Low-dose theophylline does not exert its anti-inflammatory effects in mild asthma through upregulation of interleukin-10 in alveolar macrophages

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 56, Issue 11, 2001, Pages 1087-1090

  Oliver, B ^a   Tomita, K ^a   Keller, A ^b   Caramori, G ^c   Adcock, I ^c   Chung, K F ^c   Barnes, P J ^c   Lim, S ^a,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ALTANA PHARMA AG   (Germany)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d Department of Microbiology and Infectious Diseases   (Australia)

Author keywords

Alveolar macrophages; Asthma; Eosinophils; Interleukin 10; Theophylline

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; SALBUTAMOL; STEROID; THEOPHYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CELL COUNT; CELL CULTURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MECHANISM; EOSINOPHIL; FIBEROPTIC BRONCHOSCOPY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOMODULATION; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RECEPTOR UPREGULATION; T LYMPHOCYTE;

ADULT; ANTI-INFLAMMATORY AGENTS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FORCED EXPIRATORY VOLUME; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-10; MACROPHAGES, ALVEOLAR; MALE; METHACHOLINE CHLORIDE; SEVERITY OF ILLNESS INDEX; THEOPHYLLINE; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0034750233     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2001.00097.x     Document Type: Article

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