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Volumn 32, Issue 33, 2011, Pages 8645-8653

Conatumumab (AMG 655) coated nanoparticles for targeted pro-apoptotic drug delivery

Author keywords

C FLIP; Cancer; Caspase pathway; Conatumumab; DR5; Nanoparticles

Indexed keywords

C-FLIP; CANCER; CASPASES; CONATUMUMAB; DR5;

EID: 80052960859     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.065     Document Type: Article
Times cited : (63)

References (64)
  • 1
    • 36148987251 scopus 로고    scopus 로고
    • Multifunctional poly(D, L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer
    • Sun B., Ranganathan B., Feng S.S. Multifunctional poly(D, L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer. Biomaterials 2008, 29:475-486.
    • (2008) Biomaterials , vol.29 , pp. 475-486
    • Sun, B.1    Ranganathan, B.2    Feng, S.S.3
  • 2
    • 34249894977 scopus 로고    scopus 로고
    • Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody
    • Kocbek P., Obermajer N., Cegnar M., Kos J., Kristl J. Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J Control Release 2007, 120:18-26.
    • (2007) J Control Release , vol.120 , pp. 18-26
    • Kocbek, P.1    Obermajer, N.2    Cegnar, M.3    Kos, J.4    Kristl, J.5
  • 3
    • 34548136129 scopus 로고    scopus 로고
    • Immunonanoparticles - an effective tool to impair harmful proteolysis in invasive breast tumor cells
    • Obermajer N., Kocbek P., Repnik U., Kuznik A., Cegnar M., Kristl J., et al. Immunonanoparticles - an effective tool to impair harmful proteolysis in invasive breast tumor cells. FEBS J 2007, 274:4416-4427.
    • (2007) FEBS J , vol.274 , pp. 4416-4427
    • Obermajer, N.1    Kocbek, P.2    Repnik, U.3    Kuznik, A.4    Cegnar, M.5    Kristl, J.6
  • 4
    • 35348919484 scopus 로고    scopus 로고
    • Preparation and Characterization of Paclitaxel-loaded PLGA nanoparticles coated with cationic SM5-1 single-chain antibody
    • Kou G., Gao J., Wang H., Chen H., Li B., Zhang D., et al. Preparation and Characterization of Paclitaxel-loaded PLGA nanoparticles coated with cationic SM5-1 single-chain antibody. J Biochem Mol Biol 2007, 40:731-739.
    • (2007) J Biochem Mol Biol , vol.40 , pp. 731-739
    • Kou, G.1    Gao, J.2    Wang, H.3    Chen, H.4    Li, B.5    Zhang, D.6
  • 5
    • 44649106961 scopus 로고    scopus 로고
    • Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy
    • Chen H., Gao J., Lu Y., Kou G., Zhang H., Fan L., et al. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J Control Release 2008, 128:209-216.
    • (2008) J Control Release , vol.128 , pp. 209-216
    • Chen, H.1    Gao, J.2    Lu, Y.3    Kou, G.4    Zhang, H.5    Fan, L.6
  • 6
    • 77953321090 scopus 로고    scopus 로고
    • Benefit of anti-HER2-coated paclitaxel-loaded immuno-nanoparticles in the treatment of disseminated ovarian cancer: therapeutic efficacy and biodistribution in mice
    • Cirstoiu-Hapca A., Buchegger F., Lange N., Bossy L., Gurny R., Delie F. Benefit of anti-HER2-coated paclitaxel-loaded immuno-nanoparticles in the treatment of disseminated ovarian cancer: therapeutic efficacy and biodistribution in mice. J Control Release 2010, 144:324-331.
    • (2010) J Control Release , vol.144 , pp. 324-331
    • Cirstoiu-Hapca, A.1    Buchegger, F.2    Lange, N.3    Bossy, L.4    Gurny, R.5    Delie, F.6
  • 7
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • Gao X., Cui Y., Levenson R.M., Chung L.W., Nie S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 2004, 22:969-976.
    • (2004) Nat Biotechnol , vol.22 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.4    Nie, S.5
  • 8
    • 33847190399 scopus 로고    scopus 로고
    • Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab
    • Wu G., Yang W., Barth R.F., Kawabata S., Swindall M., Bandyopadhyaya A.K., et al. Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab. Clin Cancer Res 2007, 13:1260-1268.
