-
1
-
-
0018717411
-
Periodate or glutaraldehyde for preparing peroxidase conjugates?
-
[1] Boorsma, D.M. and Streefkerk, J.G. (1979) Periodate or glutaraldehyde for preparing peroxidase conjugates? J. Immunol. Methods 30, 245-255.
-
(1979)
J. Immunol. Methods
, vol.30
, pp. 245-255
-
-
Boorsma, D.M.1
Streefkerk, J.G.2
-
2
-
-
0020004911
-
The preparation and cytotoxic properties of antibody-toxin conjugates
-
[2] Thorpe, P.E. and Ross, W.C.J. (1982) The preparation and cytotoxic properties of antibody-toxin conjugates. Immunol. Rev. 62, 119-158.
-
(1982)
Immunol. Rev.
, vol.62
, pp. 119-158
-
-
Thorpe, P.E.1
Ross, W.C.J.2
-
3
-
-
0025373221
-
Cytotoxicity of glucose oxidase conjugated with antibodies to target cells: Killing efficiency depends on the conjugate internalization
-
[3] Muzykantov, V.R., Trubetskaya, O.V., Puchnina, E.A., Sakharov, D.V. and Domogatsky, S.P. (1990) Cytotoxicity of glucose oxidase conjugated with antibodies to target cells: killing efficiency depends on the conjugate internalization. Biochim. Biophys. Acta 1053, 27-31.
-
(1990)
Biochim. Biophys. Acta
, vol.1053
, pp. 27-31
-
-
Muzykantov, V.R.1
Trubetskaya, O.V.2
Puchnina, E.A.3
Sakharov, D.V.4
Domogatsky, S.P.5
-
4
-
-
0023969411
-
Specific killing of human endothelial cells by antibody-conjugated glucose oxidase
-
[4] Muzykantov, M.R., Sakharov, D.V., Sinitsyn, V.V., Domogatsky, S.P., Goncharov, N.V. and Danilov, S.M. (1988) Specific killing of human endothelial cells by antibody-conjugated glucose oxidase. Anal. Biochem. 169, 383-389.
-
(1988)
Anal. Biochem.
, vol.169
, pp. 383-389
-
-
Muzykantov, M.R.1
Sakharov, D.V.2
Sinitsyn, V.V.3
Domogatsky, S.P.4
Goncharov, N.V.5
Danilov, S.M.6
-
5
-
-
0024474054
-
Immunotoxins containing glucose oxidase and lactoperoxidase with tumoricidal properties: In vitro killing effectiveness in a mouse plasmacytoma cell model
-
[5] Stanislawski, M., Rousseau, V., Goavec, M. and Ito, H. (1989) Immunotoxins containing glucose oxidase and lactoperoxidase with tumoricidal properties: in vitro killing effectiveness in a mouse plasmacytoma cell model. Cancer Res. 49, 5497-5504.
-
(1989)
Cancer Res.
, vol.49
, pp. 5497-5504
-
-
Stanislawski, M.1
Rousseau, V.2
Goavec, M.3
Ito, H.4
-
6
-
-
0015860417
-
Selective cytotoxicity of hapten-substituted cells with an antibody-enzyme conjugate
-
[6] Philpott, G.W., Shearer, W.T., Bower, R.J. and Parker, C.W. (1973) Selective cytotoxicity of hapten-substituted cells with an antibody-enzyme conjugate. J. Immunol. 111, 921-929.
-
(1973)
J. Immunol.
, vol.111
, pp. 921-929
-
-
Philpott, G.W.1
Shearer, W.T.2
Bower, R.J.3
Parker, C.W.4
-
7
-
-
0025850304
-
The Fab/c fragment of IgG produced by cleavage at cyanocysteine residues
-
[7] Wines, B.D. and Easterbrooksmith, S.B. (1991) The Fab/c fragment of IgG produced by cleavage at cyanocysteine residues. Mol. Immunol. 28, 855-863.
-
(1991)
Mol. Immunol.
, vol.28
, pp. 855-863
-
-
Wines, B.D.1
Easterbrooksmith, S.B.2
-
8
-
-
0027157591
-
Genetic construction, expression, and characterization of a single chain anti-carcinoma antibody fused to beta-lactamase
-
193
-
[8] Goshorn, S.C., Svensson, H.P., Kerr, D.E., Somerville, J.E., Senter, P.D. and Fell, H.P. (193) Genetic construction, expression, and characterization of a single chain anti-carcinoma antibody fused to beta-lactamase. Cancer Res. 53, 2123-2127.
