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Volumn 19, Issue 19, 2012, Pages 3103-3127

Antibody-conjugated nanoparticles for therapeutic applications

Author keywords

Active targeting; Antibody conjugated nanoparticles; Infectious diseases therapy; Inflammatory diseases therapy; Surface modification; Targeted drug delivery; Tumour therapy

Indexed keywords

ANTIBODY CONJUGATED NANOPARTICLE; AVIDIN; B LYMPHOCYTE RECEPTOR; BEVACIZUMAB; CANCER ANTIBODY; CD19 ANTIGEN; CETUXIMAB; CHIMERIC ANTIBODY; COPOLYMER; DOXORUBICIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; HLA DR ANTIGEN; IMMUNOGLOBULIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOSOME; MATRIX METALLOPROTEINASE; MONOCLONAL ANTIBODY; NANOCARRIER; NANOPARTICLE; PACLITAXEL; PADGEM PROTEIN; RITUXIMAB; SP1049C; STREPTAVIDIN; TRANSFERRIN; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84863641507     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712800784667     Document Type: Review
Times cited : (106)

References (314)
  • 1
    • 0042922201 scopus 로고
    • Marcel Dekker: New York
    • Kreuter, J. In: Nanoparticles; Marcel Dekker: New York, 1994.
    • (1994) Nanoparticles
    • Kreuter, J.1
  • 3
    • 0037312695 scopus 로고    scopus 로고
    • Nanosizing: A formulation approach for poorly-water-soluble compounds
    • Merisko-Liversidge, E.; Liversidge, G.G.; Cooper, E.R. Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur. J. Pharm. Sci., 2003, 18(2), 113-120.
    • (2003) Eur. J. Pharm. Sci. , vol.18 , Issue.2 , pp. 113-120
    • Merisko-Liversidge, E.1    Liversidge, G.G.2    Cooper, E.R.3
  • 4
    • 33745461665 scopus 로고    scopus 로고
    • Bringing nanomedicines to market: Regulatory challenges, opportunities, and uncertainties
    • Nijhara, R.; Balakrishnan, K. Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties. Nanomedicine, 2006, 2(2), 127-136.
    • (2006) Nanomedicine , vol.2 , Issue.2 , pp. 127-136
    • Nijhara, R.1    Balakrishnan, K.2
  • 5
    • 40949127319 scopus 로고    scopus 로고
    • Therapeutic nanoparticles for drug delivery in cancer
    • Cho, K.J.; Wang, X.; Nie, S.M.; Chen, Z.; Shin, D.M. Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer Res., 2008, 14(5), 1310-1316.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.5 , pp. 1310-1316
    • Cho, K.J.1    Wang, X.2    Nie, S.M.3    Chen, Z.4    Shin, D.M.5
  • 6
    • 42049110950 scopus 로고    scopus 로고
    • Application of nanotechnology in cancer therapy and imaging
    • Wang, X.; Yang, L.L.; Chen, Z.; Shin, D.M. Application of nanotechnology in cancer therapy and imaging. CA Cancer J. Clin., 2008, 58(2), 97-110.
    • (2008) CA Cancer J. Clin. , vol.58 , Issue.2 , pp. 97-110
    • Wang, X.1    Yang, L.L.2    Chen, Z.3    Shin, D.M.4
  • 8
    • 67349179610 scopus 로고    scopus 로고
    • Nanoparticle-based targeted drug delivery
    • Singh, R.; Lillard, J.W. Nanoparticle-based targeted drug delivery. Exp. Mol. Pathol., 2009, 86(3), 215-223.
    • (2009) Exp. Mol. Pathol. , vol.86 , Issue.3 , pp. 215-223
    • Singh, R.1    Lillard, J.W.2
  • 9
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • Moghimi, S.M.; Hunter, A.C.; Murray, J.C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev., 2001, 53(2), 283-318.
    • (2001) Pharmacol. Rev. , vol.53 , Issue.2 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 10
    • 0025109875 scopus 로고
    • Drug targeting in cancer-chemotherapy-a clinical perspective
    • Gupta, P.K. Drug targeting in cancer-chemotherapy-a clinical perspective. J. Pharm. Sci., 1990, 79(11), 949-962.
    • (1990) J. Pharm. Sci. , vol.79 , Issue.11 , pp. 949-962
    • Gupta, P.K.1
  • 11
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • Allen, T.M. Ligand-targeted therapeutics in anticancer therapy. Nat. Rev. Cancer, 2002, 2(10), 750-763.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.10 , pp. 750-763
    • Allen, T.M.1
  • 12
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • Langer, R. Drug delivery and targeting. Nature, 1998, 392(6679), 5-10.
    • (1998) Nature , vol.392 , Issue.6679 , pp. 5-10
    • Langer, R.1
  • 13
    • 0034182386 scopus 로고    scopus 로고
    • Nano and microparticles as controlled drug delivery devices
    • Kumar, M. Nano and microparticles as controlled drug delivery devices. J. Pharm. Pharm. Sci., 2000, 3(2), 234-258.
    • (2000) J. Pharm. Pharm. Sci. , vol.3 , Issue.2 , pp. 234-258
    • Kumar, M.1
  • 14
    • 0034614208 scopus 로고    scopus 로고
    • Microemulsion-based media as novel drug delivery systems
    • Lawrence, M. J.; Rees, G. D. Microemulsion-based media as novel drug delivery systems. Adv. Drug Deliv. Rev., 2000, 45(1), 89-121.
    • (2000) Adv. Drug Deliv. Rev. , vol.45 , Issue.1 , pp. 89-121
    • Lawrence, M.J.1    Rees, G.D.2
  • 15
    • 0035937597 scopus 로고    scopus 로고
    • Nanoparticulate systems for the delivery of antisense oligonucleotides
    • Lambert, G.; Fattal, E.; Couvreur, P. Nanoparticulate systems for the delivery of antisense oligonucleotides. Adv. Drug Deliv. Rev., 2001, 47(1), 99-112.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , Issue.1 , pp. 99-112
    • Lambert, G.1    Fattal, E.2    Couvreur, P.3
  • 16
    • 0028837083 scopus 로고
    • Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug-delivery
    • Brannonpeppas, L. Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug-delivery. Int. J. Pharm., 1995, 116(1), 1-9.
    • (1995) Int. J. Pharm. , vol.116 , Issue.1 , pp. 1-9
    • Brannonpeppas, L.1
  • 18
    • 0037072566 scopus 로고    scopus 로고
    • Nanoparticles in cancer therapy and diagnosis
    • Brigger, I.; Dubernet, C.; Couvreur, P. Nanoparticles in cancer therapy and diagnosis. Adv. Drug Deliv. Rev., 2002, 54(5), 631-651.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , Issue.5 , pp. 631-651
    • Brigger, I.1    Dubernet, C.2    Couvreur, P.3
  • 19
    • 0141676399 scopus 로고    scopus 로고
    • Chemotherapeutic engineering: Application and further development of chemical engineering principles for chemotherapy of cancer and other diseases
    • Feng, S.S.; Chien, S. Chemotherapeutic engineering: application and further development of chemical engineering principles for chemotherapy of cancer and other diseases. Chem. Eng. Sci., 2003, 58(18), 4087-4114.
    • (2003) Chem. Eng. Sci. , vol.58 , Issue.18 , pp. 4087-4114
    • Feng, S.S.1    Chien, S.2
  • 20
    • 0842303168 scopus 로고    scopus 로고
    • Antibodies and gene therapy: Teaching old 'magic bullets' new tricks
    • Sanz, L.; Blanco, B.; Alvarez-Vallina, L. Antibodies and gene therapy: teaching old 'magic bullets' new tricks. Trends Immunol., 2004, 25(2), 85-91.
    • (2004) Trends Immunol. , vol.25 , Issue.2 , pp. 85-91
    • Sanz, L.1    Blanco, B.2    Alvarez-Vallina, L.3
  • 21
  • 22
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler, G.; Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 1975, 256(5517), 495-497.
    • (1975) Nature , vol.256 , Issue.5517 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 23
    • 2942722679 scopus 로고    scopus 로고
    • Antibodies and genetically engineered related molecules: Production and purification
    • Roque, A.C.A.; Lowe, C.R.; Taipa, M.A. Antibodies and genetically engineered related molecules: production and purification. Biotechnol. Prog., 2004, 20(3), 639-654.
    • (2004) Biotechnol. Prog. , vol.20 , Issue.3 , pp. 639-654
    • Roque, A.C.A.1    Lowe, C.R.2    Taipa, M.A.3
  • 26
    • 0033506261 scopus 로고    scopus 로고
    • Ribosome display: An in vitro method for selection and evolution of antibodies from libraries
    • Schaffitzel, C.; Hanes, J.; Jermutus, L.; Pluckthun, A. Ribosome display: an in vitro method for selection and evolution of antibodies from libraries. J. Immunol. Methods, 1999, 231(1-2), 119-135.
    • (1999) J. Immunol. Methods , vol.231 , Issue.1-2 , pp. 119-135
    • Schaffitzel, C.1    Hanes, J.2    Jermutus, L.3    Pluckthun, A.4
  • 27
    • 0025978976 scopus 로고
    • Man-Made antibodies
    • Winter, G.; Milstein, C., Man-Made antibodies. Nature, 1991, 349(6307), 293-299.
    • (1991) Nature , vol.349 , Issue.6307 , pp. 293-299
    • Winter, G.1    Milstein, C.2
  • 29
    • 73449137187 scopus 로고    scopus 로고
    • Antibody-conjugated nanoparticles for biomedical applications
    • 439389
    • Arruebo, M.; Valladares, M.; Gonzalez-Fernandez, A. Antibody-conjugated nanoparticles for biomedical applications. J. Nanomater., 2009, 439389, 24 pp.
    • (2009) J. Nanomater. , pp. 24
    • Arruebo, M.1    Valladares, M.2    Gonzalez-Fernandez, A.3
  • 30
    • 0023481357 scopus 로고
    • Transport od molecules across tumor vasculature
    • Jain, R.K. Transport od molecules across tumor vasculature. Cancer Metastasis Rev., 1987, 6(4), 559-593.
    • (1987) Cancer Metastasis Rev. , vol.6 , Issue.4 , pp. 559-593
    • Jain, R.K.1
  • 31
    • 0032738485 scopus 로고    scopus 로고
    • Monoclonal antibody therapy of cancer
    • Weiner, L. Monoclonal antibody therapy of cancer. Semin. Oncol., 1999, 26(5), 43-51.
    • (1999) Semin. Oncol. , vol.26 , Issue.5 , pp. 43-51
    • Weiner, L.1
  • 32
    • 0033506131 scopus 로고    scopus 로고
    • Generating improved single-chain Fv molecules for tumor targeting
    • Adams, G.; Schier, R. Generating improved single-chain Fv molecules for tumor targeting. J. Immunol. Methods, 1999, 231(1-2), 249-260.
    • (1999) J. Immunol. Methods , vol.231 , Issue.1-2 , pp. 249-260
    • Adams, G.1    Schier, R.2
  • 33
    • 0033506366 scopus 로고    scopus 로고
    • High avidity scFv multimers; Diabodies and triabodies
    • Hudson, P.; Kortt, A. High avidity scFv multimers; diabodies and triabodies. J. Immunol. Methods, 1999, 231(1-2), 177-189.
    • (1999) J. Immunol. Methods , vol.231 , Issue.1-2 , pp. 177-189
    • Hudson, P.1    Kortt, A.2
  • 34
    • 0345195967 scopus 로고    scopus 로고
    • Factors influencing the dimer to monomer transition of an antibody single-chain Fv fragment
    • Arndt, K.; Muller, K.; Pluckthun, A. Factors influencing the dimer to monomer transition of an antibody single-chain Fv fragment. Biochemistry, 1998, 37(37), 12918-12926.
    • (1998) Biochemistry , vol.37 , Issue.37 , pp. 12918-12926
    • Arndt, K.1    Muller, K.2    Pluckthun, A.3
  • 35
    • 0030810023 scopus 로고    scopus 로고
    • Diabodies: Small bispecific antibody fragments
    • Holliger, P.; Winter, G. Diabodies: small bispecific antibody fragments. Cancer Immunol. Immunother., 1997, 45(3-4), 128-130.
    • (1997) Cancer Immunol. Immunother. , vol.45 , Issue.3-4 , pp. 128-130
    • Holliger, P.1    Winter, G.2
  • 36
    • 0034830739 scopus 로고    scopus 로고
    • Dimeric and trimeric antibodies: High avidity scFvs for cancer targeting
    • Kortt, A.; Dolezal, O.; Power, B.; Hudson, P. Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting. Biomol. Eng., 2001, 18(3), 95-108.
    • (2001) Biomol. Eng. , vol.18 , Issue.3 , pp. 95-108
    • Kortt, A.1    Dolezal, O.2    Power, B.3    Hudson, P.4
  • 37
    • 0029890636 scopus 로고    scopus 로고
    • Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-C(H)3) which exhibits rapid, high-level targeting of xenografts
    • Hu, S.; Shivery, L.; Raubitschek, A.; Sherman, M.; Williams, L.; Wong, J.; Shively, J.; Wu, A. Minibody: a novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-C(H)3) which exhibits rapid, high-level targeting of xenografts. Cancer Res., 1996, 56(13), 3055-3061.
    • (1996) Cancer Res. , vol.56 , Issue.13 , pp. 3055-3061
    • Hu, S.1    Shivery, L.2    Raubitschek, A.3    Sherman, M.4    Williams, L.5    Wong, J.6    Shively, J.7    Wu, A.8
  • 39
    • 0030796292 scopus 로고    scopus 로고
    • Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires
    • Dimasi, N.; Martin, F.; Volpari, C.; Brunetti, M.; Biasiol, G.; Altamura, S.; Cortese, R.; DeFrancesco, R.; Steinkuhler, C.; Sollazzo, M. Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires. J. Virol., 1997, 71(10), 7461-7469.
    • (1997) J. Virol. , vol.71 , Issue.10 , pp. 7461-7469
    • Dimasi, N.1    Martin, F.2    Volpari, C.3    Brunetti, M.4    Biasiol, G.5    Altamura, S.6    Cortese, R.7    Defrancesco, R.8    Steinkuhler, C.9    Sollazzo, M.10
  • 42
    • 0035524114 scopus 로고    scopus 로고
    • Improving the efficacy of antibody-based cancer therapies
    • Carter, P. Improving the efficacy of antibody-based cancer therapies. Nat. Rev. Cancer, 2001, 1(2), 118-129.
    • (2001) Nat. Rev. Cancer , vol.1 , Issue.2 , pp. 118-129
    • Carter, P.1
  • 44
    • 0034638918 scopus 로고    scopus 로고
    • New approaches to antibody therapy
    • Weiner, L.M.; Adams, G.P. New approaches to antibody therapy. Oncogene, 2000, 19(53), 6144-6151.
    • (2000) Oncogene , vol.19 , Issue.53 , pp. 6144-6151
    • Weiner, L.M.1    Adams, G.P.2
  • 45
    • 31544454201 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for direct or two-step tumor immunotargeting
    • Nobs, L.; Buchegger, F.; Gurny, R.; Allemann, E. Biodegradable nanoparticles for direct or two-step tumor immunotargeting. Bioconjug. Chem., 2006, 17(1), 139-145.
    • (2006) Bioconjug. Chem. , vol.17 , Issue.1 , pp. 139-145
    • Nobs, L.1    Buchegger, F.2    Gurny, R.3    Allemann, E.4
  • 46
    • 4644296183 scopus 로고    scopus 로고
    • Poly(lactic acid) nanoparticles labeled with biologically active neutravidin (TM) for active targeting
    • Nobs, L.; Buchegger, F.; Gurny, R.; Allemann, E. Poly(lactic acid) nanoparticles labeled with biologically active neutravidin (TM) for active targeting. Eur. J. Pharm. Biopharma., 2004, 58(3), 483-490.
