메뉴 건너뛰기




Volumn , Issue MAY 2012, 2012, Pages

Modulation of iron metabolism in aging and in Alzheimer's disease: Relevance of the choroid plexus

Author keywords

Aging; Alzheimer's disease; Cerebrospinal fluid; Choroid plexus; Iron

Indexed keywords

IRON; TRANSFERRIN;

EID: 84863994297     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2012.00025     Document Type: Review
Times cited : (39)

References (102)
  • 2
    • 69749084874 scopus 로고    scopus 로고
    • Cytoplasmic gelsolin increases mitochondrial activity and reduces Abeta burden in a mouse model of Alzheimer's disease
    • Antequera, D., Vargas, T., Ugalde, C., Spuch, C., Molina, J. A., Ferrer, I., Bermejo-Pareja, F., and Carro, E. (2009). Cytoplasmic gelsolin increases mitochondrial activity and reduces Abeta burden in a mouse model of Alzheimer's disease. Neurobiol. Dis. 36, 42-50.
    • (2009) Neurobiol. Dis. , vol.36 , pp. 42-50
    • Antequera, D.1    Vargas, T.2    Ugalde, C.3    Spuch, C.4    Molina, J.A.5    Ferrer, I.6    Bermejo-Pareja, F.7    Carro, E.8
  • 6
    • 67449123256 scopus 로고    scopus 로고
    • Brain iron homeostasis and neurodegenerative disease
    • Benarroch, E. E. (2009). Brain iron homeostasis and neurodegenerative disease. Neurology 72, 1436-1440.
    • (2009) Neurology , vol.72 , pp. 1436-1440
    • Benarroch, E.E.1
  • 7
    • 67349276645 scopus 로고    scopus 로고
    • Amyloid precursor protein and alpha synu-clein translation, implications for iron and inflammation in neu-rodegenerative diseases
    • Cahill, C. M., Lahiri, D. K., Huang, X., and Rogers, J. T. (2009). Amyloid precursor protein and alpha synu-clein translation, implications for iron and inflammation in neu-rodegenerative diseases. Biochim. Biophys. Acta 1790, 615-628.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 615-628
    • Cahill, C.M.1    Lahiri, D.K.2    Huang, X.3    Rogers, J.T.4
  • 8
    • 78751580475 scopus 로고    scopus 로고
    • Iron and erythropoiesis: A dual relationship
    • Camaschella, C., and Pagani, A. (2011). Iron and erythropoiesis: a dual relationship. Int. J. Hematol. 93, 21-26.
    • (2011) Int. J. Hematol. , vol.93 , pp. 21-26
    • Camaschella, C.1    Pagani, A.2
  • 9
    • 28044466172 scopus 로고    scopus 로고
    • Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I
    • Carro, E., Spuch, C., Trejo, J. L., Antequera, D., and Torres-Aleman, I. (2005). Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I. J. Neurosci. 25, 10884-10893.
    • (2005) J. Neurosci. , vol.25 , pp. 10884-10893
    • Carro, E.1    Spuch, C.2    Trejo, J.L.3    Antequera, D.4    Torres-Aleman, I.5
  • 10
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease
    • Carro, E., and Torres-Aleman, I. (2004). The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease. Eur. J. Pharmacol. 490, 127-133.
    • (2004) Eur. J. Pharmacol. , vol.490 , pp. 127-133
    • Carro, E.1    Torres-Aleman, I.2
  • 11
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-beta levels
    • Carro, E., Trejo, J. L., Gomez-Isla, T., LeRoith, D., and Torres-Aleman, I. (2002). Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat. Med. 8, 1390-1397.
    • (2002) Nat. Med. , vol.8 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 12
    • 33748438509 scopus 로고    scopus 로고
    • Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: New cues into the human disease?
