp. 381-386
    • Blawen, D.H.1    Poppe, W.A.2    Trischler, W.3
  • 8
    • 0027308906 scopus 로고
    • Serum levels of insulin-like growth factor-1 (IGF-1) and IGF binding protein 3 reflect spontaneous growth hormone secretion
    • Blum W.F., Albertsson-Wikland K., Rosberg S., Rank M.B. Serum levels of insulin-like growth factor-1 (IGF-1) and IGF binding protein 3 reflect spontaneous growth hormone secretion. J Clin Endocrinol Metab 1993, 76:1610-1616.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1610-1616
    • Blum, W.F.1    Albertsson-Wikland, K.2    Rosberg, S.3    Rank, M.B.4
  • 9
    • 77956933314 scopus 로고    scopus 로고
    • TNF-receptors are associated with Aβ metabolism and conversion to dementia in subjects with mild cognitive impairment
    • Buchhave P., Zetterberg H., Blennow K., Minthon L., Janciauskiene S., Hansson O., et al. TNF-receptors are associated with Aβ metabolism and conversion to dementia in subjects with mild cognitive impairment. Neurobiol Aging 2008, 31:1877-1884.
    • (2008) Neurobiol Aging , vol.31 , pp. 1877-1884
    • Buchhave, P.1    Zetterberg, H.2    Blennow, K.3    Minthon, L.4    Janciauskiene, S.5    Hansson, O.6
  • 10
    • 0026756887 scopus 로고
    • Methodological variables in the assessment of beta-amyloid neurotoxicity
    • Busciglio J., Lorenzo A., Yankner R.A. Methodological variables in the assessment of beta-amyloid neurotoxicity. Neurobiol Aging 1992, 13:609-612.
    • (1992) Neurobiol Aging , vol.13 , pp. 609-612
    • Busciglio, J.1    Lorenzo, A.2    Yankner, R.A.3
  • 11
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin like growth factor.1 in the molecular and cellular mechanism underlying the pathology of Alzheimer's disease
    • Carro E., Torres-Aleman J. The role of insulin and insulin like growth factor.1 in the molecular and cellular mechanism underlying the pathology of Alzheimer's disease. Eur J Pharmacol 2004, 490:127-133.
    • (2004) Eur J Pharmacol , vol.490 , pp. 127-133
    • Carro, E.1    Torres-Aleman, J.2
  • 12
    • 47749122964 scopus 로고    scopus 로고
    • Dietary and genetic compromise in folate availability reduces acetylcholine and cognitive performance: critical role of S-adenosylmethionine
    • Chan A., Tchantchou F., Graves V., Rozen R., Shea T.B. Dietary and genetic compromise in folate availability reduces acetylcholine and cognitive performance: critical role of S-adenosylmethionine. J Health Nutr Aging 2008, 12:252-261.
    • (2008) J Health Nutr Aging , vol.12 , pp. 252-261
    • Chan, A.1    Tchantchou, F.2    Graves, V.3    Rozen, R.4    Shea, T.B.5
  • 14
    • 76749163675 scopus 로고    scopus 로고
    • Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in mouse model of Alzheimer's disease
    • Chavant F., Deguil J., Pain S., Ingrand I., Milin S., Fauconneau B., et al. Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in mouse model of Alzheimer's disease. J Pharmacol Exp Ther 2010, 332:505-514.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 505-514
    • Chavant, F.1    Deguil, J.2    Pain, S.3    Ingrand, I.4    Milin, S.5    Fauconneau, B.6
  • 15
    • 3242769206 scopus 로고    scopus 로고
    • Brain cholinesterases: III. Future perspective of AD research and clinical practice
    • Chen Z.X. Brain cholinesterases: III. Future perspective of AD research and clinical practice. Med Hypotheses 2004, 63:298-307.
    • (2004) Med Hypotheses , vol.63 , pp. 298-307
    • Chen, Z.X.1
  • 16
    • 77049093949 scopus 로고    scopus 로고
    • Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non demented patients
    • Cheng X., Yang L., He P., Li R., Shen Y. Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non demented patients. J Alzheimer's Dis 2010, 19:621-630.
