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Volumn 18, Issue 1, 1998, Pages 27-39

Immune cell signaling aberrations in human lupus

Author keywords

Antigen receptor; Costimulation; Human autoimmunity; Lymphocytes; Signal transduction; Systemic lupus erythematosus

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CELL SURFACE RECEPTOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLYCOPROTEIN GP 39;

EID: 0031710196     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786511     Document Type: Review
Times cited : (23)

References (70)
  • 1
    • 0003262391 scopus 로고
    • Overview of cellular immune function in systemic lupus erythematosus
    • Lahita RG (ed): New York, NY, Churchill Livingstone
    • Tsokos GC. Overview of cellular immune function in systemic lupus erythematosus;in Lahita RG (ed): Systemic Lupus Erythematosus. New York, NY, Churchill Livingstone, 1992, pp 15-50.
    • (1992) Systemic Lupus Erythematosus , pp. 15-50
    • Tsokos, G.C.1
  • 3
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994;76:263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 4
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco AL. The complexity of signaling pathways activated by the BCR. Curr Opin Immunol 1997;9:296-308.
    • (1997) Curr Opin Immunol , vol.9 , pp. 296-308
    • DeFranco, A.L.1
  • 5
    • 0028346563 scopus 로고
    • Signal transduction by the B cell receptor and its coreceptors
    • Cambier JC, Pleiman CM, Clark MR. Signal transduction by the B cell receptor and its coreceptors. Annu Rev Immunol 1994;12:457-486.
    • (1994) Annu Rev Immunol , vol.12 , pp. 457-486
    • Cambier, J.C.1    Pleiman, C.M.2    Clark, M.R.3
  • 6
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth M. Antigen receptor tail clue. Nature (Lond) 1989;338:383-384.
    • (1989) Nature (Lond) , vol.338 , pp. 383-384
    • Reth, M.1
  • 7
    • 0026729146 scopus 로고
    • Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-g2 in B lymphocytes
    • Coggeshall KM, McHugh JC, Altman A. Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-g2 in B lymphocytes. Proc Natl Acad Sci USA 1992; 89:5660-5664.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5660-5664
    • Coggeshall, K.M.1    McHugh, J.C.2    Altman, A.3
  • 8
    • 0025285280 scopus 로고
    • Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation
    • June CH, Fletcher MC, Ledbetter JA, Samelson LE. Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation. J Immunol 1990; 144:1591-1599.
    • (1990) J Immunol , vol.144 , pp. 1591-1599
    • June, C.H.1    Fletcher, M.C.2    Ledbetter, J.A.3    Samelson, L.E.4
  • 9
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Wash. DC
    • Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science (Wash. DC) 1992;258: 607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 10
    • 0027397544 scopus 로고    scopus 로고
    • Inositol trisphosphate and calcium signaling
    • Berridge MJ. Inositol trisphosphate and calcium signaling. Nature (Lond) 361:315-325.
    • Nature (Lond) , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 12
    • 0030896612 scopus 로고    scopus 로고
    • Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy
    • Smith JA, Tso JY, Clark MR, Cole MS, Bluestone JA. Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy. J Exp Med 1997;185:1413-1422.
    • (1997) J Exp Med , vol.185 , pp. 1413-1422
    • Smith, J.A.1    Tso, J.Y.2    Clark, M.R.3    Cole, M.S.4    Bluestone, J.A.5
  • 13
    • 0029164734 scopus 로고
    • TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus
    • Vassilopoulos D, Kovacs B, Tsokos GC. TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus. J Immunol 1995; 155:2269-2281.
    • (1995) J Immunol , vol.155 , pp. 2269-2281
    • Vassilopoulos, D.1    Kovacs, B.2    Tsokos, G.C.3
  • 14
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor ζ chain
    • Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor ζ chain. J Clin Invest 1998;101:1448-1457.
    • (1998) J Clin Invest , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 15
    • 0028278214 scopus 로고
    • Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes
    • Kammer GM, Khan I, Malemud C. Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes. J Clin Invest 1994;94:422-430.
    • (1994) J Clin Invest , vol.94 , pp. 422-430
    • Kammer, G.M.1    Khan, I.2    Malemud, C.3
  • 16
    • 0025871709 scopus 로고
    • A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus
    • Tada Y, Nagasawa K, Yamauchi Y, Tsukamoto H, Niho Y. A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1991;60: 220-231.