    • Carro, E., Trejo, J. L., Spuch, C., Bohl, D., Heard, J. M., and Torres-Aleman, I. (2006). Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease? Neurobiol. Aging 27, 1618-1631.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1618-1631
    • Carro, E.1    Trejo, J.L.2    Spuch, C.3    Bohl, D.4    Heard, J.M.5    Torres-Aleman, I.6
  • 14
    • 38649119160 scopus 로고    scopus 로고
    • Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
    • Chen, J., Buchanan, J. B., Sparkman, N. L., Godbout, J. P., Freund, G. G., and Johnson, R. W. (2008). Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain Behav. Immun. 22, 301-311.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 301-311
    • Chen, J.1    Buchanan, J.B.2    Sparkman, N.L.3    Godbout, J.P.4    Freund, G.G.5    Johnson, R.W.6
  • 15
    • 79955683626 scopus 로고    scopus 로고
    • Increased plasma levels of lipocalin 2 in mild cognitive impairment
    • Choi, J., Lee, H. W., and Suk, K. (2011). Increased plasma levels of lipocalin 2 in mild cognitive impairment. J. Neurol. Sci. 305, 28-33.
    • (2011) J. Neurol. Sci. , vol.305 , pp. 28-33
    • Choi, J.1    Lee, H.W.2    Suk, K.3
  • 16
    • 34347364708 scopus 로고    scopus 로고
    • Accelerated abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin)
    • Choi, S. H., Leight, S. N., Lee, V. M., Li, T., Wong, P. C., Johnson, J. A., Saraiva, M. J., and Sisodia, S. S. (2007). Accelerated abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). J. Neurosci. 27, 7006-7010.
    • (2007) J. Neurosci. , vol.27 , pp. 7006-7010
    • Choi, S.H.1    Leight, S.N.2    Lee, V.M.3    Li, T.4    Wong, P.C.5    Johnson, J.A.6    Saraiva, M.J.7    Sisodia, S.S.8
  • 17
    • 4444226451 scopus 로고    scopus 로고
    • Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis
    • Chua, A. C., Olynyk, J. K., Leedman, P. J., and Trinder, D. (2004). Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis. Blood 104, 1519-1525.
    • (2004) Blood , vol.104 , pp. 1519-1525
    • Chua, A.C.1    Olynyk, J.K.2    Leedman, P.J.3    Trinder, D.4
  • 19
    • 80051658907 scopus 로고    scopus 로고
    • Brain iron metabolism and its perturbation in neurological diseases
    • Crichton, R. R., Dexter, D. T., and Ward, R. J. (2011). Brain iron metabolism and its perturbation in neurological diseases. J. Neural. Transm. 118, 301-314.
    • (2011) J. Neural. Transm. , vol.118 , pp. 301-314
    • Crichton, R.R.1    Dexter, D.T.2    Ward, R.J.3
  • 20
    • 27644457417 scopus 로고    scopus 로고
    • The choroid plexus removes beta-amyloid from brain cerebrospinal fluid
    • Crossgrove, J. S., Li, G. J., and Zheng, W. (2005). The choroid plexus removes beta-amyloid from brain cerebrospinal fluid. Exp. Biol. Med. (Maywood) 230, 771-776.
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 771-776
    • Crossgrove, J.S.1    Li, G.J.2    Zheng, W.3
  • 21
    • 29244492306 scopus 로고    scopus 로고
    • A cell-surface receptor for lipocalin 24p3 selectively mediates apopto-sis and iron uptake
    • Devireddy, L. R., Gazin, C., Zhu, X., and Green, M. R. (2005). A cell-surface receptor for lipocalin 24p3 selectively mediates apopto-sis and iron uptake. Cell 123, 1293-1305.
    • (2005) Cell , vol.123 , pp. 1293-1305
    • Devireddy, L.R.1    Gazin, C.2    Zhu, X.3    Green, M.R.4
  • 22
    • 77953690176 scopus 로고    scopus 로고
    • A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production
    • Devireddy, L. R., Hart, D. O., Goetz, D. H., and Green, M. R. (2010). A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production. Cell 141, 1006-1017.