    • (2010) J Alzheimer's Dis , vol.19 , pp. 621-630
    • Cheng, X.1    Yang, L.2    He, P.3    Li, R.4    Shen, Y.5
  • 17
    • 0037219221 scopus 로고    scopus 로고
    • Reduced hippocampal-insulin-degrading enzyme in late onset Alzheimer's disease is associated with the apolipoprotein E. epsilon 4 allele
    • Cook D.G., Leverenz J.B., McMillan P.J., Kulstad J.J., Ericksen S., Roth R.A., et al. Reduced hippocampal-insulin-degrading enzyme in late onset Alzheimer's disease is associated with the apolipoprotein E. epsilon 4 allele. Am J Pathol 2003, 162:313-319.
    • (2003) Am J Pathol , vol.162 , pp. 313-319
    • Cook, D.G.1    Leverenz, J.B.2    McMillan, P.J.3    Kulstad, J.J.4    Ericksen, S.5    Roth, R.A.6
  • 18
    • 58349119112 scopus 로고    scopus 로고
    • Systemic inflammation induces acute behavioral and cognitive changes and accelerates neuron degenerative disease
    • Cunningham C., Campion S., Lunnon K., Murray C.L., Woods J.F., Deaucon R.M., et al. Systemic inflammation induces acute behavioral and cognitive changes and accelerates neuron degenerative disease. Biol Psychiatry 2009, 65:304-312.
    • (2009) Biol Psychiatry , vol.65 , pp. 304-312
    • Cunningham, C.1    Campion, S.2    Lunnon, K.3    Murray, C.L.4    Woods, J.F.5    Deaucon, R.M.6
  • 19
    • 0036019850 scopus 로고    scopus 로고
    • Effect of long-term aluminum feeding on kinetics attributes of tissue cholinesterases
    • Dave K.R., Syal A.R., Katyare S.S. Effect of long-term aluminum feeding on kinetics attributes of tissue cholinesterases. Brain Res Bull 2002, 58:225-233.
    • (2002) Brain Res Bull , vol.58 , pp. 225-233
    • Dave, K.R.1    Syal, A.R.2    Katyare, S.S.3
  • 20
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
    • de la Monte S.M., Wands J.R. Review of insulin and insulin like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimer's Dis 2005, 7:45-61.
    • (2005) J Alzheimer's Dis , vol.7 , pp. 45-61
    • de la Monte, S.M.1    Wands, J.R.2
  • 21
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • de La Monte S.M. Insulin resistance and Alzheimer's disease. BMB Rep 2009, 42:475-481.
    • (2009) BMB Rep , vol.42 , pp. 475-481
    • de La Monte, S.M.1
  • 22
    • 0032892223 scopus 로고    scopus 로고
    • Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase
    • Devaraj S., Jialai I. Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase. Arterioscler Thromb Vasc Biol 1999, 19:1125-1133.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1125-1133
    • Devaraj, S.1    Jialai, I.2
  • 23
    • 0028593635 scopus 로고
    • The interleukin-1 family: 10 years of discovery
    • Dinarello C.A. The interleukin-1 family: 10 years of discovery. Eur Cytokine Netw 1994, 5:517-522.
    • (1994) Eur Cytokine Netw , vol.5 , pp. 517-522
    • Dinarello, C.A.1
  • 27
    • 21744462251 scopus 로고    scopus 로고
    • Homocysteine: overview of biochemistry, molecular biology, and role in disease processes
    • Fowler B. Homocysteine: overview of biochemistry, molecular biology, and role in disease processes. Semin Vasc Med 2005, 5:77-86.
    • (2005) Semin Vasc Med , vol.5 , pp. 77-86
    • Fowler, B.1
  • 28
    • 0031886747 scopus 로고    scopus 로고
    • An enzyme conversion immunoassay for determining total homocysteine in plasma or serum
    • Frantzen F., Faaren A.L., Alfheim I., Adn Nordhei A.K. An enzyme conversion immunoassay for determining total homocysteine in plasma or serum. Clin Chem 1998, 44:311-316.
    • (1998) Clin Chem , vol.44 , pp. 311-316
    • Frantzen, F.1    Faaren, A.L.2    Alfheim, I.3    Adn Nordhei, A.K.4
  • 29
    • 0019512037 scopus 로고
    • Changes in plasma renin activity after hypoglycaemia in sympathectomized man
    • Frier B.M., Corrall R.J., Pritchard J.L., Sever P.S. Changes in plasma renin activity after hypoglycaemia in sympathectomized man. Clin Sci 1981, 61:245-247.