-
Cancer Res.
, vol.53
, pp. 2123-2127
-
-
Goshorn, S.C.1
Svensson, H.P.2
Kerr, D.E.3
Somerville, J.E.4
Senter, P.D.5
Fell, H.P.6
-
9
-
-
0026569992
-
Molecular and functional characterisation of a fusion protein suited for tumour specific prodrug activation
-
[9] Bosslet, K., Czech, J., Lorenz, P., Sedlacek, H.H., Schuermann, M. and Seemann, G. (1992) Molecular and functional characterisation of a fusion protein suited for tumour specific prodrug activation. Br. J. Cancer 65, 234-238.
-
(1992)
Br. J. Cancer
, vol.65
, pp. 234-238
-
-
Bosslet, K.1
Czech, J.2
Lorenz, P.3
Sedlacek, H.H.4
Schuermann, M.5
Seemann, G.6
-
10
-
-
0025802738
-
Preparation of the Fv fragment from a short-chain mouse IgG2a anti-dansyl monoclonal antibody and use of selectively deuterated Fv analogues for two-dimensional H-1 NMR analyses of the antigen-antibody interactions
-
[10] Takahashi, H., Igarishi, T., Shimada, I. and Arata, Y. (1991) Preparation of the Fv fragment from a short-chain mouse IgG2a anti-dansyl monoclonal antibody and use of selectively deuterated Fv analogues for two-dimensional H-1 NMR analyses of the antigen-antibody interactions. Biochemistry 30, 2840-2847.
-
(1991)
Biochemistry
, vol.30
, pp. 2840-2847
-
-
Takahashi, H.1
Igarishi, T.2
Shimada, I.3
Arata, Y.4
-
12
-
-
0024407430
-
Comparison of methods for the generation of immunoreactive fragments of a monoclonal antibody (B72.3) reactive with human carcinomas
-
[12] Milenic, D.E., Esteban, J.M. and Colcher, D. (1989) Comparison of methods for the generation of immunoreactive fragments of a monoclonal antibody (B72.3) reactive with human carcinomas. J. Immunol. Methods 120, 71-83.
-
(1989)
J. Immunol. Methods
, vol.120
, pp. 71-83
-
-
Milenic, D.E.1
Esteban, J.M.2
Colcher, D.3
-
13
-
-
0023918656
-
2 fragments from monoclonal mouse IgG1 suitable for use in radioimaging
-
2 fragments from monoclonal mouse IgG1 suitable for use in radioimaging. J. Immunol. Methods 110, 229-236.
-
(1988)
J. Immunol. Methods
, vol.110
, pp. 229-236
-
-
Kurkela, R.1
Vuolas, L.2
Vihko, P.3
-
14
-
-
0020326047
-
Monoclonal antibodies: Purification, fragmentation and application to structural and functional studies of class I MHC antigens
-
[14] Parham, P., Androlewicz, M.J., Brodsky, F.M., Holmes, N.J. and Ways, J.P. (1982) Monoclonal antibodies: purification, fragmentation and application to structural and functional studies of class I MHC antigens. J. Immunol. Methods 53, 133-173.
-
(1982)
J. Immunol. Methods
, vol.53
, pp. 133-173
-
-
Parham, P.1
Androlewicz, M.J.2
Brodsky, F.M.3
Holmes, N.J.4
Ways, J.P.5
-
15
-
-
0027942213
-
Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p 185
-
[15] Eccles, S.A., Court, W.J., Box, G.A., Dean, C.J., Melton, R.G. and Springer, C.J. (1994) Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p 185. Cancer Res. 54, 5171-5177.
-
(1994)
Cancer Res.
, vol.54
, pp. 5171-5177
-
-
Eccles, S.A.1
Court, W.J.2
Box, G.A.3
Dean, C.J.4
Melton, R.G.5
Springer, C.J.6
-
16
-
-
0028940351
-
Proteolytic fragmentation with high specificity of mouse immunoglobulin G - Mapping of proteolytic cleavage sites in the hinge region
-
[16] Yamaguchi, Y., Kim, H., Kato, K., Masuda, K., Shimada, I. and Arata, Y. (1995) Proteolytic fragmentation with high specificity of mouse immunoglobulin G - Mapping of proteolytic cleavage sites in the hinge region. J. Immunol. Methods 181, 259-267.
