Downmodulation of CXCL8/IL-8 receptors on neutrophils after recruitment in the airways

Journal of Allergy and Clinical Immunology

Volumn 115, Issue 1, 2005, Pages 88-94

  Pignatti, Patrizia ^a,e   Moscato, Gianna ^a   Casarini, Simona ^a   Delmastro, Monica ^b   Poppa, Mariangela ^a   Brunetti, Giuseppe ^b   Pisati, Paolo ^c   Balbi, Bruno ^d  

^a Serv Autonomo Allergologia I   (Italy)

^b Divisione di Pneumologia

^c Istituto Scientifico di Pavia   (Italy)

^d Istituto Scientifico di Gussago   (Italy)

^e IRCCS   (Italy)

Author keywords

Asthma; chronic obstructive pulmonary disease; CXC chemokine receptor 1; CXC chemokine receptor 2; CXCL8 IL 8; neutrophils

Indexed keywords

CD11B ANTIGEN; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; INTERLEUKIN 8 RECEPTOR;

ADOLESCENT; ADULT; AIRWAY; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPUTUM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD11; ASTHMA; DOWN-REGULATION; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; SPUTUM;

EID: 11344284971     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.08.048     Document Type: Article

References (29)

1. Wuyts A, Proost P, Van Damme J. Interleukin-8 and other CXC chemo- kines. In: Thomson A, editor. The cytokine handbook; 1998. p. 271-311.
2. W.E. Holmes, J. Lee, W.J. Kuang, G.C. Rice, and W.I. Wood Structure and functional expression of a human interleukin-8 receptor Science 253 1991 1278 1280
3. M. Wolf, M.B. Delgado, S.A. Jones, B. Dewald, I. Clark-Lewis, and M. Baggiolini Granulocyte chemotactic protein 2 acts via both CXCL8/IL-8 receptors, CXCR1 and CXCR2 Eur J Immunol 28 1998 164 170
4. A. Jatakanon, C. Uasuf, W. Maziak, S. Lim, K.F. Chung, and P.J. Barnes Neutrophilic inflammation in severe persistent asthma Am J Respir Crit Care Med 160 1999 1532 1539
5. P.G. Gibson, J.L. Simpson, and N. Saltos Heterogeneity of airway inflammation in persistent asthma. Evidence of neutrophilic inflammation and increased sputum interleukin-8 Chest 119 2001 1329 1336
6. S. Sur, T.B. Crotty, G.M. Kephart, B.A. Hyma, T.V. Colby, and C.E. Reed Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis 148 1993 713 719
7. J.V. Fahy, K.W. Kim, J. Liu, and H.A. Boushey Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation J Allergy Clin Immunol 95 1995 843 852
8. S.A. Little, K.J. MacLeod, G.W. Chalmers, J.G. Love, C. McSharry, and N.C. Thomson Association of forced expiratory volume with disease duration and sputum neutrophils in chronic asthma Am J Med 112 2002 446 452
9. S.E. Wenzel, L.B. Schwartz, E.L. Langmack, J.L. Halliday, J.B. Trudeau, and R.L. Gibbs Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics Am J Respir Crit Care Med 160 1999 1001 1008
10. P.L. Podolin, B.J. Bolognese, J.J. Foley, D.B. Schmidt, P.T. Buckley, and K.L. Widdowson A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit J Immunol 169 2002 6435 6444
11. L.F. Zhang X, and J.R. Gordon CXCL8(3-73)K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8 Biochem Biophys Res Commun 293 2002 939 944
12. A. Spanevello, M. Confalonieri, F. Sulotto, F. Romano, G. Balzano, and G.B. Migliori Induced sputum cellularity. Reference values and distribution in normal volunteers Am J Respir Crit Care Med 162 2000 1172 1174
13. R.A. Pauwels, S. Buist, P.M.A. Calverley, C.R. Jenkins, S.S. Hurd, and on behalf of the GOLD Scientific Committee Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease Am J Respir Crit Care Med 163 2001 1256 1276