    • (2007) Clin Cancer Res , vol.13 , pp. 1260-1268
    • Wu, G.1    Yang, W.2    Barth, R.F.3    Kawabata, S.4    Swindall, M.5    Bandyopadhyaya, A.K.6
  • 10
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • Fesik S.W. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 2005, 5:876-885.
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 11
    • 58149456883 scopus 로고    scopus 로고
    • Death receptors as targets for anti-cancer therapy
    • Papenfuss K., Cordier S.M., Walczak H. Death receptors as targets for anti-cancer therapy. J Cell Mol Med 2008, 12:2566-2585.
    • (2008) J Cell Mol Med , vol.12 , pp. 2566-2585
    • Papenfuss, K.1    Cordier, S.M.2    Walczak, H.3
  • 12
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan F.K., Chun H.J., Zheng L., Siegel R.M., Bui K.L., Lenardo M.J. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 2000, 288:2351-2354.
    • (2000) Science , vol.288 , pp. 2351-2354
    • Chan, F.K.1    Chun, H.J.2    Zheng, L.3    Siegel, R.M.4    Bui, K.L.5    Lenardo, M.J.6
  • 13
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema J.P., Scaffidi C., Kischkel F.C., Shevchenko A., Mann M., Krammer P.H., et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997, 16:2794-2804.
    • (1997) EMBO J , vol.16 , pp. 2794-2804
    • Medema, J.P.1    Scaffidi, C.2    Kischkel, F.C.3    Shevchenko, A.4    Mann, M.5    Krammer, P.H.6
  • 14
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: signaling and modulation
    • Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science 1998, 281:1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 16
    • 77955930419 scopus 로고    scopus 로고
    • Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations
    • Bavi P., Prabhakaran S.E., Abubaker J., Qadri Z., George T., Al-Sanea N., et al. Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations. Mol Cancer 2010, 9:203-216.
    • (2010) Mol Cancer , vol.9 , pp. 203-216
    • Bavi, P.1    Prabhakaran, S.E.2    Abubaker, J.3    Qadri, Z.4    George, T.5    Al-Sanea, N.6
  • 17
    • 34548695886 scopus 로고    scopus 로고
    • TRAIL death receptor-4 expression positively correlates with the tumor grade in breast cancer patients with invasive ductal carcinoma
    • Sanlioglu A.D., Korcum A.F., Pestereli E., Erdogan G., Karaveli S., Savas B., et al. TRAIL death receptor-4 expression positively correlates with the tumor grade in breast cancer patients with invasive ductal carcinoma. Int J Radiat Oncol Biol Phys 2007, 69:716-723.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 716-723
    • Sanlioglu, A.D.1    Korcum, A.F.2    Pestereli, E.3    Erdogan, G.4    Karaveli, S.5    Savas, B.6
  • 18
  • 19
    • 77952912435 scopus 로고    scopus 로고
    • Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types
    • Kaplan-Lefko P.J., Graves J.D., Zoog S.J., Pan Y., Wall J., Branstetter D.G., et al. Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types. Cancer Biol Ther 2010, 9:618-631.
    • (2010) Cancer Biol Ther , vol.9 , pp. 618-631
    • Kaplan-Lefko, P.J.1    Graves, J.D.2    Zoog, S.J.3    Pan, Y.4    Wall, J.5    Branstetter, D.G.6
  • 20
    • 80054710238 scopus 로고    scopus 로고
    • Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors
    • Doi T., Murakami H., Ohtsu A., Fuse N., Yoshino T., Yamamoto N., et al. Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors. Cancer Chemother Pharmacol 2010, 10:1544-1551.
    • (2010) Cancer Chemother Pharmacol , vol.10 , pp. 1544-1551
    • Doi, T.1    Murakami, H.2    Ohtsu, A.3    Fuse, N.4    Yoshino, T.5    Yamamoto, N.6
  • 21
    • 78650340456 scopus 로고    scopus 로고
    • A first-in-human study of conatumumab in adult patients with advanced solid tumors
    • Herbst R.S., Kurzrock R., Hong D.S., Valdivieso M., Hsu C.P., Goyal L., et al. A first-in-human study of conatumumab in adult patients with advanced solid tumors. Clin Cancer Res 2010, 16:5883-5891.
