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Volumn 39, Issue 4, 2012, Pages 473-485

Gene signatures in the management of hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CDKL2 PROTEIN; CTNNB1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; GENOMIC DNA; GENOMIC RNA; GLUL PROTEIN; GLUTATHIONE TRANSFERASE P1; HIST1H3G PROTEIN; LECT2 PROTEIN; LGR5 PROTEIN; PEPTIDES AND PROTEINS; PROTEIN P53; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; SECRETED FRIZZLED RELATED PROTEIN 1; SORAFENIB; STEAP4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN; ZNF154 PROTEIN;

EID: 84864455290     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2012.05.003     Document Type: Conference Paper
Times cited : (58)

References (123)
  • 1
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • L.A. Garraway, H.R. Widlund, M.A. Rubin Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma Nature 436 2005 117 122
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1    Widlund, H.R.2    Rubin, M.A.3
  • 2
    • 78650026375 scopus 로고    scopus 로고
    • ALK inhibition for non-small cell lung cancer: From discovery to therapy in record time
    • D.E. Gerber, J.D. Minna ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time Cancer Cell 18 2010 548 551
    • (2010) Cancer Cell , vol.18 , pp. 548-551
    • Gerber, D.E.1    Minna, J.D.2
  • 3
    • 79955433548 scopus 로고    scopus 로고
    • Targeted therapies for hepatocellular carcinoma
    • A. Villanueva, J.M. Llovet Targeted therapies for hepatocellular carcinoma Gastroenterology 140 2011 1410 1426
    • (2011) Gastroenterology , vol.140 , pp. 1410-1426
    • Villanueva, A.1    Llovet, J.M.2
  • 5
    • 77957552077 scopus 로고    scopus 로고
    • New strategies in hepatocellular carcinoma: Genomic prognostic markers
    • A. Villanueva, Y. Hoshida, S. Toffanin New strategies in hepatocellular carcinoma: genomic prognostic markers Clin Cancer Res 16 2010 4688 4694
    • (2010) Clin Cancer Res , vol.16 , pp. 4688-4694
    • Villanueva, A.1    Hoshida, Y.2    Toffanin, S.3
  • 6
    • 79957789708 scopus 로고    scopus 로고
    • Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses
    • J.P. Ioannidis, O.A. Panagiotou Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses JAMA 305 2011 2200 2210
    • (2011) JAMA , vol.305 , pp. 2200-2210
    • Ioannidis, J.P.1    Panagiotou, O.A.2
  • 7
    • 13444249852 scopus 로고    scopus 로고
    • Prediction of cancer outcome with microarrays: A multiple random validation strategy
    • S. Michiels, S. Koscielny, C. Hill Prediction of cancer outcome with microarrays: a multiple random validation strategy Lancet 365 2005 488 492
    • (2005) Lancet , vol.365 , pp. 488-492
    • Michiels, S.1    Koscielny, S.2    Hill, C.3
  • 8
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • T.J. Lynch, D.W. Bell, R. Sordella Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib N Engl J Med 350 2004 2129 2139
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 9
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • D. Ge, J. Fellay, A.J. Thompson Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance Nature 461 2009 399 401
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 10
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • E.E. Schadt Molecular networks as sensors and drivers of common human diseases Nature 461 2009 218 223
    • (2009) Nature , vol.461 , pp. 218-223
    • Schadt, E.E.1
  • 11
    • 41649114164 scopus 로고    scopus 로고
    • Enabling personalized cancer medicine through analysis of gene-expression patterns
    • L.J. van't Veer, R. Bernards Enabling personalized cancer medicine through analysis of gene-expression patterns Nature 452 2008 564 570
    • (2008) Nature , vol.452 , pp. 564-570
    • Van'T Veer, L.J.1    Bernards, R.2
  • 12
    • 84856753045 scopus 로고    scopus 로고
    • The genetic basis for cancer treatment decisions
    • J.E. Dancey, P.L. Bedard, N. Onetto, T.J. Hudson The genetic basis for cancer treatment decisions Cell 148 2012 409 420
    • (2012) Cell , vol.148 , pp. 409-420
    • Dancey, J.E.1    Bedard, P.L.2    Onetto, N.3    Hudson, T.J.4
  • 13
    • 78649508797 scopus 로고    scopus 로고
    • Nearest template prediction: A single-sample-based flexible class prediction with confidence assessment
    • Y. Hoshida Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment PLoS One 5 2010 e15543
    • (2010) PLoS One , vol.5 , pp. 15543
    • Hoshida, Y.1
  • 14
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • A. Subramanian, P. Tamayo, V.K. Mootha Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc Natl Acad Sci U S A 102 2005 15545 15550
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 15
    • 39149123547 scopus 로고    scopus 로고
    • Clinical application of the 70-gene profile: The MINDACT trial
    • F. Cardoso, L. Van't Veer, E. Rutgers Clinical application of the 70-gene profile: the MINDACT trial J Clin Oncol 26 2008 729 735
    • (2008) J Clin Oncol , vol.26 , pp. 729-735
    • Cardoso, F.1    Van'T Veer, L.2    Rutgers, E.3
  • 16
    • 39149113165 scopus 로고    scopus 로고
    • Development of the 21-gene assay and its application in clinical practice and clinical trials
    • J.A. Sparano, S. Paik Development of the 21-gene assay and its application in clinical practice and clinical trials J Clin Oncol 26 2008 721 728
