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Volumn 276, Issue 1-2, 2012, Pages 10-15

Role of CREM in systemic lupus erythematosus

Author keywords

Autoimmune; CAMP response element modulator; Systemic lupus erythematosus

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 1; CD28 ANTIGEN; CD3 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; INTERLEUKIN 10; INTERLEUKIN 2; PROTEIN C FOS; PROTEIN KINASE SYK; PROTEIN P300;

EID: 84863858849     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2012.04.008     Document Type: Review
Times cited : (10)

References (67)
  • 1
    • 0031710196 scopus 로고    scopus 로고
    • Immune cell signaling aberrations in human lupus
    • Liossis S.N., Sfikakis P.P., Tsokos G.C. Immune cell signaling aberrations in human lupus. Immunol. Res. 1998, 18:27-39.
    • (1998) Immunol. Res. , vol.18 , pp. 27-39
    • Liossis, S.N.1    Sfikakis, P.P.2    Tsokos, G.C.3
  • 2
    • 61349083564 scopus 로고    scopus 로고
    • Identification of regulatory T cells in systemic lupus erythematosus
    • Gerli R., Nocentini G., Alunno A., et al. Identification of regulatory T cells in systemic lupus erythematosus. Autoimmun. Rev. 2009, 8:426-430.
    • (2009) Autoimmun. Rev. , vol.8 , pp. 426-430
    • Gerli, R.1    Nocentini, G.2    Alunno, A.3
  • 4
    • 84855557634 scopus 로고    scopus 로고
    • Regulatory T-cell-associated cytokines in systemic lupus erythematosys
    • Okamoto A., Fujio K., Okamura T., et al. Regulatory T-cell-associated cytokines in systemic lupus erythematosys. J. Biomed. Biotechnol. 2011, 2011:463412.
    • (2011) J. Biomed. Biotechnol. , vol.2011 , pp. 463412
    • Okamoto, A.1    Fujio, K.2    Okamura, T.3
  • 5
    • 77953410068 scopus 로고    scopus 로고
    • Harnessing regulatory T cells for the therapy of lupus and other autoimmune diseases
    • Sharabi A., Mozes E. Harnessing regulatory T cells for the therapy of lupus and other autoimmune diseases. Immunotherapy 2009, 1:385-401.
    • (2009) Immunotherapy , vol.1 , pp. 385-401
    • Sharabi, A.1    Mozes, E.2
  • 6
    • 0242403301 scopus 로고    scopus 로고
    • Quantification of regulatory T cells in patients with systemic lupus erythematosus
    • Crispin J.C., Martínez A., Alcocer-Varela J. Quantification of regulatory T cells in patients with systemic lupus erythematosus. J. Autoimmun. 2003, 21:273-276.
    • (2003) J. Autoimmun. , vol.21 , pp. 273-276
    • Crispin, J.C.1    Martínez, A.2    Alcocer-Varela, J.3
  • 7
    • 33846900430 scopus 로고    scopus 로고
    • Deficient CD4+CD25 high T regulatory cell function in patients with active systemic lupus erythematosus
    • Valencia X., Yarboro C., Illei G., et al. Deficient CD4+CD25 high T regulatory cell function in patients with active systemic lupus erythematosus. J. Immunol. 2007, 178:2579-2588.
    • (2007) J. Immunol. , vol.178 , pp. 2579-2588
    • Valencia, X.1    Yarboro, C.2    Illei, G.3
  • 8
    • 49449104712 scopus 로고    scopus 로고
    • Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients
    • Hahn B.H., Anderson M., Le E., et al. Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients. Arthritis Rheum. 2008, 58:2488-2497.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2488-2497
    • Hahn, B.H.1    Anderson, M.2    Le, E.3
  • 9
    • 29144516273 scopus 로고    scopus 로고
    • Global natural regulatory T cell depletion in active systemic lupus erythematosus
    • Miyara M., Amoura Z., Parizot C., et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J. Immunol. 2005, 175:8392-8400.