    • (1991) Clin Immunol Immunopathol , vol.60 , pp. 220-231
    • Tada, Y.1    Nagasawa, K.2    Yamauchi, Y.3    Tsukamoto, H.4    Niho, Y.5
  • 17
    • 0031018130 scopus 로고    scopus 로고
    • Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus
    • Portales-Perez D, Gonzalez-Amaro R, Abud-Mentoza C, Sanchez-Armass S. Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus. Lupus 1997;6:48-56.
    • (1997) Lupus , vol.6 , pp. 48-56
    • Portales-Perez, D.1    Gonzalez-Amaro, R.2    Abud-Mentoza, C.3    Sanchez-Armass, S.4
  • 18
    • 0029829026 scopus 로고    scopus 로고
    • B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events
    • Liossis SNC, Kovacs B, Dennis J, Kammer GM, Tsokos GC. B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. J Clin Invest 1996;98:2549-2557.
    • (1996) J Clin Invest , vol.98 , pp. 2549-2557
    • Liossis, S.N.C.1    Kovacs, B.2    Dennis, J.3    Kammer, G.M.4    Tsokos, G.C.5
  • 19
    • 0026587743 scopus 로고
    • CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
    • Carter RH, Fearon DT. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 1992;256:105-107.
    • (1992) Science , vol.256 , pp. 105-107
    • Carter, R.H.1    Fearon, D.T.2
  • 20
    • 0022646588 scopus 로고
    • Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus
    • Wilson JG, Ratnoff WD, Schur PH, Fearon DT. Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus. Arthritis Rheum 1986;29:739-747.
    • (1986) Arthritis Rheum , vol.29 , pp. 739-747
    • Wilson, J.G.1    Ratnoff, W.D.2    Schur, P.H.3    Fearon, D.T.4
  • 21
    • 0029014256 scopus 로고
    • Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE)
    • Marquart HV, Svendsen A, Rasmussen JM, Niesen CH, Junker P, Svehag SE, Leslie RG. Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 1995;101:60-65.
    • (1995) Clin Exp Immunol , vol.101 , pp. 60-65
    • Marquart, H.V.1    Svendsen, A.2    Rasmussen, J.M.3    Niesen, C.H.4    Junker, P.5    Svehag, S.E.6    Leslie, R.G.7
  • 22
    • 0028347321 scopus 로고
    • A 13-amino-acid motif in the cytoplasmic domain of FcgRIIB modulates B-cell receptor signalling
    • Muta T, Kurosaki T, Misulovin Z, Sanchez M, Nussenzweig MC, Ravetch JV. A 13-amino-acid motif in the cytoplasmic domain of FcgRIIB modulates B-cell receptor signalling. Nature 1994; 368:70-73.
    • (1994) Nature , vol.368 , pp. 70-73
    • Muta, T.1    Kurosaki, T.2    Misulovin, Z.3    Sanchez, M.4    Nussenzweig, M.C.5    Ravetch, J.V.6
  • 25
    • 0028961264 scopus 로고
    • Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
    • Cyster JG, Goodnow CC.Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 1995;2:13-24.
    • (1995) Immunity , vol.2 , pp. 13-24
    • Cyster, J.G.1    Goodnow, C.C.2
  • 26
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcgRIIB
    • Ono M, Boland S, Tempst P, Ravetch JV.Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcgRIIB. Nature 1996;383:263-266.
    • (1996) Nature , vol.383 , pp. 263-266
    • Ono, M.1    Boland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 27
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in FcgRII-deficient mice
    • Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV.Augmented humoral and anaphylactic responses in FcgRII-deficient mice. Nature 1996;379:346-349.
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 31
    • 0030839580 scopus 로고    scopus 로고
    • Increased expression of functional Fas ligand in activated T cells from patients with systemic lupus erythematosus
    • In press
    • Kovacs B, Liossis SNC, Dennis JG, Tsokos GC. Increased expression of functional Fas ligand in activated T cells from patients with systemic lupus erythematosus. Autoimmunity 1997;In press.