    • (2010) Clin Cancer Res , vol.16 , pp. 5883-5891
    • Herbst, R.S.1    Kurzrock, R.2    Hong, D.S.3    Valdivieso, M.4    Hsu, C.P.5    Goyal, L.6
  • 24
    • 38049178647 scopus 로고    scopus 로고
    • Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles
    • Scott C.J., Marouf W.M., Quinn D.J., Buick R.J., Orr S.J., Donnelly R.F., et al. Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles. Pharm Res 2008, 25:135-146.
    • (2008) Pharm Res , vol.25 , pp. 135-146
    • Scott, C.J.1    Marouf, W.M.2    Quinn, D.J.3    Buick, R.J.4    Orr, S.J.5    Donnelly, R.F.6
  • 25
    • 56749163384 scopus 로고    scopus 로고
    • Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality
    • McCarron P.A., Marouf W.M., Donnelly R.F., Scott C. Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality. J Biomed Mater Res A 2008, 87:873-884.
    • (2008) J Biomed Mater Res A , vol.87 , pp. 873-884
    • McCarron, P.A.1    Marouf, W.M.2    Donnelly, R.F.3    Scott, C.4
  • 26
    • 30344452318 scopus 로고    scopus 로고
    • Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP
    • Galligan L., Longley D.B., McEwan M., Wilson T.R., McLaughlin K., Johnston P.G. Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP. Mol Cancer Ther 2005, 4:2026-2036.
    • (2005) Mol Cancer Ther , vol.4 , pp. 2026-2036
    • Galligan, L.1    Longley, D.B.2    McEwan, M.3    Wilson, T.R.4    McLaughlin, K.5    Johnston, P.G.6
  • 27
    • 77649275788 scopus 로고    scopus 로고
    • Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles
    • Fay F., Quinn D.J., Gilmore B.F., McCarron P.A., Scott C.J. Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles. Biomaterials 2010, 31:4214-4222.
    • (2010) Biomaterials , vol.31 , pp. 4214-4222
    • Fay, F.1    Quinn, D.J.2    Gilmore, B.F.3    McCarron, P.A.4    Scott, C.J.5
  • 28
    • 0034765888 scopus 로고    scopus 로고
    • Calcein-acetyoxymethyl cytotoxicity assay: standardization of a method allowing additional analyses on recovered effector cells and supernatants
    • Neri S., Mariani E., Meneghetti A., Cattini L., Facchini A. Calcein-acetyoxymethyl cytotoxicity assay: standardization of a method allowing additional analyses on recovered effector cells and supernatants. Clin Diagn Lab Immunol 2001, 8:1131-1135.
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 1131-1135
    • Neri, S.1    Mariani, E.2    Meneghetti, A.3    Cattini, L.4    Facchini, A.5
  • 30
    • 0024358188 scopus 로고
    • DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
    • Giovanella B.C., Stehlin J.S., Wall M.E., Wani M.C., Nicholas A.W., Liu L.F., et al. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989, 246:1046-1048.
    • (1989) Science , vol.246 , pp. 1046-1048
    • Giovanella, B.C.1    Stehlin, J.S.2    Wall, M.E.3    Wani, M.C.4    Nicholas, A.W.5    Liu, L.F.6
  • 31
    • 0029661932 scopus 로고    scopus 로고
    • Correlations between S and G2 arrest and the cytotoxicity of camptothecin in human colon carcinoma cells
    • Goldwasser F., Shimizu T., Jackman J., Hoki Y., O'Connor P.M., Kohn K.W., et al. Correlations between S and G2 arrest and the cytotoxicity of camptothecin in human colon carcinoma cells. Cancer Res 1996, 56:4430-4437.
    • (1996) Cancer Res , vol.56 , pp. 4430-4437
    • Goldwasser, F.1    Shimizu, T.2    Jackman, J.3    Hoki, Y.4    O'Connor, P.M.5    Kohn, K.W.6
  • 32
    • 0034630161 scopus 로고    scopus 로고
    • The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
    • Walczak H., Krammer P.H. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 2000, 256:58-66.