-
(1995)
J. Immunol. Methods
, vol.181
, pp. 259-267
-
-
Yamaguchi, Y.1
Kim, H.2
Kato, K.3
Masuda, K.4
Shimada, I.5
Arata, Y.6
-
17
-
-
0023100497
-
Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody
-
[17] Blakey, D.C., Watson, G.J., Knowles, P.P. and Thorpe, P.E. (1987) Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody. Cancer Res. 47, 947-952.
-
(1987)
Cancer Res.
, vol.47
, pp. 947-952
-
-
Blakey, D.C.1
Watson, G.J.2
Knowles, P.P.3
Thorpe, P.E.4
-
18
-
-
0022970025
-
Effect of linkage variation on pharmacokinetics of ricin A chain-antibody conjugates in normal rats
-
[18] Worrell, N.R., Cumber, A.J., Parnell, G.D., Mirza, A., Forrester, J.A. and Ross, W.C.J. (1986) Effect of linkage variation on pharmacokinetics of ricin A chain-antibody conjugates in normal rats. Anti-Cancer Drug Des. 1, 179-188.
-
(1986)
Anti-cancer Drug Des.
, vol.1
, pp. 179-188
-
-
Worrell, N.R.1
Cumber, A.J.2
Parnell, G.D.3
Mirza, A.4
Forrester, J.A.5
Ross, W.C.J.6
-
19
-
-
0024246527
-
A cytotoxic agent can be generated selectively at cancer sites
-
[19] Bagshawe, K.D., Springer, C.J., Searle, F., Antoniw, P., Sharma, S.K., Melton, R.G. and Sherwood, R.F. (1988) A cytotoxic agent can be generated selectively at cancer sites. Br. J. Cancer 58, 700-703.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 700-703
-
-
Bagshawe, K.D.1
Springer, C.J.2
Searle, F.3
Antoniw, P.4
Sharma, S.K.5
Melton, R.G.6
Sherwood, R.F.7
-
20
-
-
0025373638
-
Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft model
-
[20] Sharma, S.K., Bagshawe, K.D., Burke, P.J., Boden, R.W. and Rogers, G.T. (1990) Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft model. Br. J. Cancer 61, 659-662.
-
(1990)
Br. J. Cancer
, vol.61
, pp. 659-662
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Burke, P.J.3
Boden, R.W.4
Rogers, G.T.5
-
21
-
-
0027656118
-
Application of monoclonal antibodies against cytosine deaminase for the in vivo clearance of a cytosine deaminase immunoconjugate
-
[21] Kerr, D.E., Garrigues, U.S., Wallace, P.M., Hellstrom, K.E., Hellstrom, I. and Senter, P.D. (1993) Application of monoclonal antibodies against cytosine deaminase for the in vivo clearance of a cytosine deaminase immunoconjugate. Bioconjugate Chem. 4, 353-357.
-
(1993)
Bioconjugate Chem.
, vol.4
, pp. 353-357
-
-
Kerr, D.E.1
Garrigues, U.S.2
Wallace, P.M.3
Hellstrom, K.E.4
Hellstrom, I.5
Senter, P.D.6
-
22
-
-
0023554984
-
New coupling agents for the synthesis of immunotoxins containing hindered disulphides with improved stability in vivo
-
[22] Thorpe, P.E., Wallace, P.M., Knowles, P.P., Reif, M.G., Brown, A.N.F., Watson, G.J., Knyba, R.E., Wawrzynczak, E.J. and Blakey, D.C. (1987) New coupling agents for the synthesis of immunotoxins containing hindered disulphides with improved stability in vivo. Cancer Res. 47, 5924-5931.
-
(1987)
Cancer Res.
, vol.47
, pp. 5924-5931
-
-
Thorpe, P.E.1
Wallace, P.M.2
Knowles, P.P.3
Relf, M.G.4
Brown, A.N.F.5
Watson, G.J.6
Knyba, R.E.7
Wawrzynczak, E.J.8
Blakey, D.C.9
-
23
-
-
0026794283
-
Specific activation of glucuronide prodrugs by antibody-targeted enzymes for cancer therapy
-
[23] Wang, S.M., Chern, J.W., Yeh, M.Y., Ng, Y.C., Tung, E. and Roffler, S.R. (1992) Specific activation of glucuronide prodrugs by antibody-targeted enzymes for cancer therapy. Cancer Res. 52, 4484-4491.
-
(1992)
Cancer Res.