    • (2010) Cell , vol.141 , pp. 1006-1017
    • Devireddy, L.R.1    Hart, D.O.2    Goetz, D.H.3    Green, M.R.4
  • 23
    • 0022970287 scopus 로고
    • Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver
    • Dickson, P. W., Aldred, A. R., Marley, P. D., Bannister, D., and Schreiber, G. (1986). Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver. J. Biol. Chem. 261, 3475-3478.
    • (1986) J. Biol. Chem. , vol.261 , pp. 3475-3478
    • Dickson, P.W.1    Aldred, A.R.2    Marley, P.D.3    Bannister, D.4    Schreiber, G.5
  • 24
    • 76749088922 scopus 로고    scopus 로고
    • Possible involvement of transthyretin in hippocampal beta-amyloid burden and learning behaviors in a mouse model of Alzheimer's disease (TgCRND8)
    • Doggui, S., Brouillette, J., Chabot, J. G., Farso, M., and Quirion, R. (2010). Possible involvement of transthyretin in hippocampal beta-amyloid burden and learning behaviors in a mouse model of Alzheimer's disease (TgCRND8). Neurodegener. Dis. 7, 88-95.
    • (2010) Neurodegener. Dis. , vol.7 , pp. 88-95
    • Doggui, S.1    Brouillette, J.2    Chabot, J.G.3    Farso, M.4    Quirion, R.5
  • 25
    • 77953940704 scopus 로고    scopus 로고
    • Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics
    • Duce, J. A., and Bush, A. I. (2010). Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics. Prog. Neurobiol. 92, 1-18.
    • (2010) Prog. Neurobiol. , vol.92 , pp. 1-18
    • Duce, J.A.1    Bush, A.I.2
  • 27
    • 0037357190 scopus 로고    scopus 로고
    • Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures
    • Egana, J. T., Zambrano, C., Nunez, M. T., Gonzalez-Billault, C., and Maccioni, R. B. (2003). Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures. Biometals 16, 215-223.
    • (2003) Biometals , vol.16 , pp. 215-223
    • Egana, J.T.1    Zambrano, C.2    Nunez, M.T.3    Gonzalez-Billault, C.4    McCioni, R.B.5
  • 29
    • 73449115641 scopus 로고    scopus 로고
    • The blood-brain and the blood-cerebrospinal fluid barriers: Function and dysfunction
    • Engelhardt, B., and Sorokin, L. (2009). The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Semin. Immunopathol. 31, 497-511.
    • (2009) Semin. Immunopathol. , vol.31 , pp. 497-511
    • Engelhardt, B.1    Sorokin, L.2
  • 30
    • 0035153262 scopus 로고    scopus 로고
    • Involvement of the choroid plexus in central nervous system inflammation
    • Engelhardt, B., Wolburg-Buchholz, K., and Wolburg, H. (2001). Involvement of the choroid plexus in central nervous system inflammation. Microsc. Res. Tech. 52, 112-129.
    • (2001) Microsc. Res. Tech. , vol.52 , pp. 112-129
    • Engelhardt, B.1    Wolburg-Buchholz, K.2    Wolburg, H.3
  • 32
    • 29044438902 scopus 로고    scopus 로고
    • The crucial role of metal ions in neurodegeneration: The basis for a promising therapeutic strategy
    • Gaeta, A., and Hider, R. C. (2005). The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy. Br. J. Pharmacol. 146, 1041-1059.
    • (2005) Br. J. Pharmacol. , vol.146 , pp. 1041-1059
    • Gaeta, A.1    Hider, R.C.2
  • 33
    • 79955958017 scopus 로고    scopus 로고
    • Hepcidin and iron regulation, 10 years later
    • Ganz, T. (2011). Hepcidin and iron regulation, 10 years later. Blood 117, 4425-4433.