    • (2000) Exp Cell Res , vol.256 , pp. 58-66
    • Walczak, H.1    Krammer, P.H.2
  • 34
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H., Miller R.E., Ariail K., Gliniak B., Griffith T.S., Kubin M., et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999, 5:157-163.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3    Gliniak, B.4    Griffith, T.S.5    Kubin, M.6
  • 35
    • 0034812659 scopus 로고    scopus 로고
    • Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety
    • Kelley S.K., Harris L.A., Xie D., Deforge L., Totpal K., Bussiere J., et al. Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety. J Pharmacol Exp Ther 2001, 299:31-38.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 31-38
    • Kelley, S.K.1    Harris, L.A.2    Xie, D.3    Deforge, L.4    Totpal, K.5    Bussiere, J.6
  • 36
    • 0036792685 scopus 로고    scopus 로고
    • TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy
    • Wajant H., Pfizenmaier K., Scheurich P. TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy. Apoptosis 2002, 7:449-459.
    • (2002) Apoptosis , vol.7 , pp. 449-459
    • Wajant, H.1    Pfizenmaier, K.2    Scheurich, P.3
  • 37
    • 0033210894 scopus 로고    scopus 로고
    • Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review)
    • Bonavida B., Ng C.P., Jazirehi A., Schiller G., Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review). Int J Oncol 1999, 15:793-802.
    • (1999) Int J Oncol , vol.15 , pp. 793-802
    • Bonavida, B.1    Ng, C.P.2    Jazirehi, A.3    Schiller, G.4    Mizutani, Y.5
  • 38
    • 2942565827 scopus 로고    scopus 로고
    • Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications
    • Shankar S., Srivastava R.K. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist Updat 2004, 7:139-156.
    • (2004) Drug Resist Updat , vol.7 , pp. 139-156
    • Shankar, S.1    Srivastava, R.K.2
  • 39
    • 0033572413 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11
    • Gliniak B., Le T. Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res 1999, 59:6153-6158.
    • (1999) Cancer Res , vol.59 , pp. 6153-6158
    • Gliniak, B.1    Le, T.2
  • 40
    • 52649109068 scopus 로고    scopus 로고
    • The TRAIL apoptotic pathway in cancer onset, progression and therapy
    • Johnstone R.W., Frew A.J., Smyth M.J. The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat Rev Cancer 2008, 8:782-798.
    • (2008) Nat Rev Cancer , vol.8 , pp. 782-798
    • Johnstone, R.W.1    Frew, A.J.2    Smyth, M.J.3
  • 41
    • 40949138762 scopus 로고    scopus 로고
    • Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5
    • Adams C., Totpal K., Lawrence D., Marsters S., Pitti R., Yee S., et al. Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ 2008, 15:751-761.
    • (2008) Cell Death Differ , vol.15 , pp. 751-761
    • Adams, C.1    Totpal, K.2    Lawrence, D.3    Marsters, S.4    Pitti, R.5    Yee, S.6
  • 42
    • 33646403907 scopus 로고    scopus 로고
    • Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo
    • Zeng Y., Wu X.X., Fiscella M., Shimada O., Humphreys R., Albert V., et al. Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo. Int J Oncol 2006, 28:421-430.
    • (2006) Int J Oncol , vol.28 , pp. 421-430
    • Zeng, Y.1    Wu, X.X.2    Fiscella, M.3    Shimada, O.4    Humphreys, R.5    Albert, V.6
  • 43
    • 76649140507 scopus 로고    scopus 로고
    • Drug-free macromolecular therapeutics: induction of apoptosis by coiled-coil-mediated cross-linking of antigens on the cell surface
    • Wu K., Liu J., Johnson R.N., Yang J., Kopecek J. Drug-free macromolecular therapeutics: induction of apoptosis by coiled-coil-mediated cross-linking of antigens on the cell surface. Angew Chem Int Ed Engl 2010, 49:1451-1455.
    • (2010) Angew Chem Int Ed Engl , vol.49 , pp. 1451-1455
    • Wu, K.1    Liu, J.2    Johnson, R.N.3    Yang, J.4    Kopecek, J.5
  • 44
    • 40449122796 scopus 로고    scopus 로고
    • Nanoparticle-mediated cellular response is size-dependent
    • Jiang W., Kim B.Y., Rutka J.T., Chan W.C. Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol 2008, 3:145-150.
    • (2008) Nat Nanotechnol , vol.3 , pp. 145-150
    • Jiang, W.1    Kim, B.Y.2    Rutka, J.T.3    Chan, W.C.4
  • 45
    • 0027096415 scopus 로고
    • A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues
    • Fassberg J., Stella V.J. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues. J Pharm Sci 1992, 81:676-684.