    • (1981) Clin Sci , vol.61 , pp. 245-247
    • Frier, B.M.1    Corrall, R.J.2    Pritchard, J.L.3    Sever, P.S.4
  • 30
    • 38449123153 scopus 로고    scopus 로고
    • Effects of antioxidant supplementation on the aging process
    • Fusco D., Colloca G., LoMonaco M.R., Cesari M. Effects of antioxidant supplementation on the aging process. Clin Interv Aging 2007, 2:377-387.
    • (2007) Clin Interv Aging , vol.2 , pp. 377-387
    • Fusco, D.1    Colloca, G.2    LoMonaco, M.R.3    Cesari, M.4
  • 31
    • 75149149368 scopus 로고    scopus 로고
    • Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum
    • Garcia T., Esparza J.L., Nogués M.B., Romeu M., Domingo J.L., Gomez M. Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum. Hippocampus 2010, 20:218-225.
    • (2010) Hippocampus , vol.20 , pp. 218-225
    • Garcia, T.1    Esparza, J.L.2    Nogués, M.B.3    Romeu, M.4    Domingo, J.L.5    Gomez, M.6
  • 32
    • 0142026832 scopus 로고    scopus 로고
    • Potential roles of insulin and IGF-1-in AD
    • Gasparini I., Xu H. Potential roles of insulin and IGF-1-in AD. Trends Neurosci 2003, 26:404-406.
    • (2003) Trends Neurosci , vol.26 , pp. 404-406
    • Gasparini, I.1    Xu, H.2
  • 34
    • 0026746512 scopus 로고
    • Neuromelanin-containing neurons of the sulstantia nigra accumulate iron and aluminum in parkinson's disease: a LAMMA study
    • Good P.F., Olanow C.W., Perl D.P. Neuromelanin-containing neurons of the sulstantia nigra accumulate iron and aluminum in parkinson's disease: a LAMMA study. Brain Res 1992, 593:343-346.
    • (1992) Brain Res , vol.593 , pp. 343-346
    • Good, P.F.1    Olanow, C.W.2    Perl, D.P.3
  • 35
    • 0025231868 scopus 로고
    • Cholinotoxic effects of aluminum in rat brain
    • Gulya K., Rakonczay Z., Kasa P. Cholinotoxic effects of aluminum in rat brain. Neurochemistry 1990, 51:1020-1026.
    • (1990) Neurochemistry , vol.51 , pp. 1020-1026
    • Gulya, K.1    Rakonczay, Z.2    Kasa, P.3
  • 36
    • 77149149070 scopus 로고    scopus 로고
    • Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine induced toxicity in rat cortical neurons
    • Ho Y.S., Yu M.S., Yang X.F., So K.F., Yuen W.H., Chang R.C. Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine induced toxicity in rat cortical neurons. J Alzheimer's Dis 2010, 19:813-827.
    • (2010) J Alzheimer's Dis , vol.19 , pp. 813-827
    • Ho, Y.S.1    Yu, M.S.2    Yang, X.F.3    So, K.F.4    Yuen, W.H.5    Chang, R.C.6
  • 37
    • 33845713183 scopus 로고    scopus 로고
    • Lipoic acid as a novel treatment for Alzheimer's disease and related dementias
    • Holmquist L., Stuchbury G., Berbaum K., Muscat S., Young S., Hager K., et al. Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharmacol Ther 2007, 113:154-164.
    • (2007) Pharmacol Ther , vol.113 , pp. 154-164
    • Holmquist, L.1    Stuchbury, G.2    Berbaum, K.3    Muscat, S.4    Young, S.5    Hager, K.6
  • 38
    • 0024545260 scopus 로고
    • Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral metabolism in early onset dementia of Alzheimer type
    • Hoyer S., Nitsch R. Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral metabolism in early onset dementia of Alzheimer type. J Neural Transm 1989, 75:227-232.
    • (1989) J Neural Transm , vol.75 , pp. 227-232
    • Hoyer, S.1    Nitsch, R.2
  • 39
    • 1842785179 scopus 로고    scopus 로고
    • Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
    • Hoyer S. Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur J Pharmcol 2004, 490:115-125.
    • (2004) Eur J Pharmcol , vol.490 , pp. 115-125
    • Hoyer, S.1
  • 40
    • 0034254453 scopus 로고    scopus 로고
    • TNF alpha and the TNF receptor superfamily: structure-function relationship(s)
    • Idriss H.T., Naismith J.H. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech 2000, 50:184-195.
