-
3
-
-
69149084667
-
Primary liver tumors: Origin and target therapy
-
Papoulas M, Theocharis S. Primary liver tumors: Origin and target therapy. Expert Opin Ther Targets 2009; 13: 957-965.
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 957-965
-
-
Papoulas, M.1
Theocharis, S.2
-
4
-
-
77949891635
-
Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma
-
Zhu Z, Hao X, Yan M, et al. Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma. Int J Cancer 2010; 126: 2067-2078.
-
(2010)
Int J Cancer
, vol.126
, pp. 2067-2078
-
-
Zhu, Z.1
Hao, X.2
Yan, M.3
-
5
-
-
73249127416
-
Cancer stem cells and hepatocellular carcinoma
-
Yao Z, Mishra L. Cancer stem cells and hepatocellular carcinoma. Cancer Biol Ther 2009; 8: 1691-1698.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1691-1698
-
-
Yao, Z.1
Mishra, L.2
-
6
-
-
77952564300
-
The identification of stem cells in human liver diseases and hepatocellular carcinoma
-
Oliva J, French BA, Qing X, French SW. The identification of stem cells in human liver diseases and hepatocellular carcinoma. Exp Mol Pathol 2010; 88: 331-340.
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 331-340
-
-
Oliva, J.1
French, B.A.2
Qing, X.3
French, S.W.4
-
8
-
-
77957353560
-
Liver stem/progenitor cells in the canals of Hering: Cellular origin of hepatocellular carcinoma with bile duct tumor thrombi?
-
Peng N, Li L, Cai X, Tan S, Wu T. Liver stem/progenitor cells in the canals of Hering: Cellular origin of hepatocellular carcinoma with bile duct tumor thrombi? Stem Cell Rev 2010; 6: 579-584.
-
(2010)
Stem Cell Rev
, vol.6
, pp. 579-584
-
-
Peng, N.1
Li, L.2
Cai, X.3
Tan, S.4
Wu, T.5
-
9
-
-
77953693531
-
Molecular classification of hepatocellular carcinoma
-
Zucman-Rossi J. Molecular classification of hepatocellular carcinoma. Dig Liver Dis 2010; 42: S235-S241.
-
(2010)
Dig Liver Dis
, vol.42
-
-
Zucman-Rossi, J.1
-
10
-
-
77955388300
-
Effects of the TP53p. R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: Interaction with hepatitis B virus X protein
-
Gouas DA, Shi H, Hautefeuille AH, et al. Effects of the TP53p. R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: Interaction with hepatitis B virus X protein. Carcinogenesis 2010; 31: 1475-1482.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1475-1482
-
-
Gouas, D.A.1
Shi, H.2
Hautefeuille, A.H.3
-
11
-
-
9844262261
-
The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene
-
Isfort RJ, Cody DB, Doersen CJ, et al. The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene. Oncogene 1997; 15: 1797-1803.
-
(1997)
Oncogene
, vol.15
, pp. 1797-1803
-
-
Isfort, R.J.1
Cody, D.B.2
Doersen, C.J.3
-
12
-
-
33947322678
-
The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells
-
Robert A, Margall-Ducos G, Guidotti JE, et al. The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells. J Cell Sci 2007; 120: 628-637.
-
(2007)
J Cell Sci
, vol.120
, pp. 628-637
-
-
Robert, A.1
Margall-Ducos, G.2
Guidotti, J.E.3
-
13
-
-
78149421791
-
Loss of heterozygosity of the tumor suppressor gene Tg737 in the side population cells of hepatocellular carcinomas is associated with poor prognosis
-
Song Z, Li R, You N, Tao K, Dou K. Loss of heterozygosity of the tumor suppressor gene Tg737 in the side population cells of hepatocellular carcinomas is associated with poor prognosis. Mol Biol Rep 2010; 37: 4091-4101.
