Synthesis and biological activity of derivatives of tetrahydroacridine as acetylcholinesterase inhibitors

Bioorganic Chemistry

Volumn 39, Issue 4, 2011, Pages 138-142

  Szymański, Paweł ^a   Markowicz, Magdalena ^a   Mikiciuk Olasik, Elbieta ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Acetylcholinesterase inhibitors; Alzheimer's disease; HYNIC

Indexed keywords

6 HYDRAZINO N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]NICOTINAMIDE; 6 HYDRAZINO N [5 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)PENTYL]NICOTINAMIDE; 6 HYDRAZINO N [7 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEPTYL]NICOTINAMIDE; 6 HYDRAZINO N [9 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)NONYL]NICOTINAMIDE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; HYDRAZINE DERIVATIVE; HYDRAZINE NICOTINATE MOIETY; TACRINE 6 HYDRAZINONICOTINAMIDE; TACRINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ACETYLCHOLINESTERASE; ACRIDINES; ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; ENZYME ACTIVATION; HUMANS; KINETICS; NIACIN; TACRINE;

EID: 80053054004     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2011.05.001     Document Type: Article

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