    • (1992) J Pharm Sci , vol.81 , pp. 676-684
    • Fassberg, J.1    Stella, V.J.2
  • 46
    • 0028267240 scopus 로고
    • Camptothecins: from bench research to hospital wards
    • Potmesil M. Camptothecins: from bench research to hospital wards. Cancer Res 1994, 54:1431-1439.
    • (1994) Cancer Res , vol.54 , pp. 1431-1439
    • Potmesil, M.1
  • 47
    • 33749028208 scopus 로고    scopus 로고
    • A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-alpha inhibitor
    • Yang X.X., Hu Z.P., Xu A.L., Duan W., Zhu Y.Z., Huang M., et al. A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-alpha inhibitor. J Pharmacol Exp Ther 2006, 319:82-104.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 82-104
    • Yang, X.X.1    Hu, Z.P.2    Xu, A.L.3    Duan, W.4    Zhu, Y.Z.5    Huang, M.6
  • 48
    • 67650359893 scopus 로고    scopus 로고
    • Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models
    • Numbenjapon T., Wang J., Colcher D., Schluep T., Davis M.E., Duringer J., et al. Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models. ClinCancer Res 2009, 15:4365-4373.
    • (2009) ClinCancer Res , vol.15 , pp. 4365-4373
    • Numbenjapon, T.1    Wang, J.2    Colcher, D.3    Schluep, T.4    Davis, M.E.5    Duringer, J.6
  • 49
    • 34547838187 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs
    • Lu J., Liong M., Zink J.I., Tamanoi F. Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small 2007, 3:1341-1346.
    • (2007) Small , vol.3 , pp. 1341-1346
    • Lu, J.1    Liong, M.2    Zink, J.I.3    Tamanoi, F.4
  • 50
    • 33745494861 scopus 로고    scopus 로고
    • Camptothecin in sterically stabilized phospholipid micelles: a novel nanomedicine
    • Koo O.M., Rubinstein I., Onyuksel H. Camptothecin in sterically stabilized phospholipid micelles: a novel nanomedicine. Nanomedicine 2005, 1:77-84.
    • (2005) Nanomedicine , vol.1 , pp. 77-84
    • Koo, O.M.1    Rubinstein, I.2    Onyuksel, H.3
  • 51
    • 35349015328 scopus 로고    scopus 로고
    • Stealth and non-stealth nanocapsules containing camptothecin: in-vitro and in-vivo activity on B16-F10 melanoma
    • Loch-Neckel G., Nemen D., Puhl A.C., Fernandes D., Stimamiglio M.A., Alvarez Silva M., et al. Stealth and non-stealth nanocapsules containing camptothecin: in-vitro and in-vivo activity on B16-F10 melanoma. J Pharm Pharmacol 2007, 59:1359-1364.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 1359-1364
    • Loch-Neckel, G.1    Nemen, D.2    Puhl, A.C.3    Fernandes, D.4    Stimamiglio, M.A.5    Alvarez Silva, M.6
  • 52
    • 34250810241 scopus 로고    scopus 로고
    • Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin
    • Kunii R., Onishi H., Machida Y. Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin. Eur J Pharm Biopharm 2007, 67:9-17.
    • (2007) Eur J Pharm Biopharm , vol.67 , pp. 9-17
    • Kunii, R.1    Onishi, H.2    Machida, Y.3
  • 53
    • 68549136478 scopus 로고    scopus 로고
    • Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery
    • Liu J., Jiang Z., Zhang S., Saltzman W.M. Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery. Biomaterials 2009, 30:5707-5719.
    • (2009) Biomaterials , vol.30 , pp. 5707-5719
    • Liu, J.1    Jiang, Z.2    Zhang, S.3    Saltzman, W.M.4
  • 55
    • 0345598868 scopus 로고    scopus 로고
    • Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy
    • Wang S., El-Deiry W.S. Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. Proc Natl Acad Sci U S A 2003, 100:15095-15100.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15095-15100
    • Wang, S.1    El-Deiry, W.S.2
  • 56
    • 34248221595 scopus 로고    scopus 로고
    • S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells
    • Ray S., Shyam S., Fraizer G.C., Almasan A. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells. Mol Cancer Ther 2007, 6:1368-1378.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1368-1378
    • Ray, S.1    Shyam, S.2    Fraizer, G.C.3    Almasan, A.4
  • 57
    • 40649100957 scopus 로고    scopus 로고
    • Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice
    • Kim J.H., Kim Y.S., Park K., Lee S., Nam H.Y., Min K.H., et al. Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice. J Control Release 2008, 127:41-49.