    • (2011) Blood , vol.117 , pp. 4425-4433
    • Ganz, T.1
  • 34
    • 79551583056 scopus 로고    scopus 로고
    • Hepcidin and disorders of iron metabolism
    • Ganz, T., and Nemeth, E. (2011). Hepcidin and disorders of iron metabolism. Annu. Rev. Med. 62, 347-360.
    • (2011) Annu. Rev. Med. , vol.62 , pp. 347-360
    • Ganz, T.1    Nemeth, E.2
  • 39
    • 40349112963 scopus 로고    scopus 로고
    • The blood-CSF barrier explained: When development is not immaturity
    • Johansson, P. A., Dziegielewska, K. M., Liddelow, S. A., and Saunders, N. R. (2008). The blood-CSF barrier explained: when development is not immaturity. Bioessays 30, 237-248.
    • (2008) Bioessays , vol.30 , pp. 237-248
    • Johansson, P.A.1    Dziegielewska, K.M.2    Liddelow, S.A.3    Saunders, N.R.4
  • 40
    • 65449120792 scopus 로고    scopus 로고
    • Iron behaving badly: Inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
    • Kell, D. B. (2009). Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMCMed. Genomics 2, 2.
    • (2009) BMCMed. Genomics , vol.2 , pp. 2
    • Kell, D.B.1
  • 41
    • 0027256664 scopus 로고
    • Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase
    • Kjeldsen, L., Johnsen, A. H., Sengelov, H., and Borregaard, N. (1993). Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268, 10425-10432.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10425-10432
    • Kjeldsen, L.1    Johnsen, A.H.2    Sengelov, H.3    Borregaard, N.4
  • 43
    • 83755181397 scopus 로고    scopus 로고
    • Lipocalin-2 Is a chemokine inducer in the central nervous system: Role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration
    • Lee, S., Kim, J. H., Seo, J. W., Han, H. S., Lee, W. H., Mori, K., Nakao, K., Barasch, J., and Suk, K. (2011). Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration. J. Biol. Chem. 286, 43855-43870.
    • (2011) J. Biol. Chem. , vol.286 , pp. 43855-43870
    • Lee, S.1    Kim, J.H.2    Seo, J.W.3    Han, H.S.4    Lee, W.H.5    Mori, K.6    Nakao, K.7    Barasch, J.8    Suk, K.9
  • 44
    • 58149400146 scopus 로고    scopus 로고
    • Lipocalin-2 is an autocrine mediator of reactive astrocytosis
    • Lee, S., Park, J. Y., Lee, W. H., Kim, H., Park, H. C., Mori, K., and Suk, K. (2009). Lipocalin-2 is an autocrine mediator of reactive astrocytosis. J. Neurosci. 29, 234-249.
    • (2009) J. Neurosci. , vol.29 , pp. 234-249
    • Lee, S.1    Park, J.Y.2    Lee, W.H.3    Kim, H.4    Park, H.C.5    Mori, K.6    Suk, K.7
  • 45
    • 13844307889 scopus 로고    scopus 로고
    • Regulation of hepcidin transcription by interleukin-1 and interleukin-6
    • Lee, P., Peng, H., Gelbart, T., Wang, L., and Beutler, E. (2005). Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc. Natl. Acad. Sci. U.S.A. 102, 1906-1910.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 1906-1910
    • Lee, P.1    Peng, H.2    Gelbart, T.3    Wang, L.4    Beutler, E.5
  • 47
    • 78951481093 scopus 로고    scopus 로고
    • Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease
    • Leskovjan, A. C., Kretlow, A., Lanzirotti, A., Barrea, R., Vogt, S., and Miller, L. M. (2011). Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease. Neuroimage 55, 32-38.
