Involvement of phosphoinositide 3-kinase γ in the neuro-inflammatory response and cognitive impairments induced by β-amyloid 1-40 peptide in mice

Brain, Behavior, and Immunity

Volumn 24, Issue 3, 2010, Pages 493-501

  Passos, Giselle F ^a   Figueiredo, Cláudia P ^a   Prediger, Rui D S ^a   Silva, Kathryn A B S ^a   Siqueira, Jarbas M ^a   Duarte, Filipe S ^a   Leal, Paulo C ^a   Medeiros, Rodrigo ^a   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Amyloid; Alzheimer's disease; AS605240; Astrocyte; Brain; Cognitive decline; Cytokine; Inflammation; Microglia; Phosphoinositide 3 kinase

Indexed keywords

5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; 5 [5 (4 FLUORO 2 HYDROXYPHENYL)FURFURYLIDENE] 2,4 THIAZOLIDINEDIONE; AMYLOID BETA PROTEIN[1-40]; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SCOPOLAMINE; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN DISEASE; CELL ACTIVATION; CELL MIGRATION; CHEMOTAXIS; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVATION; HIPPOCAMPUS; IC 50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC POTENTIAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL SURVIVAL; CHEMOTAXIS, LEUKOCYTE; COGNITION; CYCLOOXYGENASE 2; ENZYME INHIBITORS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; ISOENZYMES; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; NEURITIS; NEUROGLIA; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-AKT; SYNAPSES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77951621308     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.12.003     Document Type: Article

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