    • (2008) J Control Release , vol.127 , pp. 41-49
    • Kim, J.H.1    Kim, Y.S.2    Park, K.3    Lee, S.4    Nam, H.Y.5    Min, K.H.6
  • 58
    • 78349308005 scopus 로고    scopus 로고
    • Targeting of polymeric nanoparticles to lung metastases by surface-attachment of YIGSR peptide from laminin
    • Sarfati G., Dvir T., Elkabets M., Apte R.N., Cohen S. Targeting of polymeric nanoparticles to lung metastases by surface-attachment of YIGSR peptide from laminin. Biomaterials 2011, 32:152-161.
    • (2011) Biomaterials , vol.32 , pp. 152-161
    • Sarfati, G.1    Dvir, T.2    Elkabets, M.3    Apte, R.N.4    Cohen, S.5
  • 59
    • 20444375424 scopus 로고    scopus 로고
    • Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes
    • Dinauer N., Balthasar S., Weber C., Kreuter J., Langer K., von Briesen H. Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes. Biomaterials 2005, 26:5898-5906.
    • (2005) Biomaterials , vol.26 , pp. 5898-5906
    • Dinauer, N.1    Balthasar, S.2    Weber, C.3    Kreuter, J.4    Langer, K.5    von Briesen, H.6
  • 60
    • 74449089443 scopus 로고    scopus 로고
    • Enhanced drug targeting by attachment of an anti alphav integrin antibody to doxorubicin loaded human serum albumin nanoparticles
    • Wagner S., Rothweiler F., Anhorn M.G., Sauer D., Riemann I., Weiss E.C., et al. Enhanced drug targeting by attachment of an anti alphav integrin antibody to doxorubicin loaded human serum albumin nanoparticles. Biomaterials 2010, 31:2388-2398.
    • (2010) Biomaterials , vol.31 , pp. 2388-2398
    • Wagner, S.1    Rothweiler, F.2    Anhorn, M.G.3    Sauer, D.4    Riemann, I.5    Weiss, E.C.6
  • 61
    • 68749092564 scopus 로고    scopus 로고
    • Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy
    • Acharya S., Dilnawaz F., Sahoo S.K. Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy. Biomaterials 2009, 30:5737-5750.
    • (2009) Biomaterials , vol.30 , pp. 5737-5750
    • Acharya, S.1    Dilnawaz, F.2    Sahoo, S.K.3
  • 62
    • 34547891537 scopus 로고    scopus 로고
    • Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes
    • Hatakeyama H., Akita H., Ishida E., Hashimoto K., Kobayashi H., Aoki T., et al. Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes. Int J Pharm 2007, 342:194-200.
    • (2007) Int J Pharm , vol.342 , pp. 194-200
    • Hatakeyama, H.1    Akita, H.2    Ishida, E.3    Hashimoto, K.4    Kobayashi, H.5    Aoki, T.6
  • 63
    • 77649271933 scopus 로고    scopus 로고
    • Development of a bifunctional immunoliposome system for combined drug delivery and imaging in vivo
    • Feng B., Tomizawa K., Michiue H., Han X.J., Miyatake S., Matsui H. Development of a bifunctional immunoliposome system for combined drug delivery and imaging in vivo. Biomaterials 2010, 31:4139-4145.
    • (2010) Biomaterials , vol.31 , pp. 4139-4145
    • Feng, B.1    Tomizawa, K.2    Michiue, H.3    Han, X.J.4    Miyatake, S.5    Matsui, H.6
  • 64
    • 61649110773 scopus 로고    scopus 로고
    • Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells
    • Eghtedari M., Liopo A.V., Copland J.A., Oraevsky A.A., Motamedi M. Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells. Nano Lett 2009, 9:287-291.
    • (2009) Nano Lett , vol.9 , pp. 287-291
    • Eghtedari, M.1    Liopo, A.V.2    Copland, J.A.3    Oraevsky, A.A.4    Motamedi, M.5


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