    • (2005) J. Immunol. , vol.175 , pp. 8392-8400
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3
  • 10
    • 77949264323 scopus 로고    scopus 로고
    • Increased serum interleukin 17 in patients with systemic lupus erythematosus
    • Zhao X.F., Pan H.F., Yuan H., et al. Increased serum interleukin 17 in patients with systemic lupus erythematosus. Mol. Biol. Rep. 2010, 37:81-86.
    • (2010) Mol. Biol. Rep. , vol.37 , pp. 81-86
    • Zhao, X.F.1    Pan, H.F.2    Yuan, H.3
  • 11
    • 77951117432 scopus 로고    scopus 로고
    • Low level of serum interleukin 27 in patients with systemic lupus erythematosus
    • Li T.T., Zhang T., Chen G.M., et al. Low level of serum interleukin 27 in patients with systemic lupus erythematosus. J. Investig. Med. 2010, 58:737-739.
    • (2010) J. Investig. Med. , vol.58 , pp. 737-739
    • Li, T.T.1    Zhang, T.2    Chen, G.M.3
  • 12
    • 58549120006 scopus 로고    scopus 로고
    • Decreased serum IL-22 levels in patients with systemic lupus erythematosus
    • Pan H.F., Zhao X.F., Yuan H., et al. Decreased serum IL-22 levels in patients with systemic lupus erythematosus. Clin. Chim. Acta 2009, 401:179-180.
    • (2009) Clin. Chim. Acta , vol.401 , pp. 179-180
    • Pan, H.F.1    Zhao, X.F.2    Yuan, H.3
  • 13
    • 67649197343 scopus 로고    scopus 로고
    • Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
    • Doreau A., Belot A., Bastid J., et al. Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat. Immunol. 2009, 10:778-785.
    • (2009) Nat. Immunol. , vol.10 , pp. 778-785
    • Doreau, A.1    Belot, A.2    Bastid, J.3
  • 14
    • 0020546709 scopus 로고
    • Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE)
    • Linker-Israeli M., Bakke A.C., Kitridou R.C., et al. Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE). J. Immunol. 1983, 130:2651-2655.
    • (1983) J. Immunol. , vol.130 , pp. 2651-2655
    • Linker-Israeli, M.1    Bakke, A.C.2    Kitridou, R.C.3
  • 15
    • 0028904325 scopus 로고
    • Analysis of proteins that interact with the IL-2 regulatory region in patients with rheumatic diseases
    • Becker H., Stengl G., Stein M., et al. Analysis of proteins that interact with the IL-2 regulatory region in patients with rheumatic diseases. Clin. Exp. Immunol. 1995, 99:325-330.
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 325-330
    • Becker, H.1    Stengl, G.2    Stein, M.3
  • 16
    • 0025668444 scopus 로고
    • Soluble immubologic products in scleroderma sera
    • Kahaleh M.B. Soluble immubologic products in scleroderma sera. Clin. Immunol. Immunopathol. 1991, 58:139-144.
    • (1991) Clin. Immunol. Immunopathol. , vol.58 , pp. 139-144
    • Kahaleh, M.B.1
  • 17
    • 43949164661 scopus 로고
    • Signal transduction events leading to T-cell lymphokine gene expression
    • Fraser J.D., Straus D., Weiss A. Signal transduction events leading to T-cell lymphokine gene expression. Immunol. Today 1993, 14:357-362.
    • (1993) Immunol. Today , vol.14 , pp. 357-362
    • Fraser, J.D.1    Straus, D.2    Weiss, A.3
  • 18
    • 0024920023 scopus 로고
    • From cell code to gene code: Cytokines and transcription factors
    • Muegge K., Durum S.K. From cell code to gene code: Cytokines and transcription factors. New Biol. 1989, 1:239-246.
    • (1989) New Biol. , vol.1 , pp. 239-246
    • Muegge, K.1    Durum, S.K.2
  • 19
    • 58149459511 scopus 로고    scopus 로고
    • Transcriptional regulation of IL-2 in health and autoimmunity
    • Crispín J.C., Tsokos G.C. Transcriptional regulation of IL-2 in health and autoimmunity. Autoimmun. Rev. 2009, 8:190-195.