    • (2004) Eur. J. Pharm. Biopharma. , vol.58 , Issue.3 , pp. 483-490
    • Nobs, L.1    Buchegger, F.2    Gurny, R.3    Allemann, E.4
  • 47
    • 34548427504 scopus 로고    scopus 로고
    • Active targeting of brain tumors using nanocarriers
    • Beduneau, A.; Saulnier, P.; Benoit, J.P. Active targeting of brain tumors using nanocarriers. Biomaterials, 2007, 28(33), 4947-4967.
    • (2007) Biomaterials , vol.28 , Issue.33 , pp. 4947-4967
    • Beduneau, A.1    Saulnier, P.2    Benoit, J.P.3
  • 48
    • 34249023676 scopus 로고    scopus 로고
    • Functionalized micellar systems for cancer targeted drug delivery
    • Sutton, D.; Nasongkla, N.; Blanco, E.; Gao, J. Functionalized micellar systems for cancer targeted drug delivery. Pharm. Res., 2007, 24(6), 1029-1046.
    • (2007) Pharm. Res. , vol.24 , Issue.6 , pp. 1029-1046
    • Sutton, D.1    Nasongkla, N.2    Blanco, E.3    Gao, J.4
  • 49
    • 0017913226 scopus 로고
    • Pharmacokinetics of liposome-encapsulated anti-tumor drugs-studies with vinblastine, actinomycin-D, Cytosine-arabinoside, and dounomycin
    • Juliano, R.L.; Stamp, D. Pharmacokinetics of liposome-encapsulated anti-tumor drugs-studies with vinblastine, actinomycin-D, Cytosine-arabinoside, and dounomycin. Biochem. Pharmacol., 1978, 27(1), 21-27.
    • (1978) Biochem. Pharmacol. , vol.27 , Issue.1 , pp. 21-27
    • Juliano, R.L.1    Stamp, D.2
  • 51
    • 0030024958 scopus 로고    scopus 로고
    • Doxorubicin encapsulated in liposomes containing surface-found polyethylene glycol: Pharmacokinetics, tumor localization, and safety in patients with AIDS-related Kaposi's sarcoma
    • Northfelt, D.W.; Martin, F.J.; Working, P.; Volberding, P.A.; Russell, J.; Newman, M.; Aantea, M.A.; Kaplan, L.D. Doxorubicin encapsulated in liposomes containing surface-found polyethylene glycol: pharmacokinetics, tumor localization, and safety in patients with AIDS-related Kaposi's sarcoma. J. Clin. Pharmacol., 1996, 36(1), 55-63.
    • (1996) J. Clin. Pharmacol. , vol.36 , Issue.1 , pp. 55-63
    • Northfelt, D.W.1    Martin, F.J.2    Working, P.3    Volberding, P.A.4    Russell, J.5    Newman, M.6    Aantea, M.A.7    Kaplan, L.D.8
  • 52
    • 0035676563 scopus 로고    scopus 로고
    • Phase III data on Caelyx (R) in ovarian cancer
    • Muggia, F.; Hamilton, A. Phase III data on Caelyx (R) in ovarian cancer. Eur. J. Cancer, 2001, 37(9), S15-S18.
    • (2001) Eur. J. Cancer , vol.37 , Issue.9
    • Muggia, F.1    Hamilton, A.2
  • 53
    • 33751419875 scopus 로고    scopus 로고
    • Nanomedicine: Developing smarter therapeutic and diagnostic modalities
    • Farokhzad, O.C.; Langer, R. Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv. Drug Deliv. Rev., 2006, 58(14), 1456-1459.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , Issue.14 , pp. 1456-1459
    • Farokhzad, O.C.1    Langer, R.2
  • 54
    • 33751183754 scopus 로고    scopus 로고
    • Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems
    • Arifin, D.Y.; Lee, L.Y.; Wang, C.H. Mathematical modeling and simulation of drug release from microspheres: implications to drug delivery systems. Adv. Drug Deliv. Rev., 2006, 58(12-13), 1274-1325.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , Issue.12-13 , pp. 1274-1325
    • Arifin, D.Y.1    Lee, L.Y.2    Wang, C.H.3
  • 56
    • 4644340922 scopus 로고    scopus 로고
    • Control of encapsulation efficiency and initial burst in polymeric microparticle systems
    • Yeo, Y.; Park, K.N. Control of encapsulation efficiency and initial burst in polymeric microparticle systems. Arch. Pharm. Res., 2004, 27(1), 1-12.
    • (2004) Arch. Pharm. Res. , vol.27 , Issue.1 , pp. 1-12
    • Yeo, Y.1    Park, K.N.2
  • 57
    • 0023557345 scopus 로고
    • The preparation and evaluation of drug-containing poly(DL-lactide) microspheres formed by the solvent evaporation method
    • Bodmeier, R.; McGinity, J.W. The preparation and evaluation of drug-containing poly(DL-lactide) microspheres formed by the solvent evaporation method. Pharm. Res., 1987, 4(6), 465-471.
    • (1987) Pharm. Res. , vol.4 , Issue.6 , pp. 465-471
    • Bodmeier, R.1    McGinity, J.W.2
  • 58
    • 0028008642 scopus 로고
    • Double-walled polymer microspheres for controlled drug-releae
    • Pekarek, K. J.; Jacob, J. S.; Mathiowitz, E. Double-walled polymer microspheres for controlled drug-releae. Nature, 1994, 367(6460), 258-260.
    • (1994) Nature , vol.367 , Issue.6460 , pp. 258-260
    • Pekarek, K.J.1    Jacob, J.S.2    Mathiowitz, E.3
  • 59
    • 72649106871 scopus 로고    scopus 로고
    • accessed July 15 2011
    • Food and Drug Administration. http://www.fda.gov/default.htm (accessed July 15, 2011)
    • Food and Drug Administration
  • 60
    • 20444459212 scopus 로고    scopus 로고
    • Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: Preparation, properties and possible applications in drug delivery
    • Avgoustakis, K. Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: preparation, properties and possible applications in drug delivery. Curr. Drug Deliv., 2004, 1(4), 321-333.
    • (2004) Curr. Drug Deliv. , vol.1 , Issue.4 , pp. 321-333
    • Avgoustakis, K.1
  • 61
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Anderson, J.M.; Shive, M.S. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev., 1997, 28(1), 5-24.
    • (1997) Adv. Drug Deliv. Rev. , vol.28 , Issue.1 , pp. 5-24
    • Anderson, J.M.1    Shive, M.S.2
  • 62
    • 33746052131 scopus 로고    scopus 로고
    • Synthesis and characterization of PLGA nanoparticles
    • Astete, C.E.; Sabliov, C.M. Synthesis and characterization of PLGA nanoparticles. J. Biomater. Sci. Polym. Ed., 2006, 17(3), 247-289.
    • (2006) J. Biomater. Sci. Polym. Ed. , vol.17 , Issue.3 , pp. 247-289
    • Astete, C.E.1    Sabliov, C.M.2
  • 63
    • 67650699494 scopus 로고    scopus 로고
    • Stimuli-responsive polymers and their applications in drug delivery
    • Bawa, P.; Pillay, V.; Choonara, Y.E.; du Toit, L.C. Stimuli-responsive polymers and their applications in drug delivery. Biomed. Mater., 2009, 4(2), 15 pp.
    • (2009) Biomed. Mater. , vol.4 , Issue.2 , pp. 15
    • Bawa, P.1    Pillay, V.2    Choonara, Y.E.3    Du Toit, L.C.4
  • 64
    • 34548859519 scopus 로고    scopus 로고
    • Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly (ethylene glycol)-b-poly(L-histidine)
    • Lee, E.S.; Oh, K.T.; Kim, D.; Youn, Y.S.; Bae, Y.H. Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly (ethylene glycol)-b-poly(L-histidine). J. Control. Release, 2007, 123(1), 19-26.
    • (2007) J. Control. Release , vol.123 , Issue.1 , pp. 19-26
    • Lee, E.S.1    Oh, K.T.2    Kim, D.3    Youn, Y.S.4    Bae, Y.H.5
  • 65
    • 68249118615 scopus 로고    scopus 로고
    • Extracellularly activated nanocarriers: A new paradigm of tumor targeted drug delivery
    • Gullotti, E.; Yeo, Y. Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery. Mo. Pharm., 2009, 6(4), 1041-1051.
    • (2009) Mo. Pharm. , vol.6 , Issue.4 , pp. 1041-1051
    • Gullotti, E.1    Yeo, Y.2
  • 66
    • 42049121123 scopus 로고    scopus 로고
    • Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy
    • Min, K.H.; Park, K.; Kim, Y.S.; Bae, S.M.; Lee, S.; Jo, H.G.; Park, R.W.; Kim, I.S.; Jeong, S.Y.; Kim, K.; Kwon, I.C. Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy. J. Control. Release, 2008, 127(3), 208-218.
    • (2008) J. Control. Release , vol.127 , Issue.3 , pp. 208-218
    • Min, K.H.1    Park, K.2    Kim, Y.S.3    Bae, S.M.4    Lee, S.5    Jo, H.G.6    Park, R.W.7    Kim, I.S.8    Jeong, S.Y.9    Kim, K.10    Kwon, I.C.11
  • 68
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumour acidity and implications for treatment
    • Stubbs, M.; McSheehy, P.M.J.; Griffiths, J.R.; Bashford, C.L. Causes and consequences of tumour acidity and implications for treatment. Mol. Med. Today, 2000, 6(1), 15-19.
    • (2000) Mol. Med. Today , vol.6 , Issue.1 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.J.2    Griffiths, J.R.3    Bashford, C.L.4
  • 69
    • 19444376142 scopus 로고    scopus 로고
    • Preparation and characterization of intelligent core-shell nanoparticles based on poly(D, L-lactide)-g-poly(N-isopropyl-acrylamide-co-methacrylic acid)
    • Lo, C.L.; Lin, K.M.; Hsiue, G.H. Preparation and characterization of intelligent core-shell nanoparticles based on poly(D, L-lactide)-g-poly(N- isopropyl-acrylamide-co-methacrylic acid). J. Control. Release, 2005, 104(3), 477-488.
    • (2005) J. Control. Release , vol.104 , Issue.3 , pp. 477-488
    • Lo, C.L.1    Lin, K.M.2    Hsiue, G.H.3
  • 70
    • 0037433470 scopus 로고    scopus 로고
    • Sulfonamide based pH-sensitive polymeric micelles: Physicochemical characteristics and pH-dependent aggregation
    • Han, S.K.; Na, K.; Bae, Y.H. Sulfonamide based pH-sensitive polymeric micelles: physicochemical characteristics and pH-dependent aggregation. Colloids Surfaces A Physicochem. Eng. Aspects, 2003, 214(1-3), 49-59.
    • (2003) Colloids Surfaces A Physicochem. Eng. Aspects , vol.214 , Issue.1-3 , pp. 49-59
    • Han, S.K.1    Na, K.2    Bae, Y.H.3
  • 71
    • 0030852017 scopus 로고    scopus 로고
    • A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure
    • Hauck, M.L.; Coffin, D.O.; Dodge, R.K.; Dewhirst, M.W.; Mitchell, J.B.; Zalutsky, M.R. A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure. Int. J. Hyperthermia, 1997, 13(3), 307-316.
    • (1997) Int. J. Hyperthermia , vol.13 , Issue.3 , pp. 307-316
    • Hauck, M.L.1    Coffin, D.O.2    Dodge, R.K.3    Dewhirst, M.W.4    Mitchell, J.B.5    Zalutsky, M.R.6
  • 72
    • 0034662609 scopus 로고    scopus 로고
    • Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
    • Kong, G.; Braun, R.D.; Dewhirst, M.W. Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res., 2000, 60(16), 4440-4445.
    • (2000) Cancer Res. , vol.60 , Issue.16 , pp. 4440-4445
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 73
    • 34547561267 scopus 로고    scopus 로고
    • Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery
    • Rapoport, N. Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery. Prog. Polym. Sci., 2007, 32(8-9), 962-990.
    • (2007) Prog. Polym. Sci. , vol.32 , Issue.8-9 , pp. 962-990
    • Rapoport, N.1
  • 74
    • 4344604026 scopus 로고    scopus 로고
    • Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods
    • Galindo-Rodriguez, S.; Allemann, E.; Fessi, H.; Doelker, E. Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods. Pharm. Res., 2004, 21(8), 1428-1439.
    • (2004) Pharm. Res. , vol.21 , Issue.8 , pp. 1428-1439
    • Galindo-Rodriguez, S.1    Allemann, E.2    Fessi, H.3    Doelker, E.4
  • 75
    • 0032472391 scopus 로고    scopus 로고
    • Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method
    • Zambaux, M.F.; Bonneaux, F.; Gref, R.; Maincent, P.; Dellacherie, E.; Alonso, M.J.; Labrude, P.; Vigneron, C. Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method. J. Control. Release, 1998, 50(1-3), 31-40.
    • (1998) J. Control. Release , vol.50 , Issue.1-3 , pp. 31-40
    • Zambaux, M.F.1    Bonneaux, F.2    Gref, R.3    Maincent, P.4    Dellacherie, E.5    Alonso, M.J.6    Labrude, P.7    Vigneron, C.8
  • 76
    • 0035848417 scopus 로고    scopus 로고
    • Effects of emulsifiers on the controlled release of paclitaxel (Taxol (R)) from nanospheres of biodegradable polymers
    • Feng, S.S.; Huang, G.F. Effects of emulsifiers on the controlled release of paclitaxel (Taxol (R)) from nanospheres of biodegradable polymers. J. Control. Release, 2001, 71(1), 53-69.
    • (2001) J. Control. Release , vol.71 , Issue.1 , pp. 53-69
    • Feng, S.S.1    Huang, G.F.2
  • 77
    • 0037161315 scopus 로고    scopus 로고
    • Vitamin e TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol (R))
    • Mu, L.; Feng, S.S. Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol (R)). J. Control. Release, 2002, 80(1-3), 129-144.
    • (2002) J. Control. Release , vol.80 , Issue.1-3 , pp. 129-144
    • Mu, L.1    Feng, S.S.2
  • 78
    • 0027155794 scopus 로고
    • Preparations of biodegradable nanopheres of water-soluble and insoluble drugs with D, L-lactide glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior
    • Niwa, T.; Takeuchi, H.; Hino, T.; Kunou, N.; Kawashima, Y. Preparations of biodegradable nanopheres of water-soluble and insoluble drugs with D, L-lactide glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior. J. Control. Release, 1993, 25(1-2), 89-98.
    • (1993) J. Control. Release , vol.25 , Issue.1-2 , pp. 89-98
    • Niwa, T.1    Takeuchi, H.2    Hino, T.3    Kunou, N.4    Kawashima, Y.5
  • 79
    • 0027133051 scopus 로고
    • In-vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles produced by a salting-out procedure
    • Allemann, E.; Leroux, J.C.; Gurny, R.; Doelker, E. In-vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles produced by a salting-out procedure. Pharm. Res., 1993, 10(12), 1732-1737.
    • (1993) Pharm. Res. , vol.10 , Issue.12 , pp. 1732-1737
    • Allemann, E.1    Leroux, J.C.2    Gurny, R.3    Doelker, E.4
  • 80
    • 0025755129 scopus 로고
    • Particle formation with supercritical fluids-a review
    • Tom, J.W.; Debenedetti, P.G. Particle formation with supercritical fluids-a review. J. Aerosol Sci., 1991, 22(5), 555-584.
