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Volumn 55, Issue 1, 2011, Pages 32-38

Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease

Author keywords

Alzheimer's disease; Amyloid plaques; Copper; Cortex; Hippocampus; Imaging; Iron; Transgenic mice; X ray fluorescence; Zinc

Indexed keywords

COPPER; IRON; ZINC;

EID: 78951481093     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2010.11.073     Document Type: Article
Times cited : (117)

References (42)
  • 3
    • 1842451926 scopus 로고    scopus 로고
    • Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases
    • Bartzokis G., Tishler T.A., Shin I.S., Lu P.H., Cummings J.L. Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases. Ann. NY Acad. Sci. 2004, 1012:224-236.
    • (2004) Ann. NY Acad. Sci. , vol.1012 , pp. 224-236
    • Bartzokis, G.1    Tishler, T.A.2    Shin, I.S.3    Lu, P.H.4    Cummings, J.L.5
  • 4
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
    • (1991) Acta Neuropathol. , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 5
  • 6
    • 0037386086 scopus 로고    scopus 로고
    • The metallobiology of Alzheimer's disease
    • Bush A.I. The metallobiology of Alzheimer's disease. Trends Neurosci. 2003, 26:207-214.
    • (2003) Trends Neurosci. , vol.26 , pp. 207-214
    • Bush, A.I.1
  • 7
    • 0026590705 scopus 로고
    • Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease
    • Connor J.R., Snyder B.S., Beard J.L., Fine R.E., Mufson E.J. Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease. J. Neurosci. Res. 1992, 31:327-335.
    • (1992) J. Neurosci. Res. , vol.31 , pp. 327-335
    • Connor, J.R.1    Snyder, B.S.2    Beard, J.L.3    Fine, R.E.4    Mufson, E.J.5
  • 8
    • 0030891254 scopus 로고    scopus 로고
    • Zinc and Alzheimer's disease: is there a direct link?
    • Cuajungco M.P., Lees G.J. Zinc and Alzheimer's disease: is there a direct link?. Brain Res. Brain Res. Rev. 1997, 23:219-236.
    • (1997) Brain Res. Brain Res. Rev. , vol.23 , pp. 219-236
    • Cuajungco, M.P.1    Lees, G.J.2
  • 9
    • 0030297178 scopus 로고    scopus 로고
    • Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress
    • Deibel M.A., Ehmann W.D., Markesbery W.R. Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. J. Neurol. Sci. 1996, 143:137-142.
    • (1996) J. Neurol. Sci. , vol.143 , pp. 137-142
    • Deibel, M.A.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 10
    • 33645053770 scopus 로고    scopus 로고
    • Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer's disease
    • El Tannir El Tayara N., Delatour B., Le Cudennec C., Guegan M., Volk A., Dhenain M. Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 2006, 22:199-208.
    • (2006) Neurobiol. Dis. , vol.22 , pp. 199-208
    • El Tannir El Tayara, N.1    Delatour, B.2    Le Cudennec, C.3    Guegan, M.4    Volk, A.5    Dhenain, M.6
  • 12
    • 0033013737 scopus 로고    scopus 로고
    • MR imaging of human brain at 3.0T: preliminary report on transverse relaxation rates and relation to estimated iron content
    • Gelman N., Gorell J.M., Barker P.B., Savage R.M., Spickler E.M., Windham J.P., Knight R.A. MR imaging of human brain at 3.0T: preliminary report on transverse relaxation rates and relation to estimated iron content. Radiology 1999, 210:759-767.
    • (1999) Radiology , vol.210 , pp. 759-767
    • Gelman, N.1    Gorell, J.M.2    Barker, P.B.3    Savage, R.M.4    Spickler, E.M.5    Windham, J.P.6    Knight, R.A.7
  • 13
    • 0030780381 scopus 로고    scopus 로고
    • Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts
    • Giannakopoulos P., Hof P.R., Michel J.P., Guimon J., Bouras C. Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts. Brain Res. Brain Res. Rev. 1997, 25:217-245.
    • (1997) Brain Res. Brain Res. Rev. , vol.25 , pp. 217-245
    • Giannakopoulos, P.1    Hof, P.R.2    Michel, J.P.3    Guimon, J.4    Bouras, C.5
  • 14
    • 0032898122 scopus 로고    scopus 로고
    • Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy
    • Griffiths P.D., Dobson B.R., Jones G.R., Clarke D.T. Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy. Brain 1999, 122:667-673.
    • (1999) Brain , vol.122 , pp. 667-673
    • Griffiths, P.D.1    Dobson, B.R.2    Jones, G.R.3    Clarke, D.T.4
  • 15
    • 0026569388 scopus 로고
    • An improved thioflavine S method for staining neurofibrillary tangles and senile plaques in Alzheimer's disease
    • Guntern R., Bouras C., Hof P.R., Vallet P.G. An improved thioflavine S method for staining neurofibrillary tangles and senile plaques in Alzheimer's disease. Experientia 1992, 48:8-10.
