메뉴 건너뛰기




Volumn 50, Issue 5, 2010, Pages 414-419

Vitamin e forms in Alzheimer's disease: A review of controversial and clinical experiences

Author keywords

Alpha tocopherol; Antioxidants; Delta tocopherol; Gammatocopherol; Neurodegenerative disease; Oxidative stress; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT;

EID: 77950885346     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408390802304222     Document Type: Review
Times cited : (49)

References (48)
  • 1
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames, B. N., Shigenaga, M. K. and Hagen, T. M. (1993). Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci. 90(17): 7915-7922.
    • (1993) Proc Natl Acad Sci , vol.90 , Issue.17 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 2
    • 33644908499 scopus 로고    scopus 로고
    • Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina
    • Aydemir, O., Celebi, S., Yilmaz, T., Yekeler, H. and Kukner, A. S. (2004). Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina. Int Ophthalmol. 25(5-6):283-289.
    • (2004) Int Ophthalmol , vol.25 , Issue.5-6 , pp. 283-289
    • Aydemir, O.1    Celebi, S.2    Yilmaz, T.3    Yekeler, H.4    Kukner, A.S.5
  • 3
    • 0022656693 scopus 로고
    • Comparison of plasma alpha and gamma tocopherol levels following chronic oral administration of either all-rac-alpha-tocopheryl acetate or RRR-alpha-tocopheryl acetate in normal adult male subjects
    • Baker, H., Handelman, G. J., Short, S., Machlin, L. J., Bhagavan, H. N., Dratz, E. A. and Frank, O. (1986). Comparison of plasma alpha and gamma tocopherol levels following chronic oral administration of either all-rac-alpha-tocopheryl acetate or RRR-alpha-tocopheryl acetate in normal adult male subjects. Am J Clin Nutr. 43(3):382-387.
    • (1986) Am J Clin Nutr , vol.43 , Issue.3 , pp. 382-387
    • Baker, H.1    Handelman, G.J.2    Short, S.3    Machlin, L.J.4    Bhagavan, H.N.5    Dratz, E.A.6    Frank, O.7
  • 4
    • 0020580167 scopus 로고
    • Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?
    • Burton, G. W., Joyce, A. and Ingold, K. U. (1983). Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes? Arch Biochem Biophys. 221(1):281-290.
    • (1983) Arch Biochem Biophys , vol.221 , Issue.1 , pp. 281-290
    • Burton, G.W.1    Joyce, A.2    Ingold, K.U.3
  • 5
    • 0035988588 scopus 로고    scopus 로고
    • Vitamin E and neurodegenerative disorders associated with oxidative stress
    • Butterfield, D. A., Castegna, A., Drake, J., Scapagnini, G. and Calabrese, V. (2002). Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutr Neurosci. 5(4):229-239.
    • (2002) Nutr Neurosci , vol.5 , Issue.4 , pp. 229-239
    • Butterfield, D.A.1    Castegna, A.2    Drake, J.3    Scapagnini, G.4    Calabrese, V.5
  • 6
    • 1542377619 scopus 로고    scopus 로고
    • Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress
    • Canevari, L., Abramov, A. Y. and Duchen, M. R. (2004). Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress. Neurochem Res. 29(3):637-650.
    • (2004) Neurochem Res , vol.29 , Issue.3 , pp. 637-650
    • Canevari, L.1    Abramov, A.Y.2    Duchen, M.R.3
  • 7
    • 0030992539 scopus 로고    scopus 로고
    • Gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: Physiological implications
    • Christen, S., Woodall, A. A., Shigenaga, M. K., Southwell-Keely, P. T., Duncan, M. W. and Ames, B. N. (1997). gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications. Proc Natl Acad Sci. 94(7):3217-3222.
