Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias

APMIS

Volumn 115, Issue 12, 2007, Pages 1357-1363

  Lee, Sung Hak ^a   Jeong, Eun Goo ^a   Yoo, Nam Jin ^a   Lee, Sug Hyung ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Leukaemia; Mutation; NOTCH; Solid cancers

Indexed keywords

NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; B CELL LEUKEMIA; BREAST CARCINOMA; CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INCIDENCE; LUNG CARCINOMA; NOTCH1 GENE; NOTCH2 GENE; NOTCH3 GENE; NOTCH4 GENE; PATHOGENESIS; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SOLID TUMOR; SOMATIC MUTATION; STOMACH CARCINOMA; T CELL LEUKEMIA;

ADULT; AGED; AGED, 80 AND OVER; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; HUMANS; MIDDLE AGED; MUTATION; NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; RECEPTORS, NOTCH;

EID: 37549059579     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2007.00751.x     Document Type: Article

References (27)

1. Leong KG, Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 2006 107: 2223 33.
2. Mumm JS, Kopan R. Notch signaling: from the outside in. Dev Biol 2000 228: 151 65.
3. Lai EC. Notch signaling: control of cell communication and cell fate. Development 2004 131: 965 73.
4. Miyamoto Y, Maitra A, Ghosh B, Zechner U, Argani P, Iacobuzio-Donahue CA, et al. Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 2003 3: 565 76.
5. Santagata S, Demichelis F, Riva A, Varambally S, Hofer MD, Kutok JL, et al. JAGGED1 expression is associated with prostate cancer metastasis and recurrence. Cancer Res 2004 64: 6854 7.
6. Gray GE, Mann RS, Mitsiadis E, Henrique D, Carcangiu ML, Banks A, et al. Human ligands of the Notch receptor. Am J Pathol 1999 154: 785 94.
7. Cuevas IC, Slocum AL, Jun P, Costello JF, Bollen AW, Riggins GJ, et al. Meningioma transcript profiles reveal deregulated Notch signaling pathway. Cancer Res 2005 65: 5070 5.
8. Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 2003 22: 6598 608.
9. Gallahan D, Kozak C, Callahan R. A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J Virol 1987 61: 218 20.
10. Soriano JV, Uyttendaele H, Kitajewski J, Montesano R. Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro. Int J Cancer 2000 86: 652 9.
11. Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med 2002 8: 979 86.
12. Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Olson S, Gonzalez A, et al. Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers. Cancer Res 2005 65: 3555 61.
13. Weng AP, Ferrando AA, Lee W, Morris JP 4th., Silverman LB, Sanchez-Irizarry C, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004 306: 269 71.
14. Mansour MR, Linch DC, Foroni L, Goldstone AH, Gale RE. High incidence of Notch-1 mutations in adult patients with T-cell acute lymphoblastic leukemia. Leukemia 2006 20: 537 9.
15. Lee SH, Shin MS, Park WS, Kim SY, Kim HS, Han JY, et al. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer. Oncogene 1999 18: 3754 60.
16. Soung YH, Lee JW, Kim SY, Park WS, Nam SW, Lee JY, et al. Somatic mutations of CASP3 gene in human cancers. Hum Genet 2004 115: 112 5.
17. Kim HS, Lee JW, Soung YH, Park WS, Kim SY, Lee JH, et al. Inactivating mutations of caspase-8 gene in colorectal carcinomas. Gastroenterology 2003 125: 708 15.
18. Fu L, Kogoshi H, Nara N, Tohda S. NOTCH1 mutations are rare in acute myeloid leukemia. Leuk Lymphoma 2006 47: 2400 3.
19. Palomero T, McKenna K, O'Neil J, Galinsky I, Stone R, Suzukawa K, et al. Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias. Leukemia 2006 20: 1963 6.
20. Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003 3: 459 65.
21. Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004 304: 1497 500.
22. Stephens P, Hunter C, Bignell G, Edkins S, Davies H, Teague J, et al. Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature 2004 431: 525 6.
23. Soung YH, Lee JW, Kim SY, Wang YP, Jo KH, Moon SW, et al. Somatic mutations of the ERBB4 kinase domain in human cancers. Int J Cancer 2006 118: 1426 9.
24. Soung YH, Lee JW, Kim HS, Park WS, Kim SY, Lee JH, et al. Inactivating mutations of CASPASE-7 gene in human cancers. Oncogene 2003 22: 8048 52.
25. Shin MS, Kim HS, Kang CS, Park WS, Kim SY, Lee SN, et al. Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood 2002 99: 4094 9.
26. Malecki MJ, Sanchez-Irizarry C, Mitchell JL, Histen G, Xu ML, Aster JC, et al. Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes. Mol Cell Biol 2006 26: 4642 51.
27. Stryer L. Biochemistry. New York: W. H. Freeman, 1988.