    • (1991) J. Aerosol Sci. , vol.22 , Issue.5 , pp. 555-584
    • Tom, J.W.1    Debenedetti, P.G.2
  • 81
    • 0027628302 scopus 로고
    • Sub-micrometer-sized biodegradable particles of poly(l-lactic acid) via the gas antisolvent spray precipitation process
    • Randolph, T.W.; Randolph, A.D.; Mebes, M.; Yeung, S. Sub-micrometer-sized biodegradable particles of poly(l-lactic acid) via the gas antisolvent spray precipitation process. Biotechnol. Prog., 1993, 9(4), 429-435
    • (1993) Biotechnol. Prog. , vol.9 , Issue.4 , pp. 429-435
    • Randolph, T.W.1    Randolph, A.D.2    Mebes, M.3    Yeung, S.4
  • 82
    • 0035025001 scopus 로고    scopus 로고
    • Particle formation using supercritical fluids: Pharmaceutical applications
    • Tan, H.S.; Borsadia, S. Particle formation using supercritical fluids: pharmaceutical applications. Expert Opin. Ther. Pat., 2001, 11(5), 861-872.
    • (2001) Expert Opin. Ther. Pat. , vol.11 , Issue.5 , pp. 861-872
    • Tan, H.S.1    Borsadia, S.2
  • 83
    • 33751529235 scopus 로고    scopus 로고
    • Supercritical antisolvent precipitation of PHBV microparticles
    • Costa, M.S.; Duarte, A.R.C.; Cardoso, M.M.; Duarte, C.M.M. Supercritical antisolvent precipitation of PHBV microparticles. Int. J. Pharm., 2007, 328(1), 72-77.
    • (2007) Int. J. Pharm. , vol.328 , Issue.1 , pp. 72-77
    • Costa, M.S.1    Duarte, A.R.C.2    Cardoso, M.M.3    Duarte, C.M.M.4
  • 85
    • 0023450012 scopus 로고
    • Effect of molecular-weight (mbarw) of n-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
    • Seymour, L.W.; Duncan, R.; Strohalm, J.; Kopecek, J. Effect of molecular-weight (mbarw) of n-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. J. Biomed. Mater. Res., 1987, 21(11), 1341-1358.
    • (1987) J. Biomed. Mater. Res. , vol.21 , Issue.11 , pp. 1341-1358
    • Seymour, L.W.1    Duncan, R.2    Strohalm, J.3    Kopecek, J.4
  • 86
    • 0025778796 scopus 로고
    • Non-phagocytic uptake of intravenously injected microspheres in rat spleen-influence of particle-size and hydrophilic coating
    • Moghimi, S.M.; Porter, C.J.H.; Muir, I.S.; Illum, L.; Davis, S.S. non-phagocytic uptake of intravenously injected microspheres in rat spleen-influence of particle-size and hydrophilic coating. Biochem. Biophys. Res. Commun., 1991, 177(2), 861-866.
    • (1991) Biochem. Biophys. Res. Commun. , vol.177 , Issue.2 , pp. 861-866
    • Moghimi, S.M.1    Porter, C.J.H.2    Muir, I.S.3    Illum, L.4    Davis, S.S.5
  • 88
    • 0032496713 scopus 로고    scopus 로고
    • Serum-mediated recognition of liposomes by phagocytic cells of the reticuloendothelial system-the concept of tissue specificity
    • Moghimi, S.M.; Patel, H.M. Serum-mediated recognition of liposomes by phagocytic cells of the reticuloendothelial system-the concept of tissue specificity. Adv. Drug Deliv. Rev., 1998, 32(1-2), 45-60.
    • (1998) Adv. Drug Deliv. Rev. , vol.32 , Issue.1-2 , pp. 45-60
    • Moghimi, S.M.1    Patel, H.M.2
  • 89
    • 0019929258 scopus 로고
    • Is half-life of curculating liposomes determined by changes in their permeability
    • Senior, J.; Gregoriadis, G. Is half-life of curculating liposomes determined by changes in their permeability. FEBS Lett., 1982, 145(1), 109-114.
    • (1982) FEBS Lett. , vol.145 , Issue.1 , pp. 109-114
    • Senior, J.1    Gregoriadis, G.2
  • 90
    • 0021848043 scopus 로고
    • Tissue distribution of liposmies exhibiting long kalf-lives in the circulation after intravenous-injection
    • Senior, J.; Crawley, J.C.W.; Gregoriadis, G. Tissue distribution of liposmies exhibiting long kalf-lives in the circulation after intravenous-injection. Biochim. Biophys. Acta, 1985, 839(1), 1-8.
    • (1985) Biochim. Biophys. Acta , vol.839 , Issue.1 , pp. 1-8
    • Senior, J.1    Crawley, J.C.W.2    Gregoriadis, G.3
  • 91
    • 0029379537 scopus 로고
    • Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system
    • Storm, G.; Belliot, S.O.; Daemen, T.; Lasic, D.D. surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system. Adv. Drug Deliv. Rev., 1995, 17(1), 31-48.
    • (1995) Adv. Drug Deliv. Rev. , vol.17 , Issue.1 , pp. 31-48
    • Storm, G.1    Belliot, S.O.2    Daemen, T.3    Lasic, D.D.4
  • 93
    • 84863685606 scopus 로고    scopus 로고
    • Birdi, K.S., Ed.; CRC Press: Denmark
    • Maitra, A. In: Handbook of Surface and Colloid; Birdi, K.S., Ed.; CRC Press: Denmark, 1997; pp. 603-611.
    • (1997) Handbook of Surface and Colloid , pp. 603-611
    • Maitra, A.1
  • 94
    • 0028222291 scopus 로고
    • Long-circulating (sterically stabilized) liposomes for targeted drug-delivery
    • Allen, T.M. Long-circulating (sterically stabilized) liposomes for targeted drug-delivery. Trends Pharmacol. Sci., 1994, 15(7), 215-220.
    • (1994) Trends Pharmacol. Sci. , vol.15 , Issue.7 , pp. 215-220
    • Allen, T.M.1
  • 95
    • 34250819325 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery
    • Va n Vlerken, L.E.; Vyas, T.K.; Amiji, M.M. Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery. Pharm. Res., 2007, 24(8), 1405-1414.
    • (2007) Pharm. Res. , vol.24 , Issue.8 , pp. 1405-1414
    • Va Vlerken, L.E.1    Vyas, T.K.2    Amiji, M.M.3
  • 96
    • 15044348714 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-modified poly(epsilon-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer
    • Shenoy, D.B.; Amiji, M.A. Poly(ethylene oxide)-modified poly(epsilon-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer. Int. J. Pharm., 2005, 293(1-2), 261-270.
    • (2005) Int. J. Pharm. , vol.293 , Issue.1-2 , pp. 261-270
    • Shenoy, D.B.1    Amiji, M.A.2
  • 97
    • 33847018888 scopus 로고    scopus 로고
    • Vivo real-time tracking of single quantum dots conjugated with monoclonal anti-HER2 antibody in tumors of mice
    • Tada, H.; Higuchi, H.; Wanatabe, T.M.; Ohuchi, N. In vivo real-time tracking of single quantum dots conjugated with monoclonal anti-HER2 antibody in tumors of mice. Cancer Res., 2007, 67(3), 1138-1144.
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 1138-1144
    • Tada, H.1    Higuchi, H.2    Wanatabe, T.M.3    Ohuchi, N.4
  • 99
    • 0037115543 scopus 로고    scopus 로고
    • Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
    • Sapra, P.; Allen, T.M. Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Res., 2002, 62(24), 7190-7194.
    • (2002) Cancer Res. , vol.62 , Issue.24 , pp. 7190-7194
    • Sapra, P.1    Allen, T.M.2
  • 100
    • 0028036158 scopus 로고
    • Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumor-cells in culture
    • Bennis, S.; Chapey, C.; Couvreur, P.; Robert, J. Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumor-cells in culture. Eur. J. Cancer, 1994, 30A(1), 89-93.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 89-93
    • Bennis, S.1    Chapey, C.2    Couvreur, P.3    Robert, J.4
  • 101
    • 0034104453 scopus 로고    scopus 로고
    • Resistance mechanisms associated with altered intracellular distribution of anticancer agents
    • Larsen, A.K.; Escargueil, A.E.; Skladanowski, A. Resistance mechanisms associated with altered intracellular distribution of anticancer agents. Pharmacol. Ther., 2000, 85(3), 217-229.
    • (2000) Pharmacol. Ther. , vol.85 , Issue.3 , pp. 217-229
    • Larsen, A.K.1    Escargueil, A.E.2    Skladanowski, A.3
  • 104
    • 0001160175 scopus 로고    scopus 로고
    • Vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
    • de Menezes, D.E.L; Pilarski, L.M.; Allen, T.M. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res., 1998, 58(15), 3320-3330.
    • (1998) Cancer Res. , vol.58 , Issue.15 , pp. 3320-3330
    • De Menezes, D.E.L.1    Pilarski, L.M.2    Allen, T.M.3
  • 105
    • 0037124466 scopus 로고    scopus 로고
    • PEGylated antibodies and antibody fragments for improved therapy: A review
    • Chapman, A.P. PEGylated antibodies and antibody fragments for improved therapy: a review. Adv. Drug Deliv. Rev., 2002, 54(4), 531-545.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , Issue.4 , pp. 531-545
    • Chapman, A.P.1
  • 106
    • 0036633640 scopus 로고    scopus 로고
    • Optical biosensors in drug discovery
    • Cooper, M.A. Optical biosensors in drug discovery. Nat. Rev. Drug Discov., 2002, 1(7), 515-528.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , Issue.7 , pp. 515-528
    • Cooper, M.A.1
  • 108
    • 0030589521 scopus 로고    scopus 로고
    • Preparation and purification of antibody-enzyme conjugates for therapeutic applications
    • Melton, R.G. Preparation and purification of antibody-enzyme conjugates for therapeutic applications. Adv. Drug Deliv. Rev., 1996, 22(3), 289-301.
    • (1996) Adv. Drug Deliv. Rev. , vol.22 , Issue.3 , pp. 289-301
    • Melton, R.G.1
  • 109
    • 0025288944 scopus 로고
    • Avidin and streptavidin
    • Green, N.M. Avidin and streptavidin. Methods Enzymol., 1990, 184, 51-67.
    • (1990) Methods Enzymol. , vol.184 , pp. 51-67
    • Green, N.M.1
  • 110
    • 0029031794 scopus 로고
    • Vector-mediated peptide drug-delivery to the brain
    • Pardridge, W.M. Vector-mediated peptide drug-delivery to the brain. Adv. Drug Deliv. Rev., 1995, 15(1-3), 109-146.
    • (1995) Adv. Drug Deliv. Rev. , vol.15 , Issue.1-3 , pp. 109-146
    • Pardridge, W.M.1
  • 111
    • 0028316572 scopus 로고
    • Immunoliposome targeting to murine cd4(+) leukocytes is dependent on immune status
    • Phillips, N.C.; Gagne, L.; Tsoukas, C.; Dahman, J. Immunoliposome targeting to murine cd4(+) leukocytes is dependent on immune status. J. Immunol., 1994, 152(6), 3168-3174.
    • (1994) J. Immunol. , vol.152 , Issue.6 , pp. 3168-3174
    • Phillips, N.C.1    Gagne, L.2    Tsoukas, C.3    Dahman, J.4
  • 112
    • 9444221978 scopus 로고    scopus 로고
    • Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells
    • Wartlick, H.; Michaelis, K.; Balthasar, S.; Strebhardt, K.; Kreuter, J.; Langer, K. Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells. J. Drug Target., 2004, 12(7), 461-471.
    • (2004) J. Drug Target. , vol.12 , Issue.7 , pp. 461-471
    • Wartlick, H.1    Michaelis, K.2    Balthasar, S.3    Strebhardt, K.4    Kreuter, J.5    Langer, K.6
  • 113
    • 20444375424 scopus 로고    scopus 로고
    • Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes
    • Dinauer, N.; Balthasar, S.; Weber, C.; Kreuter, J.; Langer, K.; Von Briesen, H. Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes. Biomaterials, 2005, 26(29), 5898-5906.
    • (2005) Biomaterials , vol.26 , Issue.29 , pp. 5898-5906
    • Dinauer, N.1    Balthasar, S.2    Weber, C.3    Kreuter, J.4    Langer, K.5    Von Briesen, H.6
  • 114
    • 0025981079 scopus 로고
    • Activity of amphipathic poly(ethylene glycol)-5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target
    • Klibanov, A.L.; Maruyama, K.; Beckerleg, A.M.; Torchilin, V.P.; Huang, L. Activity of amphipathic poly(ethylene glycol)-5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target. Biochim. Biophys. Acta, 1991, 1062(2), 142-148.
    • (1991) Biochim. Biophys. Acta , vol.1062 , Issue.2 , pp. 142-148
    • Klibanov, A.L.1    Maruyama, K.2    Beckerleg, A.M.3    Torchilin, V.P.4    Huang, L.5
  • 115
    • 0028099635 scopus 로고
    • Immunoliposomes and PEGylated immunoliposomes: Possible use for targeted delivery of imaging agents
    • Torchilin, V.P. Immunoliposomes and PEGylated immunoliposomes: possible use for targeted delivery of imaging agents. Immunomethods, 1994, 4(3), 244-58.
    • (1994) Immunomethods , vol.4 , Issue.3 , pp. 244-258
    • Torchilin, V.P.1
  • 116
    • 0029120094 scopus 로고
    • A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells
    • Allen, T.M.; Brandeis, E.; Hansen, C.B.; Kao, G.Y.; Zalipsky, S. A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells. Biochim. Biophys. Acta, 1995, 1237(2), 99-108.
    • (1995) Biochim. Biophys. Acta , vol.1237 , Issue.2 , pp. 99-108
    • Allen, T.M.1    Brandeis, E.2    Hansen, C.B.3    Kao, G.Y.4    Zalipsky, S.5
  • 117
    • 0028884966 scopus 로고
    • Attachment of antibodies to sterically stabilized liposomes-evaluation, comparison and optimization of coupling procedures
    • Hansen, C.B.; Kao, G.Y.; Moase, E.H.; Zalipsky, S.; Allen, T.M. Attachment of antibodies to sterically stabilized liposomes-evaluation, comparison and optimization of coupling procedures. Biochim. Biophys. Acta, 1995, 1239(2), 133-144.
    • (1995) Biochim. Biophys. Acta , vol.1239 , Issue.2 , pp. 133-144
    • Hansen, C.B.1    Kao, G.Y.2    Moase, E.H.3    Zalipsky, S.4    Allen, T.M.5
  • 118
    • 0028882571 scopus 로고
    • A novel strategy affords high-yield coupling of antibody fab' fragments to liposomes
    • Shahinian, S.; Silvius, J.R. A novel strategy affords high-yield coupling of antibody fab' fragments to liposomes. Biochim. Biophys. Acta, 1995, 1239(2), 157-167.
    • (1995) Biochim. Biophys. Acta , vol.1239 , Issue.2 , pp. 157-167
    • Shahinian, S.1    Silvius, J.R.2
  • 119
    • 0028953974 scopus 로고
    • Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal-antibodies
    • Maruyama, K.; Takizawa, T.; Yuda, T.; Kennel, S.J.; Huang, L.; Iwatsuru, M. Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal-antibodies. Biochim. Biophys. Acta, 1995, 1234(1), 74-80.
    • (1995) Biochim. Biophys. Acta , vol.1234 , Issue.1 , pp. 74-80
    • Maruyama, K.1    Takizawa, T.2    Yuda, T.3    Kennel, S.J.4    Huang, L.5    Iwatsuru, M.6
  • 123
    • 33746172167 scopus 로고    scopus 로고
    • Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
    • Kirpotin, D.B.; Drummond, D.C.; Shao, Y.; Shalaby, M.R.; Hong, K.L.; Nielsen, U.B.; Marks, J.D.; Benz, C.C.; Park, J.W. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res., 2006, 66(13), 6732-6740.