    • (1992) Experientia , vol.48 , pp. 8-10
    • Guntern, R.1    Bouras, C.2    Hof, P.R.3    Vallet, P.G.4
  • 20
    • 42149176118 scopus 로고    scopus 로고
    • Genetic analysis reveals polygenic influences on iron, copper, and zinc in mouse hippocampus with neurobiological implications
    • Jones L.C., Beard J.L., Jones B.C. Genetic analysis reveals polygenic influences on iron, copper, and zinc in mouse hippocampus with neurobiological implications. Hippocampus 2008, 18:398-410.
    • (2008) Hippocampus , vol.18 , pp. 398-410
    • Jones, L.C.1    Beard, J.L.2    Jones, B.C.3
  • 21
    • 0037188530 scopus 로고    scopus 로고
    • Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice
    • Lee J.Y., Cole T.B., Palmiter R.D., Suh S.W., Koh J.Y. Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc. Natl Acad. Sci. USA 2002, 99:7705-7710.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 7705-7710
    • Lee, J.Y.1    Cole, T.B.2    Palmiter, R.D.3    Suh, S.W.4    Koh, J.Y.5
  • 22
    • 0033139740 scopus 로고    scopus 로고
    • Histochemically reactive zinc in plaques of the Swedish mutant β-amyloid precursor protein transgenic mice
    • Lee J.Y., Mook-Jung I., Koh J.Y. Histochemically reactive zinc in plaques of the Swedish mutant β-amyloid precursor protein transgenic mice. J. Neurosci. 1999, 19:RC10.
    • (1999) J. Neurosci. , vol.19
    • Lee, J.Y.1    Mook-Jung, I.2    Koh, J.Y.3
  • 23
    • 67651020783 scopus 로고    scopus 로고
    • Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease
    • Leskovjan A.C., Lanzirotti A., Miller L.M. Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease. Neuroimage 2009, 47:1215-1220.
    • (2009) Neuroimage , vol.47 , pp. 1215-1220
    • Leskovjan, A.C.1    Lanzirotti, A.2    Miller, L.M.3
  • 27
    • 33745027879 scopus 로고    scopus 로고
    • Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics
    • Masters C.L., Cappai R., Barnham K.J., Villemagne V.L. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J. Neurochem. 2006, 97:1700-1725.
    • (2006) J. Neurochem. , vol.97 , pp. 1700-1725
    • Masters, C.L.1    Cappai, R.2    Barnham, K.J.3    Villemagne, V.L.4
  • 28
    • 34147107527 scopus 로고    scopus 로고
    • Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts
    • Michaeli S., Oz G., Sorce D.J., Garwood M., Ugurbil K., Majestic S., Tuite P. Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts. Mov. Disord. 2007, 22:334-340.
    • (2007) Mov. Disord. , vol.22 , pp. 334-340
    • Michaeli, S.1    Oz, G.2    Sorce, D.J.3    Garwood, M.4    Ugurbil, K.5    Majestic, S.6    Tuite, P.7
  • 29
    • 33745004381 scopus 로고    scopus 로고
    • Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with β-amyloid deposits in Alzheimer's disease
    • Miller L.M., Wang Q., Telivala T.P., Smith R.J., Lanzirotti A., Miklossy J. Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with β-amyloid deposits in Alzheimer's disease. J. Struct. Biol. 2006, 155:30-37.
    • (2006) J. Struct. Biol. , vol.155 , pp. 30-37
    • Miller, L.M.1    Wang, Q.2    Telivala, T.P.3    Smith, R.J.4    Lanzirotti, A.5    Miklossy, J.6
  • 30
  • 31
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
    • Price J.L., Morris J.C. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann. Neurol. 1999, 45:358-368.
    • (1999) Ann. Neurol. , vol.45 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 33
    • 12244310498 scopus 로고    scopus 로고
    • Magnetic resonance imaging of brain iron
    • Schenck J.F. Magnetic resonance imaging of brain iron. J. Neurol. Sci. 2003, 207:99-102.
    • (2003) J. Neurol. Sci. , vol.207 , pp. 99-102
    • Schenck, J.F.1
  • 37
    • 0033986037 scopus 로고    scopus 로고
    • Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains
    • Suh S.W., Jensen K.B., Jensen M.S., Silva D.S., Kesslak P.J., Danscher G., Frederickson C.J. Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains. Brain Res. 2000, 852:274-278.
    • (2000) Brain Res. , vol.852 , pp. 274-278
    • Suh, S.W.1    Jensen, K.B.2    Jensen, M.S.3    Silva, D.S.4    Kesslak, P.J.5    Danscher, G.6    Frederickson, C.J.7
  • 40
    • 0037687691 scopus 로고    scopus 로고
    • MAPS: a set of software tools for analysis and visualization of 3D X-ray fluorescence data sets
    • Vogt S. MAPS: a set of software tools for analysis and visualization of 3D X-ray fluorescence data sets. J. Phys. IV 2003, 104:635-638.
    • (2003) J. Phys. IV , vol.104 , pp. 635-638
    • Vogt, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.