, vol.52
, pp. 4484-4491
-
-
Wang, S.M.1
Chern, J.W.2
Yeh, M.Y.3
Ng, Y.C.4
Tung, E.5
Roffler, S.R.6
-
24
-
-
0025352171
-
Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamide
-
[24] Kerr, D.E., Senter, P.D., Burnett, W.V., Hirschberg, D.L., Hellstrom, I. and Hetlstrom, K.E. (1991) Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamide. Cancer Immunol. Immunother. 31, 202-206.
-
(1991)
Cancer Immunol. Immunother.
, vol.31
, pp. 202-206
-
-
Kerr, D.E.1
Senter, P.D.2
Burnett, W.V.3
Hirschberg, D.L.4
Hellstrom, I.5
Hetlstrom, K.E.6
-
25
-
-
0025864963
-
A novel targeted delivery system utilizing a cephalosporin-oncolytic prodrug activated by an antibody beta-lactamase conjugate for the treatment of cancer
-
[25] Shepherd, T.A., Jungheim, L.N., Meyer, D.L. and Starling, J.J. (1991) A novel targeted delivery system utilizing a cephalosporin-oncolytic prodrug activated by an antibody beta-lactamase conjugate for the treatment of cancer. Bioorg. Med. Chem. Lett. 1, 21-26.
-
(1991)
Bioorg. Med. Chem. Lett.
, vol.1
, pp. 21-26
-
-
Shepherd, T.A.1
Jungheim, L.N.2
Meyer, D.L.3
Starling, J.J.4
-
26
-
-
0026487592
-
Preparation and characterization of a beta-lactamase-Fab' conjugate for the site-specific activation of oncolytic agents
-
[26] Meyer, D.L., Jungheim, L.N., Mikolajczyk, S.D., Shepherd, T.A., Starling, J.J. and Ahlem, C.N. (1992) Preparation and characterization of a beta-lactamase-Fab' conjugate for the site-specific activation of oncolytic agents. Bioconjugate Chem. 3, 42-48.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 42-48
-
-
Meyer, D.L.1
Jungheim, L.N.2
Mikolajczyk, S.D.3
Shepherd, T.A.4
Starling, J.J.5
Ahlem, C.N.6
-
27
-
-
0026577584
-
Analysis of a conjugate between anticarcinoembryonic antigen monoclonal antibody and alkaline phosphatase for specific activation of the prodrug etoposide phosphate
-
[27] Haisma, H.J., Boven, E., Vanmuijen, M., Devries, R. and Pinedo, H.M. (1992) Analysis of a conjugate between anticarcinoembryonic antigen monoclonal antibody and alkaline phosphatase for specific activation of the prodrug etoposide phosphate. Cancer Immunol. Immunother. 34, 343-348.
-
(1992)
Cancer Immunol. Immunother.
, vol.34
, pp. 343-348
-
-
Haisma, H.J.1
Boven, E.2
Vanmuijen, M.3
Devries, R.4
Pinedo, H.M.5
-
28
-
-
0026802983
-
A monoclonal antibody-beta-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer
-
[28] Haisma, H.J., Boven, E., Vanmuijen, M., Dejong, J., Vandervijgh, W.J.F. and Pinedo, H.M. (1992) A monoclonal antibody-beta-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer. Br. J. Cancer 66, 474-478.
-
(1992)
Br. J. Cancer
, vol.66
, pp. 474-478
-
-
Haisma, H.J.1
Boven, E.2
Vanmuijen, M.3
Dejong, J.4
Vandervijgh, W.J.F.5
Pinedo, H.M.6
-
29
-
-
0025937458
-
Construction and therapeutic potential of a carboxypeptidase A/monoclonal antibody conjugate
-
[29] Esswein, A., Hanseler, E., Montejano, Y., Vitols, K.S. and Huennekens, P.M. (1991) Construction and therapeutic potential of a carboxypeptidase A/monoclonal antibody conjugate. Adv. Enzyme Regul. 31, 3-12.
-
(1991)
Adv. Enzyme Regul.
, vol.31
, pp. 3-12
-
-
Esswein, A.1
Hanseler, E.2
Montejano, Y.3
Vitols, K.S.4
Huennekens, P.M.5
-
31
-
-
0022559902
-
2 and cytotoxicity of the conjugate against JAR choriocarcinoma cells in vitro
-
2 and cytotoxicity of the conjugate against JAR choriocarcinoma cells in vitro. Br. J. Cancer 53, 377-384.