    • (2000) Microsc Res Tech , vol.50 , pp. 184-195
    • Idriss, H.T.1    Naismith, J.H.2
  • 41
    • 47549103898 scopus 로고    scopus 로고
    • Physiological functions of carnitine and carnitine transporters in the central nervous system
    • Inazu M., Matsumiya T. Physiological functions of carnitine and carnitine transporters in the central nervous system. Nihon Shinkei Seishin Yakurigaku Zasshi 2008, 28:113-120.
    • (2008) Nihon Shinkei Seishin Yakurigaku Zasshi , vol.28 , pp. 113-120
    • Inazu, M.1    Matsumiya, T.2
  • 42
    • 77951210035 scopus 로고    scopus 로고
    • Insulin like growth factor-1 induced processing of amyloid beta precursor protein (APP) and APP like protein 2 is mediated by different metalloproteinases
    • Jacobsen K.T., Adlerz L., Multhaup G., Iverfeldt K. Insulin like growth factor-1 induced processing of amyloid beta precursor protein (APP) and APP like protein 2 is mediated by different metalloproteinases. J Biol Chem 2010, 285:10223-10231.
    • (2010) J Biol Chem , vol.285 , pp. 10223-10231
    • Jacobsen, K.T.1    Adlerz, L.2    Multhaup, G.3    Iverfeldt, K.4
  • 43
    • 1642493734 scopus 로고    scopus 로고
    • Antagonism of anticholinesterase (DEP) toxicity by donepezil plus scopolamine: a preliminary study
    • Janowsky D.S., Davish J.M., Oversreet D.H. Antagonism of anticholinesterase (DEP) toxicity by donepezil plus scopolamine: a preliminary study. Pharmacol Biochem Behav 2004, 77:337-343.
    • (2004) Pharmacol Biochem Behav , vol.77 , pp. 337-343
    • Janowsky, D.S.1    Davish, J.M.2    Oversreet, D.H.3
  • 44
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Jelhub J., Jacques P.F., Wilson P.W., Rush D., Rosenberg I.H. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993, 270:2693-2698.
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Jelhub, J.1    Jacques, P.F.2    Wilson, P.W.3    Rush, D.4    Rosenberg, I.H.5
  • 45
    • 30744450012 scopus 로고    scopus 로고
    • Elevated levels of Hcy compromise blood brain barrier integrity in mice
    • Kamath A.F., Chauhan A.K., Kisucka J., Dole V.S., Loscalzo J., Handy D.E., et al. Elevated levels of Hcy compromise blood brain barrier integrity in mice. Blood 2006, 107:591-593.
    • (2006) Blood , vol.107 , pp. 591-593
    • Kamath, A.F.1    Chauhan, A.K.2    Kisucka, J.3    Dole, V.S.4    Loscalzo, J.5    Handy, D.E.6
  • 46
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and Hcy impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of AD
    • Kruman I.I., Kumaravel T.S., Lohani A., Pedersen W.A., Cutler R.G., Kruman Y., et al. Folic acid deficiency and Hcy impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of AD. J Neurosci 2002, 22:1752-1762.
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3    Pedersen, W.A.4    Cutler, R.G.5    Kruman, Y.6
  • 50
    • 36949012725 scopus 로고    scopus 로고
    • The effect and mechanisms of mitochondrial nutrient α-lipoic acid on improving age associated mitochondrial and cognitive dysfunction: an overview
    • Liu J. The effect and mechanisms of mitochondrial nutrient α-lipoic acid on improving age associated mitochondrial and cognitive dysfunction: an overview. Neurochem Res 2008, 33:194-203.
    • (2008) Neurochem Res , vol.33 , pp. 194-203
    • Liu, J.1
  • 51
    • 71849104860 scopus 로고
    • Protein measurements with the folin phenol reagent
    • Lowry O.H., Rosebrough N.J., Farr A.L., Randal R.J. Protein measurements with the folin phenol reagent. J Biol 1951, 193:265-275.
    • (1951) J Biol , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randal, R.J.4
  • 52
    • 24344482909 scopus 로고    scopus 로고
    • Nanomolar aluminum induces proinflammatory and pro-apoptotic gene expression in human brain cells in primary culture
    • Lukiw W.J., Percy M.E., Kruck T.P. Nanomolar aluminum induces proinflammatory and pro-apoptotic gene expression in human brain cells in primary culture. J Inorg Biochem 2005, 99:1895-1898.