    • (1997) Autoimmunity
    • Kovacs, B.1    Liossis, S.N.C.2    Dennis, J.G.3    Tsokos, G.C.4
  • 32
    • 0019948507 scopus 로고
    • Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus
    • Alcocer-Varela J, Alarcon-Segovia D. Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus. J Clin Invest 1982;69: 1388-1392.
    • (1982) J Clin Invest , vol.69 , pp. 1388-1392
    • Alcocer-Varela, J.1    Alarcon-Segovia, D.2
  • 33
    • 0026476032 scopus 로고
    • CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation
    • Noelle RJ, Ledbetter JA, Aruffo A. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol Today 1992;13:431-433.
    • (1992) Immunol Today , vol.13 , pp. 431-433
    • Noelle, R.J.1    Ledbetter, J.A.2    Aruffo, A.3
  • 36
    • 0026075276 scopus 로고
    • Stimulation of B-cells via the membrane immunoglobulin receptor or with phorbol myristate 13-acetate induces tyrosine phosphorylation and activation of a 42 kDa microtubule-associated protein-2 kinase
    • Cassilas A, Hanekom C, Williams K, Katz R, Nel AE. Stimulation of B-cells via the membrane immunoglobulin receptor or with phorbol myristate 13-acetate induces tyrosine phosphorylation and activation of a 42 kDa microtubule-associated protein-2 kinase. J Biol Chem 1991;266:19,088-19,094.
    • (1991) J Biol Chem , vol.266 , pp. 19088-19094
    • Cassilas, A.1    Hanekom, C.2    Williams, K.3    Katz, R.4    Nel, A.E.5
  • 37
    • 0030586679 scopus 로고    scopus 로고
    • CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells
    • Li YY, Baccam M, Waters SB, Pessin JE, Bishop GA, Koretzky GA. CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells. J Immunol 1996;157:1440-1447.
    • (1996) J Immunol , vol.157 , pp. 1440-1447
    • Li, Y.Y.1    Baccam, M.2    Waters, S.B.3    Pessin, J.E.4    Bishop, G.A.5    Koretzky, G.A.6
  • 38
    • 0030587829 scopus 로고    scopus 로고
    • Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell receptor
    • Sutherland CL, Heath AW, Pelech SL, Young PR, Gold MR. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell receptor. J Immunol 1996; 157:3381-3390.
    • (1996) J Immunol , vol.157 , pp. 3381-3390
    • Sutherland, C.L.1    Heath, A.W.2    Pelech, S.L.3    Young, P.R.4    Gold, M.R.5
  • 39
    • 0029862164 scopus 로고    scopus 로고
    • Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes
    • Koshy M, Berger D, Crow MK. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J Clin Invest 1996;98:826-837.
    • (1996) J Clin Invest , vol.98 , pp. 826-837
    • Koshy, M.1    Berger, D.2    Crow, M.K.3
  • 41
    • 0029913381 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production
    • Desai-Mehta A, Lu L, Ramsey-Goldman R, Datta SK. Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 1996; 97:2063-2073.
    • (1996) J Clin Invest , vol.97 , pp. 2063-2073
    • Desai-Mehta, A.1    Lu, L.2    Ramsey-Goldman, R.3    Datta, S.K.4
  • 42
    • 0026320526 scopus 로고
    • Tumor necrosis factor (TNF) receptor family expression in T lymphocytes. Differential regulation of the type 1 TNF receptor during activation of resting and effector T cells
    • Ware CF, Crowe PD, Vanarsdale TL, Grayson MH, Jerzy R, Smith CA, Goodwin RG. Tumor necrosis factor (TNF) receptor family expression in T lymphocytes. Differential regulation of the type 1 TNF receptor during activation of resting and effector T cells. J Immunol 1991;147:4229-4238.
    • (1991) J Immunol , vol.147 , pp. 4229-4238
    • Ware, C.F.1    Crowe, P.D.2    Vanarsdale, T.L.3    Grayson, M.H.4    Jerzy, R.5    Smith, C.A.6    Goodwin, R.G.7
  • 43
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 1994;77:727-736.
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 44
    • 0027816953 scopus 로고
    • Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40
    • Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA, Noelle RJ. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 1993;261:1328-1330.