-
(1986)
Br. J. Cancer
, vol.53
, pp. 377-384
-
-
Searle, F.1
Bier, C.2
Buckley, R.G.3
Newman, S.4
Pedley, R.B.5
Bagshawe, K.D.6
Melton, R.G.7
Alwan, S.M.8
Sherwood, R.F.9
-
32
-
-
0018115212
-
Protein thiolation and reversible protein-protein conjugation. N-succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent
-
[32] Carlsson, J., Drevin, H. and Axen, R. (1978) Protein thiolation and reversible protein-protein conjugation. N-succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent. Biochem. J. 173, 723-737.
-
(1978)
Biochem. J.
, vol.173
, pp. 723-737
-
-
Carlsson, J.1
Drevin, H.2
Axen, R.3
-
33
-
-
0020518718
-
A new reagent which may be used to introduce sulphydryl groups into proteins and its use in the preparation of conjugates for immunoassay
-
[33] Duncan, R.J.S., Weston, P.D. and Wrigglesworth, R. (1983) A new reagent which may be used to introduce sulphydryl groups into proteins and its use in the preparation of conjugates for immunoassay. Anal. Biochem. 132, 68-73.
-
(1983)
Anal. Biochem.
, vol.132
, pp. 68-73
-
-
Duncan, R.J.S.1
Weston, P.D.2
Wrigglesworth, R.3
-
34
-
-
0027220125
-
Site-specific prodrug activation by antibody-beta-lactamase conjugates - Regression and long-term growth inhibition of human colon carcinoma xenograft models
-
[34] Meyer, D.L., Jungheim, L.N., Law, K.L., Mikolajczyk, S.D., Shepherd, T.A., Mackensen, D.G., Briggs, S.L. and Starling, J.J. (1993) Site-specific prodrug activation by antibody-beta-lactamase conjugates - regression and long-term growth inhibition of human colon carcinoma xenograft models. Cancer Res. 53, 3956-3963.
-
(1993)
Cancer Res.
, vol.53
, pp. 3956-3963
-
-
Meyer, D.L.1
Jungheim, L.N.2
Law, K.L.3
Mikolajczyk, S.D.4
Shepherd, T.A.5
Mackensen, D.G.6
Briggs, S.L.7
Starling, J.J.8
-
35
-
-
0014428865
-
Estimation of total, protein bound and non-protein sulphydryl groups in tissue with Ellman's reagent
-
[35] Sedlak, J. and Lindsay, R.H. (1968) Estimation of total, protein bound and non-protein sulphydryl groups in tissue with Ellman's reagent. Anal. Biochem. 25, 192-205.
-
(1968)
Anal. Biochem.
, vol.25
, pp. 192-205
-
-
Sedlak, J.1
Lindsay, R.H.2
-
36
-
-
0023823192
-
Determination of the number of ∈ -amino groups available for conjugation of effector molecules to monoclonal antibodies
-
[36] Mueller, B.M., Wrasidlo, W.A. and Reisfeld, R.A. (1988) Determination of the number of ∈ -amino groups available for conjugation of effector molecules to monoclonal antibodies. Hybridoma 7, 453-456.
-
(1988)
Hybridoma
, vol.7
, pp. 453-456
-
-
Mueller, B.M.1
Wrasidlo, W.A.2
Reisfeld, R.A.3
-
37
-
-
0018180407
-
Modification of immunoglobulin G using specific reactivity of sugar moiety
-
[37] Murayama, A., Shimada, K. and Yamamoto, T. (1978) Modification of immunoglobulin G using specific reactivity of sugar moiety. Immunochemistry 15, 523-528.
-
(1978)
Immunochemistry
, vol.15
, pp. 523-528
-
-
Murayama, A.1
Shimada, K.2
Yamamoto, T.3
-
38
-
-
0029067466
-
Engineering a unique glycosylation site for site-specific conjugation of haptens to antibody fragments
-
[38] Leung, S.O., Losman, M.J., Govindan, S.V., Griffiths, G.L., Goldenberg, D.M. and Hansen, H.J. (1995) Engineering a unique glycosylation site for site-specific conjugation of haptens to antibody fragments. J. Immunol. 154, 5919-5926.