    • (2008) J Clin Oncol , vol.26 , pp. 721-728
    • Sparano, J.A.1    Paik, S.2
  • 17
    • 79952438796 scopus 로고    scopus 로고
    • Genetics: An 18-gene signature (ColoPrint) for colon cancer prognosis
    • I.B. Tan, P. Tan Genetics: an 18-gene signature (ColoPrint) for colon cancer prognosis Nat Rev Clin Oncol 8 2011 131 133
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 131-133
    • Tan, I.B.1    Tan, P.2
  • 18
    • 33846978784 scopus 로고    scopus 로고
    • Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting
    • A. Dupuy, R.M. Simon Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting J Natl Cancer Inst 99 2007 147 157
    • (2007) J Natl Cancer Inst , vol.99 , pp. 147-157
    • Dupuy, A.1    Simon, R.M.2
  • 19
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • J. Lamb, E.D. Crawford, D. Peck The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease Science 313 2006 1929 1935
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3
  • 20
    • 79955401037 scopus 로고    scopus 로고
    • Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
    • e2
    • A. Villanueva, Y. Hoshida, C. Battiston Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma Gastroenterology 140 2011 1501 1512 e2
    • (2011) Gastroenterology , vol.140 , pp. 1501-1512
    • Villanueva, A.1    Hoshida, Y.2    Battiston, C.3
  • 21
    • 33746910265 scopus 로고    scopus 로고
    • Concordance among gene-expression-based predictors for breast cancer
    • C. Fan, D.S. Oh, L. Wessels Concordance among gene-expression-based predictors for breast cancer N Engl J Med 355 2006 560 569
    • (2006) N Engl J Med , vol.355 , pp. 560-569
    • Fan, C.1    Oh, D.S.2    Wessels, L.3
  • 22
    • 82755192534 scopus 로고    scopus 로고
    • Improving validation practices in "omics" research
    • J.P. Ioannidis, M.J. Khoury Improving validation practices in "omics" research Science 334 2011 1230 1232
    • (2011) Science , vol.334 , pp. 1230-1232
    • Ioannidis, J.P.1    Khoury, M.J.2
  • 23
    • 33745641883 scopus 로고    scopus 로고
    • Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer
    • N.L. Henry, D.F. Hayes Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer Oncologist 11 2006 541 552
    • (2006) Oncologist , vol.11 , pp. 541-552
    • Henry, N.L.1    Hayes, D.F.2
  • 24
    • 23844534811 scopus 로고    scopus 로고
    • Reporting recommendations for tumor marker prognostic studies (REMARK)
    • L.M. McShane, D.G. Altman, W. Sauerbrei Reporting recommendations for tumor marker prognostic studies (REMARK) J Natl Cancer Inst 97 2005 1180 1184
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1180-1184
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 25
    • 70449420123 scopus 로고    scopus 로고
    • Use of archived specimens in evaluation of prognostic and predictive biomarkers
    • R.M. Simon, S. Paik, D.F. Hayes Use of archived specimens in evaluation of prognostic and predictive biomarkers J Natl Cancer Inst 101 2009 1446 1452
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1446-1452
    • Simon, R.M.1    Paik, S.2    Hayes, D.F.3
  • 26
    • 40449100030 scopus 로고    scopus 로고
    • Direct multiplexed measurement of gene expression with color-coded probe pairs
    • G.K. Geiss, R.E. Bumgarner, B. Birditt Direct multiplexed measurement of gene expression with color-coded probe pairs Nat Biotechnol 26 2008 317 325
    • (2008) Nat Biotechnol , vol.26 , pp. 317-325
    • Geiss, G.K.1    Bumgarner, R.E.2    Birditt, B.3
  • 27
    • 79952259417 scopus 로고    scopus 로고
    • Genome-sequencing anniversary First steps on a long road
    • E. Schadt Genome-sequencing anniversary First steps on a long road Science 331 2011 691
    • (2011) Science , vol.331 , pp. 691
    • Schadt, E.1
  • 28
    • 78650328715 scopus 로고    scopus 로고
    • The road from discovery to clinical diagnostics: Lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers
    • Z. Zhang, D.W. Chan The road from discovery to clinical diagnostics: lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers Cancer Epidemiol Biomarkers Prev 19 2010 2995 2999
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 2995-2999
    • Zhang, Z.1    Chan, D.W.2
  • 29
    • 70349739285 scopus 로고    scopus 로고
    • Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
    • Y. Hoshida, S.M. Nijman, M. Kobayashi Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma Cancer Res 69 2009 7385 7392
    • (2009) Cancer Res , vol.69 , pp. 7385-7392
    • Hoshida, Y.1    Nijman, S.M.2    Kobayashi, M.3
  • 30
    • 53049086329 scopus 로고    scopus 로고
    • Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
    • D.Y. Chiang, A. Villanueva, Y. Hoshida Focal gains of VEGFA and molecular classification of hepatocellular carcinoma Cancer Res 68 2008 6779 6788
    • (2008) Cancer Res , vol.68 , pp. 6779-6788
    • Chiang, D.Y.1    Villanueva, A.2    Hoshida, Y.3
  • 31
    • 33846846541 scopus 로고    scopus 로고
    • Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas
    • J. Zucman-Rossi, S. Benhamouche, C. Godard Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas Oncogene 26 2007 774 780
    • (2007) Oncogene , vol.26 , pp. 774-780
    • Zucman-Rossi, J.1    Benhamouche, S.2    Godard, C.3
  • 32
    • 46249085489 scopus 로고    scopus 로고
    • Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