    • (2006) Cancer Res. , vol.66 , Issue.13 , pp. 6732-6740
    • Kirpotin, D.B.1    Drummond, D.C.2    Shao, Y.3    Shalaby, M.R.4    Hong, K.L.5    Nielsen, U.B.6    Marks, J.D.7    Benz, C.C.8    Park, J.W.9
  • 124
    • 0034671316 scopus 로고    scopus 로고
    • Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice
    • Sugano, M.; Egilmez, N.K.; Yokota, S.J.; Chen, F.A.; Harding, J.; Huang, S.K.; Bankert, R.B. Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice. Cancer Res., 2000, 60(24), 6942-6949.
    • (2000) Cancer Res. , vol.60 , Issue.24 , pp. 6942-6949
    • Sugano, M.1    Egilmez, N.K.2    Yokota, S.J.3    Chen, F.A.4    Harding, J.5    Huang, S.K.6    Bankert, R.B.7
  • 125
    • 62649125368 scopus 로고    scopus 로고
    • Tumor-specific anti-nucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice
    • ElBayoumi, T.A.; Torchilin, V.P. Tumor-specific anti-nucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice. Mol. Pharm., 2009, 6(1), 246-254.
    • (2009) Mol. Pharm. , vol.6 , Issue.1 , pp. 246-254
    • Elbayoumi, T.A.1    Torchilin, V.P.2
  • 126
    • 63549094211 scopus 로고    scopus 로고
    • Tumor-targeted nanomedicines: Enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody
    • El Bayoumil, T.; Torchilin, V.P. Tumor-targeted nanomedicines: enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody. Clin. Cancer Res., 2009, 15(6), 1973-1980.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.6 , pp. 1973-1980
    • El Bayoumil, T.1    Torchilin, V.P.2
  • 128
    • 1042290308 scopus 로고    scopus 로고
    • Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab' fragments
    • Sapra, P.; Moase, E.H.; Ma, J.; Allen, T.M., Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab' fragments. Clin. Cancer Res., 2004, 10(3), 1100-1111.
    • (2004) Clin. Cancer Res. , vol.10 , Issue.3 , pp. 1100-1111
    • Sapra, P.1    Moase, E.H.2    Ma, J.3    Allen, T.M.4
  • 129
    • 18244362593 scopus 로고    scopus 로고
    • Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates
    • Allen, T.M.; Mumbengegwi, D.R.; Charrois, G.J.R. Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates. Clin. Cancer Res., 2005, 11(9), 3567-3573.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.9 , pp. 3567-3573
    • Allen, T.M.1    Mumbengegwi, D.R.2    Charrois, G.J.R.3
  • 130
    • 1842478453 scopus 로고    scopus 로고
    • Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes
    • Sapra, P.; Allen, T.M. Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes. Clin. Cancer Res., 2004, 10(14), 4893-4893.
    • (2004) Clin. Cancer Res. , vol.10 , Issue.14 , pp. 4893-4893
    • Sapra, P.1    Allen, T.M.2
  • 131
    • 38549093524 scopus 로고    scopus 로고
    • Targeted delivery of anti-CD19 liposomal doxorubicin in B-cell lymphoma: A comparison of whole monoclonal antibody, Fab' fragments and single chain Fv
    • Cheng, W.W.K.; Allen, T.M. Targeted delivery of anti-CD19 liposomal doxorubicin in B-cell lymphoma: a comparison of whole monoclonal antibody, Fab' fragments and single chain Fv. J. Control. Release, 2008, 126(1), 50-58.
    • (2008) J. Control. Release , vol.126 , Issue.1 , pp. 50-58
    • Cheng, W.W.K.1    Allen, T.M.2
  • 132
    • 77952365921 scopus 로고    scopus 로고
    • Efficacy, biodistribution, and pharmacokinetics of CD22-targeted pegylated liposomal doxorubicin in a B-cell non-hodgkin's lymphoma xenograft mouse model
    • Tuscano, J.M.; Martin, S.M.; Ma, Y.P.; Zamboni, W.; O'Donnell, R.T. Efficacy, biodistribution, and pharmacokinetics of CD22-targeted pegylated liposomal doxorubicin in a B-cell non-hodgkin's lymphoma xenograft mouse model. Clin. Cancer Res., 2010, 16(10), 2760-2768.
    • (2010) Clin. Cancer Res. , vol.16 , Issue.10 , pp. 2760-2768
    • Tuscano, J.M.1    Martin, S.M.2    Ma, Y.P.3    Zamboni, W.4    O'Donnell, R.T.5
  • 134
    • 0242407091 scopus 로고    scopus 로고
    • Efficacy of immunoliposomes on cancer models in a cell-surface-antigen- density-dependent manner
    • Hosokawa, S.; Tagawa, T.; Niki, H.; Hirakawa, Y.; Nohga, K.; Nagaike, K. Efficacy of immunoliposomes on cancer models in a cell-surface-antigen-density- dependent manner. British J. Cancer, 2003, 89(8), 1545-1551.
    • (2003) British J. Cancer , vol.89 , Issue.8 , pp. 1545-1551
    • Hosokawa, S.1    Tagawa, T.2    Niki, H.3    Hirakawa, Y.4    Nohga, K.5    Nagaike, K.6
  • 136
    • 0037224431 scopus 로고    scopus 로고
    • Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice
    • Pastorino, F.; Brignole, C.; Marimpietri, D.; Sapra, P.; Moase, E.H.; Allen, T.M.; Ponzoni, M. Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice. Cancer Res., 2003, 63(1), 86-92.
    • (2003) Cancer Res. , vol.63 , Issue.1 , pp. 86-92
    • Pastorino, F.1    Brignole, C.2    Marimpietri, D.3    Sapra, P.4    Moase, E.H.5    Allen, T.M.6    Ponzoni, M.7
  • 137
    • 34248577328 scopus 로고    scopus 로고
    • Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice
    • Gupta, B.; Torchilin, V.P. Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice. Cancer Immunol. Immunother., 2007, 56(8), 1215-1223.
    • (2007) Cancer Immunol. Immunother. , vol.56 , Issue.8 , pp. 1215-1223
    • Gupta, B.1    Torchilin, V.P.2
  • 138
    • 24644485229 scopus 로고    scopus 로고
    • Targeting of daunomycin using biotinylated immunoliposomes: Pharmacokinetics, tissue distribution and in vitro pharmacological effects
    • Schnyder, A.; Krahenbuhl, S.; Drewe, J.; Huwyler, J. Targeting of daunomycin using biotinylated immunoliposomes: Pharmacokinetics, tissue distribution and in vitro pharmacological effects. J. Drug Target., 2005, 13(5), 325-335.
    • (2005) J. Drug Target. , vol.13 , Issue.5 , pp. 325-335
    • Schnyder, A.1    Krahenbuhl, S.2    Drewe, J.3    Huwyler, J.4
  • 139
    • 33846434809 scopus 로고    scopus 로고
    • Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR
    • Pan, X.G.; Wu, G.; Yang, W.L.; Barth, R.F.; Tjarks, W.; Lee, R.J. Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR. Bioconjug. Chem., 2007, 18(1), 101-108.
    • (2007) Bioconjug. Chem. , vol.18 , Issue.1 , pp. 101-108
    • Pan, X.G.1    Wu, G.2    Yang, W.L.3    Barth, R.F.4    Tjarks, W.5    Lee, R.J.6
  • 140
    • 58849127706 scopus 로고    scopus 로고
    • Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His
    • Feng, B.; Tomizawa, K.; Michiue, H.; Miyatake, S.; Han, X.J.; Fujimura, A.; Seno, M.; Kirihata, M.; Matsui, H. Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His. Biomaterials, 2009, 30(9), 1746-1755.
    • (2009) Biomaterials , vol.30 , Issue.9 , pp. 1746-1755
    • Feng, B.1    Tomizawa, K.2    Michiue, H.3    Miyatake, S.4    Han, X.J.5    Fujimura, A.6    Seno, M.7    Kirihata, M.8    Matsui, H.9
  • 141
    • 0037261231 scopus 로고    scopus 로고
    • Vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium
    • Everts, M.; Koning, G.A.; Kok, R.J.; Asgeirsdottir, S.A.; Vestweber, D.; Meijer, D.K.F.; Storm, G.; Molema, G. In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium. Pharm. Res., 2003, 20(1), 64-72.
    • (2003) Pharm. Res. , vol.20 , Issue.1 , pp. 64-72
    • Everts, M.1    Koning, G.A.2    Kok, R.J.3    Asgeirsdottir, S.A.4    Vestweber, D.5    Meijer, D.K.F.6    Storm, G.7    Molema, G.8
  • 142
    • 84863671495 scopus 로고    scopus 로고
    • Induction of CXCR2 expression and its ligands in experimental anti-MPO IgG induced glomerulonephritis
    • Van der Veen, B.S.; Asgeirsdottir, S.A.; Zwiers, P.J.; Molema, G.; Heeringa, P. Induction of CXCR2 expression and its ligands in experimental anti-MPO IgG induced glomerulonephritis. Clin. Exp. Rheumatol., 2007, 25(1), S91-S91.
    • (2007) Clin. Exp. Rheumatol. , vol.25 , Issue.1
    • Van Der Veen, B.S.1    Asgeirsdottir, S.A.2    Zwiers, P.J.3    Molema, G.4    Heeringa, P.5
  • 143
  • 144
    • 0034730469 scopus 로고    scopus 로고
    • Sterically stabilized liposomes bearing anti-HLA-DR antibodies for targeting the primary cellular reservoirs of HIV-1
    • Bestman-Smith, J.; Gourde, P.; Desormeaux, A.; Tremblay, M.J.; Bergeron, M.G. Sterically stabilized liposomes bearing anti-HLA-DR antibodies for targeting the primary cellular reservoirs of HIV-1. Biochim. Biophys. Acta, 2000, 1468(1-2), 161-174.
    • (2000) Biochim. Biophys. Acta , vol.1468 , Issue.1-2 , pp. 161-174
    • Bestman-Smith, J.1    Gourde, P.2    Desormeaux, A.3    Tremblay, M.J.4    Bergeron, M.G.5
  • 145
    • 0028835871 scopus 로고
    • Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant plasmodium-berghei infections in mice
    • Owais, M.; Varshney, G.; Choudhury, A.; Chandra, S.; Gupta, C. Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant plasmodium-berghei infections in mice. Antimicrob. Agents Chemother., 1995, 39(1), 180-184.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , Issue.1 , pp. 180-184
    • Owais, M.1    Varshney, G.2    Choudhury, A.3    Chandra, S.4    Gupta, C.5
  • 146
    • 0023628457 scopus 로고
    • Functional-drug targeting to erythrocytes invivo using antibody bearing liposomes as drug vehicles
    • Agrawal, A.; Singhal, A.; Gupta, C. Functional-drug targeting to erythrocytes invivo using antibody bearing liposomes as drug vehicles. Biochem. Biophys. Res. Commun., 1987, 148(1), 357-361.
    • (1987) Biochem. Biophys. Res. Commun. , vol.148 , Issue.1 , pp. 357-361
    • Agrawal, A.1    Singhal, A.2    Gupta, C.3
  • 147
    • 0026316627 scopus 로고
    • Chloroquine delivery to erythrocytes in plasmodium berghei-infected mice using antibody-bearing liposomes as drug vehicles
    • Chandra, S.; Agrawal, A.; Gupta, C. Chloroquine delivery to erythrocytes in plasmodium berghei-infected mice using antibody-bearing liposomes as drug vehicles. J. Biosci., 1991, 16(3), 137-144.
    • (1991) J. Biosci. , vol.16 , Issue.3 , pp. 137-144
    • Chandra, S.1    Agrawal, A.2    Gupta, C.3
  • 148
    • 44649106961 scopus 로고    scopus 로고
    • Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy
    • Chen, H.; Gao, J.; Lu, Y.; Kou, G.; Zhang, H.; Fan, L.; Sun, Z.; Guo, Y.; Zhong, Y. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J. Control. Release, 2008, 128(3), 209-216.
    • (2008) J. Control. Release , vol.128 , Issue.3 , pp. 209-216
    • Chen, H.1    Gao, J.2    Lu, Y.3    Kou, G.4    Zhang, H.5    Fan, L.6    Sun, Z.7    Guo, Y.8    Zhong, Y.9
  • 149
    • 33646773612 scopus 로고    scopus 로고
    • Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1
    • Muro, S.; Dziubla, T.; Qiu, W.N.; Leferovich, J.; Cui, X.; Berk, E.; Muzykantov, V.R. Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1. J. Pharmacol. Exp. Ther., 2006, 317(3), 1161-1169.
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , Issue.3 , pp. 1161-1169
    • Muro, S.1    Dziubla, T.2    Qiu, W.N.3    Leferovich, J.4    Cui, X.5    Berk, E.6    Muzykantov, V.R.7
  • 150
    • 77951253330 scopus 로고    scopus 로고
    • Preparation of EGFR monoclonal antibody conjugated nanoparticles and targeting to hepatocellular carcinoma
    • Liu, P.; Li, Z.; Zhu, M.; Sun, Y.; Li, Y.; Wang, H.; Duan, Y. Preparation of EGFR monoclonal antibody conjugated nanoparticles and targeting to hepatocellular carcinoma. J. Mater. Sci. Mater. Med., 2010, 21(2), 551-556.
    • (2010) J. Mater. Sci. Mater. Med. , vol.21 , Issue.2 , pp. 551-556
    • Liu, P.1    Li, Z.2    Zhu, M.3    Sun, Y.4    Li, Y.5    Wang, H.6    Duan, Y.7
  • 151
    • 42049089314 scopus 로고    scopus 로고
    • Overcoming the formulation obstacles towards targeted chemotherapy: In vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles
    • Debotton, N.; Parnes, M.; Kadouche, J.; Benita, S. Overcoming the formulation obstacles towards targeted chemotherapy: in vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles. J. Control. Release, 2008, 127(3), 219-230.
    • (2008) J. Control. Release , vol.127 , Issue.3 , pp. 219-230
    • Debotton, N.1    Parnes, M.2    Kadouche, J.3    Benita, S.4
  • 155
    • 77956541489 scopus 로고    scopus 로고
    • Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab')(2) for hepatocellular carcinoma
    • Jin, C.; Qian, N.S.; Zhao, W.; Yang, W.Q.; Bai, L.; Wu, H.; Wang, M.C.; Song, W.J.; Dou, K.F. Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab')(2) for hepatocellular carcinoma. Biomacromolecules, 2010, 1 (9), 2422-2431.
    • (2010) Biomacromolecules , vol.1 , Issue.9 , pp. 2422-2431
    • Jin, C.1    Qian, N.S.2    Zhao, W.3    Yang, W.Q.4    Bai, L.5    Wu, H.6    Wang, M.C.7    Song, W.J.8    Dou, K.F.9
  • 156
    • 84873070852 scopus 로고    scopus 로고
    • World Health Organization accessed August 4 2011
    • World Health Organization. http://www.who.int (accessed August 4 2011)
  • 157
    • 77949762340 scopus 로고    scopus 로고
    • Targeting of drugs and nanoparticles to tumors
    • Ruoslahti, E.; Bhatia, S.N.; Sailor, M.J. Targeting of drugs and nanoparticles to tumors. J. Cell Biol., 2010, 188(6), 759-768.
    • (2010) J. Cell Biol. , vol.188 , Issue.6 , pp. 759-768
    • Ruoslahti, E.1    Bhatia, S.N.2    Sailor, M.J.3
  • 158
    • 4444379133 scopus 로고    scopus 로고
    • Nanoparticle and targeted systems for cancer therapy
    • Brannon-Peppas, L.; Blanchette, J.O. Nanoparticle and targeted systems for cancer therapy. Adv. Drug Deliv. Rev., 2004, 56(11), 1649-1659.