    • (2005) J Inorg Biochem , vol.99 , pp. 1895-1898
    • Lukiw, W.J.1    Percy, M.E.2    Kruck, T.P.3
  • 54
    • 21744441917 scopus 로고    scopus 로고
    • Parenteral antioxidant treatment preserves temporal discrimination following intrahippocampal aggregated Abeta (1-42) injections
    • McDaid D.G., Kim E.M., Reid R.E., Cleary J., Hare E.O. Parenteral antioxidant treatment preserves temporal discrimination following intrahippocampal aggregated Abeta (1-42) injections. Behav Pharmacol 2005, 16:237-242.
    • (2005) Behav Pharmacol , vol.16 , pp. 237-242
    • McDaid, D.G.1    Kim, E.M.2    Reid, R.E.3    Cleary, J.4    Hare, E.O.5
  • 55
    • 0346098195 scopus 로고    scopus 로고
    • Folate and vitamin E deficiency impair cognitive performance in mice subjected to oxidative stress: differential impact on normal mice and mice lacking apolipoprotein E
    • Mihalick S.M., Ortiz D., Kumar R., Rogers E., Shea T.B. Folate and vitamin E deficiency impair cognitive performance in mice subjected to oxidative stress: differential impact on normal mice and mice lacking apolipoprotein E. Neuromol Med 2004, 4:197-202.
    • (2004) Neuromol Med , vol.4 , pp. 197-202
    • Mihalick, S.M.1    Ortiz, D.2    Kumar, R.3    Rogers, E.4    Shea, T.B.5
  • 56
  • 59
    • 0035050096 scopus 로고    scopus 로고
    • Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey
    • Morris M.S., Jacques P.F., Rosenberg I.H., Selub J. Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey. Am J Clin Nutr 2001, 73:927-933.
    • (2001) Am J Clin Nutr , vol.73 , pp. 927-933
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3    Selub, J.4
  • 62
    • 57849101092 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors: a novel direction for Alzheimer's management
    • Nivsarkar M., Banejee A., Padh H. Cyclooxygenase inhibitors: a novel direction for Alzheimer's management. Pharmacol Rep 2008, 60:692-698.
    • (2008) Pharmacol Rep , vol.60 , pp. 692-698
    • Nivsarkar, M.1    Banejee, A.2    Padh, H.3
  • 64
    • 77952291438 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha mediated signaling in neuronal homeostasis and dysfunction
    • Park K.M., Bowers W.K. Tumor necrosis factor alpha mediated signaling in neuronal homeostasis and dysfunction. Cell Signal 2010, 22:977-983.
    • (2010) Cell Signal , vol.22 , pp. 977-983
    • Park, K.M.1    Bowers, W.K.2
  • 65
    • 77951621308 scopus 로고    scopus 로고
    • Involvement of phosphinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairment induced by beta amyloid 1-40 peptide in mice
    • Passos G.F., Figueiredo C.P., Prediger R.D., Silva K.A., Siqueira J.M., Duarte F.S., et al. Involvement of phosphinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairment induced by beta amyloid 1-40 peptide in mice. Brain Behav Immun 2010, 24:493-501.
    • (2010) Brain Behav Immun , vol.24 , pp. 493-501
    • Passos, G.F.1    Figueiredo, C.P.2    Prediger, R.D.3    Silva, K.A.4    Siqueira, J.M.5    Duarte, F.S.6
  • 66
    • 72049107236 scopus 로고    scopus 로고
    • Vitamin E use is associated with improved survival in an Alzheimer's disease cohort
    • Pavlik N.Y., Doody R.S., Rountree S.D., Darby E.J., Vitamin E use is associated with improved survival in an Alzheimer's disease cohort. Dement Geriatr Cogn Disord 2009, 28:536-540.
    • (2009) Dement Geriatr Cogn Disord , vol.28 , pp. 536-540
    • Pavlik, N.Y.1    Doody, R.S.2    Rountree, S.D.3    Darby, E.J.4
  • 67
    • 63349096757 scopus 로고    scopus 로고
    • Efficacy of a vitamin/nutriceutical formulation for moderate-stage to later stage Alzheimer's disease a placebo-controlled pilot study
    • Remington R., Chan A., Paskavitz J., Shea T.B. Efficacy of a vitamin/nutriceutical formulation for moderate-stage to later stage Alzheimer's disease a placebo-controlled pilot study. Am J Alzheimer's Dis Other Dement 2009, 24:27-33.
