Propagation of the prion phenomenon: Beyond the seeding principle

Journal of Molecular Biology

Volumn 421, Issue 4-5, 2012, Pages 491-498

  Münch, Christian ^a   Bertolotti, Anne ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

aggregation; amyloid; neurodegenerative diseases; prion; prion like

Indexed keywords

PRION PROTEIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; DEGENERATIVE DISEASE; HUMAN; HUNTINGTON CHOREA; NONHUMAN; PARKINSON DISEASE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN POLYMERIZATION; REVIEW;

EID: 84863986711     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.12.061     Document Type: Review

References (52)

1. Aguzzi A., and Calella A.M. Prions: protein aggregation and infectious diseases Physiol. Rev. 89 2009 1105 1152
2. Prusiner S.B. Novel proteinaceous infectious particles cause scrapie Science 216 1982 136 144 (Pubitemid 12089840)
3. Soto C. Prion hypothesis: the end of the controversy? Trends Biochem. Sci. 36 2010 151 158
4. Chiti F., and Dobson C.M. Protein misfolding, functional amyloid, and human disease Annu. Rev. Biochem. 75 2006 333 366 (Pubitemid 44118036)
5. Braak H., Rub U., Gai W.P., and Del Tredici K. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen J. Neural Transm. 110 2003 517 536 (Pubitemid 36543283)
6. Braak H., and Braak E. Neuropathological stageing of Alzheimer-related changes Acta Neuropathol. 82 1991 239 259
7. Ravits J., Paul P., and Jorg C. Focality of upper and lower motor neuron degeneration at the clinical onset of ALS Neurology 68 2007 1571 1575 (Pubitemid 46717980)
8. Vonsattel J.P., and DiFiglia M. Huntington disease J. Neuropathol. Exp. Neurol. 57 1998 369 384 (Pubitemid 28237321)
9. Gajdusek D.C., Gibbs C.J., and Alpers M. Experimental transmission of a kuru-like syndrome to chimpanzees Nature 209 1966 794 796
10. Kane M.D., Lipinski W.J., Callahan M.J., Bian F., Durham R.A., and Schwarz R.D. Evidence for seeding of β-amyloid by intracerebral infusion of Alzheimer brain extracts in β-amyloid precursor protein-transgenic mice J. Neurosci. 20 2000 3606 3611 (Pubitemid 30266223)
11. Meyer-Luehmann M., Coomaraswamy J., Bolmont T., Kaeser S., Schaefer C., and Kilger E. Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host Science 313 2006 1781 1784 (Pubitemid 44454153)
12. Eisele Y.S., Obermuller U., Heilbronner G., Baumann F., Kaeser S.A., and Wolburg H. Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis Science 330 2010 980 982
13. Clavaguera F., Bolmont T., Crowther R.A., Abramowski D., Frank S., and Probst A. Transmission and spreading of tauopathy in transgenic mouse brain Nat. Cell Biol. 11 2009 909 913
14. Mougenot A.L., Nicot S., Bencsik A., Morignat E., Verchere J., and Lakhdar L. Prion-like acceleration of a synucleinopathy in a transgenic mouse model Neurobiol. Aging 2011 [Epub ahead of print]
15. Kordower J.H., Chu Y., Hauser R.A., Freeman T.B., and Olanow C.W. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease Nat. Med. 14 2008 504 506 (Pubitemid 351655212)
16. Li J.Y., Englund E., Holton J.L., Soulet D., Hagell P., and Lees A.J. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation Nat. Med. 14 2008 501 503 (Pubitemid 351655211)
17. Yang W., Dunlap J.R., Andrews R.B., and Wetzel R. Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells Hum. Mol. Genet. 11 2002 2905 2917
18. Luk K.C., Song C., O'Brien P., Stieber A., Branch J.R., and Brunden K.R. Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells Proc. Natl Acad. Sci. USA 106 2009 20051 20056
19. Guo J.L., and Lee V.M. Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles J. Biol. Chem. 286 2011 15317 15331
20. Furukawa Y., Kaneko K., Watanabe S., Yamanaka K., and Nukina N. A seeding reaction recapitulates intracellular formation of sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions J. Biol. Chem. 286 2011 18664 18672
21. Ren P.H., Lauckner J.E., Kachirskaia I., Heuser J.E., Melki R., and Kopito R.R. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates Nat. Cell Biol. 11 2009 219 225
22. Danzer K.M., Haasen D., Karow A.R., Moussaud S., Habeck M., and Giese A. Different species of α-synuclein oligomers induce calcium influx and seeding J. Neurosci. 27 2007 9220 9232 (Pubitemid 47312071)
23. Danzer K.M., Krebs S.K., Wolff M., Birk G., and Hengerer B. Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology J. Neurochem. 111 2009 192 203
24. Desplats P., Lee H.J., Bae E.J., Patrick C., Rockenstein E., and Crews L. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein Proc. Natl Acad. Sci. USA 106 2009 13010 13015