-
(2010)
Mol Biol Rep
, vol.37
, pp. 4091-4101
-
-
Song, Z.1
Li, R.2
You, N.3
Tao, K.4
Dou, K.5
-
14
-
-
78751643724
-
Convenient and efficient enrichment of the CD133+ liver cells from rat fetal liver cells as a source of liver stem/progenitor cells
-
Liu WH, Li R, Dou KF. Convenient and efficient enrichment of the CD133+ liver cells from rat fetal liver cells as a source of liver stem/progenitor cells. Stem Cell Rev 2011; 7: 94-102.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 94-102
-
-
Liu, W.H.1
Li, R.2
Dou, K.F.3
-
15
-
-
34548781396
-
Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies
-
Zucman-Rossi J, Laurent-Puig P. Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies. Pharmacogenomics 2007; 8: 997-1003.
-
(2007)
Pharmacogenomics
, vol.8
, pp. 997-1003
-
-
Zucman-Rossi, J.1
Laurent-Puig, P.2
-
16
-
-
77954366963
-
Molecular targets for liver cancer therapy: From screening of target genes to clinical trials
-
Midorikawa Y, Sugiyama Y, Aburatani H. Molecular targets for liver cancer therapy: From screening of target genes to clinical trials. Hepatol Res 2009; 40: 49-60.
-
(2009)
Hepatol Res
, vol.40
, pp. 49-60
-
-
Midorikawa, Y.1
Sugiyama, Y.2
Aburatani, H.3
-
17
-
-
77951640416
-
Comparison of gene expression in hepatocellular carcinoma, liver development, and liver regeneration
-
Li T, Wan B, Huang J, Zhang X. Comparison of gene expression in hepatocellular carcinoma, liver development, and liver regeneration. Mol Genet Genomics 2010; 283: 485-492.
-
(2010)
Mol Genet Genomics
, vol.283
, pp. 485-492
-
-
Li, T.1
Wan, B.2
Huang, J.3
Zhang, X.4
-
18
-
-
79952043062
-
Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad
-
Nejak-Bowen KN, Monga SP. Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad. Semin Cancer Biol 2011; 21: 44-58.
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 44-58
-
-
Nejak-Bowen, K.N.1
Monga, S.P.2
-
19
-
-
10744233450
-
Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice
-
Kato T, Miyamoto M, Date T, et al. Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice. Cancer Sci 2003; 94: 679-685.
-
(2003)
Cancer Sci
, vol.94
, pp. 679-685
-
-
Kato, T.1
Miyamoto, M.2
Date, T.3
-
20
-
-
77954000738
-
Collecting evidence for a stem cell hypothesis in HCC
-
Teufel A, Galle PR. Collecting evidence for a stem cell hypothesis in HCC. Gut 2010; 59: 870-871.
-
(2010)
Gut
, vol.59
, pp. 870-871
-
-
Teufel, A.1
Galle, P.R.2
-
21
-
-
33745220772
-
Origin of hepatocellular carcinoma: Role of stem cells
-
Wu XZ, Chen D. Origin of hepatocellular carcinoma: Role of stem cells. J Gastroenterol Hepatol 2006; 21: 1093-1098.
-
(2006)
J Gastroenterol Hepatol
, vol.21
, pp. 1093-1098
-
-
Wu, X.Z.1
Chen, D.2
-
22
-
-
33745924696
-
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
-
Chiba T, Kita K, Zheng YW, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology 2006; 44: 240-251.
-
(2006)
Hepatology
, vol.44
, pp. 240-251
-
-
Chiba, T.1
Kita, K.2
Zheng, Y.W.3
-
24
-
-
28444449065
-
Liver stem cells: Implications for hepatocarcinogenesis
-
Alison MR. Liver stem cells: Implications for hepatocarcinogenesis. Stem Cell Rev 2005; 1: 253-260.
-
(2005)
Stem Cell Rev
, vol.1
, pp. 253-260
-
-
Alison, M.R.1
-
25
-
-
9444265320
-
Gastric cancer originating from bone marrow-derived cells
-
Houghton J, Stoicov C, Nomura S, et al. Gastric cancer originating from bone marrow-derived cells. Science 2004; 306: 1568-1571.