    • (2009) Am J Alzheimer's Dis Other Dement , vol.24 , pp. 27-33
    • Remington, R.1    Chan, A.2    Paskavitz, J.3    Shea, T.B.4
  • 68
    • 77950355906 scopus 로고    scopus 로고
    • Gene regulatory activity of alpha tocopherol
    • Rimback G., Moehring J., Huebbe P., Lodge J.K. Gene regulatory activity of alpha tocopherol. Molecules 2010, 15:1746-1761.
    • (2010) Molecules , vol.15 , pp. 1746-1761
    • Rimback, G.1    Moehring, J.2    Huebbe, P.3    Lodge, J.K.4
  • 69
    • 0037202852 scopus 로고    scopus 로고
    • The dementias
    • Ritchie K., Lovestone S. The dementias. Lancet 2002, 360:1759-1766.
    • (2002) Lancet , vol.360 , pp. 1759-1766
    • Ritchie, K.1    Lovestone, S.2
  • 70
    • 33750431618 scopus 로고    scopus 로고
    • Interaction of interleukin-1β with muscarinic acetylcholine receptor mediating signaling cascade in cholinergically differentiated SH-SY5Y cells
    • Schliebs R., Heidel K., Apelt J., Gniezdzinska M., Kirazov L., Szutowicz A. Interaction of interleukin-1β with muscarinic acetylcholine receptor mediating signaling cascade in cholinergically differentiated SH-SY5Y cells. Brain Res 2006, 1122:78-85.
    • (2006) Brain Res , vol.1122 , pp. 78-85
    • Schliebs, R.1    Heidel, K.2    Apelt, J.3    Gniezdzinska, M.4    Kirazov, L.5    Szutowicz, A.6
  • 71
    • 0035950225 scopus 로고    scopus 로고
    • Clearing the brain's amyloid cobwebs
    • Selkoe D.J. Clearing the brain's amyloid cobwebs. Neuron 2001, 32:177-180.
    • (2001) Neuron , vol.32 , pp. 177-180
    • Selkoe, D.J.1
  • 73
  • 74
    • 0036779577 scopus 로고    scopus 로고
    • Aluminum accumulation and membrane fluidity alteration in synaptosomes isolated from rat brain cortex following aluminum ingestion: effect of cholesterol
    • Silva V.S., Cordeiro J.M., Matos M.J., Oliveira C.R., Goncalves P.P. Aluminum accumulation and membrane fluidity alteration in synaptosomes isolated from rat brain cortex following aluminum ingestion: effect of cholesterol. Neurosci Res 2002, 44:181-193.
    • (2002) Neurosci Res , vol.44 , pp. 181-193
    • Silva, V.S.1    Cordeiro, J.M.2    Matos, M.J.3    Oliveira, C.R.4    Goncalves, P.P.5
  • 75
    • 0038342021 scopus 로고    scopus 로고
    • Brain energy metabolism is compromised by the metabolites accumulating in homocystinuria
    • Streck E.L., Delwing D., Tagliari B., Matte C., Wannmacher C.M., Wajner M., et al. Brain energy metabolism is compromised by the metabolites accumulating in homocystinuria. Neurochem Int 2003, 43:597-602.
    • (2003) Neurochem Int , vol.43 , pp. 597-602
    • Streck, E.L.1    Delwing, D.2    Tagliari, B.3    Matte, C.4    Wannmacher, C.M.5    Wajner, M.6
  • 76
    • 58649103550 scopus 로고    scopus 로고
    • Dietary supplementation with a combination of α-lipoic acid, acetyl-l-carnitine, glycerophospho-coline docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance
    • Suchy J., Chan A., Shea T.B. Dietary supplementation with a combination of α-lipoic acid, acetyl-l-carnitine, glycerophospho-coline docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. Nutr Res 2009, 29:70-74.
    • (2009) Nutr Res , vol.29 , pp. 70-74
    • Suchy, J.1    Chan, A.2    Shea, T.B.3
  • 77
    • 0027437376 scopus 로고
    • Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
    • Sun X.J., Crimmins D.L., Myers M.J., Miralpeix M., White M.F. Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol Cell Biol 1993, 13:7418-7428.