    • (1993) Science , vol.261 , pp. 1328-1330
    • Durie, F.H.1    Fava, R.A.2    Foy, T.M.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 46
    • 0029862933 scopus 로고    scopus 로고
    • The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells
    • Griggs ND, Agersborg SS, Noelle RJ, Ledbetter JA, Linsley PS, Tung KS. The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells. J Exp Med 1996; 183:801-810.
    • (1996) J Exp Med , vol.183 , pp. 801-810
    • Griggs, N.D.1    Agersborg, S.S.2    Noelle, R.J.3    Ledbetter, J.A.4    Linsley, P.S.5    Tung, K.S.6
  • 47
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan C, Shi Y, Laman JD, Datta SK. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol 1995;154:1470-1480.
    • (1995) J Immunol , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 49
    • 0031091743 scopus 로고    scopus 로고
    • Is CTLA-4 a master switch for peripheral T cell tolerance?
    • Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol 1997;158: 1989-1993.
    • (1997) J Immunol , vol.158 , pp. 1989-1993
    • Bluestone, J.A.1
  • 50
    • 0030910133 scopus 로고    scopus 로고
    • Expression of CD28, CTLA4, CD80, and CD86 molecules in patients with autoimmune rheumatic diseases
    • Sfikakis PP, Via CS. Expression of CD28, CTLA4, CD80, and CD86 molecules in patients with autoimmune rheumatic diseases. Clin Immunol Immunopathol 1997;83:195-198.
    • (1997) Clin Immunol Immunopathol , vol.83 , pp. 195-198
    • Sfikakis, P.P.1    Via, C.S.2
  • 52
    • 0029841476 scopus 로고    scopus 로고
    • Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis
    • Kaneko H, Saito K, Hashimoto H, Yagita H, Okumura K, Azuma M. Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis. Clin Exp Immunol 1996;106: 218-229.
    • (1996) Clin Exp Immunol , vol.106 , pp. 218-229
    • Kaneko, H.1    Saito, K.2    Hashimoto, H.3    Yagita, H.4    Okumura, K.5    Azuma, M.6
  • 53
    • 0028238287 scopus 로고
    • B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with Systemic Lupus Erythematosus
    • Sfikakis PP, Oglesby R, Sfikakis P, Tsokos GC. B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with Systemic Lupus Erythematosus. Clin Exp Immunol 1994;96:8-13.
    • (1994) Clin Exp Immunol , vol.96 , pp. 8-13
    • Sfikakis, P.P.1    Oglesby, R.2    Sfikakis, P.3    Tsokos, G.C.4
  • 55
    • 0029060507 scopus 로고
    • Antigen-presenting T cells induce the development of cytotoxic CD4+ T cells
    • Mauri D, Wyss-Coray T, Gallati H, Pichler WJ. Antigen-presenting T cells induce the development of cytotoxic CD4+ T cells. J Immunol 1995;155:118-127.
    • (1995) J Immunol , vol.155 , pp. 118-127
    • Mauri, D.1    Wyss-Coray, T.2    Gallati, H.3    Pichler, W.J.4
  • 56
    • 17644434779 scopus 로고    scopus 로고
    • Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients
    • Folzenlogen D, Hofer MF, Leung DYM, Freed JH, Newell MK. Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol 1997;83:199-204.
    • (1997) Clin Immunol Immunopathol , vol.83 , pp. 199-204
    • Folzenlogen, D.1    Hofer, M.F.2    Leung, D.Y.M.3    Freed, J.H.4    Newell, M.K.5
  • 57
    • 0030265644 scopus 로고    scopus 로고
    • B7 costimulation and autoantigen-speciftcity enable B cells to activate autoreactive T cells
    • Roth R, Nakamura T, Mamula MJ. B7 costimulation and autoantigen-speciftcity enable B cells to activate autoreactive T cells. J Immunol 1996;157:2924-2931.
    • (1996) J Immunol , vol.157 , pp. 2924-2931
    • Roth, R.1    Nakamura, T.2    Mamula, M.J.3
  • 58
    • 0029929607 scopus 로고    scopus 로고
    • Defective antigen-presenting cell function in patients with systemic lupus erythematosus. Role of the B7-1 (CD80) costimulatory molecule
    • Tsokos GC, Kovacs B, Sfikakis PP, Theocharis S, Vogelgesang S, Via CS. Defective antigen-presenting cell function in patients with systemic lupus erythematosus. Role of the B7-1 (CD80) costimulatory molecule. Arthritis Rheum 1996;39:600-609.