    • (2009) Autoimmun. Rev. , vol.8 , pp. 190-195
    • Crispín, J.C.1    Tsokos, G.C.2
  • 20
    • 18244375249 scopus 로고    scopus 로고
    • Egr-2 and Egr-3 are negative regulators of T cell activation
    • Safford M., Collins S., Luzt M.A., et al. Egr-2 and Egr-3 are negative regulators of T cell activation. Nat. Immunol. 2005, 6:472-480.
    • (2005) Nat. Immunol. , vol.6 , pp. 472-480
    • Safford, M.1    Collins, S.2    Luzt, M.A.3
  • 21
    • 0029090347 scopus 로고
    • A regulatory element in the human interleukin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1
    • Skerka C., Decker E.L., Zipfel P.F. A regulatory element in the human interleukin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1. J. Biol. Chem. 1995, 270:22500-22506.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22500-22506
    • Skerka, C.1    Decker, E.L.2    Zipfel, P.F.3
  • 22
    • 33845403096 scopus 로고    scopus 로고
    • Cutting Edge: TCR-induced NAB2 enhances T cell function by coactivating IL-2 transcription
    • Collins S., Wolfraim L.A., Drake C.G., et al. Cutting Edge: TCR-induced NAB2 enhances T cell function by coactivating IL-2 transcription. J. Immunol. 2006, 177:8301-8305.
    • (2006) J. Immunol. , vol.177 , pp. 8301-8305
    • Collins, S.1    Wolfraim, L.A.2    Drake, C.G.3
  • 23
    • 78649255039 scopus 로고    scopus 로고
    • Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice
    • Mathenia J., Reyes-Cortes E., Williams S., et al. Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice. Clin. Exp. Immunol. 2010, 162:362-371.
    • (2010) Clin. Exp. Immunol. , vol.162 , pp. 362-371
    • Mathenia, J.1    Reyes-Cortes, E.2    Williams, S.3
  • 24
    • 34247215187 scopus 로고    scopus 로고
    • Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
    • Ono M., Yaguchi H., Ohkura N., et al. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature 2007, 446:685-689.
    • (2007) Nature , vol.446 , pp. 685-689
    • Ono, M.1    Yaguchi, H.2    Ohkura, N.3
  • 25
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
    • Prokunina L., Castillejo-López C., Oberg F., et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat. Genet. 2002, 32:666-669.
    • (2002) Nat. Genet. , vol.32 , pp. 666-669
    • Prokunina, L.1    Castillejo-López, C.2    Oberg, F.3
  • 26
    • 0029041568 scopus 로고
    • Transcriptional regulation of the IL-2 gene
    • Jain J., Loh C., Rao A. Transcriptional regulation of the IL-2 gene. Curr. Opin. Immunol. 1995, 7:333-342.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 333-342
    • Jain, J.1    Loh, C.2    Rao, A.3
  • 27
    • 0035869333 scopus 로고    scopus 로고
    • Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus
    • Solomou E.E., Juang Y.T., Gourley M.F., et al. Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus. J. Immunol. 2001, 166:4216-4222.
    • (2001) J. Immunol. , vol.166 , pp. 4216-4222
    • Solomou, E.E.1    Juang, Y.T.2    Gourley, M.F.3
  • 28
    • 27144541457 scopus 로고    scopus 로고
    • The cyclic AMP response element modulator regulates transcription of the TCR-ζChain
    • Tenbrock K., Kyttaris V.C., Ahlmann M., et al. The cyclic AMP response element modulator regulates transcription of the TCR-ζChain. J. Immunol. 2005, 17:5975-5980.
    • (2005) J. Immunol. , vol.17 , pp. 5975-5980
    • Tenbrock, K.1    Kyttaris, V.C.2    Ahlmann, M.3
  • 29
    • 4344718846 scopus 로고    scopus 로고
    • Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus
    • Kyttaris V.C., Juang Y.T., Tenbrock K., et al. Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus. J. Immunol. 2004, 173:3557-3563.
