Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins

Metabolic Brain Disease

Volumn 24, Issue 4, 2009, Pages 673-684

  Rouault, Tracey A ^a   Zhang, De Liang ^a   Jeong, Suh Young ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Blood brain barrier; Blood CSF barrier; Ceruloplasmin; Choroid plexus; Ferroportin; Iron transport

Indexed keywords

CERULOPLASMIN; FERRITIN; FERROPORTIN; IRON; MANGANESE; MESSENGER RNA; TRANSFERRIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN DEVELOPMENT; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHOROID PLEXUS; IMMUNOHISTOCHEMISTRY; IRON DEFICIENCY; IRON TRANSPORT; MOUSE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN LOCALIZATION;

ANIMALS; ATLASES AS TOPIC; BRAIN; BRAIN CHEMISTRY; BRAIN MAPPING; CAPILLARIES; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CERULOPLASMIN; CHOROID PLEXUS; EPITHELIAL CELLS; FERRITINS; GENE EXPRESSION; HOMEOSTASIS; IRON; MAGNETIC RESONANCE IMAGING; MICE; RNA, MESSENGER;

EID: 74449085808     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-009-9169-y     Document Type: Article

References (36)

1. Anderson GJ, Vulpe CD (2009) Mammalian iron transport. Cell Mol Life Sci 66:3241-3261
2. GJ Anderson DM Frazer GD McLaren 2009 Iron absorption and metabolism Curr Opin Gastroenterol 25 129 135 10.1097/MOG.0b013e32831ef1f7 1:CAS:528: DC%2BD1MXisFOht7Y%3D 19528880
3. I Aoki YJ Wu AC Silva RM Lynch AP Koretsky 2004 In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI Neuroimage 22 1046 1059 10.1016/j.neuroimage.2004.03.031 15219577 (Pubitemid 38829194)
4. JL Beard MK Hendricks EM Perez LE Murray-Kolb A Berg L Vernon-Feagans J Irlam W Isaacs A Sive M Tomlinson 2005 Maternal iron deficiency anemia affects postpartum emotions and cognition J Nutr 135 267 272 1:CAS:528: DC%2BD2MXhsVKjur4%3D 15671224
5. D Berg M Gerlach MB Youdim KL Double L Zecca P Riederer G Becker 2001 Brain iron pathways and their relevance to Parkinson's disease J Neurochem 79 225 236 10.1046/j.1471-4159.2001.00608.x 1:CAS:528:DC%2BD3MXnvFSmsr8%3D 11677250 (Pubitemid 32988938)
6. PD Brown SL Davies T Speake ID Millar 2004 Molecular mechanisms of cerebrospinal fluid production Neuroscience 129 957 970 10.1016/j.neuroscience. 2004.07.003 1:CAS:528:DC%2BD2cXhtVSlur7M 15561411 (Pubitemid 39556247)
7. Drubach D (1999) The brain explained. Prentice Hall, Upper Saddle River, New Jersey
8. SY Jeong S David 2006 Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice J Neurosci 26 9810 9819 10.1523/JNEUROSCI.2922-06.2006 1:CAS:528:DC%2BD28XhtVCgu7nF 16988052 (Pubitemid 44427720)
9. PA Johansson KM Dziegielewska SA Liddelow NR Saunders 2008 The blood-CSF barrier explained: when development is not immaturity Bioessays 30 237 248 10.1002/bies.20718 1:CAS:528:DC%2BD1cXkt1OisbY%3D 18293362 (Pubitemid 351341128)
10. RF Keep HC Jones 1990 A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat Brain Res Dev Brain Res 56 47 53 10.1016/0165-3806(90)90163- S 1:STN:280:DyaK3M7itFOntw%3D%3D 2279331 (Pubitemid 20298672)
11. L Koh G Nagra M Johnston 2007 Properties of the lymphatic cerebrospinal fluid transport system in the rat: impact of elevated intracranial pressure J Vasc Res 44 423 432 10.1159/000104255 17587862 (Pubitemid 47312663)
12. ES Lein, et al. 2007 Genome-wide atlas of gene expression in the adult mouse brain Nature 445 168 176 10.1038/nature05453 1:CAS:528: DC%2BD2sXjtFKjtw%3D%3D 17151600 (Pubitemid 46095716)
13. MA Maktabi DD Heistad FM Faraci 1990 Effects of angiotensin II on blood flow to choroid plexus Am J Physiol 258 H414 H418 1:CAS:528:DyaK3cXhsFantbs%3D 2309908
14. F Marques AM Falcao JC Sousa G Coppola D Geschwind N Sousa M Correia-Neves JA Palha 2009 Altered iron metabolism is part of the choroid plexus response to peripheral inflammation Endocrinology 150 2822 2828 10.1210/en.2008-1610 1:CAS:528:DC%2BD1MXmvVCqu70%3D 19213835
15. M Mastrogiannaki P Matak B Keith MC Simon S Vaulont C Peyssonnaux 2009 HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice J Clin Invest 119 1159 1166 10.1172/JCI38499 1:CAS:528:DC%2BD1MXlsFyrsbw%3D 19352007