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , Issue.11 , pp. 1649-1659
    • Brannon-Peppas, L.1    Blanchette, J.O.2
  • 159
    • 0042887615 scopus 로고    scopus 로고
    • An overview of targeted treatments in cancer
    • Abou-Jawde, R.; Choueiri, T.; Alemany, C.; Mekhail, T. An overview of targeted treatments in cancer. Clin. Ther., 2003, 25(8), 2121-2137.
    • (2003) Clin. Ther. , vol.25 , Issue.8 , pp. 2121-2137
    • Abou-Jawde, R.1    Choueiri, T.2    Alemany, C.3    Mekhail, T.4
  • 160
    • 0036597879 scopus 로고    scopus 로고
    • Recent progress in drug delivery systems for anticancer agents
    • Kim, C.K.; Lim, S.J. Recent progress in drug delivery systems for anticancer agents. Arch. Pharm. Res., 2002, 25(3), 229-239.
    • (2002) Arch. Pharm. Res. , vol.25 , Issue.3 , pp. 229-239
    • Kim, C.K.1    Lim, S.J.2
  • 161
    • 34247475688 scopus 로고    scopus 로고
    • Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles
    • Liu, Y.Y.; Miyoshi, H.; Nakamura, M. Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles. Int. J. Cancer, 2007, 120(12), 2527-2537.
    • (2007) Int. J. Cancer , vol.120 , Issue.12 , pp. 2527-2537
    • Liu, Y.Y.1    Miyoshi, H.2    Nakamura, M.3
  • 162
    • 55849099605 scopus 로고    scopus 로고
    • Active targeting schemes for nanoparticle systems in cancer therapeutics
    • Byrne, J.D.; Betancourt, T.; Brannon-Peppas, L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv. Drug Deliv. Rev., 2008, 60(15), 1615-1626.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , Issue.15 , pp. 1615-1626
    • Byrne, J.D.1    Betancourt, T.2    Brannon-Peppas, L.3
  • 163
    • 66549120963 scopus 로고    scopus 로고
    • New generation of multifunctional nanoparticles for Cancer Imaging and Therapy
    • Park, K.; Lee, S.; Kang, E.; Kim, K.; Choi, K.; Kwon, I.C. New generation of multifunctional nanoparticles for Cancer Imaging and Therapy. Adv. Funct. Mater., 2009, 19(10), 1553-1566.
    • (2009) Adv. Funct. Mater. , vol.19 , Issue.10 , pp. 1553-1566
    • Park, K.1    Lee, S.2    Kang, E.3    Kim, K.4    Choi, K.5    Kwon, I.C.6
  • 164
    • 78649974950 scopus 로고    scopus 로고
    • Advances in the field of nanooncology
    • Jain, K.K. Advances in the field of nanooncology. BMC Med., 2010, 8, 83.
    • (2010) BMC Med. , vol.8 , pp. 83
    • Jain, K.K.1
  • 165
    • 78650910950 scopus 로고    scopus 로고
    • Drug targeting strategies in cancer treatment: An overview
    • Arias, J.L. Drug targeting strategies in cancer treatment: an overview. Mini Rev. Med. Chem., 2011, 11(1), 1-17.
    • (2011) Mini Rev. Med. Chem. , vol.11 , Issue.1 , pp. 1-17
    • Arias, J.L.1
  • 166
    • 79959303001 scopus 로고    scopus 로고
    • Drug delivery strategies in targeting cancer: Current concepts and future developments
    • Arias, J.L. Drug delivery strategies in targeting cancer: current concepts and future developments. Curr. Drug Targets, 2011, 12(8), 1094-1095.
    • (2011) Curr. Drug Targets , vol.12 , Issue.8 , pp. 1094-1095
    • Arias, J.L.1
  • 168
    • 75149175575 scopus 로고    scopus 로고
    • Colloidal nanocarriers: A review on formulation technology, types and applications toward targeted drug delivery
    • Mishra, B.; Patel, B.B.; Tiwari, S. Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery. Nanomedicine, 2010, 6(1), 9-24.
    • (2010) Nanomedicine , vol.6 , Issue.1 , pp. 9-24
    • Mishra, B.1    Patel, B.B.2    Tiwari, S.3
  • 169
    • 79952649516 scopus 로고    scopus 로고
    • Antibody-targeted nanoparticles for cancer therapy
    • Fay, F.; Scott, C.J. Antibody-targeted nanoparticles for cancer therapy. Immunotherapy, 2011, 3(3), 381-394.
    • (2011) Immunotherapy , vol.3 , Issue.3 , pp. 381-394
    • Fay, F.1    Scott, C.J.2
  • 170
    • 0036144454 scopus 로고    scopus 로고
    • Thrombospondin-1 expression in patients with pathologic stage T3 prostate cancer undergoing radical prostatectomy: Association with p53 alterations, tumor angiogenesis, and tumor progression
    • Grossfeld, G.D.; Carroll, P.R.; Lindeman, N.; Meng, M.W.; Groshen, S.; Feng, A.C.; Hawes, D.; Cote, R.J. Thrombospondin-1 expression in patients with pathologic stage T3 prostate cancer undergoing radical prostatectomy: association with p53 alterations, tumor angiogenesis, and tumor progression. Urology, 2002, 59(1), 97-102.
    • (2002) Urology , vol.59 , Issue.1 , pp. 97-102
    • Grossfeld, G.D.1    Carroll, P.R.2    Lindeman, N.3    Meng, M.W.4    Groshen, S.5    Feng, A.C.6    Hawes, D.7    Cote, R.J.8
  • 171
    • 0031927962 scopus 로고    scopus 로고
    • New developments in angiogenesis: A major mechanism for tumor growth and target for therapy
    • Jones, A.; Harris, A.L. New developments in angiogenesis: a major mechanism for tumor growth and target for therapy. Cancer J. Sci. Am., 1998, 4(4), 209-217.
    • (1998) Cancer J. Sci. Am. , vol.4 , Issue.4 , pp. 209-217
    • Jones, A.1    Harris, A.L.2
  • 172
    • 0034176467 scopus 로고    scopus 로고
    • Molecular targets and cancer therapeutics: Discovery, development and clinical validation
    • Teicher, B.A. Molecular targets and cancer therapeutics: discovery, development and clinical validation. Drug Resist. Updat., 2000, 3(2), 67-73.
    • (2000) Drug Resist. Updat. , vol.3 , Issue.2 , pp. 67-73
    • Teicher, B.A.1
  • 173
    • 84863685606 scopus 로고    scopus 로고
    • Birdi, K.S., Ed.; CRC Press: Boca Raton
    • Maitra, A. In: Handbook of Surface and Colloid; Birdi, K.S., Ed.; CRC Press: Boca Raton, 1997; pp. 603-611.
    • (1997) Handbook of Surface and Colloid , pp. 603-611
    • Maitra, A.1
  • 175
    • 0024839642 scopus 로고
    • Tumoritropic and lymphotropic principles of macromolecular drugs
    • Maeda, H.; Matsumura, Y. Tumoritropic and lymphotropic principles of macromolecular drugs. Crit. Rev. Ther. Drug Carrier Syst., 1989, 6(3), 193-210.
    • (1989) Crit. Rev. Ther. Drug Carrier Syst. , vol.6 , Issue.3 , pp. 193-210
    • Maeda, H.1    Matsumura, Y.2
  • 176
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer-chemotherapy- mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura, Y.; Maeda, H. A new concept for macromolecular therapeutics in cancer-chemotherapy-mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res., 1986, 46(12), 6387-6392.
    • (1986) Cancer Res. , vol.46 , Issue.12 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 177
    • 20544451841 scopus 로고    scopus 로고
    • Specific occlusion of murine and human tumor vasculature by VCAM-1-targeted recombinant fusion proteins
    • Dienst, A.; Grunow, A.; Unruh, M.; Rabausch, B.; Nor, J.E.; Fries, J.W.U.; Gottstein, C. Specific occlusion of murine and human tumor vasculature by VCAM-1-targeted recombinant fusion proteins. J. Natl. Cancer Inst., 2005, 97(10), 733-747.
    • (2005) J. Natl. Cancer Inst. , vol.97 , Issue.10 , pp. 733-747
    • Dienst, A.1    Grunow, A.2    Unruh, M.3    Rabausch, B.4    Nor, J.E.5    Fries, J.W.U.6    Gottstein, C.7
  • 178
    • 20544455330 scopus 로고    scopus 로고
    • Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
    • Ferrara, N.; Hillan, K.J.; Novotny, W. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. Biochem. Biophys. Res. Commun., 2005, 333(2), 328-335.
    • (2005) Biochem. Biophys. Res. Commun. , vol.333 , Issue.2 , pp. 328-335
    • Ferrara, N.1    Hillan, K.J.2    Novotny, W.3
  • 179
    • 0034650802 scopus 로고    scopus 로고
    • Regulation of angiogenesis via vascular endothelial growth factor receptors
    • Veikkola, T.; Karkkainen, M.; Claesson-Welsh, L.; Alitalo, K. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res., 2000, 60(2), 203-212.
    • (2000) Cancer Res. , vol.60 , Issue.2 , pp. 203-212
    • Veikkola, T.1    Karkkainen, M.2    Claesson-Welsh, L.3    Alitalo, K.4
  • 180
    • 0030933923 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukaemia
    • Fiedler, W.; Graeven, U.; Ergun, S.; Verago, S.; Kilic, N.; Stockschlader, M.; Hossfeld, D.K. Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukaemia. Blood, 1997, 89(6), 1870-1875.
    • (1997) Blood , vol.89 , Issue.6 , pp. 1870-1875
    • Fiedler, W.1    Graeven, U.2    Ergun, S.3    Verago, S.4    Kilic, N.5    Stockschlader, M.6    Hossfeld, D.K.7
  • 182
    • 29844446910 scopus 로고    scopus 로고
    • Using anti-VEGF McAb and magnetic nanoparticles as double-targeting vector for the radioimmunotherapy of liver cancer
    • Chen, J.; Wu, H.; Han, D.Y.; Xie, C.S. Using anti-VEGF McAb and magnetic nanoparticles as double-targeting vector for the radioimmunotherapy of liver cancer. Cancer Lett., 2006, 231(2), 169-175.
    • (2006) Cancer Lett. , vol.231 , Issue.2 , pp. 169-175
    • Chen, J.1    Wu, H.2    Han, D.Y.3    Xie, C.S.4
  • 183
    • 77950495411 scopus 로고    scopus 로고
    • Study of the anti-tumor effect of anti-vascular endothelial growth factor McAb 5-fluorouracil loaded polylactic acid nanoparticles
    • Huang, K.H.; Liu, J.H.; Wang, L.Y.; Zhu, Z.H.; Chen, Q.K.; Min, J.; Chen, R.F. Study of the anti-tumor effect of anti-vascular endothelial growth factor McAb 5-fluorouracil loaded polylactic acid nanoparticles. Zhonghua Wei Chang Wai Ke Za Zhi, 2007, 10(5), 482-485.
    • (2007) Zhonghua Wei Chang Wai Ke Za Zhi , vol.10 , Issue.5 , pp. 482-485
    • Huang, K.H.1    Liu, J.H.2    Wang, L.Y.3    Zhu, Z.H.4    Chen, Q.K.5    Min, J.6    Chen, R.F.7
  • 184
    • 0036679895 scopus 로고    scopus 로고
    • Anti-integrin as novel drug-discovery targets: Potential therapeutic and diagnostic implications
    • Mousa, S.A. Anti-integrin as novel drug-discovery targets: potential therapeutic and diagnostic implications. Curr. Opin. Chem. Biol., 2002, 6(4), 534-541.
    • (2002) Curr. Opin. Chem. Biol. , vol.6 , Issue.4 , pp. 534-541
    • Mousa, S.A.1
  • 185
    • 0842333243 scopus 로고    scopus 로고
    • Alphavbeta3 and alphavbeta5 integrin antagonists inhibit angiogenesis in vitro
    • Nisato, R.E.; Tille, J.-C.; Jonczyk, A.; Goodman, S.L.; Pepper, M.S. Alphavbeta3 and alphavbeta5 integrin antagonists inhibit angiogenesis in vitro. Angiogenesis, 2003, 6(2), 105-119.
    • (2003) Angiogenesis , vol.6 , Issue.2 , pp. 105-119
    • Nisato, R.E.1    Tille, J.-C.2    Jonczyk, A.3    Goodman, S.L.4    Pepper, M.S.5
  • 186
    • 0028972105 scopus 로고
    • Antiintegrin alpha-v-beta-3 blocks human breast-cancer growth and angiogenesis in human skin
    • Brooks, P.C.; Stromblad, S.; Klemke, R.; Visscher, D.; Sarkar, F.H.; Cheresh, D.A. Antiintegrin alpha-v-beta-3 blocks human breast-cancer growth and angiogenesis in human skin. J. Clin. Invest., 1995, 96(4), 1815-1822.
    • (1995) J. Clin. Invest. , vol.96 , Issue.4 , pp. 1815-1822
    • Brooks, P.C.1    Stromblad, S.2    Klemke, R.3    Visscher, D.4    Sarkar, F.H.5    Cheresh, D.A.6
  • 187
    • 0026631151 scopus 로고
    • Involvement of integrin alpha-v gene-expression in human-melanoma tumorigenicity
    • Feldinghabermann, B.; Mueller, B.M.; Romerdahl, C.A.; Cheresh, D.A. Involvement of integrin alpha-v gene-expression in human-melanoma tumorigenicity. J. Clin. Invest., 1992, 89(6), 2018-2022.
    • (1992) J. Clin. Invest. , vol.89 , Issue.6 , pp. 2018-2022
    • Feldinghabermann, B.1    Mueller, B.M.2    Romerdahl, C.A.3    Cheresh, D.A.4
  • 188
    • 0028670833 scopus 로고
    • Integrin alpha(v)beta(3) antagonists promote tumor-regression by inducing apoptosis of angiogenic blood-vessels
    • Brooks, P.C.; Montgomery, A.M.P.; Rosenfeld, M.; Reisfeld, R.A.; Hu, T.H.; Klier, G.; Cheresh, D.A. Integrin alpha(v)beta(3) antagonists promote tumor-regression by inducing apoptosis of angiogenic blood-vessels. Cell, 1994, 79(7), 1157-1164.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.P.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.H.5    Klier, G.6    Cheresh, D.A.7
  • 190
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell-adhesion molecule-1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn, L.; Hession, C.; Tizard, R.; Vassallo, C.; Luhowskyj, S.; Chirosso, G.; Lobb, R. Direct expression cloning of vascular cell-adhesion molecule-1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell, 1989, 59(6), 1203-1211.
    • (1989) Cell , vol.59 , Issue.6 , pp. 1203-1211
    • Osborn, L.1    Hession, C.2    Tizard, R.3    Vassallo, C.4    Luhowskyj, S.5    Chirosso, G.6    Lobb, R.7
  • 192
    • 40949093071 scopus 로고    scopus 로고
    • VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo
    • Gosk, S.; Moos, T.; Gottstein, C.; Bendas, G. VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo. Biochim. Biophys. Acta, 2008, 1778(4), 854-863.
    • (2008) Biochim. Biophys. Acta , vol.1778 , Issue.4 , pp. 854-863
    • Gosk, S.1    Moos, T.2    Gottstein, C.3    Bendas, G.4
  • 193
  • 194
    • 0347382317 scopus 로고    scopus 로고
    • Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase
    • Kondo, M.; Asai, T.; Katanasaka, Y.; Sadzuka, Y.; Tsukada, H.; Ogino, K.; Taki, T.; Baba, K.; Oku, N. Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase. Int. J. Cancer, 2004, 108(2), 301-306.