    • (1996) Arthritis Rheum , vol.39 , pp. 600-609
    • Tsokos, G.C.1    Kovacs, B.2    Sfikakis, P.P.3    Theocharis, S.4    Vogelgesang, S.5    Via, C.S.6
  • 60
    • 1842299353 scopus 로고    scopus 로고
    • Decreased T cell response to anti-CD2 in systemic lupus erythematosus and reversal by anti-CD28
    • Horwitz DA, Tang FL, Stimmler MM, Oki A, Gray JD. Decreased T cell response to anti-CD2 in systemic lupus erythematosus and reversal by anti-CD28. Arthritis Rheum 1997;40:822-833.
    • (1997) Arthritis Rheum , vol.40 , pp. 822-833
    • Horwitz, D.A.1    Tang, F.L.2    Stimmler, M.M.3    Oki, A.4    Gray, J.D.5
  • 61
    • 0010303486 scopus 로고
    • Expression of the CD80 (B7/BB1) T cell costimulatory molecule in the skin of patients with systemic sclerosis
    • Sfikakis PP, Anagnostopoulos J. Karameris A et al. Expression of the CD80 (B7/BB1) T cell costimulatory molecule in the skin of patients with systemic sclerosis. Arthritis Rheum 1994;37(suppl 9), S 265.
    • (1994) Arthritis Rheum , vol.37 , Issue.9 SUPPL.
    • Sfikakis, P.P.1    Anagnostopoulos, J.2    Karameris, A.3
  • 62
    • 0030904858 scopus 로고    scopus 로고
    • In situ expression of B7 and CD28 receptor families in skin lesions of patients with lupus erythematosus
    • Denfeld RW, Kind P, Sontheimer RD, Schopf E, Simon JC. In situ expression of B7 and CD28 receptor families in skin lesions of patients with lupus erythematosus. Arthritis Rheum 1997;40:814-821.
    • (1997) Arthritis Rheum , vol.40 , pp. 814-821
    • Denfeld, R.W.1    Kind, P.2    Sontheimer, R.D.3    Schopf, E.4    Simon, J.C.5
  • 63
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4Ig. Science 1994;265: 1225-1227.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 64
    • 0028919313 scopus 로고
    • The basis of autoimmunity:Part II Genetic predisposition
    • Theofilopoulos AN. The basis of autoimmunity:Part II Genetic predisposition. Immunol Today 1995;16:150-159.
    • (1995) Immunol Today , vol.16 , pp. 150-159
    • Theofilopoulos, A.N.1
  • 65
    • 0028316937 scopus 로고
    • Genetic analysis of the NZB contribution to lupus-like renal disease:multiple genes that operate in a threshold manner
    • Drake CG, Babcock SK, Palmer E, Kotzin BL. Genetic analysis of the NZB contribution to lupus-like renal disease:multiple genes that operate in a threshold manner. Proc Natl Acad Sci USA 1994; 91:4062-4066.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4062-4066
    • Drake, C.G.1    Babcock, S.K.2    Palmer, E.3    Kotzin, B.L.4
  • 68
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis. Sle2 on murine chromosome 4 leads to B cell hyperactivity
    • Mohan C, Morel L, Yang P, Wakeland EK. Genetic dissection of systemic lupus erythematosus pathogenesis. Sle2 on murine chromosome 4 leads to B cell hyperactivity. J Immunol 1997; 159:454-465.
    • (1997) J Immunol , vol.159 , pp. 454-465
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 69
    • 0031570375 scopus 로고    scopus 로고
    • Functional dissection of systemic lupus erythematosus using congenic mouse strains
    • Morel L, Mohan C, Yu Y, Croker BP, Tian N, Deng A, Wakeland EK. Functional dissection of systemic lupus erythematosus using congenic mouse strains. J Immunol 1997;158:6019-6028.
    • (1997) J Immunol , vol.158 , pp. 6019-6028
    • Morel, L.1    Mohan, C.2    Yu, Y.3    Croker, B.P.4    Tian, N.5    Deng, A.6    Wakeland, E.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.