    • (2004) J. Immunol. , vol.173 , pp. 3557-3563
    • Kyttaris, V.C.1    Juang, Y.T.2    Tenbrock, K.3
  • 30
    • 80052731499 scopus 로고    scopus 로고
    • A novel intronic cAMP response element modulator (CREM) promoter is regulated by activator protein-1 (AP-1) and accounts for altered activation-induced CREM expression in T cells from patients with systemic lupus erythematosus
    • Rauen T., Benedyk K., Juang Y.T., et al. A novel intronic cAMP response element modulator (CREM) promoter is regulated by activator protein-1 (AP-1) and accounts for altered activation-induced CREM expression in T cells from patients with systemic lupus erythematosus. J. Biol. Chem. 2011, 286:32366-32372.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32366-32372
    • Rauen, T.1    Benedyk, K.2    Juang, Y.T.3
  • 31
    • 78751488886 scopus 로고    scopus 로고
    • Transcriptional activation of the cAMP-responsive modulator promoter in human T cells is regulated by protein phosphatase 2A-mediated dephosphorylation of SP-1 and reflects disease activity in patients with systemic lupus erythematosus
    • Juang Y.T., Rauen T., Wang Y., et al. Transcriptional activation of the cAMP-responsive modulator promoter in human T cells is regulated by protein phosphatase 2A-mediated dephosphorylation of SP-1 and reflects disease activity in patients with systemic lupus erythematosus. J. Biol. Chem. 2011, 286:1795-1801.
    • (2011) J. Biol. Chem. , vol.286 , pp. 1795-1801
    • Juang, Y.T.1    Rauen, T.2    Wang, Y.3
  • 32
    • 0033696277 scopus 로고    scopus 로고
    • Novel cyclic adenosine 3',5'-monophosphate (cAMP) response element modulator theta isoforms expressed by two newly identified cAMP-responsive promoters active in the testis
    • Daniel P.B., Rohrbach L., Habener J.F. Novel cyclic adenosine 3',5'-monophosphate (cAMP) response element modulator theta isoforms expressed by two newly identified cAMP-responsive promoters active in the testis. Endocrinology 2000, 141:3923-3930.
    • (2000) Endocrinology , vol.141 , pp. 3923-3930
    • Daniel, P.B.1    Rohrbach, L.2    Habener, J.F.3
  • 33
  • 34
    • 0032858430 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells
    • Platzer C., Fritsch E., Elsner T., et al. Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells. Eur. J. Immunol. 1999, 29:3098-3104.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3098-3104
    • Platzer, C.1    Fritsch, E.2    Elsner, T.3
  • 35
    • 0035971436 scopus 로고    scopus 로고
    • Partners in transcription: NFAT and AP-1
    • Macián F., López-Rodríguez C., Rao A. Partners in transcription: NFAT and AP-1. Oncogene 2001, 20:2476-2489.
    • (2001) Oncogene , vol.20 , pp. 2476-2489
    • Macián, F.1    López-Rodríguez, C.2    Rao, A.3
  • 36
    • 0027762590 scopus 로고
    • The mechanism of action of FK-506 and cyclosporin A
    • Wiederrecht G., Lam E., Hung S., et al. The mechanism of action of FK-506 and cyclosporin A. Ann. N. Y. Acad. Sci. 1993, 696:9-19.
    • (1993) Ann. N. Y. Acad. Sci. , vol.696 , pp. 9-19
    • Wiederrecht, G.1    Lam, E.2    Hung, S.3
  • 37
    • 0027214508 scopus 로고
    • Transcriptional regulation by CREB and its relatives
    • Lee K.A., Masson N. Transcriptional regulation by CREB and its relatives. Biochim. Biophys. Acta 1993, 1174:221-223.
    • (1993) Biochim. Biophys. Acta , vol.1174 , pp. 221-223
    • Lee, K.A.1    Masson, N.2
  • 38
    • 16844376445 scopus 로고    scopus 로고
    • Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV
    • Juang Y.T., Wang Y., Solomou E.E., et al. Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV. J. Clin. Invest. 2005, 115:996-1005.
    • (2005) J. Clin. Invest. , vol.115 , pp. 996-1005
    • Juang, Y.T.1    Wang, Y.2    Solomou, E.E.3
  • 39
    • 33845994433 scopus 로고    scopus 로고
    • CAMP response element modulator α expression in patients with systemic lupus erythematosus
    • Kyttaris V.C., Wang Y., Juang Y.T., et al. CAMP response element modulator α expression in patients with systemic lupus erythematosus. Lupus 2006, 15:840-844.
