SOCS3 targets Siglec 7 for proteasomal degradation and blocks siglec 7-mediated responses

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 3418-3422

  Orr, Selinda J ^a   Morgan, Nuala M ^a   Buick, Richard J ^a   Boyd, Caroline R ^a   Elliott, Joanne ^a   Burrows, James F ^a   Jefferies, Caroline A ^b   Crocker, Paul R ^c   Johnston, James A ^a,d  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d Centre for Cancer Research and Cell Biology   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE-INDUCED PROLIFERATION; PROTEASOMAL DEGRADATION; SIALIC ACID;

BIODEGRADABILITY; BIOMEDICAL ENGINEERING; CELLS; ENZYME INHIBITION; IMMUNOLOGY;

PROTEINS;

PROTEASOME; PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 7; SUPPRESSOR OF CYTOKINE SIGNALING 3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; LECTIN; N ACETYLNEURAMINIC ACID; SIALIC ACID BINDING IG LIKE LECTIN; SIALIC ACID BINDING IG-LIKE LECTIN; SOCS3 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING; TYROSINE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL SURFACE; CROSS LINKING; IMMUNOPRECIPITATION; INFECTION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG ANTAGONISM; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CELL LINE; HUMANS; LECTINS; MICE; N-ACETYLNEURAMINIC ACID; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TYROSINE;

EID: 33947499837     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C600216200     Document Type: Article

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