-
(1995)
J. Immunol.
, vol.154
, pp. 5919-5926
-
-
Leung, S.O.1
Losman, M.J.2
Govindan, S.V.3
Griffiths, G.L.4
Goldenberg, D.M.5
Hansen, H.J.6
-
41
-
-
0026825698
-
Site-specific modification of a fragment of a chimeric monoclonal antibody using reverse proteolysis
-
[41] Fisch, I., Kunzi, G., Rose, K. and Offord, R.E. (1992) Site-specific modification of a fragment of a chimeric monoclonal antibody using reverse proteolysis. Bioconjugate Chem. 3, 147-153.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 147-153
-
-
Fisch, I.1
Kunzi, G.2
Rose, K.3
Offord, R.E.4
-
42
-
-
0026161934
-
Preparation of well defined protein conjugates using enzyme-assisted reverse proteolysis
-
[42] Rose, K., Vilaseca, L.A., Werlen, R., Meunier, A., Fisch, I., Jones, R.L. and Offord, R.E. (1991) Preparation of well defined protein conjugates using enzyme-assisted reverse proteolysis. Bioconjugate Chem. 2, 154-159.
-
(1991)
Bioconjugate Chem.
, vol.2
, pp. 154-159
-
-
Rose, K.1
Vilaseca, L.A.2
Werlen, R.3
Meunier, A.4
Fisch, I.5
Jones, R.L.6
Offord, R.E.7
-
43
-
-
0028500838
-
Site-specific conjugation of an enzyme and an antibody fragment
-
[43] Werlen, R.C., Lankinen, M., Rose, K., Blakey, D., Shuttleworth, H., Melton, R. and Offord, R.E. (1994) Site-specific conjugation of an enzyme and an antibody fragment. Bioconjugate Chem. 5, 411-417.
-
(1994)
Bioconjugate Chem.
, vol.5
, pp. 411-417
-
-
Werlen, R.C.1
Lankinen, M.2
Rose, K.3
Blakey, D.4
Shuttleworth, H.5
Melton, R.6
Offord, R.E.7
-
44
-
-
0028535272
-
High field, site-specific coupling of N-terminally modified beta-lactamase to a proteolytically derived single-sulfhydryl murine Fab′'
-
[44] Mikolajczyk, S.D., Meyer, D.L., Starling, J.J., Law, K.L., Rose, K., Dufour, B. and Offord, R.E. (1994) High field, site-specific coupling of N-terminally modified beta-lactamase to a proteolytically derived single-sulfhydryl murine Fab′'. Bioconjugate Chem. 5, 636-646.
-
(1994)
Bioconjugate Chem.
, vol.5
, pp. 636-646
-
-
Mikolajczyk, S.D.1
Meyer, D.L.2
Starling, J.J.3
Law, K.L.4
Rose, K.5
Dufour, B.6
Offord, R.E.7
-
45
-
-
0025186181
-
Specific activation of the prodrug mitomycin phosphate by a bispecific anti-CD30/ anti-alkaline phosphatase monoclonal antibody
-
[45] Sahin, U., Hartmann, F., Senter, P., Pohl, C., Engen, A., Diehl, V. and Pfreundschuh, M. (1990) Specific activation of the prodrug mitomycin phosphate by a bispecific anti-CD30/ anti-alkaline phosphatase monoclonal antibody. Cancer Res, 50, 6944-6948.
-
(1990)
Cancer Res
, vol.50
, pp. 6944-6948
-
-
Sahin, U.1
Hartmann, F.2
Senter, P.3
Pohl, C.4
Engen, A.5
Diehl, V.6
Pfreundschuh, M.7
-
46
-
-
0028351101
-
A bifunctional murine::Human chimeric antibody with one antigen-binding arm replaced by bacterial beta-lactamase
-
[46] Desutter, K. and Fiers, W. (1994) A bifunctional murine::human chimeric antibody with one antigen-binding arm replaced by bacterial beta-lactamase. Mol. Immunol. 31, 261-267.
-
(1994)
Mol. Immunol.
, vol.31
, pp. 261-267
-
-
Desutter, K.1
Fiers, W.2
-
47
-
-
0025720558
-
Antibody directed enzyme prodrug therapy (ADEPT) - Clinical report
-
[47] Bagshawe, K.D., Sharma, S.K., Springer, C.J., Antoniw, P., Boden, J.A., Rogers, G.T., Burke, P.J., Melton, R.G. and Sherwood, R.F. (1991) Antibody directed enzyme prodrug therapy (ADEPT) - clinical report. Dis. Marker 9, 233-238.