    • (2006) Lupus , vol.15 , pp. 840-844
    • Kyttaris, V.C.1    Wang, Y.2    Juang, Y.T.3
  • 40
    • 0032759619 scopus 로고    scopus 로고
    • The -180 site of the IL-2 promoter is the target of CREB/CREM binding in T cell anergy
    • Powell J.D., Lerner C.G., Ewoldt G.R., et al. The -180 site of the IL-2 promoter is the target of CREB/CREM binding in T cell anergy. J. Immunol. 1999, 163:6631-6639.
    • (1999) J. Immunol. , vol.163 , pp. 6631-6639
    • Powell, J.D.1    Lerner, C.G.2    Ewoldt, G.R.3
  • 41
    • 0032852479 scopus 로고    scopus 로고
    • CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • Shaywitz A.J., Greenberg M.E. CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu. Rev. Biochem. 1999, 68:821-861.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 42
    • 0037108487 scopus 로고    scopus 로고
    • Antisense cyclic adenosine 5'-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus
    • Tenbrock K., Juang Y.T., Gourley M.F., et al. Antisense cyclic adenosine 5'-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus. J. Immunol. 2002, 169:4147-4152.
    • (2002) J. Immunol. , vol.169 , pp. 4147-4152
    • Tenbrock, K.1    Juang, Y.T.2    Gourley, M.F.3
  • 43
    • 0037443547 scopus 로고    scopus 로고
    • The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism
    • Tenbrock K., Juang Y.T., Tolnay M., et al. The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism. J. Immunol. 2003, 170:2971-2976.
    • (2003) J. Immunol. , vol.170 , pp. 2971-2976
    • Tenbrock, K.1    Juang, Y.T.2    Tolnay, M.3
  • 44
    • 0029864398 scopus 로고    scopus 로고
    • Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells. Convergence of costimulatory signals and differences from transformed T cells
    • Hughes C.C., Pober J.S. Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells. Convergence of costimulatory signals and differences from transformed T cells. J. Biol. Chem. 1996, 271:5369-5377.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5369-5377
    • Hughes, C.C.1    Pober, J.S.2
  • 45
    • 79952291184 scopus 로고    scopus 로고
    • Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)
    • Vaeth M., Gogishvili T., Bopp T., et al. Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1). Proc. Natl. Acad. Sci. USA 2011, 108:2480-2485.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2480-2485
    • Vaeth, M.1    Gogishvili, T.2    Bopp, T.3
  • 46
    • 54949131682 scopus 로고    scopus 로고
    • Modulation of peripheral B cell tolerance by CD72 in a murine model
    • Li D.H., Winslow M.M., Cao T.M., et al. Modulation of peripheral B cell tolerance by CD72 in a murine model. Arthritis Rheum. 2008, 58:192-204.
    • (2008) Arthritis Rheum. , vol.58 , pp. 192-204
    • Li, D.H.1    Winslow, M.M.2    Cao, T.M.3
  • 47
    • 0028238472 scopus 로고
    • Targeted mutation of the CREB gene: Compensation within the CREB/ATF family of transcription factors
    • Hummler E., Cole T.J., Blendy J.A., et al. Targeted mutation of the CREB gene: Compensation within the CREB/ATF family of transcription factors. Proc. Natl. Acad. Sci. USA 1994, 91:5647-5651.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5647-5651
    • Hummler, E.1    Cole, T.J.2    Blendy, J.A.3
  • 48
    • 0025871709 scopus 로고
    • A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus
    • Tada Y., Nagasawa K., Yamauchi Y., et al. A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus. Clin. Immunol. Immunopathol. 1991, 60:220-231.
    • (1991) Clin. Immunol. Immunopathol. , vol.60 , pp. 220-231
    • Tada, Y.1    Nagasawa, K.2    Yamauchi, Y.3
  • 49
    • 0037289364 scopus 로고    scopus 로고
    • Defective activity of ERK-1 and ERK-2 mitogen-activated protein kinases in peripheral blood T lymphocytes from patients with systemic lupus erythematosus: Potential role of altered coupling of Ras guanine nucleotide exchange factor hSos to adapter protein Grb2 in lupus T cells
    • Cedeño S., Cifarelli D.F., Blasini A.M., et al. Defective activity of ERK-1 and ERK-2 mitogen-activated protein kinases in peripheral blood T lymphocytes from patients with systemic lupus erythematosus: Potential role of altered coupling of Ras guanine nucleotide exchange factor hSos to adapter protein Grb2 in lupus T cells. Clin. Immunol. 2003, 106:41-49.