    • (1993) Mol Cell Biol , vol.13 , pp. 7418-7428
    • Sun, X.J.1    Crimmins, D.L.2    Myers, M.J.3    Miralpeix, M.4    White, M.F.5
  • 80
    • 57349088727 scopus 로고    scopus 로고
    • Minireview: mouse models of Alzheimer's dementia current concepts and new trends
    • Tores-Aleman I. Minireview: mouse models of Alzheimer's dementia current concepts and new trends. Endocrinology 2008, 149:5952-5957.
    • (2008) Endocrinology , vol.149 , pp. 5952-5957
    • Tores-Aleman, I.1
  • 82
    • 77950885346 scopus 로고    scopus 로고
    • Vitamin E forms in Alzheimer's disease, review of controversial and clinical experiences
    • Usoro V.O., Mousa S.A. Vitamin E forms in Alzheimer's disease, review of controversial and clinical experiences. Crit Rev Food Sci Nutr 2010, 50:414-419.
    • (2010) Crit Rev Food Sci Nutr , vol.50 , pp. 414-419
    • Usoro, V.O.1    Mousa, S.A.2
  • 83
    • 70350662460 scopus 로고    scopus 로고
    • Vascular factors and markers of inflammation in offspring with a parental history of late onset Alzheimer disease
    • Van-Exel E., Eikelenboom P., Comijs H., Frolich M., Smit J.H., Stek M.L., et al. Vascular factors and markers of inflammation in offspring with a parental history of late onset Alzheimer disease. Arch Gen Psychiatry 2009, 66:1263-1270.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1263-1270
    • Van-Exel, E.1    Eikelenboom, P.2    Comijs, H.3    Frolich, M.4    Smit, J.H.5    Stek, M.L.6
  • 85
    • 70350033993 scopus 로고    scopus 로고
    • APP expression, distribution and accumulation are altered by aluminum in rodent model for Alzheimer's disease
    • Walton J.R., Wang M.X. APP expression, distribution and accumulation are altered by aluminum in rodent model for Alzheimer's disease. J Inorg Biochem 2009, 103:1548-1554.
    • (2009) J Inorg Biochem , vol.103 , pp. 1548-1554
    • Walton, J.R.1    Wang, M.X.2
  • 86
    • 34548190489 scopus 로고    scopus 로고
    • An aluminum based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A a hyperphosphorylated tau, and granulovacuolar degeneration
    • Walton J.R. An aluminum based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A a hyperphosphorylated tau, and granulovacuolar degeneration. J Inorg Biochem 2007, 101:1275-1284.
    • (2007) J Inorg Biochem , vol.101 , pp. 1275-1284
    • Walton, J.R.1
  • 87
    • 71049182361 scopus 로고    scopus 로고
    • Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease
    • Walton J.R. Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease. Neurotoxicology 2009, 30:1059-1069.
    • (2009) Neurotoxicology , vol.30 , pp. 1059-1069
    • Walton, J.R.1
  • 88
    • 11144357815 scopus 로고    scopus 로고
    • Activation of methionine synthase by insulin like growth factor 1 and dopamine: a target for neurodevelopmental toxins and thimerosal
    • Waly M., Olteanu H., Banerjee R., Choi S.W., Mason J.B. Activation of methionine synthase by insulin like growth factor 1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry 2004, 9:358-370.
    • (2004) Mol Psychiatry , vol.9 , pp. 358-370
    • Waly, M.1    Olteanu, H.2    Banerjee, R.3    Choi, S.W.4    Mason, J.B.5
  • 89
    • 0642375802 scopus 로고    scopus 로고
    • + ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death
    • + ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death. Biochem Pharmacol 2003, 66:1601-1609.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1601-1609
    • Yu, S.P.1
  • 90
    • 65349162724 scopus 로고    scopus 로고
    • Hyperhomocysteinemia increases β amyloid by enhancing expression of γ-secretase and phosphorylation of amyloid precursor protein in rat brain
    • Zhang C.E., Wei W., Liu Y.H., Peng J.H., Tian Q., Liu G.P., et al. Hyperhomocysteinemia increases β amyloid by enhancing expression of γ-secretase and phosphorylation of amyloid precursor protein in rat brain. Am J Pathol 2009, 174:1481-1491.
    • (2009) Am J Pathol , vol.174 , pp. 1481-1491
    • Zhang, C.E.1    Wei, W.2    Liu, Y.H.3    Peng, J.H.4    Tian, Q.5    Liu, G.P.6
  • 91


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.