    • (2011) Neuroimage , vol.55 , pp. 32-38
    • Leskovjan, A.C.1    Kretlow, A.2    Lanzirotti, A.3    Barrea, R.4    Vogt, S.5    Miller, L.M.6
  • 48
    • 0034652323 scopus 로고    scopus 로고
    • Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: Implications for beta-amyloid formation
    • Li, M. D., Kane, J. K., Matta, S. G., Blaner, W. S., and Sharp, B. M. (2000). Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: implications for beta-amyloid formation. J. Neurosci. 20, 1318-1323.
    • (2000) J. Neurosci. , vol.20 , pp. 1318-1323
    • Li, M.D.1    Kane, J.K.2    Matta, S.G.3    Blaner, W.S.4    Sharp, B.M.5
  • 50
    • 0029115795 scopus 로고
    • Identification of anew acute phase protein
    • Liu, Q., and Nilsen-Hamilton, M. (1995). Identification of anew acute phase protein. J. Biol. Chem. 270, 22565-22570.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22565-22570
    • Liu, Q.1    Nilsen-Hamilton, M.2
  • 51
    • 33747436236 scopus 로고    scopus 로고
    • Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells
    • Marco, S., and Skaper, S. D. (2006). Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells. Neurosci. Lett. 401, 219-224.
    • (2006) Neurosci. Lett. , vol.401 , pp. 219-224
    • Marco, S.1    Skaper, S.D.2
  • 59
    • 33748090285 scopus 로고    scopus 로고
    • Brain capillary endothelial cells mediate iron transport into the brain by segregating iron from transferrin without the involvement of divalent metal transporter 1
    • Moos, T., Skjoerringe, T., Gosk, S., and Morgan, E. H. (2006). Brain capillary endothelial cells mediate iron transport into the brain by segregating iron from transferrin without the involvement of divalent metal transporter 1. J. Neurochem. 98, 1946-1958.
    • (2006) J. Neurochem. , vol.98 , pp. 1946-1958
    • Moos, T.1    Skjoerringe, T.2    Gosk, S.3    Morgan, E.H.4
  • 60
    • 0034184526 scopus 로고    scopus 로고
    • Cellular distribution of ferric iron, ferritin, transferrin and divalent metal transporter 1 (DMT1) in substantia nigra and basal ganglia of normal and beta2-microglobulin deficient mouse brain
    • Moos, T., Trinder, D., and Morgan, E. H. (2000). Cellular distribution of ferric iron, ferritin, transferrin and divalent metal transporter 1 (DMT1) in substantia nigra and basal ganglia of normal and beta2-microglobulin deficient mouse brain. Cell. Mol. Biol. (Noisy-le-grand) 46, 549-561.
    • (2000) Cell. Mol. Biol. (Noisy-le-grand) , vol.46 , pp. 549-561
    • Moos, T.1    Trinder, D.2    Morgan, E.H.3
  • 61
    • 0026689961 scopus 로고
    • Uptake and distribution of iron and transferrin in the adult rat brain
    • Morris, C. M., Keith, A. B., Edwardson, J. A., and Pullen, R. G. (1992). Uptake and distribution of iron and transferrin in the adult rat brain. J. Neurochem. 59, 300-306.
    • (1992) J. Neurochem. , vol.59 , pp. 300-306
    • Morris, C.M.1    Keith, A.B.2    Edwardson, J.A.3    Pullen, R.G.4
  • 62
    • 81055126115 scopus 로고    scopus 로고
    • Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation
    • Mucha, M., Skrzypiec, A. E., Schiavon, E., Attwood, B. K., Kucerova, E., and Pawlak, R. (2011). Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation. Proc. Natl. Acad. Sci. U.S.A. 108, 18436-18441.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 18436-18441
    • Mucha, M.1    Skrzypiec, A.E.2    Schiavon, E.3    Attwood, B.K.4    Kucerova, E.5    Pawlak, R.6
  • 63
    • 0022446170 scopus 로고
    • High-resolution proton magnetic resonance analysis of human cerebrospinal fluid
    • Petroff, O. A., Yu, R. K., and Ogino, T. (1986). High-resolution proton magnetic resonance analysis of human cerebrospinal fluid. J. Neurochem. 47, 1270-1276.