    • (2003) Clin. Immunol. , vol.106 , pp. 41-49
    • Cedeño, S.1    Cifarelli, D.F.2    Blasini, A.M.3
  • 50
    • 0036291454 scopus 로고    scopus 로고
    • Deficient protein kinase A in systemic lupus erythematosus: A disorder of T lymphocyte signal transduction
    • Kammer G.M. Deficient protein kinase A in systemic lupus erythematosus: A disorder of T lymphocyte signal transduction. Ann. N. Y. Acad. Sci. 2002, 968:96-105.
    • (2002) Ann. N. Y. Acad. Sci. , vol.968 , pp. 96-105
    • Kammer, G.M.1
  • 51
    • 0026009532 scopus 로고
    • Transcriptional antagonist cAMP-responsive element modulator (CREM) down-regulates c-fos cAMP-induced expression
    • Foulkes N.S., Laoide B.M., Schlotter F., et al. Transcriptional antagonist cAMP-responsive element modulator (CREM) down-regulates c-fos cAMP-induced expression. Proc. Natl. Acad. Sci. USA 1991, 88:5448-5452.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5448-5452
    • Foulkes, N.S.1    Laoide, B.M.2    Schlotter, F.3
  • 52
    • 0026624810 scopus 로고
    • Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts
    • Trabandt A., Aicher W.K., Gay R.E., et al. Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts. Rheumatol. Int. 1992, 12:53-59.
    • (1992) Rheumatol. Int. , vol.12 , pp. 53-59
    • Trabandt, A.1    Aicher, W.K.2    Gay, R.E.3
  • 53
    • 0037466491 scopus 로고    scopus 로고
    • P21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients
    • Hikasa M., Yamamoto E., Kawasaki H., et al. P21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients. Biochem. Biophys. Res. Commun. 2003, 304:143-147.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , pp. 143-147
    • Hikasa, M.1    Yamamoto, E.2    Kawasaki, H.3
  • 54
    • 0032428729 scopus 로고    scopus 로고
    • AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis
    • Han Z., Boyle D.L., Manning A.M., et al. AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 1998, 28:197-208.
    • (1998) Autoimmunity , vol.28 , pp. 197-208
    • Han, Z.1    Boyle, D.L.2    Manning, A.M.3
  • 55
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain
    • Liossis S.N., Ding X.Z., Dennis G.J., et al. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J. Clin. Invest. 1998, 101:1448-1457.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3
  • 56
    • 0035157041 scopus 로고    scopus 로고
    • Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB
    • Asahara H., Santoso B., Guzman E., et al. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Mol. Cell. Biol. 2001, 21:7892-7900.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7892-7900
    • Asahara, H.1    Santoso, B.2    Guzman, E.3
  • 57
    • 33750370863 scopus 로고    scopus 로고
    • The transcriptional repressor cAMP response element modulator α interacts with histone deacetylase 1 to repress promoter activity
    • Tenbrock K., Juang Y.T., Leukert N., et al. The transcriptional repressor cAMP response element modulator α interacts with histone deacetylase 1 to repress promoter activity. J. Immunol. 2006, 177:6159-6164.
    • (2006) J. Immunol. , vol.177 , pp. 6159-6164
    • Tenbrock, K.1    Juang, Y.T.2    Leukert, N.3
  • 58
    • 0037330279 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
    • Mishra N., Reilly C.M., Brown D.R., et al. Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. J. Clin. Invest. 2003, 111:539-552.
    • (2003) J. Clin. Invest. , vol.111 , pp. 539-552
    • Mishra, N.1    Reilly, C.M.2    Brown, D.R.3
  • 59
    • 77953288009 scopus 로고    scopus 로고
    • Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells
    • Zhao M., Sun Y., Gao F., et al. Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells. J. Autoimmun. 2010, 35:58-69.