25. Hansen C., Angot E., Bergstrom A.L., Steiner J.A., Pieri L., and Paul G. α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells J. Clin. Invest. 121 2011 715 725
26. Volpicelli-Daley L.A., Luk K.C., Patel T.P., Tanik S.A., Riddle D.M., and Stieber A. Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death Neuron 72 2011 57 71
27. Frost B., Jacks R.L., and Diamond M.I. Propagation of tau misfolding from the outside to the inside of a cell J. Biol. Chem. 284 2009 12845 12852
28. Munch C., O'Brien J., and Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells Proc. Natl Acad. Sci. USA 108 2011 3548 3553
29. Urushitani M., Sik A., Sakurai T., Nukina N., Takahashi R., and Julien J.P. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis Nat. Neurosci. 9 2006 108 118 (Pubitemid 43011916)
30. Langer F., Eisele Y.S., Fritschi S.K., Staufenbiel M., Walker L.C., and Jucker M. Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition J. Neurosci. 31 2011 14488 14495
31. Uptain S.M., and Lindquist S. Prions as protein-based genetic elements Annu. Rev. Microbiol. 56 2002 703 741 (Pubitemid 35217472)
32. Krammer C., Kryndushkin D., Suhre M.H., Kremmer E., Hofmann A., and Pfeifer A. The yeast Sup35NM domain propagates as a prion in mammalian cells Proc. Natl Acad. Sci. USA 106 2009 462 467
33. Bruijn L.I., Miller T.M., and Cleveland D.W. Unraveling the mechanisms involved in motor neuron degeneration in ALS Annu. Rev. Neurosci. 27 2004 723 749 (Pubitemid 39050419)
34. Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., and Chou T.T. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133 (Pubitemid 44547757)
35. Sreedharan J., Blair I.P., Tripathi V.B., Hu X., Vance C., and Rogelj B. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis Science 319 2008 1668 1672 (Pubitemid 351432505)
36. Bosco D.A., Morfini G., Karabacak N.M., Song Y., Gros-Louis F., and Pasinelli P. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS Nat. Neurosci. 13 2010 1396 1403
37. G93A mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis PLoS One 5 2010 e10627
38. Grad L.I., Guest W.C., Yanai A., Pokrishevsky E., O'Neill M.A., and Gibbs E. Intermolecular transmission of superoxide dismutase 1 misfolding in living cells Proc. Natl Acad. Sci. USA 108 2011 16398 16403
39. Boillee S., Yamanaka K., Lobsiger C.S., Copeland N.G., Jenkins N.A., and Kassiotis G. Onset and progression in inherited ALS determined by motor neurons and microglia Science 312 2006 1389 1392 (Pubitemid 43839552)
40. Urushitani M., Ezzi S.A., and Julien J.P. Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis Proc. Natl Acad. Sci. USA 104 2007 2495 2500 (Pubitemid 46391424)
41. Asuni A.A., Boutajangout A., Scholtzova H., Knudsen E., Li Y.S., and Quartermain D. Vaccination of Alzheimer's model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages Eur. J. Neurosci. 24 2006 2530 2542 (Pubitemid 44726765)
42. Asuni A.A., Boutajangout A., Quartermain D., and Sigurdsson E.M. Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements J. Neurosci. 27 2007 9115 9129 (Pubitemid 47312068)
43. Rujano M.A., Bosveld F., Salomons F.A., Dijk F., van Waarde M.A., and van der Want J.J. Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes PLoS Biol. 4 2006 e417
44. Tanaka M., Collins S.R., Toyama B.H., and Weissman J.S. The physical basis of how prion conformations determine strain phenotypes Nature 442 2006 585 589 (Pubitemid 44167919)
45. Hou F., Sun L., Zheng H., Skaug B., Jiang Q.X., and Chen Z.J. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response Cell 146 2011 448 461
46. Ye J., and Maniatis T. A prion-like trigger of antiviral signaling Cell 146 2011 348 350
47. Heinrich S.U., and Lindquist S. Protein-only mechanism induces self-perpetuating changes in the activity of neuronal Aplysia cytoplasmic polyadenylation element binding protein (CPEB) Proc. Natl Acad. Sci. USA 108 2011 2999 3004
48. Si K., Lindquist S., and Kandel E.R. A neuronal isoform of the Aplysia CPEB has prion-like properties Cell 115 2003 879 891 (Pubitemid 38058499)
49. Saborio G.P., Permanne B., and Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding Nature 411 2001 810 813 (Pubitemid 32588105)
50. Atarashi R., Wilham J.M., Christensen L., Hughson A.G., Moore R.A., and Johnson L.M. Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking Nat. Methods 5 2008 211 212 (Pubitemid 351325633)
51. Legname G., Baskakov I.V., Nguyen H.O., Riesner D., Cohen F.E., DeArmond S.J., and Prusiner S.B. Synthetic mammalian prions Science 305 2004 673 676 (Pubitemid 39006757)
52. Wang F., Wang X., Yuan C.G., and Ma J. Generating a prion with bacterially expressed recombinant prion protein Science 327 2010 1132 1135