    • (1986) J. Neurochem. , vol.47 , pp. 1270-1276
    • Petroff, O.A.1    Yu, R.K.2    Ogino, T.3
  • 64
    • 0035148720 scopus 로고    scopus 로고
    • Ageing choroid plexus-cerebrospinal fluid system
    • Preston, J. E. (2001). Ageing choroid plexus-cerebrospinal fluid system. Microsc. Res. Tech. 52, 31-37.
    • (2001) Microsc. Res. Tech. , vol.52 , pp. 31-37
    • Preston, J.E.1
  • 65
    • 0032891837 scopus 로고    scopus 로고
    • Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subsep-tic doses of lipopolysaccharide in the rat
    • Quan, N., Stern, E. L., Whiteside, M. B., and Herkenham, M. (1999). Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subsep-tic doses of lipopolysaccharide in the rat. J. Neuroimmunol. 93, 72-80.
    • (1999) J. Neuroimmunol. , vol.93 , pp. 72-80
    • Quan, N.1    Stern, E.L.2    Whiteside, M.B.3    Herkenham, M.4
  • 66
    • 0032031630 scopus 로고    scopus 로고
    • Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide
    • Quan, N., Whiteside, M., and Herkenham, M. (1998). Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide. Neuroscience 83, 281-293.
    • (1998) Neuroscience , vol.83 , pp. 281-293
    • Quan, N.1    Whiteside, M.2    Herkenham, M.3
  • 70
    • 0024260006 scopus 로고
    • Reduced prealbumin (transthyretin) in CSF of severely demented patients with Alzheimer's disease
    • Riisoen, H. (1988). Reduced prealbumin (transthyretin) in CSF of severely demented patients with Alzheimer's disease. Acta Neurol. Scand. 78, 455-459.
    • (1988) Acta Neurol. Scand. , vol.78 , pp. 455-459
    • Riisoen, H.1
  • 72
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
    • Rivera, E. J., Goldin, A., Fulmer, N., Tavares, R., Wands, J. R., and de la Monte, S. M. (2005). Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J. Alzheimers Dis. 8, 247-268.
    • (2005) J. Alzheimers Dis. , vol.8 , pp. 247-268
    • Rivera, E.J.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.R.5    de la Monte, S.M.6
  • 73
    • 0033525735 scopus 로고    scopus 로고
    • Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences
    • Rogers, J. T., Leiter, L. M., McPhee, J., Cahill, C. M., Zhan, S. S., Potter, H., and Nilsson, L. N. (1999). Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences. J. Biol. Chem. 274, 6421-6431.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6421-6431
    • Rogers, J.T.1    Leiter, L.M.2    McPhee, J.3    Cahill, C.M.4    Zhan, S.S.5    Potter, H.6    Nilsson, L.N.7
  • 76
    • 74449085808 scopus 로고    scopus 로고
    • Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins
    • Rouault, T. A., Zhang, D. L., and Jeong, S. Y. (2009). Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins. Metab. Brain Dis. 24, 673-684.
    • (2009) Metab. Brain Dis. , vol.24 , pp. 673-684
    • Rouault, T.A.1    Zhang, D.L.2    Jeong, S.Y.3
  • 77
    • 79957893994 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin: A new antioxidant that exerts its cyto-protective effect independent on Heme Oxygenase-1
    • Roudkenar, M. H., Halabian, R., Bahmani, P., Roushandeh, A. M., Kuwahara, Y., and Fukumoto, M. (2011). Neutrophil gelatinase-associated lipocalin: a new antioxidant that exerts its cyto-protective effect independent on Heme Oxygenase-1. Free Radic. Res. 45, 810-819.