    • (2010) J. Autoimmun. , vol.35 , pp. 58-69
    • Zhao, M.1    Sun, Y.2    Gao, F.3
  • 60
    • 15444377542 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription
    • Lu Z.P., Ju Z.L., Sh G.Y., et al. Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription. Biochem. Biophys. Res. Commun. 2005, 330:204-209.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 204-209
    • Lu, Z.P.1    Ju, Z.L.2    Sh, G.Y.3
  • 61
    • 64249090036 scopus 로고    scopus 로고
    • The cyclic AMP response element modulator alpha suppresses CD86 expression and APC function
    • Ahlmann M., Varga G., Sturm K., et al. The cyclic AMP response element modulator alpha suppresses CD86 expression and APC function. J. Immunol. 2009, 182:4167-4174.
    • (2009) J. Immunol. , vol.182 , pp. 4167-4174
    • Ahlmann, M.1    Varga, G.2    Sturm, K.3
  • 62
    • 0030821695 scopus 로고    scopus 로고
    • Lymphocytes, cytokines, inflammation, and immune trafficking
    • Tsokos G.C., Kovacs B., Liossis S.N. Lymphocytes, cytokines, inflammation, and immune trafficking. Curr. Opin. Rheumatol. 1997, 9:380-386.
    • (1997) Curr. Opin. Rheumatol. , vol.9 , pp. 380-386
    • Tsokos, G.C.1    Kovacs, B.2    Liossis, S.N.3
  • 63
    • 0037446543 scopus 로고    scopus 로고
    • The FcR gamma subunit and SYK kinase replace the CD3 zeta-chain and ZAP-70 kinase in the TCR signaling complex of human effector CD4 T cells
    • Krishnan S., Warke V.G., Nambiar M.P., et al. The FcR gamma subunit and SYK kinase replace the CD3 zeta-chain and ZAP-70 kinase in the TCR signaling complex of human effector CD4 T cells. J. Immunol. 2003, 170:4189-4195.
    • (2003) J. Immunol. , vol.170 , pp. 4189-4195
    • Krishnan, S.1    Warke, V.G.2    Nambiar, M.P.3
  • 64
    • 71849102938 scopus 로고    scopus 로고
    • Differential expression and molecular associations of SYK in systemic lupus erythematosus T cells
    • Krishnan S., Juang Y.T., Chowdhury B., et al. Differential expression and molecular associations of SYK in systemic lupus erythematosus T cells. J. Immunol. 2008, 181:8145-8152.
    • (2008) J. Immunol. , vol.181 , pp. 8145-8152
    • Krishnan, S.1    Juang, Y.T.2    Chowdhury, B.3
  • 65
    • 77954229590 scopus 로고    scopus 로고
    • Suppression of skin and kidney disease by inhibition of spleen tyrosine kinase in lupus-prone mice
    • Deng G.M., Liu L., Bahjat F.R., et al. Suppression of skin and kidney disease by inhibition of spleen tyrosine kinase in lupus-prone mice. Arthritis Rheum. 2010, 62:2086-2092.
    • (2010) Arthritis Rheum. , vol.62 , pp. 2086-2092
    • Deng, G.M.1    Liu, L.2    Bahjat, F.R.3
  • 66
    • 84857760849 scopus 로고    scopus 로고
    • CREMα suppresses spleen tyrosine kinase expression in normal but not in SLE T cells
    • Ghosh D., Kis-Toth K., Juang Y.T., et al. CREMα suppresses spleen tyrosine kinase expression in normal but not in SLE T cells. Arthritis Rheum. 2012, 64:799-807.
    • (2012) Arthritis Rheum. , vol.64 , pp. 799-807
    • Ghosh, D.1    Kis-Toth, K.2    Juang, Y.T.3
  • 67
    • 0026071499 scopus 로고
    • CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription
    • Foulkes N.S., Borrelli E., Sassone-Corsi P. CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 1991, 64:739-749.
    • (1991) Cell , vol.64 , pp. 739-749
    • Foulkes, N.S.1    Borrelli, E.2    Sassone-Corsi, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.