    • C. Coulouarn, V.M. Factor, S.S. Thorgeirsson Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer Hepatology 47 2008 2059 2067
    • (2008) Hepatology , vol.47 , pp. 2059-2067
    • Coulouarn, C.1    Factor, V.M.2    Thorgeirsson, S.S.3
  • 33
    • 84856191525 scopus 로고    scopus 로고
    • Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers
    • B.D. White, A.J. Chien, D.W. Dawson Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers Gastroenterology 142 2012 219 232
    • (2012) Gastroenterology , vol.142 , pp. 219-232
    • White, B.D.1    Chien, A.J.2    Dawson, D.W.3
  • 34
    • 57749191711 scopus 로고    scopus 로고
    • Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: A retrospective, exploratory analysis
    • V. Mazzaferro, J.M. Llovet, R. Miceli Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis Lancet Oncol 10 2009 35 43
    • (2009) Lancet Oncol , vol.10 , pp. 35-43
    • Mazzaferro, V.1    Llovet, J.M.2    Miceli, R.3
  • 35
    • 69349099400 scopus 로고    scopus 로고
    • A system of classifying microvascular invasion to predict outcome after resection in patients with hepatocellular carcinoma
    • S. Roayaie, I.N. Blume, S.N. Thung A system of classifying microvascular invasion to predict outcome after resection in patients with hepatocellular carcinoma Gastroenterology 137 2009 850 855
    • (2009) Gastroenterology , vol.137 , pp. 850-855
    • Roayaie, S.1    Blume, I.N.2    Thung, S.N.3
  • 36
    • 80054717602 scopus 로고    scopus 로고
    • Gene-expression signature of vascular invasion in hepatocellular carcinoma
    • B. Minguez, Y. Hoshida, A. Villanueva Gene-expression signature of vascular invasion in hepatocellular carcinoma J Hepatol 55 2011 1325 1331
    • (2011) J Hepatol , vol.55 , pp. 1325-1331
    • Minguez, B.1    Hoshida, Y.2    Villanueva, A.3
  • 37
    • 57349090407 scopus 로고    scopus 로고
    • Gene expression in fixed tissues and outcome in hepatocellular carcinoma
    • Y. Hoshida, A. Villanueva, M. Kobayashi Gene expression in fixed tissues and outcome in hepatocellular carcinoma N Engl J Med 359 2008 1995 2004
    • (2008) N Engl J Med , vol.359 , pp. 1995-2004
    • Hoshida, Y.1    Villanueva, A.2    Kobayashi, M.3
  • 38
    • 33747029250 scopus 로고    scopus 로고
    • Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
    • A. Budhu, M. Forgues, Q.H. Ye Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment Cancer Cell 10 2006 99 111
    • (2006) Cancer Cell , vol.10 , pp. 99-111
    • Budhu, A.1    Forgues, M.2    Ye, Q.H.3
  • 39
    • 77951652404 scopus 로고    scopus 로고
    • Gene-expression signature predicts outcome of liver cirrhosis
    • Y. Hoshida, A. Villanueva, A. Sangiovanni Gene-expression signature predicts outcome of liver cirrhosis Hepatology 50 2009 312A
    • (2009) Hepatology , vol.50
    • Hoshida, Y.1    Villanueva, A.2    Sangiovanni, A.3
  • 40
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • H.B. El-Serag Hepatocellular carcinoma N Engl J Med 365 2011 1118 1127
    • (2011) N Engl J Med , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 42
    • 84864428936 scopus 로고    scopus 로고
    • Prevention of hepatocellular carcinoma: Potential targets, experimental models, and clinical challenges
    • [In press]
    • Y. Hoshida, B.C. Fuchs, K.K. Tanabe Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges Curr Cancer Drug Targets 2012 [In press]
    • (2012) Curr Cancer Drug Targets
    • Hoshida, Y.1    Fuchs, B.C.2    Tanabe, K.K.3
  • 43
    • 79952231921 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma: An update
    • J. Bruix, M. Sherman Management of hepatocellular carcinoma: an update Hepatology 53 2011 1020 1022
    • (2011) Hepatology , vol.53 , pp. 1020-1022
    • Bruix, J.1    Sherman, M.2
  • 45
    • 0037308463 scopus 로고    scopus 로고
    • Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy
    • H. Imamura, Y. Matsuyama, E. Tanaka Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy J Hepatol 38 2003 200 207
    • (2003) J Hepatol , vol.38 , pp. 200-207
    • Imamura, H.1    Matsuyama, Y.2    Tanaka, E.3
  • 46
    • 78650361904 scopus 로고    scopus 로고
    • A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
    • S. Roessler, H.L. Jia, A. Budhu A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients Cancer Res 70 2010 10202 10212
    • (2010) Cancer Res , vol.70 , pp. 10202-10212
    • Roessler, S.1    Jia, H.L.2    Budhu, A.3
  • 47
    • 58149151278 scopus 로고    scopus 로고
    • The use of genomics in clinical trial design
    • R. Simon The use of genomics in clinical trial design Clin Cancer Res 14 2008 5984 5993
    • (2008) Clin Cancer Res , vol.14 , pp. 5984-5993
    • Simon, R.1
  • 48
    • 84859441677 scopus 로고    scopus 로고
    • Drug development and clinical trials-the path to an approved cancer drug
    • E.H. Rubin, D.G. Gilliland Drug development and clinical trials-the path to an approved cancer drug Nat Rev Clin Oncol 9 2012 215 222
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 215-222
    • Rubin, E.H.1    Gilliland, D.G.2
  • 49
    • 84858658381 scopus 로고    scopus 로고
    • EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma
    • EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma J Hepatol 56 2012 908 943
    • (2012) J Hepatol , vol.56 , pp. 908-943
  • 50
    • 42449156691 scopus 로고    scopus 로고
    • Identification of noninvasive imaging surrogates for brain tumor gene-expression modules
