A novel viral SOCS from infectious spleen and kidney necrosis virus: Interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Guo, Chang Jun ^a   Yang, Li Shi ^a   Zhang, Ying Fen ^a   Wu, Yan Yan ^a   Weng, Shao Ping ^a   Yu, Xiao Qiang ^b   He, Jian Guo ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; JANUS KINASE 1; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSIVE ELEMENT; ENZYME INHIBITION; FISH; GENE OVEREXPRESSION; HOST PATHOGEN INTERACTION; IN VITRO STUDY; INFECTIOUS SPLEEN AND KIDNEY NECROSIS VIRUS; INFECTIOUS SPLEEN AND KIDNEY NECROSIS VIRUS INFECTION; INTRACELLULAR SIGNALING; IRIDOVIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POINT MUTATION; PROMOTER REGION; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; UNINDEXED SEQUENCE; VIRUS IMMUNITY; VIRUS INFECTION; VIRUS PATHOGENESIS; ZOONOSIS;

AMINO ACID SEQUENCE; ANIMALS; COMPUTATIONAL BIOLOGY; GENES, REPORTER; HEP G2 CELLS; HUMANS; INTERFERON-ALPHA; JANUS KINASE 1; KIDNEY; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; POINT MUTATION; PROTEIN BINDING; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRAGER DUCK SPLEEN NECROSIS VIRUS; VIRAL PROTEINS;

INFECTIOUS SPLEEN AND KIDNEY NECROSIS VIRUS; IRIDOVIRIDAE; MEGALOCYTIVIRUS; VERTEBRATA;

EID: 84864195871     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041092     Document Type: Article

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