    • (2011) Free Radic. Res. , vol.45 , pp. 810-819
    • Roudkenar, M.H.1    Halabian, R.2    Bahmani, P.3    Roushandeh, A.M.4    Kuwahara, Y.5    Fukumoto, M.6
  • 78
    • 65949096494 scopus 로고    scopus 로고
    • Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease
    • Salehi, Z., Mashayekhi, F., and Naji, M. (2008). Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease. Biofactors 33, 99-106.
    • (2008) Biofactors , vol.33 , pp. 99-106
    • Salehi, Z.1    Mashayekhi, F.2    Naji, M.3
  • 79
    • 39649115776 scopus 로고    scopus 로고
    • The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
    • Schmidt, P. J., Toran, P. T., Giannetti, A.M., Bjorkman, P. J., and Andrews, N. C. (2008). The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. Cell Metab. 7, 205-214.
    • (2008) Cell Metab. , vol.7 , pp. 205-214
    • Schmidt, P.J.1    Toran, P.T.2    Giannetti, A.M.3    Bjorkman, P.J.4    Andrews, N.C.5
  • 80
    • 1542778656 scopus 로고    scopus 로고
    • Choroid plexus, aging of the brain, and Alzheimer's disease
    • Serot, J. M., Bene, M. C., and Faure, G. C. (2003). Choroid plexus, aging of the brain, and Alzheimer's disease. Front. Biosci. 8, s515-s521.
    • (2003) Front. Biosci. , vol.8
    • Serot, J.M.1    Bene, M.C.2    Faure, G.C.3
  • 81
    • 0342545852 scopus 로고    scopus 로고
    • Morphological alterations of the choroid plexus in late-onset alzheimer's disease
    • Serot, J. M., Bene, M. C., Foliguet, B., and Faure, G. C. (2000). Morphological alterations of the choroid plexus in late-onset alzheimer's disease. Acta Neuropathol. 99, 105-108.
    • (2000) Acta Neuropathol. , vol.99 , pp. 105-108
    • Serot, J.M.1    Bene, M.C.2    Foliguet, B.3    Faure, G.C.4
  • 83
    • 54049133647 scopus 로고    scopus 로고
    • A potential pathogenetic role of iron in Alzheimer's disease
    • Silvestri, L., and Camaschella, C. (2008). A potential pathogenetic role of iron in Alzheimer's disease. J. Cell. Mol. Med. 12, 1548-1550.
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 1548-1550
    • Silvestri, L.1    Camaschella, C.2
  • 84
    • 38349194098 scopus 로고    scopus 로고
    • Furin-mediated release of soluble hemojuvelin: A new link between hypoxia and iron homeostasis
    • Silvestri, L., Pagani, A., and Camaschella, C. (2008). Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood 111, 924-931.
    • (2008) Blood , vol.111 , pp. 924-931
    • Silvestri, L.1    Pagani, A.2    Camaschella, C.3
  • 87
    • 23444439528 scopus 로고    scopus 로고
    • Systemic regulation of intestinal iron absorption
    • Steele, T. M., Frazer, D. M., and Anderson, G. J. (2005). Systemic regulation of intestinal iron absorption. IUBMB Life 57, 499-503.
    • (2005) IUBMB Life , vol.57 , pp. 499-503
    • Steele, T.M.1    Frazer, D.M.2    Anderson, G.J.3
  • 90
    • 4644223293 scopus 로고    scopus 로고
    • Estrogen increases brain expression of the mRNA encoding transthyretin, an amyloid beta scavenger protein
    • discussion 443-449
    • Tang, Y. P., Haslam, S. Z., Conrad, S. E., and Sisk, C. L. (2004). Estrogen increases brain expression of the mRNA encoding transthyretin, an amyloid beta scavenger protein. J. Alzheimers Dis. 6, 413-420. discussion 443-449.