    • M. Diehn, C. Nardini, D.S. Wang Identification of noninvasive imaging surrogates for brain tumor gene-expression modules Proc Natl Acad Sci U S A 105 2008 5213 5218
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5213-5218
    • Diehn, M.1    Nardini, C.2    Wang, D.S.3
  • 51
    • 34250697544 scopus 로고    scopus 로고
    • Radiogenomic analysis to identify imaging phenotypes associated with drug response gene expression programs in hepatocellular carcinoma
    • M.D. Kuo, J. Gollub, C.B. Sirlin Radiogenomic analysis to identify imaging phenotypes associated with drug response gene expression programs in hepatocellular carcinoma J Vasc Interv Radiol 18 2007 821 831
    • (2007) J Vasc Interv Radiol , vol.18 , pp. 821-831
    • Kuo, M.D.1    Gollub, J.2    Sirlin, C.B.3
  • 52
    • 34250195010 scopus 로고    scopus 로고
    • Decoding global gene expression programs in liver cancer by noninvasive imaging
    • E. Segal, C.B. Sirlin, C. Ooi Decoding global gene expression programs in liver cancer by noninvasive imaging Nat Biotechnol 25 2007 675 680
    • (2007) Nat Biotechnol , vol.25 , pp. 675-680
    • Segal, E.1    Sirlin, C.B.2    Ooi, C.3
  • 53
    • 0035985214 scopus 로고    scopus 로고
    • Gene expression patterns in human liver cancers
    • X. Chen, S.T. Cheung, S. So Gene expression patterns in human liver cancers Mol Biol Cell 13 2002 1929 1939
    • (2002) Mol Biol Cell , vol.13 , pp. 1929-1939
    • Chen, X.1    Cheung, S.T.2    So, S.3
  • 54
    • 52149102033 scopus 로고    scopus 로고
    • Methylation of tumor associated genes in tissue and plasma samples from liver disease patients
    • H. Chang, B. Yi, L. Li Methylation of tumor associated genes in tissue and plasma samples from liver disease patients Exp Mol Pathol 85 2008 96 100
    • (2008) Exp Mol Pathol , vol.85 , pp. 96-100
    • Chang, H.1    Yi, B.2    Li, L.3
  • 55
    • 79957507207 scopus 로고    scopus 로고
    • Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma
    • D. Hua, Y. Hu, Y.Y. Wu Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma Exp Mol Pathol 91 2011 455 460
    • (2011) Exp Mol Pathol , vol.91 , pp. 455-460
    • Hua, D.1    Hu, Y.2    Wu, Y.Y.3
  • 56
    • 80053515231 scopus 로고    scopus 로고
    • Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma
    • Z.H. Huang, Y. Hu, D. Hua Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma Exp Mol Pathol 91 2011 702 707
    • (2011) Exp Mol Pathol , vol.91 , pp. 702-707
    • Huang, Z.H.1    Hu, Y.2    Hua, D.3
  • 57
    • 74749099086 scopus 로고    scopus 로고
    • Concordance of DNA methylation pattern in plasma and tumor DNA of Egyptian hepatocellular carcinoma patients
    • P. Iyer, A.R. Zekri, C.W. Hung Concordance of DNA methylation pattern in plasma and tumor DNA of Egyptian hepatocellular carcinoma patients Exp Mol Pathol 88 2010 107 111
    • (2010) Exp Mol Pathol , vol.88 , pp. 107-111
    • Iyer, P.1    Zekri, A.R.2    Hung, C.W.3
  • 58
    • 82555195665 scopus 로고    scopus 로고
    • CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis
    • J.B. Liu, Y.X. Zhang, S.H. Zhou CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis World J Gastroenterol 17 2011 4718 4724
    • (2011) World J Gastroenterol , vol.17 , pp. 4718-4724
    • Liu, J.B.1    Zhang, Y.X.2    Zhou, S.H.3
  • 59
    • 33646091508 scopus 로고    scopus 로고
    • Detection of aberrant promoter methylation of GSTP1 in the tumor and serum of Chinese human primary hepatocellular carcinoma patients
    • J. Wang, Y. Qin, B. Li, Z. Sun, B. Yang Detection of aberrant promoter methylation of GSTP1 in the tumor and serum of Chinese human primary hepatocellular carcinoma patients Clin Biochem 39 2006 344 348
    • (2006) Clin Biochem , vol.39 , pp. 344-348
    • Wang, J.1    Qin, Y.2    Li, B.3    Sun, Z.4    Yang, B.5
  • 60
    • 17044387017 scopus 로고    scopus 로고
    • High frequency of promoter hypermethylation of RASSF1A in tumor and plasma of patients with hepatocellular carcinoma
    • W. Yeo, N. Wong, W.L. Wong, P.B. Lai, S. Zhong, P.J. Johnson High frequency of promoter hypermethylation of RASSF1A in tumor and plasma of patients with hepatocellular carcinoma Liver Int 25 2005 266 272
    • (2005) Liver Int , vol.25 , pp. 266-272
    • Yeo, W.1    Wong, N.2    Wong, W.L.3    Lai, P.B.4    Zhong, S.5    Johnson, P.J.6
  • 61
    • 34247895661 scopus 로고    scopus 로고
    • Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA
    • Y.J. Zhang, H.C. Wu, J. Shen Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA Clin Cancer Res 13 2007 2378 2384
    • (2007) Clin Cancer Res , vol.13 , pp. 2378-2384
    • Zhang, Y.J.1    Wu, H.C.2    Shen, J.3
  • 62
    • 84861572881 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiles in hepatocellular carcinoma
    • J. Shen, S. Wang, Y.J. Zhang Genome-wide DNA methylation profiles in hepatocellular carcinoma Hepatology 55 2012 1799 1808
    • (2012) Hepatology , vol.55 , pp. 1799-1808
    • Shen, J.1    Wang, S.2    Zhang, Y.J.3
  • 63
    • 78649972032 scopus 로고    scopus 로고
    • Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma
    • L.M. Li, Z.B. Hu, Z.X. Zhou Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma Cancer Res 70 2010 9798 9807
    • (2010) Cancer Res , vol.70 , pp. 9798-9807
    • Li, L.M.1    Hu, Z.B.2    Zhou, Z.X.3
  • 64
  • 65
    • 78651417662 scopus 로고    scopus 로고
    • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis
    • J. Xu, C. Wu, X. Che Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis Mol Carcinog 50 2011 136 142
    • (2011) Mol Carcinog , vol.50 , pp. 136-142
    • Xu, J.1    Wu, C.2    Che, X.3
  • 66
    • 80052008851 scopus 로고    scopus 로고
    • Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease
    • S. Cermelli, A. Ruggieri, J.A. Marrero, G.N. Ioannou, L. Beretta Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease PLoS One 6 2011 e23937
    • (2011) PLoS One , vol.6 , pp. 23937
    • Cermelli, S.1    Ruggieri, A.2    Marrero, J.A.3    Ioannou, G.N.4    Beretta, L.5
  • 67
    • 82955217238 scopus 로고    scopus 로고
    • Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection
    • P. Qi, S.Q. Cheng, H. Wang, N. Li, Y.F. Chen, C.F. Gao Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection PLoS One 6 2011 e28486
    • (2011) PLoS One , vol.6 , pp. 28486
    • Qi, P.1    Cheng, S.Q.2    Wang, H.3    Li, N.4    Chen, Y.F.5    Gao, C.F.6
  • 68
    • 63149121152 scopus 로고    scopus 로고
    • Circulating microRNAs, potential biomarkers for drug-induced liver injury
    • K. Wang, S. Zhang, B. Marzolf Circulating microRNAs, potential biomarkers for drug-induced liver injury Proc Natl Acad Sci U S A 106 2009 4402 4407
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4402-4407
    • Wang, K.1    Zhang, S.2    Marzolf, B.3
  • 69
    • 84555202717 scopus 로고    scopus 로고
    • Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma
    • J. Zhou, L. Yu, X. Gao Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma J Clin Oncol 29 2011 4781 4788
    • (2011) J Clin Oncol , vol.29 , pp. 4781-4788
    • Zhou, J.1    Yu, L.2    Gao, X.3
  • 70
    • 77953192081 scopus 로고    scopus 로고
    • Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer
    • Z. Huang, D. Huang, S. Ni, Z. Peng, W. Sheng, X. Du Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer Int J Cancer 127 2011 118 126
    • (2011) Int J Cancer , vol.127 , pp. 118-126
    • Huang, Z.1    Huang, D.2    Ni, S.3    Peng, Z.4    Sheng, W.5    Du, X.6
  • 71
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: A potential marker for colorectal cancer screening
    • E.K. Ng, W.W. Chong, H. Jin Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening Gut 58 2009 1375 1381
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3
  • 72
    • 57649091633 scopus 로고    scopus 로고
    • The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform
    • K.E. Resnick, H. Alder, J.P. Hagan, D.L. Richardson, C.M. Croce, D.E. Cohn The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform Gynecol Oncol 112 2009 55 59
    • (2009) Gynecol Oncol , vol.112 , pp. 55-59
    • Resnick, K.E.1    Alder, H.2    Hagan, J.P.3    Richardson, D.L.4    Croce, C.M.5    Cohn, D.E.6
  • 73
    • 79951771769 scopus 로고    scopus 로고
    • MiR-1254 and miR-574-5p: Serum-based microRNA biomarkers for early-stage non-small cell lung cancer
    • K.M. Foss, C. Sima, D. Ugolini, M. Neri, K.E. Allen, G.J. Weiss miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer J Thorac Oncol 6 2011 482 488
    • (2011) J Thorac Oncol , vol.6 , pp. 482-488
    • Foss, K.M.1    Sima, C.2    Ugolini, D.3    Neri, M.4    Allen, K.E.5    Weiss, G.J.6
  • 74
    • 84863415612 scopus 로고    scopus 로고
    • Serum microRNA biomarkers for detection of non-small cell lung cancer
    • P.T. Hennessey, T. Sanford, A. Choudhary Serum microRNA biomarkers for detection of non-small cell lung cancer PLoS One 7 2012 e32307
    • (2012) PLoS One , vol.7 , pp. 32307
    • Hennessey, P.T.1    Sanford, T.2    Choudhary, A.3
  • 75
    • 79953178293 scopus 로고    scopus 로고
    • Plasma microRNAs as potential biomarkers for non-small-cell lung cancer
    • J. Shen, N.W. Todd, H. Zhang Plasma microRNAs as potential biomarkers for non-small-cell lung cancer Lab Invest 91 2011 579 587
    • (2011) Lab Invest , vol.91 , pp. 579-587
    • Shen, J.1    Todd, N.W.2    Zhang, H.3
  • 76
    • 0000110505 scopus 로고
    • A case of cancer in which cells similar to those in the tumours were seen in the blood after death
    • T.R. Ashworth A case of cancer in which cells similar to those in the tumours were seen in the blood after death Aust Med J 14 1869 146 147
    • (1869) Aust Med J , vol.14 , pp. 146-147
    • Ashworth, T.R.1
  • 77
    • 4143094988 scopus 로고    scopus 로고
    • Circulating tumor cells, disease progression, and survival in metastatic breast cancer
    • M. Cristofanilli, G.T. Budd, M.J. Ellis Circulating tumor cells, disease progression, and survival in metastatic breast cancer N Engl J Med 351 2004 781 791
    • (2004) N Engl J Med , vol.351 , pp. 781-791
    • Cristofanilli, M.1    Budd, G.T.2    Ellis, M.J.3
  • 78
    • 70449713638 scopus 로고    scopus 로고
    • Circulating tumor cells: A useful predictor of treatment efficacy in metastatic breast cancer
    • M.C. Liu, P.G. Shields, R.D. Warren Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer J Clin Oncol 27 2009 5153 5159
    • (2009) J Clin Oncol , vol.27 , pp. 5153-5159
    • Liu, M.C.1    Shields, P.G.2    Warren, R.D.3
  • 79
    • 79955016306 scopus 로고    scopus 로고
    • Circulating tumor cells: Not all detected cells are bad and not all bad cells are detected
    • M.S. Wicha, D.F. Hayes Circulating tumor cells: not all detected cells are bad and not all bad cells are detected J Clin Oncol 29 2011 1508 1511