    • (2004) Int. J. Cancer , vol.108 , Issue.2 , pp. 301-306
    • Kondo, M.1    Asai, T.2    Katanasaka, Y.3    Sadzuka, Y.4    Tsukada, H.5    Ogino, K.6    Taki, T.7    Baba, K.8    Oku, N.9
  • 195
    • 20044387216 scopus 로고    scopus 로고
    • Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and etastasis
    • Sato, H.; Takino, T.; Miyamori, H. Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and etastasis. Cancer Sci., 2005, 96(4), 212-217.
    • (2005) Cancer Sci. , vol.96 , Issue.4 , pp. 212-217
    • Sato, H.1    Takino, T.2    Miyamori, H.3
  • 196
    • 0036109679 scopus 로고    scopus 로고
    • MT-MMPs play pivotal roles in cancer dissemination
    • Yana, I.; Seiki, M. MT-MMPs play pivotal roles in cancer dissemination. Clin. Exp. Metastasis, 2002, 19(3), 209-215.
    • (2002) Clin. Exp. Metastasis , vol.19 , Issue.3 , pp. 209-215
    • Yana, I.1    Seiki, M.2
  • 197
    • 1242329830 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: A promising target in solid tumours
    • Laskin, J.J.; Sandier, A.B. Epidermal growth factor receptor: a promising target in solid tumours. Cancer Treat. Rev., 2004, 30(1), 1-17.
    • (2004) Cancer Treat. Rev. , vol.30 , Issue.1 , pp. 1-17
    • Laskin, J.J.1    Sandier, A.B.2
  • 198
    • 0036323564 scopus 로고    scopus 로고
    • The development and clinical use of trastuzumab (Herceptin)
    • Harries, M.; Smith, I. The development and clinical use of trastuzumab (Herceptin). Endocr. Relat. Cancer, 2002, 9(2), 75-85.
    • (2002) Endocr. Relat. Cancer , vol.9 , Issue.2 , pp. 75-85
    • Harries, M.1    Smith, I.2
  • 199
    • 67649954736 scopus 로고    scopus 로고
    • Trastuzumab-functionalized nanoparticles of biodegradable copolymers for targeted delivery of docetaxel
    • Sun, B.; Feng, S.S. Trastuzumab-functionalized nanoparticles of biodegradable copolymers for targeted delivery of docetaxel. Nanomedicine, 2009, 4(4), 431-445.
    • (2009) Nanomedicine , vol.4 , Issue.4 , pp. 431-445
    • Sun, B.1    Feng, S.S.2
  • 200
    • 58149098874 scopus 로고    scopus 로고
    • Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanoparticles
    • Anhorn, M.G.; Wagner, S.; Kreuter, J.; Langer, K.; Von Briesen, H. Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanoparticles. Bioconjug. Chem., 2008, 19(12), 2321-2331.
    • (2008) Bioconjug. Chem. , vol.19 , Issue.12 , pp. 2321-2331
    • Anhorn, M.G.1    Wagner, S.2    Kreuter, J.3    Langer, K.4    Von Briesen, H.5
  • 201
    • 33846809309 scopus 로고    scopus 로고
    • Differential tumor cell targeting of anti-HER2 (Herceptin (R)) and anti-CD20 (Mabthera (R)) coupled nanoparticles
    • Cirstoiu-Hapca, A.; Bossy-Nobs, L.; Buchegger, F.; Gurny, R.; Delie, F. Differential tumor cell targeting of anti-HER2 (Herceptin (R)) and anti-CD20 (Mabthera (R)) coupled nanoparticles. Int. J. Pharm., 2007, 331(2), 190-196.
    • (2007) Int. J. Pharm. , vol.331 , Issue.2 , pp. 190-196
    • Cirstoiu-Hapca, A.1    Bossy-Nobs, L.2    Buchegger, F.3    Gurny, R.4    Delie, F.5
  • 202
    • 34249894977 scopus 로고    scopus 로고
    • Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody
    • Kocbek, P.; Obermajer, N.; Cegnar, M.; Kos, J.; Kristl, J. Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J. Control. Release, 2007, 120(1-2), 18-26.
    • (2007) J. Control. Release , vol.120 , Issue.1-2 , pp. 18-26
    • Kocbek, P.1    Obermajer, N.2    Cegnar, M.3    Kos, J.4    Kristl, J.5
  • 203
    • 44649106961 scopus 로고    scopus 로고
    • Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy
    • Chen, H.W.; Gao, J.; Lu, Y.; Kou, G.; Zhang, H.; Fan, L.; Sun, Z.G.; Guo, Y.J.; Zhong, Y.Q. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J. Control. Release, 2008, 128(3), 209-216.
    • (2008) J. Control. Release , vol.128 , Issue.3 , pp. 209-216
    • Chen, H.W.1    Gao, J.2    Lu, Y.3    Kou, G.4    Zhang, H.5    Fan, L.6    Sun, Z.G.7    Guo, Y.J.8    Zhong, Y.Q.9
  • 204
    • 36148987251 scopus 로고    scopus 로고
    • Multifunctional poly(D, L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer
    • Sun, B.; Ranganathan, B.; Feng, S.S. Multifunctional poly(D, L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer. Biomaterials, 2008, 29(4), 475-486.
    • (2008) Biomaterials , vol.29 , Issue.4 , pp. 475-486
    • Sun, B.1    Ranganathan, B.2    Feng, S.S.3
  • 205
    • 77957942614 scopus 로고    scopus 로고
    • A strategy for precision engineering of nanoparticles of biodegradable copolymers for quantitative control of targeted drug delivery
    • Liu, Y.T.; Li, K.; Liu, B.; Feng, S.S. A strategy for precision engineering of nanoparticles of biodegradable copolymers for quantitative control of targeted drug delivery. Biomaterials, 2010, 31(35), 9145-9155.
    • (2010) Biomaterials , vol.31 , Issue.35 , pp. 9145-9155
    • Liu, Y.T.1    Li, K.2    Liu, B.3    Feng, S.S.4
  • 206
    • 0032985063 scopus 로고    scopus 로고
    • Transferrin as a targeting ligand for liposomes and anticancer drugs
    • Singh, M. Transferrin as a targeting ligand for liposomes and anticancer drugs. Curr. Pharm. Des., 1999, 5(6), 443-451.
    • (1999) Curr. Pharm. Des. , vol.5 , Issue.6 , pp. 443-451
    • Singh, M.1
  • 209
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel, R.; Ward, E.; Brawley, O.; Jemal, A.J. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin., 2011, 61(4), 212-236.
    • (2011) CA Cancer J. Clin. , vol.61 , Issue.4 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.J.4
  • 210
    • 37049183697 scopus 로고
    • Human-breast cancer-correlation of relapse and survival with amplification of the her-2 neu oncogene
    • Slamon, D.J.; Clark, G.M.; Wong, S.G.; Levin, W.J.; Ullrich, A.; McGuire, W.L. Human-breast cancer-correlation of relapse and survival with amplification of the her-2 neu oncogene. Science, 1987, 235(4785), 177-182.
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 211
    • 84873061367 scopus 로고    scopus 로고
    • World Health Organization accessed August 4 2011
    • World Health Organization. Globocan Programme. http://www.globocan.iarc. fr (accessed August 4, 2011).
    • Globocan Programme
  • 212
    • 42649137232 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles for the treatment of lung diseases
    • Azarmi, S.; Roa, W.H.; Loebenberg, R. Targeted delivery of nanoparticles for the treatment of lung diseases. Adv. Drug Deliv. Rev., 2008, 60(8), 863-875.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , Issue.8 , pp. 863-875
    • Azarmi, S.1    Roa, W.H.2    Loebenberg, R.3
  • 214
    • 75449105002 scopus 로고    scopus 로고
    • A quantitative evaluation of the molecular binding affinity between a monoclonal antibody conjugated to a nanoparticle and an antigen by surface plasmon resonance
    • Debotton, N.; Zer, H.; Parnes, M.; Harush-Frenkel, O.; Kadouche, J.; Benita, S. A quantitative evaluation of the molecular binding affinity between a monoclonal antibody conjugated to a nanoparticle and an antigen by surface plasmon resonance. Eur. J. Pharm. Biopharm., 2010, 74(2), 148-156.
    • (2010) Eur. J. Pharm. Biopharm. , vol.74 , Issue.2 , pp. 148-156
    • Debotton, N.1    Zer, H.2    Parnes, M.3    Harush-Frenkel, O.4    Kadouche, J.5    Benita, S.6
  • 215
    • 21044455501 scopus 로고    scopus 로고
    • Targeting of antioxidant and anti-thrombotic drugs to endothelial cell adhesion molecules
    • Muro, S.; Muzykantov, V. R. Targeting of antioxidant and anti-thrombotic drugs to endothelial cell adhesion molecules. Curr. Pharm. Des., 2005, 11(18), 2383-2401.
    • (2005) Curr. Pharm. Des. , vol.11 , Issue.18 , pp. 2383-2401
    • Muro, S.1    Muzykantov, V.R.2
  • 216
    • 37649004944 scopus 로고    scopus 로고
    • Vivo imaging of Cu-64-labeled polymer nanoparticles targeted to the lung endothelium
    • Rossin, R.; Muro, S.; Welch, M.J.; Muzykantov, V.R.; Schuster, D.P. In vivo imaging of Cu-64-labeled polymer nanoparticles targeted to the lung endothelium. J. Nucl. Med., 2008, 49(1), 103-111.
    • (2008) J. Nucl. Med. , vol.49 , Issue.1 , pp. 103-111
    • Rossin, R.1    Muro, S.2    Welch, M.J.3    Muzykantov, V.R.4    Schuster, D.P.5
  • 218
    • 34247252488 scopus 로고    scopus 로고
    • Systematic review, including meta-analyses, on the management of locally advanced pancreatic cancer using radiation/combined modality therapy
    • Sultana, A.; Smith, C.T.; Cunningham, D.; Starling, N.; Tait, D.; Neoptolemos, J.P.; Ghaneh, P. Systematic review, including meta-analyses, on the management of locally advanced pancreatic cancer using radiation/combined modality therapy. B r. J. Cancer, 2007, 96(8), 1183-1190.
    • (2007) B R. J. Cancer , vol.96 , Issue.8 , pp. 1183-1190
    • Sultana, A.1    Smith, C.T.2    Cunningham, D.3    Starling, N.4    Tait, D.5    Neoptolemos, J.P.6    Ghaneh, P.7
  • 220
    • 23344447904 scopus 로고    scopus 로고
    • Bevacizumab as treatment for chemotherapy-resistant pancreatic cancer
    • Bruckner, H.W.; Hrehorovich, V.R.; Sawhney, H.S. Bevacizumab as treatment for chemotherapy-resistant pancreatic cancer. Anticancer Res., 2005, 25(5), 3637-3639.
    • (2005) Anticancer Res. , vol.25 , Issue.5 , pp. 3637-3639
    • Bruckner, H.W.1    Hrehorovich, V.R.2    Sawhney, H.S.3
  • 222
    • 34548858453 scopus 로고    scopus 로고
    • Phase i study of SS1P a recombinant anti-mesothelin immunotoxin given as a bolus IV infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
    • Hassan, R.; Bullock, S.; Premkumar, A.; Kreitman, R.J.; Kindler, H.; Willingham, M.C.; Pastan, I. Phase I study of SS1P a recombinant anti-mesothelin immunotoxin given as a bolus IV infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin. Cancer Res., 2007, 13(17), 5144-5149.
    • (2007) Clin. Cancer Res. , vol.13 , Issue.17 , pp. 5144-5149
    • Hassan, R.1    Bullock, S.2    Premkumar, A.3    Kreitman, R.J.4    Kindler, H.5    Willingham, M.C.6    Pastan, I.7
  • 223
    • 0015583914 scopus 로고
    • Carcinoembryonic antigen (cea) in diagnosis of pancreatic cancer
    • Ona, F.V.; Zamcheck, N.; Dhar, P.; Moore, T.; Kupchik, H.Z. Carcinoembryonic antigen (cea) in diagnosis of pancreatic cancer. Cancer, 1973, 31(2), 324-327.
    • (1973) Cancer , vol.31 , Issue.2 , pp. 324-327
    • Ona, F.V.1    Zamcheck, N.2    Dhar, P.3    Moore, T.4    Kupchik, H.Z.5
  • 224
    • 77953264383 scopus 로고    scopus 로고
    • Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells
    • Hu, C.M.J.; Kaushal, S.; Cao, H.S.T.; Aryal, S.; Sartor, M.; Esener, S.; Bouvet, M.; Zhang, L.F. Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells. Mol. Pharm., 2010, 7(3), 914-920.
    • (2010) Mol. Pharm. , vol.7 , Issue.3 , pp. 914-920
    • Hu, C.M.J.1    Kaushal, S.2    Cao, H.S.T.3    Aryal, S.4    Sartor, M.5    Esener, S.6    Bouvet, M.7    Zhang, L.F.8
  • 225
    • 0142010620 scopus 로고    scopus 로고
    • Starlike vs. classic macromolecular prodrugs: Two different antibody-targeted HPMA copolymers of doxorubicin studied in vitro and in vivo as potential anticancer drugs
    • Jelinkova, M.; Strohalm, J.; Etrych, T.; Ulbrich, K.; Rihova, B. Starlike vs. classic macromolecular prodrugs: two different antibody-targeted HPMA copolymers of doxorubicin studied in vitro and in vivo as potential anticancer drugs. Pharm. Res., 2003, 20(10), 1558-1564.
    • (2003) Pharm. Res. , vol.20 , Issue.10 , pp. 1558-1564
    • Jelinkova, M.1    Strohalm, J.2    Etrych, T.3    Ulbrich, K.4    Rihova, B.5
  • 227
    • 0037280306 scopus 로고    scopus 로고
    • The role of VEGF in normal and neoplastic hematopoiesis
    • Gerber, H.P.; Ferrara, N. The role of VEGF in normal and neoplastic hematopoiesis. J. Mol. Med. (Berl), 2003, 81(1), 20-31.
    • (2003) J. Mol. Med. (Berl) , vol.81 , Issue.1 , pp. 20-31
    • Gerber, H.P.1    Ferrara, N.2
  • 228
    • 0021222051 scopus 로고
    • A monoclonal-antibody reactive with normal and leukemic human myeloid progenitor cells
    • Griffin, J.D.; Linch, D.; Sabbath, K.; Larcom, P.; Schlossman, S.F. A monoclonal-antibody reactive with normal and leukemic human myeloid progenitor cells. Leuk. Res., 1984, 8(4), 521-534.
    • (1984) Leuk. Res. , vol.8 , Issue.4 , pp. 521-534
    • Griffin, J.D.1    Linch, D.2    Sabbath, K.3    Larcom, P.4    Schlossman, S.F.5
  • 229
    • 77956876614 scopus 로고    scopus 로고
    • Anti-CD8 conjugated nanoparticles to target mammalian cells expressing CD8
    • Bicho, A.; Peca, I.; Roque, A.; Cardoso, M.M. Anti-CD8 conjugated nanoparticles to target mammalian cells expressing CD8. Int. J. Pharm., 2010, 399(1-2), 80-86.
    • (2010) Int. J. Pharm. , vol.399 , Issue.1-2 , pp. 80-86
    • Bicho, A.1    Peca, I.2    Roque, A.3    Cardoso, M.M.4
  • 230
    • 0036865884 scopus 로고    scopus 로고
    • Innovations in design and delivery of chemotherapy for brain tumors
    • Gururangan, S.; Friedman, H.S. Innovations in design and delivery of chemotherapy for brain tumors. Neuroimaging Clin. N. Am., 2002, 12(4), 583-597.
    • (2002) Neuroimaging Clin. N. Am. , vol.12 , Issue.4 , pp. 583-597
    • Gururangan, S.1    Friedman, H.S.2
  • 231
    • 0031898769 scopus 로고    scopus 로고
    • Blood-brain barrier carrier-mediated transport and brain metabolism of amino acids
    • Pardridge, W.M. Blood-brain barrier carrier-mediated transport and brain metabolism of amino acids. Neurochem. Res., 1998, 23(5), 635-644.