    • (1997) Proc Natl Acad Sci , vol.94 , Issue.7 , pp. 3217-3222
    • Christen, S.1    Woodall, A.A.2    Shigenaga, M.K.3    Southwell-Keely, P.T.4    Duncan, M.W.5    Ames, B.N.6
  • 8
    • 33644860047 scopus 로고    scopus 로고
    • Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes
    • Clarke, M. W., Ward, N. C., Wu, J. H., Hodgson, J. M., Puddey, I. B. and Croft, K. D. (2006). Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes. Am J Clin Nutr. 83(1):95-102.
    • (2006) Am J Clin Nutr , vol.83 , Issue.1 , pp. 95-102
    • Clarke, M.W.1    Ward, N.C.2    Wu, J.H.3    Hodgson, J.M.4    Puddey, I.B.5    Croft, K.D.6
  • 10
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J. T. and Puttfarcken, P. (1993). Oxidative stress, glutamate, and neurodegenerative disorders. Science. 262(5134):689-695.
    • (1993) Science , vol.262 , Issue.5134 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 11
    • 0033497509 scopus 로고    scopus 로고
    • Impact of diets with corn oil or olive/sunflower oils on DNA damage in healthy young men
    • Elmadfa, I. and Park, E. (1999). Impact of diets with corn oil or olive/sunflower oils on DNA damage in healthy young men. Eur J Nutr. 38(6):286-292.
    • (1999) Eur J Nutr , vol.38 , Issue.6 , pp. 286-292
    • Elmadfa, I.1    Park, E.2
  • 13
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • Evans, P. H. (1993). Free radicals in brain metabolism and pathology. Br Med Bull. 49(3):577-587.
    • (1993) Br Med Bull , vol.49 , Issue.3 , pp. 577-587
    • Evans, P.H.1
  • 14
    • 0036751954 scopus 로고    scopus 로고
    • Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
    • Floyd, R. A. and Hensley, K. (2002). Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging. 23(5):795-807.
    • (2002) Neurobiol Aging , vol.23 , Issue.5 , pp. 795-807
    • Floyd, R.A.1    Hensley, K.2
  • 17
    • 0032823769 scopus 로고    scopus 로고
    • Antioxidant defence mechanisms: From the beginning to the end (of the beginning)
    • Halliwell, B. (1999). Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Radic Res. 31(4):261-272.
    • (1999) Free Radic Res , vol.31 , Issue.4 , pp. 261-272
    • Halliwell, B.1
  • 18
    • 0028181883 scopus 로고
    • Human adipose alpha-tocopherol and gamma-tocopherol kinetics during and after 1 y of alpha-tocopherol supplementation
    • Handelman, G. J., Epstein, W. L., Peerson, J., Spiegelman, D., Machlin, L. J. and Dratz, E. A. (1994). Human adipose alpha-tocopherol and gamma-tocopherol kinetics during and after 1 y of alpha-tocopherol supplementation. Am J Clin Nutr. 59(5):1025-1032.
    • (1994) Am J Clin Nutr , vol.59 , Issue.5 , pp. 1025-1032
    • Handelman, G.J.1    Epstein, W.L.2    Peerson, J.3    Spiegelman, D.4    Machlin, L.J.5    Dratz, E.A.6
  • 19
    • 0022083255 scopus 로고
    • Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans
    • Handelman, G. J., Machlin, L. J., Fitch, K., Weiter, J. J. and Dratz, E. A. (1985). Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. J Nutr. 115(6):807-813.
    • (1985) J Nutr , vol.115 , Issue.6 , pp. 807-813
    • Handelman, G.J.1    Machlin, L.J.2    Fitch, K.3    Weiter, J.J.4    Dratz, E.A.5
  • 21
    • 0037442025 scopus 로고    scopus 로고
    • Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer
    • Huang, H. Y., Alberg, A. J., Norkus, E. P., Hoffman, S. C., Comstock, G. W. and Helzlsouer, K. J. (2003). Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer. Am J Epidemiol. 157(4):335-344.
