Effect of theophylline and specific phosphodiesterase IV inhibition on proliferation and apoptosis of progenitor cells in bronchial asthma

British Journal of Pharmacology

Volumn 138, Issue 6, 2003, Pages 1147-1155

  Wang, Chun Hua ^a   Lin, Horng Chyuan ^a   Lin, Chien Huang ^b   Yu, Chih Teng ^a   Liu, Su Ling ^a   Huang, Kuo Hsiung ^a   Chung, Kian Fan ^c   Kuo, Han Pin ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Asthma; Bcl 2 protein; CD34 + progenitor cells; Phosphodiesterase inhibition; Theophylline

Indexed keywords

BUCLADESINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 5; METHYLCELLULOSE; PHOSPHODIESTERASE IV; ROLIPRAM; SALBUTAMOL; STEM CELL FACTOR; THEOPHYLLINE;

ADULT; APOPTOSIS; ARTICLE; ASTHMA; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL TRIAL; COLONY FORMATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME INHIBITION; EOSINOPHIL; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ALBUTEROL; ANIMALS; ANTIGENS, CD34; APOPTOSIS; ASTHMA; CELL DIVISION; FEMALE; HUMANS; MALE; METHACHOLINE CHLORIDE; PHOSPHODIESTERASE INHIBITORS; ROLIPRAM; STEM CELLS; THEOPHYLLINE; TIME FACTORS;

EID: 0037363621     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705131     Document Type: Article

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