    • (1998) Neurochem. Res. , vol.23 , Issue.5 , pp. 635-644
    • Pardridge, W.M.1
  • 232
    • 73449115641 scopus 로고    scopus 로고
    • The blood-brain and the blood-cerebrospinal fluid barriers: Function and dysfunction
    • Engelhardt, B.; Sorokin, L. The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Semin. Immunopathol., 2009, 31(4), 497-511.
    • (2009) Semin. Immunopathol. , vol.31 , Issue.4 , pp. 497-511
    • Engelhardt, B.1    Sorokin, L.2
  • 233
    • 0020647631 scopus 로고
    • Bicarbonate transport across the frog choroid-plexus and its control by cyclic-nucleotides
    • MAR
    • Saito, Y.; Wright, E.M. Bicarbonate transport across the frog choroid-plexus and its control by cyclic-nucleotides. J. Physiol., 1983, 336(MAR), 635-648.
    • (1983) J. Physiol. , vol.336 , pp. 635-648
    • Saito, Y.1    Wright, E.M.2
  • 234
    • 0030869483 scopus 로고    scopus 로고
    • Drug delivery to the brain
    • Pardridge, W.M. Drug delivery to the brain. J. Cereb. Blood Flow Metab., 1997, 17(7), 713-731.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , Issue.7 , pp. 713-731
    • Pardridge, W.M.1
  • 235
    • 0041837255 scopus 로고    scopus 로고
    • Blood-brain barrier efflux transport
    • Golden, P.L.; Pollack, G.M. Blood-brain barrier efflux transport. J. Pharm. Sci., 2003, 92(9), 1739-1753.
    • (2003) J. Pharm. Sci. , vol.92 , Issue.9 , pp. 1739-1753
    • Golden, P.L.1    Pollack, G.M.2
  • 236
    • 33845784758 scopus 로고    scopus 로고
    • Blood-brain barrier delivery
    • Pardridge, W.M. Blood-brain barrier delivery. Drug Discov. Today, 2007, 12(1-2), 54-61.
    • (2007) Drug Discov. Today , vol.12 , Issue.1-2 , pp. 54-61
    • Pardridge, W.M.1
  • 237
    • 0036828928 scopus 로고    scopus 로고
    • Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats
    • DiMeco, F.; Li, K.W.; Tyler, B.M.; Wolf, A.S.; Brem, H.; Olivi, A. Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats. J. Neurosurg., 2002, 97(5), 1173-1178.
    • (2002) J. Neurosurg. , vol.97 , Issue.5 , pp. 1173-1178
    • Dimeco, F.1    Li, K.W.2    Tyler, B.M.3    Wolf, A.S.4    Brem, H.5    Olivi, A.6
  • 238
    • 27944471754 scopus 로고    scopus 로고
    • Local delivery of doxorubicin for the treatment of malignant brain tumors in rats
    • Lesniak, M.S.; Upadhyay, U.; Goodwin, R.; Tyler, B.; Brem, H. Local delivery of doxorubicin for the treatment of malignant brain tumors in rats. Anticancer Res., 2005, 25(6B), 3825-3831.
    • (2005) Anticancer Res. , vol.25 , Issue.6 B , pp. 3825-3831
    • Lesniak, M.S.1    Upadhyay, U.2    Goodwin, R.3    Tyler, B.4    Brem, H.5
  • 239
    • 0037384037 scopus 로고    scopus 로고
    • A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
    • Westphal, M.; Hilt, D.C.; Bortey, E.; Delavault, P.; Olivares, R.; Warnke, P.C.; Whittle, I.R.; Jaaskelainen, J.; Ram, Z. A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro Oncol., 2003, 5(2), 79-88.
    • (2003) Neuro Oncol. , vol.5 , Issue.2 , pp. 79-88
    • Westphal, M.1    Hilt, D.C.2    Bortey, E.3    Delavault, P.4    Olivares, R.5    Warnke, P.C.6    Whittle, I.R.7    Jaaskelainen, J.8    Ram, Z.9
  • 240
    • 0033082752 scopus 로고    scopus 로고
    • Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems
    • Pardridge, W.M. Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems. Pharm. Sci. Technolo. Today, 1999, 2(2), 49-59.
    • (1999) Pharm. Sci. Technolo. Today , vol.2 , Issue.2 , pp. 49-59
    • Pardridge, W.M.1
  • 241
    • 0016430387 scopus 로고
    • Rationale for design of biologically reversible drug derivatives-prodrugs
    • Sinkula, A.A.; Yalkowsky, S.H. Rationale for design of biologically reversible drug derivatives-prodrugs. J. Pharm. Sci., 1975, 64(2), 181-210.
    • (1975) J. Pharm. Sci. , vol.64 , Issue.2 , pp. 181-210
    • Sinkula, A.A.1    Yalkowsky, S.H.2
  • 242
    • 0024501790 scopus 로고
    • Blood-brain-barrier disruption using mannitol-time course and electron-microscopy studies
    • Cosolo, W.C.; Martinello, P.; Louis, W.J.; Christophidis, N. Blood-brain-barrier disruption using mannitol-time course and electron-microscopy studies. Am. J. Physiol., 1989, 256(2), R443-R447.
    • (1989) Am. J. Physiol. , vol.256 , Issue.2
    • Cosolo, W.C.1    Martinello, P.2    Louis, W.J.3    Christophidis, N.4
  • 243
    • 0029592056 scopus 로고
    • Pharmacological blood-brain barrier modification for selective drug delivery
    • Cloughesy, T.F.; Black, K.L. Pharmacological blood-brain barrier modification for selective drug delivery. J. Neurooncol., 1995, 26(2), 125-132.
    • (1995) J. Neurooncol. , vol.26 , Issue.2 , pp. 125-132
    • Cloughesy, T.F.1    Black, K.L.2
  • 246
    • 0141764816 scopus 로고    scopus 로고
    • Drug delivery to the central nervous system: A review
    • Misra, A.; Ganesh, S.; Shahiwala, A.; Shah, S.P. Drug delivery to the central nervous system: a review. J. Pharm. Pharm. Sci., 2003, 6(2), 252-273.
    • (2003) J. Pharm. Pharm. Sci. , vol.6 , Issue.2 , pp. 252-273
    • Misra, A.1    Ganesh, S.2    Shahiwala, A.3    Shah, S.P.4
  • 247
    • 34447282032 scopus 로고    scopus 로고
    • UEA I-bearing nanoparticles for brain delivery following intranasal administration
    • Gao, X.; Chen, J.; Tao, W.; Zhu, J.; Zhang, Q.; Chen, H.; Jiang, X. UEA I-bearing nanoparticles for brain delivery following intranasal administration. Int. J. Pharm., 2007, 340(1-2), 207-215.
    • (2007) Int. J. Pharm. , vol.340 , Issue.1-2 , pp. 207-215
    • Gao, X.1    Chen, J.2    Tao, W.3    Zhu, J.4    Zhang, Q.5    Chen, H.6    Jiang, X.7
  • 248
    • 0037335187 scopus 로고    scopus 로고
    • Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • Kreuter, J.; Ramge, P.; Petrov, V.; Hamm, S.; Gelperina, S.E.; Engelhardt, B.; Alyautdin, R.; Von Briesen, H.; Begley, D.J. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm. Res., 2003, 20(3), 409-416.
    • (2003) Pharm. Res. , vol.20 , Issue.3 , pp. 409-416
    • Kreuter, J.1    Ramge, P.2    Petrov, V.3    Hamm, S.4    Gelperina, S.E.5    Engelhardt, B.6    Alyautdin, R.7    Von Briesen, H.8    Begley, D.J.9
  • 250
    • 33846499122 scopus 로고    scopus 로고
    • Chemotherapy of brain turnour using doxorubicin bound to surfactant-coated poly(butyl cyanoacrylate) nanoparticles: Revisiting the role of surfactants
    • Petri, B.; Bootz, A.; Khalansky, A.; Hekmatara, T.; Mueller, R.; Uhl, R.; Kreuter, J.; Gelperina, S. Chemotherapy of brain turnour using doxorubicin bound to surfactant-coated poly(butyl cyanoacrylate) nanoparticles: revisiting the role of surfactants. J. Control. Release, 2007, 117, 51-58.
    • (2007) J. Control. Release , vol.117 , pp. 51-58
    • Petri, B.1    Bootz, A.2    Khalansky, A.3    Hekmatara, T.4    Mueller, R.5    Uhl, R.6    Kreuter, J.7    Gelperina, S.8
  • 251
    • 0026562291 scopus 로고
    • Phagocytosis of nanoparticles by human-immunodeficiency-virus (hiv)-infected macrophages-a possibility for antiviral drug targeting
    • Schafer, V.; Vonbriesen, H.; Andreesen, R.; Steffan, A.M.; Royer, C.; Troster, S.; Kreuter, J.; Rubsamenwaigmann, H. Phagocytosis of nanoparticles by human-immunodeficiency-virus (hiv)-infected macrophages-a possibility for antiviral drug targeting. Pharm. Res., 1992, 9(4), 541-546.
    • (1992) Pharm. Res. , vol.9 , Issue.4 , pp. 541-546
    • Schafer, V.1    Vonbriesen, H.2    Andreesen, R.3    Steffan, A.M.4    Royer, C.5    Troster, S.6    Kreuter, J.7    Rubsamenwaigmann, H.8
  • 253
    • 31344441398 scopus 로고    scopus 로고
    • Molecular modeling of blood-brain barrier nutrient transporters: In silico basis for evaluation of potential drug delivery to the central nervous system
    • Allen, D.D.; Geldenhuys, W.J. Molecular modeling of blood-brain barrier nutrient transporters: in silico basis for evaluation of potential drug delivery to the central nervous system. Life Sci., 2006, 78(10), 1029-1033.
    • (2006) Life Sci. , vol.78 , Issue.10 , pp. 1029-1033
    • Allen, D.D.1    Geldenhuys, W.J.2
  • 254
    • 10444231111 scopus 로고    scopus 로고
    • Transport mechanism for aluminum citrate at the blood-brain barrier: Kinetic evidence implies involvement of system Xc(-) immortalized rat brain endothelial cells
    • Nagasawa, K.; Ito, S.; Kakuda, T.; Nagai, K.; Tamai, I.; Tsuji, A.; Fujimoto, S. Transport mechanism for aluminum citrate at the blood-brain barrier: kinetic evidence implies involvement of system Xc(-) immortalized rat brain endothelial cells. Toxicol. Lett., 2005, 155(2), 289-296.
    • (2005) Toxicol. Lett. , vol.155 , Issue.2 , pp. 289-296
    • Nagasawa, K.1    Ito, S.2    Kakuda, T.3    Nagai, K.4    Tamai, I.5    Tsuji, A.6    Fujimoto, S.7
  • 255
    • 0035292828 scopus 로고    scopus 로고
    • Delivery of peptides and proteins through the blood-brain barrier
    • Bickel, U.; Yoshikawa, T.; Pardridge, W.M. Delivery of peptides and proteins through the blood-brain barrier. Adv. Drug Deliv. Rev., 2001, 46(1-3), 247-279.
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , Issue.1-3 , pp. 247-279
    • Bickel, U.1    Yoshikawa, T.2    Pardridge, W.M.3
  • 256
    • 0021841594 scopus 로고
    • Human blood-brain-barrier insulin-receptor
    • Pardridge, W.M.; Eisenberg, J.; Yang, J. Human blood-brain-barrier insulin-receptor. J. Neurochem., 1985, 44(6), 1771-1778.
    • (1985) J. Neurochem. , vol.44 , Issue.6 , pp. 1771-1778
    • Pardridge, W.M.1    Eisenberg, J.2    Yang, J.3
  • 257
    • 0023227218 scopus 로고
    • Human blood-brain-barrier transferrin receptor
    • Pardridge, W.M.; Eisenberg, J.; Jing, Y. Human blood-brain-barrier transferrin receptor. Metabolism, 1987, 36(9), 892-895.
    • (1987) Metabolism , vol.36 , Issue.9 , pp. 892-895
    • Pardridge, W.M.1    Eisenberg, J.2    Jing, Y.3
  • 259
    • 0025223675 scopus 로고
    • Evaluation of cationized rat albumin as a potential blood-brain-barrier drug transport vector
    • Pardridge, W.M.; Triguero, D.; Buciak, J.; Yang, J. Evaluation of cationized rat albumin as a potential blood-brain-barrier drug transport vector. J. Pharmacol. Exp. Ther., 1990, 255(2), 893-899.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , Issue.2 , pp. 893-899
    • Pardridge, W.M.1    Triguero, D.2    Buciak, J.3    Yang, J.4
  • 261
    • 0026080401 scopus 로고
    • Transferrin receptor on glioblastoma-multiforme
    • Hall, W.A. Transferrin receptor on glioblastoma-multiforme. J. Neurosurg., 1991, 74(2), 313-314.
    • (1991) J. Neurosurg. , vol.74 , Issue.2 , pp. 313-314
    • Hall, W.A.1
  • 262
    • 0036518450 scopus 로고    scopus 로고
    • Receptor-mediated delivery of an antisense gene to human brain cancer cells
    • Zhang, Y.; Lee, H.J.; Boado, R.J.; Pardridge, W.M. Receptor-mediated delivery of an antisense gene to human brain cancer cells. J. Gene Med., 2002, 4(2), 183-194.
    • (2002) J. Gene Med. , vol.4 , Issue.2 , pp. 183-194
    • Zhang, Y.1    Lee, H.J.2    Boado, R.J.3    Pardridge, W.M.4
  • 264
    • 0025836586 scopus 로고
    • Selective transport of an antitransferrin receptor antibody through the blood-brain-barrier invivo
    • Pardridge, W.M.; Buciak, J.L.; Friden, P.M. Selective transport of an antitransferrin receptor antibody through the blood-brain-barrier invivo. J. Pharmacol. Exp. Ther., 1991, 259(1), 66-70.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , Issue.1 , pp. 66-70
    • Pardridge, W.M.1    Buciak, J.L.2    Friden, P.M.3
  • 265
    • 0030987679 scopus 로고    scopus 로고
    • Receptor mediated delivery of daunomycin using immunoliposomes: Pharmacokinetics and tissue distribution in the rat
    • Huwyler, J.; Yang, J.; Pardridge, W.M. Receptor mediated delivery of daunomycin using immunoliposomes: pharmacokinetics and tissue distribution in the rat. J. Pharmacol. Exp. Ther., 1997, 282(3), 1541-1546.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , Issue.3 , pp. 1541-1546
    • Huwyler, J.1    Yang, J.2    Pardridge, W.M.3
  • 266
    • 1642494593 scopus 로고    scopus 로고
    • Targeting of skeletal muscle in vitro using biotinylated immunoliposomes
    • Schnyder, A.; Krahenbuhl, S.; Torok, M.; Drewe, J.; Huwyler, J. Targeting of skeletal muscle in vitro using biotinylated immunoliposomes. Biochem. J., 2004, 377(1), 61-67.
    • (2004) Biochem. J. , vol.377 , Issue.1 , pp. 61-67
    • Schnyder, A.1    Krahenbuhl, S.2    Torok, M.3    Drewe, J.4    Huwyler, J.5
  • 267
    • 0029964091 scopus 로고    scopus 로고
    • Patterns of epidermal growth factor receptor amplification in malignant gliomas
    • Sauter, G.; Maeda, T.; Waldman, F.M.; Davis, R.L.; Feuerstein, B.G. Patterns of epidermal growth factor receptor amplification in malignant gliomas. Am. J. Pathol., 1996, 148(4), 1047-1053.