-
(1991)
Dis. Marker
, vol.9
, pp. 233-238
-
-
Bagshawe, K.D.1
Sharma, S.K.2
Springer, C.J.3
Antoniw, P.4
Boden, J.A.5
Rogers, G.T.6
Burke, P.J.7
Melton, R.G.8
Sherwood, R.F.9
-
48
-
-
0011341888
-
Immunogenicity of antibody-enzyme conjugates in antibody directed enzyme prodrug therapy
-
[48] Sharma, S.K., Bagshawe, K.D. and Melton, R.G. (1991) Immunogenicity of antibody-enzyme conjugates in antibody directed enzyme prodrug therapy. Antibody Immunoconjugates Radiopharm. 4, 226.
-
(1991)
Antibody Immunoconjugates Radiopharm.
, vol.4
, pp. 226
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Melton, R.G.3
-
50
-
-
0026536712
-
Activation of methotrexate-alpha-alanine by carboxypeptidase-A monoclonal antibody conjugate
-
[50] Haenseler, E., Esswein, A., Vitols, K.S., Montejano, Y., Mueller, B.M., Reisfeld, R.A. and Huennekens, F.M. (1992) Activation of methotrexate-alpha-alanine by carboxypeptidase-A monoclonal antibody conjugate. Biochemistry 31, 891-897.
-
(1992)
Biochemistry
, vol.31
, pp. 891-897
-
-
Haenseler, E.1
Esswein, A.2
Vitols, K.S.3
Montejano, Y.4
Mueller, B.M.5
Reisfeld, R.A.6
Huennekens, F.M.7
-
51
-
-
0026212613
-
In vitro and in vivo activities of monoclonal antibody-alkaline phosphatase conjugates in combination with phenol mustard phosphate
-
[51] Wallace, P.M. and Senter, P.D. (1991) In vitro and in vivo activities of monoclonal antibody-alkaline phosphatase conjugates in combination with phenol mustard phosphate. Bioconjugate Chem. 2, 349-352.
-
(1991)
Bioconjugate Chem.
, vol.2
, pp. 349-352
-
-
Wallace, P.M.1
Senter, P.D.2
-
52
-
-
0026826545
-
Monoclonal antibody beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug
-
[52] Svensson, H.P., Kadow, J.F., Vrudhula, V.M., Wallace, P.M. and Senter, P.D. (1992) Monoclonal antibody beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug, Bioconjugate Chem, 3, 176-181.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 176-181
-
-
Svensson, H.P.1
Kadow, J.F.2
Vrudhula, V.M.3
Wallace, P.M.4
Senter, P.D.5
-
53
-
-
0027249218
-
Purification of antibodies using protein L-binding framework structures in the light chain variable domain
-
[53] Nilson, B.H.K., Lögdberg, L., Kastern, W., Björck, L., and Äkerström, B. (1993) Purification of antibodies using protein L-binding framework structures in the light chain variable domain. J. Immunol. Methods 164, 33-40.
-
(1993)
J. Immunol. Methods
, vol.164
, pp. 33-40
-
-
Nilson, B.H.K.1
Lögdberg, L.2
Kastern, W.3
Björck, L.4
Äkerström, B.5
-
54
-
-
0027006648
-
Designer dyes: 'Biomimetic' ligands for the purification of pharmaceutical proteins by affinity chromatography
-
[54] Lowe, C.R., Burton, S.J., Burton, N.P., Alderton, W.K., Pitts, J.M. and Thomas, J.A. (1992) Designer dyes: 'Biomimetic' ligands for the purification of pharmaceutical proteins by affinity chromatography. Tibtech 10, 442-448.
-
(1992)
Tibtech
, vol.10
, pp. 442-448
-
-
Lowe, C.R.1
Burton, S.J.2
Burton, N.P.3
Alderton, W.K.4
Pitts, J.M.5
Thomas, J.A.6
-
55
-
-
0023142029
-
Purification of immunotoxins containing ricin A-chain and abrtn A-chain using blue sepharose CL6B
-
[55] Knowles, P.P. and Thorpe, P.E. (1987) Purification of immunotoxins containing ricin A-chain and abrtn A-chain using blue sepharose CL6B. Anal. Biochem. 160, 440-443.
-
(1987)
Anal. Biochem.