    • (2004) J. Alzheimers Dis. , vol.6 , pp. 413-420
    • Tang, Y.P.1    Haslam, S.Z.2    Conrad, S.E.3    Sisk, C.L.4
  • 91
    • 0027170501 scopus 로고
    • Insulinlike growth factors and insulinlike growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type
    • Tham, A., Nordberg, A., Grissom, F. E., Carlsson-Skwirut, C., Viitanen, M., and Sara, V. R. (1993). Insulinlike growth factors and insulinlike growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type. J. Neural Transm. Park Dis. Dement. Sect. 5, 165-176.
    • (1993) J. Neural Transm. Park Dis. Dement. Sect. , vol.5 , pp. 165-176
    • Tham, A.1    Nordberg, A.2    Grissom, F.E.3    Carlsson-Skwirut, C.4    Viitanen, M.5    Sara, V.R.6
  • 94
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers: A decade of discovery
    • Walsh, D. M., and Selkoe, D. J. (2007). A beta oligomers: a decade of discovery. J. Neurochem. 101, 1172-1184.
    • (2007) J. Neurochem. , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 95
    • 14944378094 scopus 로고    scopus 로고
    • Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta andtherebyrescuelong-termpoten-tiation
    • Walsh, D. M., Townsend, M., Podlisny, M. B., Shankar, G. M., Fadeeva, J. V., El Agnaf, O., Hartley, D. M., and Selkoe, D. J. (2005). Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta andtherebyrescuelong-termpoten-tiation. J. Neurosci. 25, 2455-2462.
    • (2005) J. Neurosci. , vol.25 , pp. 2455-2462
    • Walsh, D.M.1    Townsend, M.2    Podlisny, M.B.3    Shankar, G.M.4    Fadeeva, J.V.5    El Agnaf, O.6    Hartley, D.M.7    Selkoe, D.J.8
  • 97
    • 0033583934 scopus 로고    scopus 로고
    • Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains: A quantitative study
    • Wen, G. Y., Wisniewski, H. M., and Kascsak, R. J. (1999). Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains: a quantitative study. Brain Res. 832, 40-46.
    • (1999) Brain Res. , vol.832 , pp. 40-46
    • Wen, G.Y.1    Wisniewski, H.M.2    Kascsak, R.J.3
  • 98
    • 83855163999 scopus 로고    scopus 로고
    • Pathogenic implications of iron accumulation in multiple sclerosis
    • Williams, R., Buchheit, C. L., Berman, N. E., and LeVine, S. M. (2012). Pathogenic implications of iron accumulation in multiple sclerosis. J. Neurochem. 120, 7-25.
    • (2012) J. Neurochem. , vol.120 , pp. 7-25
    • Williams, R.1    Buchheit, C.L.2    Berman, N.E.3    LeVine, S.M.4
  • 99
    • 77649192491 scopus 로고    scopus 로고
    • Choroid plexus: Biology and pathology
    • Wolburg, H., and Paulus, W. (2010). Choroid plexus: biology and pathology. Acta Neuropathol. 119, 75-88.
    • (2010) Acta Neuropathol. , vol.119 , pp. 75-88
    • Wolburg, H.1    Paulus, W.2
  • 101
    • 2542475986 scopus 로고    scopus 로고
    • Clearing amyloid through the blood-brain barrier
    • Zlokovic, B. V. (2004). Clearing amyloid through the blood-brain barrier. J. Neurochem. 89, 807-811.
    • (2004) J. Neurochem. , vol.89 , pp. 807-811
    • Zlokovic, B.V.1
  • 102
    • 0029920929 scopus 로고    scopus 로고
    • Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers
    • Zlokovic, B. V., Martel, C. L., Matsubara, E., McComb, J. G., Zheng, G., McCluskey, R. T., Frangione, B., and Ghiso, J. (1996). Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. Proc. Natl. Acad. Sci. U.S.A. 93, 4229-4234.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 4229-4234
    • Zlokovic, B.V.1    Martel, C.L.2    Matsubara, E.3    McComb, J.G.4    Zheng, G.5    McCluskey, R.T.6    Frangione, B.7    Ghiso, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.