-
(2004)
Science
, vol.306
, pp. 1568-1571
-
-
Houghton, J.1
Stoicov, C.2
Nomura, S.3
-
27
-
-
78650520052
-
The Wnt/beta-catenin pathway in adrenocortical development and cancer
-
El Wakil A, Lalli E. The Wnt/beta-catenin pathway in adrenocortical development and cancer. Mol Cell Endocrinol 2011; 332: 32-37.
-
(2011)
Mol Cell Endocrinol
, vol.332
, pp. 32-37
-
-
El Wakil, A.1
Lalli, E.2
-
28
-
-
79955030842
-
Breast cancer stem cells: A new challenge for breast cancer treatment
-
Jain P, Alahari SK. Breast cancer stem cells: A new challenge for breast cancer treatment. Front Biosci 2011; 16: 1824-1832.
-
(2011)
Front Biosci
, vol.16
, pp. 1824-1832
-
-
Jain, P.1
Alahari, S.K.2
-
29
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 2011; 8: 97-106.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
Ivy, S.P.4
-
30
-
-
34548706039
-
Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model
-
Tang B, Yoo N, Vu M, et al. Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model. Cancer Res 2007; 67: 8643-8652.
-
(2007)
Cancer Res
, vol.67
, pp. 8643-8652
-
-
Tang, B.1
Yoo, N.2
Vu, M.3
-
32
-
-
77956297820
-
Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate
-
Zhao X, Malhotra GK, Lele SM, et al. Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate. Proc Natl Acad Sci USA 2010; 107: 14146-14151.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14146-14151
-
-
Zhao, X.1
Malhotra, G.K.2
Lele, S.M.3
-
33
-
-
37749017645
-
The CDK inhibitors: Potential targets for therapeutic stem cell manipulations?
-
Boyer MJ, Cheng T. The CDK inhibitors: Potential targets for therapeutic stem cell manipulations? Gene Ther 2008; 15: 117-125.
-
(2008)
Gene Ther
, vol.15
, pp. 117-125
-
-
Boyer, M.J.1
Cheng, T.2
-
34
-
-
76049120037
-
Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation
-
Lieu YK, Reddy EP. Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation. Proc Natl Acad Sci USA 2009; 106: 21689-21694.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21689-21694
-
-
Lieu, Y.K.1
Reddy, E.P.2
-
35
-
-
77957790353
-
The Myc connection: ES cells and cancer
-
Rothenberg ME, Clarke MF, Diehn M. The Myc connection: ES cells and cancer. Cell 2010; 143: 184-186.
-
(2010)
Cell
, vol.143
, pp. 184-186
-
-
Rothenberg, M.E.1
Clarke, M.F.2
Diehn, M.3
-
36
-
-
77950677122
-
Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension
-
Steiner D, Khaner H, Cohen M, et al. Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension. Nat Biotechnol 2010; 28: 361-364.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 361-364
-
-
Steiner, D.1
Khaner, H.2
Cohen, M.3
-
37
-
-
72149084678
-
Proliferative drive and liver carcinogenesis: Too much of a good thing?
-
Teoh NC. Proliferative drive and liver carcinogenesis: Too much of a good thing? J Gastroenterol Hepatol 2009; 24: 1817-1825.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 1817-1825
-
-
Teoh, N.C.1
-
38
-
-
0027202321
-
Cell cycle control, DNA repair and initiation of carcinogenesis
-
Kaufmann WK, Kaufman DG. Cell cycle control, DNA repair and initiation of carcinogenesis. FASEB J 1993; 7: 1188-1191.
-
(1993)
FASEB J
, vol.7
, pp. 1188-1191
-
-
Kaufmann, W.K.1
Kaufman, D.G.2
-
39
-
-
49649118828
-
Cell cycle machinery: Links with genesis and treatment of breast cancer
-
Butt AJ, Caldon CE, McNeil CM, Swarbrick A, Musgrove EA, Sutherland RL. Cell cycle machinery: Links with genesis and treatment of breast cancer. Adv Exp Med Biol 2008; 630: 189-205.