16. AT McKie 2008 The role of Dcytb in iron metabolism: an update Biochem Soc Trans 36 1239 1241 10.1042/BST0361239 1:CAS:528:DC%2BD1cXhsVCgsLfF 19021532
17. MP Mims JT Prchal 2005 Divalent metal transporter 1 Hematology 10 339 345 10.1080/10245330500093419 1:CAS:528:DC%2BD2MXpvVShsbs%3D 16085548 (Pubitemid 41801131)
18. T Moos 2002 Brain iron homeostasis Dan Med Bull 49 279 301 1:CAS:528:DC%2BD3sXhtVGgs7o%3D 12553165
19. T Moos T Skjoerringe S Gosk EH Morgan 2006 Brain capillary endothelial cells mediate iron transport into the brain by segregating iron from transferrin without the involvement of divalent metal transporter 1 J Neurochem 98 1946 1958 10.1111/j.1471-4159.2006.04023.x 1:CAS:528:DC%2BD28XhtVCksb%2FN 16879716 (Pubitemid 44298257)
20. T Moos T Rosengren Nielsen T Skjorringe EH Morgan 2007 Iron trafficking inside the brain J Neurochem 103 1730 1740 10.1111/j.1471-4159.2007.04976.x 1:CAS:528:DC%2BD2sXhsVekt7nJ 17953660 (Pubitemid 350126643)
21. EH Morgan T Moos 2002 Mechanism and developmental changes in iron transport across the blood-brain barrier Dev Neurosci 24 106 113 10.1159/000065699 1:CAS:528:DC%2BD38Xot1Oisrw%3D 12401948 (Pubitemid 36151440)
22. RM Naeini JH Yoo JV Hunter 2009 Spectrum of choroid plexus lesions in children AJR Am J Roentgenol 192 32 40 10.2214/AJR.08.1128 19098176
23. RS Ohgami DR Campagna A McDonald MD Fleming 2006 The Steap proteins are metalloreductases Blood 108 1388 1394 10.1182/blood-2006-02-003681 1:CAS:528:DC%2BD28Xot1ymu7g%3D 16609065 (Pubitemid 44232042)
24. BN Patel RJ Dunn S David 2000 Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain JBC 275 4305 4310 10.1074/jbc.275.6.4305 1:CAS:528:DC%2BD3cXht12gtbo%3D (Pubitemid 30094671)
25. TA Rouault S Cooperman 2006 Brain iron metabolism Semin Pediatr Neurol 13 142 148 10.1016/j.spen.2006.08.002 17101452 (Pubitemid 44709651)
26. TA Rouault WH Tong 2008 Iron-sulfur cluster biogenesis and human disease Trends Genet 24 398 407 10.1016/j.tig.2008.05.008 1:CAS:528:DC%2BD1cXoslChsLs%3D 18606475
27. YM Shah T Matsubara S Ito SH Yim FJ Gonzalez 2009 Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency Cell Metab 9 152 164 10.1016/j.cmet.2008.12.012 1:CAS:528:DC%2BD1MXnt12quro%3D 19147412
28. T Speake JD Kibble PD Brown 2004 Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells Am J Physiol Cell Physiol 286 C611 C620 10.1152/ajpcell.00292.2003 1:CAS:528:DC%2BD2cXitlSgs7k%3D 14602579
29. D Su JM May MJ Koury H Asard 2006 Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling J Biol Chem 281 39852 39859 10.1074/jbc.M606543200 1:CAS:528:DC%2BD28XhtlCrtrbK 17068337 (Pubitemid 46041788)
30. SP Walker, et al. 2007 Child development: risk factors for adverse outcomes in developing countries Lancet 369 145 157 10.1016/S0140-6736(07)60076- 2 17223478 (Pubitemid 46073134)
31. M Wessling-Resnick 2006 Iron imports. III. Transfer of iron from the mucosa into circulation Am J Physiol Gastrointest Liver Physiol 290 G1 G6 10.1152/ajpgi.00415.2005 1:CAS:528:DC%2BD28XhsVSisbs%3D 16354771
32. LJ Wu, et al. 2004 Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier Brain Res 1001 108 117 10.1016/j.brainres.2003.10.066 1:CAS:528:DC%2BD2cXht1yrsrY%3D 14972659 (Pubitemid 38221533)
33. MB Youdim 2008 Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus Neurotox Res 14 45 56 10.1007/BF03033574 1:CAS:528:DC%2BD1MXpsFWqtA%3D%3D 18790724
34. L Zecca MB Youdim P Riederer JR Connor RR Crichton 2004 Iron, brain ageing and neurodegenerative disorders Nat Rev Neurosci 5 863 873 10.1038/nrn1537 1:CAS:528:DC%2BD2cXos1Ojtrc%3D 15496864 (Pubitemid 39482155)
35. DL Zhang D Su A Berczi A Vargas H Asard 2006 An ascorbate-reducible cytochrome b561 is localized in macrophage lysosomes Biochim Biophys Acta 1760 1903 1913 1:CAS:528:DC%2BD28XhtF2qurbM 16996694 (Pubitemid 44692367)
36. W Zheng M Aschner JF Ghersi-Egea 2003 Brain barrier systems: a new frontier in metal neurotoxicological research Toxicol Appl Pharmacol 192 1 11 10.1016/S0041-008X(03)00251-5 1:CAS:528:DC%2BD3sXnvVyrtbc%3D 14554098 (Pubitemid 37205113)