    • (2011) J Clin Oncol , vol.29 , pp. 1508-1511
    • Wicha, M.S.1    Hayes, D.F.2
  • 80
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • S. Nagrath, L.V. Sequist, S. Maheswaran Isolation of rare circulating tumour cells in cancer patients by microchip technology Nature 450 2007 1235 1239
    • (2007) Nature , vol.450 , pp. 1235-1239
    • Nagrath, S.1    Sequist, L.V.2    Maheswaran, S.3
  • 81
    • 78649872067 scopus 로고    scopus 로고
    • Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
    • S.L. Stott, C.H. Hsu, D.I. Tsukrov Isolation of circulating tumor cells using a microvortex-generating herringbone-chip Proc Natl Acad Sci U S A 107 2010 18392 18397
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 18392-18397
    • Stott, S.L.1    Hsu, C.H.2    Tsukrov, D.I.3
  • 82
    • 79957892094 scopus 로고    scopus 로고
    • Isolation of circulating tumor cells in patients with hepatocellular carcinoma using a novel cell separation strategy
    • W. Xu, L. Cao, L. Chen Isolation of circulating tumor cells in patients with hepatocellular carcinoma using a novel cell separation strategy Clin Cancer Res 17 2011 3783 3793
    • (2011) Clin Cancer Res , vol.17 , pp. 3783-3793
    • Xu, W.1    Cao, L.2    Chen, L.3
  • 83
    • 84863229772 scopus 로고    scopus 로고
    • Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm
    • Y. Hou, L. Song, P. Zhu Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm Cell 148 2012 873 885
    • (2012) Cell , vol.148 , pp. 873-885
    • Hou, Y.1    Song, L.2    Zhu, P.3
  • 84
    • 40449099255 scopus 로고    scopus 로고
    • EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
    • T. Yamashita, M. Forgues, W. Wang EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma Cancer Res 68 2008 1451 1461
    • (2008) Cancer Res , vol.68 , pp. 1451-1461
    • Yamashita, T.1    Forgues, M.2    Wang, W.3
  • 85
    • 60449087921 scopus 로고    scopus 로고
    • EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
    • T. Yamashita, J. Ji, A. Budhu EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features Gastroenterology 136 2009 1012 1024
    • (2009) Gastroenterology , vol.136 , pp. 1012-1024
    • Yamashita, T.1    Ji, J.2    Budhu, A.3
  • 86
    • 33645742425 scopus 로고    scopus 로고
    • A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
    • J.S. Lee, J. Heo, L. Libbrecht A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells Nat Med 12 2006 410 416
    • (2006) Nat Med , vol.12 , pp. 410-416
    • Lee, J.S.1    Heo, J.2    Libbrecht, L.3
  • 87
    • 77955849040 scopus 로고    scopus 로고
    • Genomic tracing of the elusive liver cancer ancestor
    • H. Cornella, A. Villanueva Genomic tracing of the elusive liver cancer ancestor J Hepatol 53 2010 578 579
    • (2010) J Hepatol , vol.53 , pp. 578-579
    • Cornella, H.1    Villanueva, A.2
  • 88
    • 12444255162 scopus 로고    scopus 로고
    • Sensitive and specific detection of circulating cancer cells in patients with hepatocellular carcinoma; Detection of human telomerase reverse transcriptase messenger RNA after immunomagnetic separation
    • N. Waguri, T. Suda, M. Nomoto Sensitive and specific detection of circulating cancer cells in patients with hepatocellular carcinoma; detection of human telomerase reverse transcriptase messenger RNA after immunomagnetic separation Clin Cancer Res 9 2003 3004 3011
    • (2003) Clin Cancer Res , vol.9 , pp. 3004-3011
    • Waguri, N.1    Suda, T.2    Nomoto, M.3
  • 89
    • 12144287967 scopus 로고    scopus 로고
    • Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer
    • G. Vona, L. Estepa, C. Beroud Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer Hepatology 39 2004 792 797
    • (2004) Hepatology , vol.39 , pp. 792-797
    • Vona, G.1    Estepa, L.2    Beroud, C.3
  • 90
    • 38549139140 scopus 로고    scopus 로고
    • + cancer stem cells in human liver cancer
    • + cancer stem cells in human liver cancer Cancer Cell 13 2008 153 166
    • (2008) Cancer Cell , vol.13 , pp. 153-166
    • Yang, Z.F.1    Ho, D.W.2    Ng, M.N.3
  • 91
    • 4544273428 scopus 로고    scopus 로고
    • Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
    • J.S. Lee, I.S. Chu, J. Heo Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling Hepatology 403 2004 667 676
    • (2004) Hepatology , vol.403 , pp. 667-676
    • Lee, J.S.1    Chu, I.S.2    Heo, J.3
  • 92
    • 33745220780 scopus 로고    scopus 로고
    • Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
    • P. Kaposi-Novak, J.S. Lee, L. Gomez-Quiroz, C. Coulouarn, V.M. Factor, S.S. Thorgeirsson Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype J Clin Invest 1166 2006 1582 1595
    • (2006) J Clin Invest , vol.1166 , pp. 1582-1595
    • Kaposi-Novak, P.1    Lee, J.S.2    Gomez-Quiroz, L.3    Coulouarn, C.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 93
    • 77950616980 scopus 로고    scopus 로고
    • Progenitor-derived hepatocellular carcinoma model in the rat
    • J.B. Andersen, R. Loi, A. Perra Progenitor-derived hepatocellular carcinoma model in the rat Hepatology 514 2010 1401 1409
    • (2010) Hepatology , vol.514 , pp. 1401-1409
    • Andersen, J.B.1    Loi, R.2    Perra, A.3
  • 94
    • 80052031109 scopus 로고    scopus 로고
    • Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways
    • J.U. Marquardt, C. Raggi, J.B. Andersen Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways Hepatology 543 2011 1031 1042
    • (2011) Hepatology , vol.543 , pp. 1031-1042
    • Marquardt, J.U.1    Raggi, C.2    Andersen, J.B.3
  • 95
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • S. Boyault, D.S. Rickman, A. de Reynies Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets Hepatology 451 2007 42 52
    • (2007) Hepatology , vol.451 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    De Reynies, A.3
  • 96
    • 0037391756 scopus 로고    scopus 로고
    • Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
    • Q.H. Ye, L.X. Qin, M. Forgues Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning Nat Med 94 2003 416 423
    • (2003) Nat Med , vol.94 , pp. 416-423
    • Ye, Q.H.1    Qin, L.X.2    Forgues, M.3
  • 97
    • 77951037177 scopus 로고    scopus 로고
    • Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma
    • H.G. Woo, J.H. Lee, J.H. Yoon Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma Cancer Res 708 2010 3034 3041
    • (2010) Cancer Res , vol.708 , pp. 3034-3041
    • Woo, H.G.1    Lee, J.H.2    Yoon, J.H.3
  • 98
    • 84862808163 scopus 로고    scopus 로고
    • Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma
    • S.M. Kim, S.H. Leem, I.S. Chu Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma Hepatology 555 2012 1443 1452
    • (2012) Hepatology , vol.555 , pp. 1443-1452
    • Kim, S.M.1    Leem, S.H.2    Chu, I.S.3
  • 99
    • 80052841535 scopus 로고    scopus 로고
    • Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma
    • I. Ivanovska, C. Zhang, A.M. Liu Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma PLoS One 69 2011 e24582
    • (2011) PLoS One , vol.69 , pp. 24582
    • Ivanovska, I.1    Zhang, C.2    Liu, A.M.3
  • 100
    • 84864980500 scopus 로고    scopus 로고
    • Integrated analysis of prognostic gene expression profiles from hepatitis B virus-positive hepatocellular carcinoma and adjacent liver tissue
    • 10.1245/s10434-011-1709-0
    • B.Y. Kim, K.S. Suh, J.G. Lee Integrated analysis of prognostic gene expression profiles from hepatitis B virus-positive hepatocellular carcinoma and adjacent liver tissue Ann Surg Oncol 2011 10.1245/s10434-011-1709-0
    • (2011) Ann Surg Oncol
    • Kim, B.Y.1    Suh, K.S.2    Lee, J.G.3
  • 101
    • 79960428190 scopus 로고    scopus 로고
    • Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma
    • Q. Gao, X.Y. Wang, S.J. Qiu Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma Cancer Sci 1028 2011 1522 1531
    • (2011) Cancer Sci , vol.1028 , pp. 1522-1531
    • Gao, Q.1    Wang, X.Y.2    Qiu, S.J.3
  • 102
    • 35948981211 scopus 로고    scopus 로고
    • Identification and validation of a novel gene signature associated with the recurrence of human hepatocellular carcinoma
    • S.M. Wang, L.L. Ooi, K.M. Hui Identification and validation of a novel gene signature associated with the recurrence of human hepatocellular carcinoma Clin Cancer Res 1321 2007 6275 6283
    • (2007) Clin Cancer Res , vol.1321 , pp. 6275-6283
    • Wang, S.M.1    Ooi, L.L.2    Hui, K.M.3
  • 103
    • 0037443891 scopus 로고    scopus 로고
    • Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection
    • 3619361
    • N. Iizuka, M. Oka, H. Yamada-Okabe Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection Lancet 3619361 2003 923 929
    • (2003) Lancet , pp. 923-929
    • Iizuka, N.1    Oka, M.2    Yamada-Okabe, H.3
  • 104
    • 4444286417 scopus 로고    scopus 로고
    • Molecular-based prediction of early recurrence in hepatocellular carcinoma
    • Y. Kurokawa, R. Matoba, I. Takemasa Molecular-based prediction of early recurrence in hepatocellular carcinoma J Hepatol 412 2004 284 291
    • (2004) J Hepatol , vol.412 , pp. 284-291
    • Kurokawa, Y.1    Matoba, R.2    Takemasa, I.3
  • 105
    • 42249087302 scopus 로고    scopus 로고
    • Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma
    • H.G. Woo, E.S. Park, J.H. Cheon Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma Clin Cancer Res 147 2008 2056 2064
    • (2008) Clin Cancer Res , vol.147 , pp. 2056-2064
    • Woo, H.G.1    Park, E.S.2    Cheon, J.H.3
  • 106
    • 61349127144 scopus 로고    scopus 로고
    • Molecular prediction of early recurrence after resection of hepatocellular carcinoma
    • S. Yoshioka, I. Takemasa, H. Nagano Molecular prediction of early recurrence after resection of hepatocellular carcinoma Eur J Cancer 455 2009 881 889
    • (2009) Eur J Cancer , vol.455 , pp. 881-889
    • Yoshioka, S.1    Takemasa, I.2    Nagano, H.3
  • 107
    • 33947204625 scopus 로고    scopus 로고
    • Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma
    • H.L. Jia, Q.H. Ye, L.X. Qin Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma Clin Cancer Res 134 2007 1133 1139
    • (2007) Clin Cancer Res , vol.134 , pp. 1133-1139
    • Jia, H.L.1    Ye, Q.H.2    Qin, L.X.3
  • 108
    • 33845790499 scopus 로고    scopus 로고
    • A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis
    • J.M. Llovet, Y. Chen, E. Wurmbach A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis Gastroenterology 1316 2006 1758 1767
    • (2006) Gastroenterology , vol.1316 , pp. 1758-1767
    • Llovet, J.M.1    Chen, Y.2    Wurmbach, E.3
  • 109
    • 38949184246 scopus 로고    scopus 로고
    • Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival
    • J. Jiang, Y. Gusev, I. Aderca Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival Clin Cancer Res 142 2008 419 427
    • (2008) Clin Cancer Res , vol.142 , pp. 419-427
    • Jiang, J.1    Gusev, Y.2    Aderca, I.3
  • 110
    • 40949087185 scopus 로고    scopus 로고
    • Identification of metastasis-related microRNAs in hepatocellular carcinoma
    • A. Budhu, H.L. Jia, M. Forgues Identification of metastasis-related microRNAs in hepatocellular carcinoma Hepatology 473 2008 897 907
    • (2008) Hepatology , vol.473 , pp. 897-907
    • Budhu, A.1    Jia, H.L.2    Forgues, M.3
  • 111
    • 79551507191 scopus 로고    scopus 로고
    • MicroRNA profile predicts recurrence after resection in patients with hepatocellular carcinoma within the Milan criteria
    • F. Sato, E. Hatano, K. Kitamura MicroRNA profile predicts recurrence after resection in patients with hepatocellular carcinoma within the Milan criteria PLoS One 61 2011 e16435
    • (2011) PLoS One , vol.61 , pp. 16435
    • Sato, F.1    Hatano, E.2    Kitamura, K.3
  • 112
    • 67649881121 scopus 로고    scopus 로고
    • Lin28 promotes transformation and is associated with advanced human malignancies
    • S.R. Viswanathan, J.T. Powers, W. Einhorn Lin28 promotes transformation and is associated with advanced human malignancies Nat Genet 417 2009 843 848
    • (2009) Nat Genet , vol.417 , pp. 843-848
    • Viswanathan, S.R.1    Powers, J.T.2    Einhorn, W.3
  • 113
    • 35648950024 scopus 로고    scopus 로고
    • Genetically distinct and clinically relevant classification of hepatocellular carcinoma: Putative therapeutic targets
    • H. Katoh, H. Ojima, A. Kokubu Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets Gastroenterology 1335 2007 1475 1486
    • (2007) Gastroenterology , vol.1335 , pp. 1475-1486
    • Katoh, H.1    Ojima, H.2    Kokubu, A.3
  • 114
    • 0034995765 scopus 로고    scopus 로고
    • Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis
    • P. Laurent-Puig, P. Legoix, O. Bluteau Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis Gastroenterology 1207 2001 1763 1773
    • (2001) Gastroenterology , vol.1207 , pp. 1763-1773
    • Laurent-Puig, P.1    Legoix, P.2    Bluteau, O.3
  • 115
    • 34848881905 scopus 로고    scopus 로고
    • Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma
    • D.F. Calvisi, S. Ladu, A. Gorden Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma J Clin Invest 1179 2007 2713 2722
    • (2007) J Clin Invest , vol.1179 , pp. 2713-2722
    • Calvisi, D.F.1    Ladu, S.2    Gorden, A.3
  • 116
    • 77954952259 scopus 로고    scopus 로고
    • CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage i hepatocellular carcinoma
    • B. Li, W. Liu, L. Wang CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma Ann Surg Oncol 177 2010 1917 1926
    • (2010) Ann Surg Oncol , vol.177 , pp. 1917-1926
    • Li, B.1    Liu, W.2    Wang, L.3
  • 117
    • 53349171172 scopus 로고    scopus 로고
    • Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas
    • W. Gao, Y. Kondo, L. Shen Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas Carcinogenesis 2910 2008 1901 1910
    • (2008) Carcinogenesis , vol.2910 , pp. 1901-1910
    • Gao, W.1    Kondo, Y.2    Shen, L.3
  • 118
    • 0035872493 scopus 로고    scopus 로고
    • Genome-wide hypomethylation in hepatocellular carcinogenesis
    • C.H. Lin, S.Y. Hsieh, I.S. Sheen Genome-wide hypomethylation in hepatocellular carcinogenesis Cancer Res 6110 2001 4238 4243
    • (2001) Cancer Res , vol.6110 , pp. 4238-4243
    • Lin, C.H.1    Hsieh, S.Y.2    Sheen, I.S.3
  • 119
    • 77957361278 scopus 로고    scopus 로고
    • Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
    • H. Hernandez-Vargas, M.P. Lambert, F. Le Calvez-Kelm Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors PLoS One 53 2010 e9749
    • (2010) PLoS One , vol.53 , pp. 9749
    • Hernandez-Vargas, H.1    Lambert, M.P.2    Le Calvez-Kelm, F.3
  • 120
    • 79956368802 scopus 로고    scopus 로고
    • Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma
    • R. Tao, J. Li, J. Xin Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma PLoS One 65 2011 e19862
    • (2011) PLoS One , vol.65 , pp. 19862
    • Tao, R.1    Li, J.2    Xin, J.3
  • 121
    • 0037094189 scopus 로고    scopus 로고
    • DNA methylation and environmental exposures in human hepatocellular carcinoma
    • L. Shen, N. Ahuja, Y. Shen DNA methylation and environmental exposures in human hepatocellular carcinoma J Natl Cancer Inst 9410 2002 755 761
    • (2002) J Natl Cancer Inst , vol.9410 , pp. 755-761
    • Shen, L.1    Ahuja, N.2    Shen, Y.3
  • 122
    • 33745225917 scopus 로고    scopus 로고
    • Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C virus-positive patients
    • M. Okamoto, T. Utsunomiya, S. Wakiyama Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C virus-positive patients Ann Surg Oncol 137 2006 947 954
    • (2006) Ann Surg Oncol , vol.137 , pp. 947-954
    • Okamoto, M.1    Utsunomiya, T.2    Wakiyama, S.3
  • 123
    • 77950670673 scopus 로고    scopus 로고
    • Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma
    • M. Tsuchiya, J.S. Parker, H. Kono, M. Matsuda, H. Fujii, I. Rusyn Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma Mol Cancer 9 2010 74
    • (2010) Mol Cancer , vol.9 , pp. 74
    • Tsuchiya, M.1    Parker, J.S.2    Kono, H.3    Matsuda, M.4    Fujii, H.5    Rusyn, I.6


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