-
(2008)
Adv Exp Med Biol
, vol.630
, pp. 189-205
-
-
Butt, A.J.1
Caldon, C.E.2
McNeil, C.M.3
Swarbrick, A.4
Musgrove, E.A.5
Sutherland, R.L.6
-
40
-
-
78649767501
-
CCAAT/enhancer binding protein-delta (C/EBP-delta) regulates cell growth, migration and differentiation
-
Yu X, Si J, Zhang Y, Dewille JW. CCAAT/enhancer binding protein-delta (C/EBP-delta) regulates cell growth, migration and differentiation. Cancer Cell Int 2010; 10: 48.
-
(2010)
Cancer Cell Int
, vol.10
, pp. 48
-
-
Yu, X.1
Si, J.2
Zhang, Y.3
Dewille, J.W.4
-
41
-
-
79957501076
-
Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells inhibits cell proliferation by inducing cell cycle arrest in the G0/G1 phase
-
Wang T, Hao L, Feng Y, Wang G, Qin D, Gu G. Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells inhibits cell proliferation by inducing cell cycle arrest in the G0/G1 phase. Oncol Res 2011; 19: 193-201.
-
(2011)
Oncol Res
, vol.19
, pp. 193-201
-
-
Wang, T.1
Hao, L.2
Feng, Y.3
Wang, G.4
Qin, D.5
Gu, G.6
-
42
-
-
0037103988
-
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells
-
Jirmanova L, Afanassieff M, Gobert-Gosse S, Markossian S, Savatier P. Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene 2002; 21: 5515-5528.
-
(2002)
Oncogene
, vol.21
, pp. 5515-5528
-
-
Jirmanova, L.1
Afanassieff, M.2
Gobert-Gosse, S.3
Markossian, S.4
Savatier, P.5
-
43
-
-
77951922194
-
Adenosine induces G2/M cell-cycle arrest by inhibiting cell mitosis progression
-
Jia KZ, Tang B, Yu L, et al. Adenosine induces G2/M cell-cycle arrest by inhibiting cell mitosis progression. Cell Biol Int 2009; 34: 49-52.
-
(2009)
Cell Biol Int
, vol.34
, pp. 49-52
-
-
Jia, K.Z.1
Tang, B.2
Yu, L.3
-
44
-
-
34547972650
-
Selective tropism of liver stem cells to hepatocellular carcinoma in vivo
-
Zhong XG, He S, Yin W, Deng JY, Cheng B. Selective tropism of liver stem cells to hepatocellular carcinoma in vivo. World J Gastroenterol 2007; 13: 3886-3891.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 3886-3891
-
-
Zhong, X.G.1
He, S.2
Yin, W.3
Deng, J.Y.4
Cheng, B.5
-
45
-
-
67650469849
-
Liver cancer stem cells: Implications for a new therapeutic target
-
Lee TK, Castilho A, Ma S, Ng IO. Liver cancer stem cells: Implications for a new therapeutic target. Liver Int 2009; 29: 955-965.
-
(2009)
Liver Int
, vol.29
, pp. 955-965
-
-
Lee, T.K.1
Castilho, A.2
Ma, S.3
Ng, I.O.4
-
46
-
-
79952111472
-
Examining the metastatic niche: Targeting the microenvironment
-
Guise T. Examining the metastatic niche: Targeting the microenvironment. Semin Oncol 2010; 37: S2-S14.
-
(2010)
Semin Oncol
, vol.37
-
-
Guise, T.1
-
47
-
-
77953782543
-
The stem cell niche in health and malignancy
-
Burness ML, Sipkins DA. The stem cell niche in health and malignancy. Semin Cancer Biol 2010; 20: 107-115.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 107-115
-
-
Burness, M.L.1
Sipkins, D.A.2
-
49
-
-
34548471937
-
Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation
-
Chiba T, Zheng YW, Kita K, et al. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation. Gastroenterology 2007; 133: 937-950.
-
(2007)
Gastroenterology
, vol.133
, pp. 937-950
-
-
Chiba, T.1
Zheng, Y.W.2
Kita, K.3
-
50
-
-
77956637856
-
Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice
-
Chiba T, Seki A, Aoki R, et al. Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice. Hepatology 2010; 52: 1111-1123.
-
(2010)
Hepatology
, vol.52
, pp. 1111-1123
-
-
Chiba, T.1
Seki, A.2
Aoki, R.3
|