    • (1996) Am. J. Pathol. , vol.148 , Issue.4 , pp. 1047-1053
    • Sauter, G.1    Maeda, T.2    Waldman, F.M.3    Davis, R.L.4    Feuerstein, B.G.5
  • 269
    • 59649102668 scopus 로고    scopus 로고
    • Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB)
    • Ulbrich, K.; Hekmatara, T.; Herbert, E.; Kreuter, J. Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB). Eur. J. Pharm. Biopharm., 2009, 71(2), 251-256.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , Issue.2 , pp. 251-256
    • Ulbrich, K.1    Hekmatara, T.2    Herbert, E.3    Kreuter, J.4
  • 271
    • 77951921261 scopus 로고    scopus 로고
    • Targeted drug-delivery approaches by nanoparticulate carriers in the therapy of inflammatory diseases
    • Ulbrich, W.; Lamprecht, A. Targeted drug-delivery approaches by nanoparticulate carriers in the therapy of inflammatory diseases. J. R. Soc. Interface, 2010, 7(1), S55-S66.
    • (2010) J. R. Soc. Interface , vol.7 , Issue.1
    • Ulbrich, W.1    Lamprecht, A.2
  • 274
    • 0030929491 scopus 로고    scopus 로고
    • Optimization of technetium-99m-labeled PEG liposomes to image focal infection: Effects of particle size and circulation time
    • Boerman, O.C.; Oyen, W.J.G.; vanBloois, L.; Koenders, E.B.; vanderMeer, J.W.M.; Corstens, F.H.M.; Storm, G. Optimization of technetium-99m-labeled PEG liposomes to image focal infection: effects of particle size and circulation time. J. Nucl. Med., 1997, 38(3), 489-493.
    • (1997) J. Nucl. Med. , vol.38 , Issue.3 , pp. 489-493
    • Boerman, O.C.1    Oyen, W.J.G.2    Vanbloois, L.3    Koenders, E.B.4    Vandermeer, J.W.M.5    Corstens, F.H.M.6    Storm, G.7
  • 275
    • 0032407784 scopus 로고    scopus 로고
    • Technetium-99m-labeled liposomes to image experimental colitis in rabbits: Comparison with technetium-99m-HMPAO-granulocytes and technetium-99m-HYNIC-IgG
    • Dams, E.T.M.; Oyen, W.J.G.; Boerman, O.C.; Storm, G.; Laverman, P.; Koenders, E.B.; van der Meer, J.W.M.; Corstens, F.H.M. Technetium-99m-labeled liposomes to image experimental colitis in rabbits: Comparison with technetium-99m-HMPAO-granulocytes and technetium-99m-HYNIC-IgG. J. Nucl. Med., 1998, 39(12), 2172-2178.
    • (1998) J. Nucl. Med. , vol.39 , Issue.12 , pp. 2172-2178
    • Dams, E.T.M.1    Oyen, W.J.G.2    Boerman, O.C.3    Storm, G.4    Laverman, P.5    Koenders, E.B.6    Van Der Meer, J.W.M.7    Corstens, F.H.M.8
  • 278
    • 57749193734 scopus 로고    scopus 로고
    • Targeted delivery of therapeutics to endothelium
    • Simone, E.; Ding, B.-S.; Muzykantov, V. Targeted delivery of therapeutics to endothelium. Cell Tissue Res., 2009, 335(1), 283-300.
    • (2009) Cell Tissue Res. , vol.335 , Issue.1 , pp. 283-300
    • Simone, E.1    Ding, B.-S.2    Muzykantov, V.3
  • 279
    • 0025165359 scopus 로고
    • The role of endothelial-cells in inflammation
    • Pober, J.S.; Cotran, R.S.The role of endothelial-cells in inflammation. Transplantation, 1990, 50(4), 537-544.
    • (1990) Transplantation , vol.50 , Issue.4 , pp. 537-544
    • Pober, J.S.1    Cotran, R.S.2
  • 280
    • 23644437163 scopus 로고    scopus 로고
    • Therapeutic potential of nanoparticulate systems for macrophage targeting
    • Chellat, F.; Merhi, Y.; Moreau, A.; Yahia, L. Therapeutic potential of nanoparticulate systems for macrophage targeting. Biomaterials, 2005, 26(35), 7260-7275.
    • (2005) Biomaterials , vol.26 , Issue.35 , pp. 7260-7275
    • Chellat, F.1    Merhi, Y.2    Moreau, A.3    Yahia, L.4
  • 281
    • 0028792386 scopus 로고
    • Mediation of inflammation by encephalitogenic cells-interferon-gamma induction of nitric-oxide synthase and cyclooxygenase-2
    • Misko, T.P.; Trotter, J.L.; Cross, A.H. Mediation of inflammation by encephalitogenic cells-interferon-gamma induction of nitric-oxide synthase and cyclooxygenase-2. J. Neuroimmunol., 1995, 61(2), 195-204.
    • (1995) J. Neuroimmunol. , vol.61 , Issue.2 , pp. 195-204
    • Misko, T.P.1    Trotter, J.L.2    Cross, A.H.3
  • 282
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste, E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. (Berl), 1997, 75(3), 165-173.
    • (1997) J. Mol. Med. (Berl) , vol.75 , Issue.3 , pp. 165-173
    • Benveniste, E.N.1
  • 283
    • 0025736324 scopus 로고
    • Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues
    • Koch, A.E.; Burrows, J.C.; Haines, G.K.; Carlos, T.M.; Harlan, J.M.; Leibovich, S.J. Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab. Invest., 1991, 64(3), 313-320.
    • (1991) Lab. Invest. , vol.64 , Issue.3 , pp. 313-320
    • Koch, A.E.1    Burrows, J.C.2    Haines, G.K.3    Carlos, T.M.4    Harlan, J.M.5    Leibovich, S.J.6
  • 286
    • 0025020024 scopus 로고
    • Intercellular-adhesion molecule-1 (icam-1) in the pathogenesis of asthma
    • Wegner, C.D.; Gundel, R.H.; Reilly, P.; Haynes, N.; Letts, L.G.; Rothlein, R. Intercellular-adhesion molecule-1 (icam-1) in the pathogenesis of asthma. Science, 1990, 247(4941), 456-459.
    • (1990) Science , vol.247 , Issue.4941 , pp. 456-459
    • Wegner, C.D.1    Gundel, R.H.2    Reilly, P.3    Haynes, N.4    Letts, L.G.5    Rothlein, R.6
  • 288
    • 0025994758 scopus 로고
    • Endothelial leukocyte adhesion molecule-1 mediates antigen-induced acute airway inflammation and late-phase airway-obstruction in monkeys
    • Gundel, R.H.; Wegner, C.D.; Torcellini, C.A.; Clarke, C.C.; Haynes, N.; Rothlein, R.; Smith, C.W.; Letts, L.G. Endothelial leukocyte adhesion molecule-1 mediates antigen-induced acute airway inflammation and late-phase airway-obstruction in monkeys. J. Clin. Invest., 1991, 88(4), 1407-1411.
    • (1991) J. Clin. Invest. , vol.88 , Issue.4 , pp. 1407-1411
    • Gundel, R.H.1    Wegner, C.D.2    Torcellini, C.A.3    Clarke, C.C.4    Haynes, N.5    Rothlein, R.6    Smith, C.W.7    Letts, L.G.8
  • 289
    • 0026667154 scopus 로고
    • The role of intercellular-adhesion molecule-1 in chronic airway inflammation
    • Gundel, R. H.; Wegner, C.D.; Torcellini, C.A.; Letts, L.G. The role of intercellular-adhesion molecule-1 in chronic airway inflammation. Clin. Exp. Allergy, 1992, 22(5), 569-575.
    • (1992) Clin. Exp. Allergy , vol.22 , Issue.5 , pp. 569-575
    • Gundel, R.H.1    Wegner, C.D.2    Torcellini, C.A.3    Letts, L.G.4
  • 290
    • 0027477314 scopus 로고
    • A monoclonal-antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation invivo
    • Weg, V.B.; Williams, T.J.; Lobb, R.R.; Nourshargh, S. A monoclonal-antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation invivo. J. Exp. Med., 1993, 177(2), 561-566.
    • (1993) J. Exp. Med. , vol.177 , Issue.2 , pp. 561-566
    • Weg, V.B.1    Williams, T.J.2    Lobb, R.R.3    Nourshargh, S.4
  • 293
    • 0034799909 scopus 로고    scopus 로고
    • Suppression of chronic streptococcal cell wall-induced arthritis in Lewis rats by liposomal clodronate
    • Richards, P.J.; Williams, B.D.; Williams, A.S. Suppression of chronic streptococcal cell wall-induced arthritis in Lewis rats by liposomal clodronate. Rheumatology, 2001, 40(9), 978-987.
    • (2001) Rheumatology , vol.40 , Issue.9 , pp. 978-987
    • Richards, P.J.1    Williams, B.D.2    Williams, A.S.3
  • 294
    • 65649115761 scopus 로고    scopus 로고
    • Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate
    • Ishihara, T.; Kubota, T.; Choi, T.; Higaki, M. Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate. J. Pharmacol. Exp. Ther., 2009, 329(2), 412-417.
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , Issue.2 , pp. 412-417
    • Ishihara, T.1    Kubota, T.2    Choi, T.3    Higaki, M.4
  • 295
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in lewis rats after elimination of macrophages
    • Huitinga, I.; Vanrooijen, N.; Degroot, C.J.A.; Uitdehaag, B.M.J.; Dijkstra, C.D. Suppression of experimental allergic encephalomyelitis in lewis rats after elimination of macrophages. J. Exp. Med., 1990, 172(4), 1025-1033.
    • (1990) J. Exp. Med. , vol.172 , Issue.4 , pp. 1025-1033
    • Huitinga, I.1    Vanrooijen, N.2    Degroot, C.J.A.3    Uitdehaag, B.M.J.4    Dijkstra, C.D.5
  • 296
    • 0029451821 scopus 로고
    • The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis
    • Bauer, J.; Huitinga, I.; Zhao, W.G.; Lassmann, H.; Hickey, W.F.; Dijkstra, C.D. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia, 1995, 15(4), 437-446.
    • (1995) Glia , vol.15 , Issue.4 , pp. 437-446
    • Bauer, J.1    Huitinga, I.2    Zhao, W.G.3    Lassmann, H.4    Hickey, W.F.5    Dijkstra, C.D.6
  • 297
    • 0036460265 scopus 로고    scopus 로고
    • Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat
    • Calvo, P.; Gouritin, B.; Villarroya, H.; Eclancher, F.; Giannavola, C.; Klein, C.; Andreux, J.P.; Couvreur, P. Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat. Eur. J. Neurosci., 2002, 15(8), 1317-1326.
    • (2002) Eur. J. Neurosci. , vol.15 , Issue.8 , pp. 1317-1326
    • Calvo, P.1    Gouritin, B.2    Villarroya, H.3    Eclancher, F.4    Giannavola, C.5    Klein, C.6    Andreux, J.P.7    Couvreur, P.8
  • 299
    • 43449095693 scopus 로고    scopus 로고
    • Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: Long-term protective effects and enhanced efficacy of methylprednisolone formulations
    • Linker, R.A.; Weller, C.; Luehder, F.; Mohr, A.; Schmidt, J.; Knauth, M.; Metselaar, J.M.; Gold, R. Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: long-term protective effects and enhanced efficacy of methylprednisolone formulations. Exp. Neurol., 2008, 211(2), 397-406.
    • (2008) Exp. Neurol. , vol.211 , Issue.2 , pp. 397-406
    • Linker, R.A.1    Weller, C.2    Luehder, F.3    Mohr, A.4    Schmidt, J.5    Knauth, M.6    Metselaar, J.M.7    Gold, R.8
  • 300
    • 0043268760 scopus 로고    scopus 로고
    • Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis
    • Schmidt, J.; Metselaar, J.M.; Wauben, M.H.M.; Toyka, K.V.; Storm, G.; Gold, R. Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain, 2003, 126(8), 1895-1904.
    • (2003) Brain , vol.126 , Issue.8 , pp. 1895-1904
    • Schmidt, J.1    Metselaar, J.M.2    Wauben, M.H.M.3    Toyka, K.V.4    Storm, G.5    Gold, R.6
  • 301
    • 11244353770 scopus 로고    scopus 로고
    • ICAM-1 recycling in endothelial cells: A novel pathway for sustained intracellular delivery and prolonged effects of drugs
    • Muro, S.; Gajewski, C.; Koval, M.; Muzykantov, V.R. ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood, 2005, 105(2), 650-658.
    • (2005) Blood , vol.105 , Issue.2 , pp. 650-658
    • Muro, S.1    Gajewski, C.2    Koval, M.3    Muzykantov, V.R.4
  • 305
    • 0029974417 scopus 로고    scopus 로고
    • Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro
    • Bender, A.R.; vonBriesen, H.; Kreuter, J.; Duncan, I.B.; RubsamenWaigmann, H. Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro. Antimicrob. Agents Chemother., 1996, 40(6), 1467-1471.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , Issue.6 , pp. 1467-1471
    • Bender, A.R.1    Vonbriesen, H.2    Kreuter, J.3    Duncan, I.B.4    Rubsamenwaigmann, H.5
  • 306
    • 0031048050 scopus 로고    scopus 로고
    • Studies on lymphoid tissue from HIV-infected individuals: Implications for the design of therapeutic strategies
    • Cohen, O.J.; Pantaleo, G.; Lam, G.K.; Fauci, A.S. Studies on lymphoid tissue from HIV-infected individuals: implications for the design of therapeutic strategies. Springer Semin. Immunopathol., 1997, 18(3), 305-322.
    • (1997) Springer Semin. Immunopathol. , vol.18 , Issue.3 , pp. 305-322
    • Cohen, O.J.1    Pantaleo, G.2    Lam, G.K.3    Fauci, A.S.4
  • 307
    • 0027049212 scopus 로고
    • Cellular proteins bound to immunodeficiency viruses-implications for pathogenesis and vaccines
    • Arthur, L.O.; Bess, J.W.; Sowder, R.C.; Benveniste, R.E.; Mann, D.L.; Chermann, J.C.; Henderson, L.E. Cellular proteins bound to immunodeficiency viruses-implications for pathogenesis and vaccines. Science, 1992, 258(5090), 1935-1938.
    • (1992) Science , vol.258 , Issue.5090 , pp. 1935-1938
    • Arthur, L.O.1    Bess, J.W.2    Sowder, R.C.3    Benveniste, R.E.4    Mann, D.L.5    Chermann, J.C.6    Henderson, L.E.7
  • 308
  • 309
    • 76849088745 scopus 로고    scopus 로고
    • Nanotechnology applied to the treatment of malaria
    • Santos-Magalhaes, N.S.; Mosqueira, V.C.F. Nanotechnology applied to the treatment of malaria. Adv. Drug Deliv. Rev., 2010, 62(4-5), 560-575.
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , Issue.4-5 , pp. 560-575
    • Santos-Magalhaes, N.S.1    Mosqueira, V.C.F.2
  • 310
    • 0022480556 scopus 로고
    • Antibody-mediated targeting of liposomes to red-cells in vivo
    • Singhal, A.; Gupta, C. Antibody-mediated targeting of liposomes to red-cells in vivo. FEBS Lett., 1986, 201(2), 321-326.
    • (1986) FEBS Lett. , vol.201 , Issue.2 , pp. 321-326
    • Singhal, A.1    Gupta, C.2
  • 311
    • 0343446135 scopus 로고    scopus 로고
    • Tuftsin-bearing liposomes in treatment of macrophage-based infections
    • Agrawal, A.; Gupta, C. Tuftsin-bearing liposomes in treatment of macrophage-based infections. Adv. Drug Deliv. Rev., 2000, 41(2), 135-146.
    • (2000) Adv. Drug Deliv. Rev. , vol.41 , Issue.2 , pp. 135-146
    • Agrawal, A.1    Gupta, C.2


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