    • (2003) Am J Epidemiol , vol.157 , Issue.4 , pp. 335-344
    • Huang, H.Y.1    Alberg, A.J.2    Norkus, E.P.3    Hoffman, S.C.4    Comstock, G.W.5    Helzlsouer, K.J.6
  • 22
    • 0141528825 scopus 로고    scopus 로고
    • Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans
    • Huang, H. Y. and Appel, L. J. (2003). Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans. J Nutr. 133(10):3137-3140.
    • (2003) J Nutr , vol.133 , Issue.10 , pp. 3137-3140
    • Huang, H.Y.1    Appel, L.J.2
  • 23
    • 0028059308 scopus 로고
    • Oxidative damage in neurodegenerative disease
    • Jenner, P. (1994). Oxidative damage in neurodegenerative disease. Lancet. 344(8925):796-798.
    • (1994) Lancet , vol.344 , Issue.8925 , pp. 796-798
    • Jenner, P.1
  • 24
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion S36-28
    • Jenner, P. (2003). Oxidative stress in Parkinson's disease. Ann Neurol. 53 Suppl 3: S26-36; discussion S36-28.
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 25
    • 0034633629 scopus 로고    scopus 로고
    • Gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells
    • Jiang, Q., Elson-Schwab, I., Courtemanche, C. and Ames, B. N. (2000). gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc Natl Acad Sci. 97(21):11494-11499.
    • (2000) Proc Natl Acad Sci , vol.97 , Issue.21 , pp. 11494-11499
    • Jiang, Q.1    Elson-Schwab, I.2    Courtemanche, C.3    Ames, B.N.4
  • 26
    • 0030015296 scopus 로고    scopus 로고
    • The chemistry and antioxidant properties of tocopherols and tocotrienols
    • Kamal-Eldin, A. and Appelqvist, L. A. (1996). The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids. 31(7):671-701.
    • (1996) Lipids , vol.31 , Issue.7 , pp. 671-701
    • Kamal-Eldin, A.1    Appelqvist, L.A.2
  • 27
    • 0031031920 scopus 로고    scopus 로고
    • Reactive oxygen species and the neurodegenerative disorders
    • Knight, J. A. (1997). Reactive oxygen species and the neurodegenerative disorders. Ann Clin Lab Sci. 27(1):11-25.
    • (1997) Ann Clin Lab Sci , vol.27 , Issue.1 , pp. 11-25
    • Knight, J.A.1
  • 28
    • 0035113436 scopus 로고    scopus 로고
    • Alpha- and gamma-tocotrienols are metabolized to carboxyethyl- hydroxychroman derivatives and excreted in human urine
    • Lodge, J. K., Ridlington, J., Leonard, S., Vaule, H. and Traber, M. G. (2001). Alpha- and gamma-tocotrienols are metabolized to carboxyethyl- hydroxychroman derivatives and excreted in human urine. Lipids. 36(1):43-48.
    • (2001) Lipids , vol.36 , Issue.1 , pp. 43-48
    • Lodge, J.K.1    Ridlington, J.2    Leonard, S.3    Vaule, H.4    Traber, M.G.5
  • 29
    • 0032872050 scopus 로고    scopus 로고
    • Effect of vitamin E intake on levels of vitamins E and C in the central nervous system and peripheral tissues: Implications for health recommendations
    • Martin, A., Janigian, D., Shukitt-Hale, B., Prior, R. L. and Joseph, J. A. (1999). Effect of vitamin E intake on levels of vitamins E and C in the central nervous system and peripheral tissues: implications for health recommendations. Brain Res. 845(1):50-59.
    • (1999) Brain Res , vol.845 , Issue.1 , pp. 50-59
    • Martin, A.1    Janigian, D.2    Shukitt-Hale, B.3    Prior, R.L.4    Joseph, J.A.5
  • 30
    • 0033872034 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells
    • McIntyre, B. S., Briski, K. P., Gapor, A. and Sylvester, P. W. (2000). Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells. Proc Soc Exp Biol Med. 224(4):292-301.