14. National Asthma Education and Prevention Program Guidelines for the diagnosis and management of Asthma. Expert Panel Report 2 1997 National Institutes of Health, National Heart, Lung, and Blood Institute Bethesda (MD)
15. R. Djukanovic, P. Sterk, J.V. Fahy, and F.E. Hargreave Standardized methodology of sputum induction and processing Eur Respir J 20 suppl 37 2002 1s 55s
16. P. Pignatti, M. Delmastro, L. Perfetti, A. Bossi, A. Balestrino, and A. Di Stefano Is dithiothreitol affecting cells and soluble mediators during sputum processing? A modified methodology to process sputum J Allergy Clin Immunol 110 2002 667 668
17. A.K. Samanta, J.J. Oppenheim, and K. Matsushima Interleukin 8 (monocyte-derived neutrophil chemotactic factor) dynamically regulates its own receptor expression on human neutrophils J Biol Chem 265 1990 183 189
18. A. Chuntharapai, and K.J. Kim Regulation of the expression of CXCL8/IL-8 receptor A/B by CXCL8/IL-8: possible functions of each receptor J Immunol 155 1995 2587 2594
19. M.H. Khandaker, G. Mitchell, L. Xu, J.D. Andrews, R. Singh, and H. Leung Metalloproteinases are involved in lipopolysaccharide-and tumor necrosis factor-α-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression Blood 93 1999 2173 2185
20. C.J. Cummings, T.R. Martin, C.W. Frevert, J.M. Quan, V.A. Wong, and S.M. Mongovin Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis J Immunol 162 1999 2341 2346
21. I. Sabroe, L.R. Prince, E.C. Jones, M.J. Horsburgh, S.J. Foster, and S.N. Vogel Selective roles for toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span J Immunol 170 2003 5268 5275
22. Y. Qiu, J. Zhu, V. Bandi, R.L. Atmar, K. Hattotuwa, and K.K. Guntupalli Biopsy neutrophilia, neutrophil chemokine and receptor gene expression in severe exacerbations of chronic obstructive pulmonary disease Am J Respir Crit Care Med 168 2003 968 975
23. J. Eddleston, S.C. Christiansen, G.R. Jenkins, J.A. Koziol, and B.L. Zuraw Bradykinin increases the in vivo expression of the CXC chemokine receptors CXCR1 and CXCR2 in patients with allergic rhinitis J Allergy Clin Immunol 11 2003 106 112
24. A.J. Mackarel, K.J. Russell, C.S. Brady, M.X. FitzGerald, and C.M. O'Connor Interleukin-8 and leukotriene-B(4), but not formylmethionyl leucylphenylalanine, stimulate CD18-indipendent migration of neutrophils across human pulmonary endothelial cells in vitro Am J Respir Cell Mol Biol 23 2000 154 161
25. D. Qiu, and W.C. Tan Dithiothreitol has a dose-response effect on cell surface antigen expression J Allergy Clin Immunol 103 1999 873 876
26. J. Dauwes, P. Gibson, J. Pekkanen, and N. Pearce Non-eosinophilic asthma: importance and possible mechanisms Thorax 57 2002 643 648
27. G.M. Gauverau, M.D. Inman, M. Kelly, R.M. Watson, S.C. Dorman, and P.M. O'Byrne Increased levels of airway neutrophils reduce the inhibitory effects of inhaled glucocorticosteroids on allergen-induced airway eosinophils Can Respir J 9 2002 26 32
28. M.J. Leckie, A. ten Brinke, J. Khan, Z. Diamant, B.J. O'Connor, and C.M. Walls Effects of an interelukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response Lancet 356 2000 2144 2148
29. L.Y. Liu, J.B. Sedgwick, M.E. Bates, R.F. Vrtis, J.E. Gern, and Kita H Decreased expression of membrane IL-5 receptor α on human eosinophils: I. Loss of membrane IL-5 receptor a on airway eosinophils and increased soluble IL-5 receptor a in the airway after allergen challenge J Immunol 169 2002 6452 6458