, vol.160
, pp. 440-443
-
-
Knowles, P.P.1
Thorpe, P.E.2
-
56
-
-
0028959129
-
Development of a humanized disulfide-stabilized anti-beta p185(HER2) Fv-beta-lactamase fusion protein for activation of a cephalosporin doxorubicin prodrug
-
[56] Rodrigues, M.L., Presta, L.G., Kotts, C.E., Wirth, C., Mordenti, J., Osaka, G., Wong, W.L.T., Nuijens, A., Blackburn, B. and Carter, P. (1995) Development of a humanized disulfide-stabilized anti-beta p185(HER2) Fv-beta-lactamase fusion protein for activation of a cephalosporin doxorubicin prodrug. Cancer Res. 55, 63-70.
-
(1995)
Cancer Res.
, vol.55
, pp. 63-70
-
-
Rodrigues, M.L.1
Presta, L.G.2
Kotts, C.E.3
Wirth, C.4
Mordenti, J.5
Osaka, G.6
Wong, W.L.T.7
Nuijens, A.8
Blackburn, B.9
Carter, P.10
-
57
-
-
0027655158
-
Antitumor activities of a cephalosporin prodrug in combination with monoclonal antibody-beta-lactamase conjugates
-
[57] Vrudhula, V.M., Svensson, H.P., Kennedy, K.A., Senter, P.D. and Wallace, P.M. (1993) Antitumor activities of a cephalosporin prodrug in combination with monoclonal antibody-beta-lactamase conjugates. Bioconjugate Chem. 4, 334-340.
-
(1993)
Bioconjugate Chem.
, vol.4
, pp. 334-340
-
-
Vrudhula, V.M.1
Svensson, H.P.2
Kennedy, K.A.3
Senter, P.D.4
Wallace, P.M.5
-
58
-
-
0001573930
-
Monoclonal antibody leakage from gels: Effect of support, activation and eluant composition
-
[58] Bessos, H., Appleyard, C., Micklen, L.R. and Pepper, D.S. (1991) Monoclonal antibody leakage from gels: effect of support, activation and eluant composition. Prep. Chromatogr. 1, 207-220.
-
(1991)
Prep. Chromatogr.
, vol.1
, pp. 207-220
-
-
Bessos, H.1
Appleyard, C.2
Micklen, L.R.3
Pepper, D.S.4
-
59
-
-
0026695372
-
Synthetic metal-binding protein surface domains for metal ion-dependent interaction chromatography. II. Immobilisation of synthetic metal-binding peptides from metal ion transport proteins as model bioactive protein surface domains
-
[59] Hutchens, T.W. and Yip, T. (1995) Synthetic metal-binding protein surface domains for metal ion-dependent interaction chromatography. II. Immobilisation of synthetic metal-binding peptides from metal ion transport proteins as model bioactive protein surface domains. J. Chromatogr. 604, 133-141.
-
(1995)
J. Chromatogr.
, vol.604
, pp. 133-141
-
-
Hutchens, T.W.1
Yip, T.2
-
60
-
-
0023806075
-
Single-step purification of polypeptides expressed in Escherichia colt as fusions with glutathione-S-transferase
-
[60] Smith, D.B. and Johnson, K.S. (1988) Single-step purification of polypeptides expressed in Escherichia colt as fusions with glutathione-S-transferase. Gene 67, 31-40.
-
(1988)
Gene
, vol.67
, pp. 31-40
-
-
Smith, D.B.1
Johnson, K.S.2
-
61
-
-
0024215242
-
An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein
-
[61] Maina, C.V., Riggs, P.D., Grandea, A.C., III., Slatko, B.E., Moran, L.S., Tagliamonte, J.A., McReynolds, L.A. and Guan, C.D. (1988) An Esche richia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein. Gene 74, 365-373.
-
(1988)
Gene
, vol.74
, pp. 365-373
-
-
Maina, C.V.1
Riggs, P.D.2
Grandea A.C. III3
Slatko, B.E.4
Moran, L.S.5
Tagliamonte, J.A.6
McReynolds, L.A.7
Guan, C.D.8
-
62
-
-
0028836167
-
Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography
-
[62] Casey, J.L., Keep, P.A., Chester, K.A., Robson, L., Hawkins, R.E. and Begent, R.H.J. (1995) Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography. J. Immunol. Methods 179, 105-116.
-
(1995)
J. Immunol. Methods
, vol.179
, pp. 105-116
-
-
Casey, J.L.1
Keep, P.A.2
Chester, K.A.3
Robson, L.4
Hawkins, R.E.5
Begent, R.H.J.6
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