    • (2000) Proc Soc Exp Biol Med , vol.224 , Issue.4 , pp. 292-301
    • McIntyre, B.S.1    Briski, K.P.2    Gapor, A.3    Sylvester, P.W.4
  • 31
  • 35
    • 0032953285 scopus 로고    scopus 로고
    • Vitamin E, alpha- and gamma-tocopherol, and prostate cancer
    • Moyad, M. A., Brumfield, S. K. and Pienta, K. J. (1999). Vitamin E, alpha- and gamma-tocopherol, and prostate cancer. Semin Urol Oncol. 17(2):85-90.
    • (1999) Semin Urol Oncol , vol.17 , Issue.2 , pp. 85-90
    • Moyad, M.A.1    Brumfield, S.K.2    Pienta, K.J.3
  • 37
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: The cholesterol connection
    • Puglielli, L., Tanzi, R. E. and Kovacs, D. M. (2003). Alzheimer's disease: the cholesterol connection. Nat Neurosci. 6(4):345-351.
    • (2003) Nat Neurosci , vol.6 , Issue.4 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 40
    • 18344389020 scopus 로고    scopus 로고
    • Dietary vitamin E modulates differential gene expression in the rat hippocampus: Potential implications for its neuroprotective properties
    • Rota, C., Rimbach, G., Minihane, A. M., Stoecklin, E. and Barella, L. (2005). Dietary vitamin E modulates differential gene expression in the rat hippocampus: potential implications for its neuroprotective properties. Nutr Neurosci. 8(1):21-29.
    • (2005) Nutr Neurosci , vol.8 , Issue.1 , pp. 21-29
    • Rota, C.1    Rimbach, G.2    Minihane, A.M.3    Stoecklin, E.4    Barella, L.5
  • 41
    • 0012023188 scopus 로고    scopus 로고
    • Differential effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis
    • Saldeen, T., Li, D. and Mehta, J. L. (1999). Differential effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis. J Am Coll Cardiol. 34(4):1208-1215.
    • (1999) J Am Coll Cardiol , vol.34 , Issue.4 , pp. 1208-1215
    • Saldeen, T.1    Li, D.2    Mehta, J.L.3
  • 43
    • 13444293174 scopus 로고    scopus 로고
    • Defining molecular targets to prevent Alzheimer disease
    • Selkoe, D. J. (2005). Defining molecular targets to prevent Alzheimer disease. Arch Neurol. 62(2):192-195.
    • (2005) Arch Neurol , vol.62 , Issue.2 , pp. 192-195
    • Selkoe, D.J.1
  • 44
    • 35848965901 scopus 로고    scopus 로고
    • Biological redox systems and oxidative stress
    • Sies, H. (2007). Biological redox systems and oxidative stress. Cell Mol Life Sci. 64(17):2181-2188.
    • (2007) Cell Mol Life Sci , vol.64 , Issue.17 , pp. 2181-2188
    • Sies, H.1
  • 46
    • 0034573291 scopus 로고    scopus 로고
    • Piecing together Alzheimer's
    • St George-Hyslop, P. H. (2000). Piecing together Alzheimer's. Sci Am. 283(6):76-83.
    • (2000) Sci Am , vol.283 , Issue.6 , pp. 76-83
    • George-Hyslop St., P.H.1
  • 47
    • 4444358685 scopus 로고    scopus 로고
    • Gamma-tocopherol-an underestimated vitamin?
    • Wagner, K. H., Kamal-Eldin, A. and Elmadfa, I. (2004). Gamma-tocopherol-an underestimated vitamin? Ann Nutr Metab. 48(3):169-188.
    • (2004) Ann Nutr Metab , vol.48 , Issue.3 , pp. 169-188
    • Wagner, K.H.1    Kamal-Eldin, A.2    Elmadfa, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.