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Volumn 107, Issue 32, 2010, Pages 14146-14151

Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate

Author keywords

Immortalization; In vitro stem cell model; Mammary epithelial cells; Selfrenewal; Stem cell

Indexed keywords

NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; WNT PROTEIN; BIOLOGICAL MARKER; TELOMERASE;

EID: 77956297820     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009030107     Document Type: Article
Times cited : (48)

References (45)
  • 1
    • 67650741782 scopus 로고    scopus 로고
    • Management of breast cancer in the genome era
    • Morrow PK, Hortobagyi GN (2009) Management of breast cancer in the genome era. Annu Rev Med 60:153-165.
    • (2009) Annu Rev Med , vol.60 , pp. 153-165
    • Morrow, P.K.1    Hortobagyi, G.N.2
  • 2
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98:10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1
  • 3
    • 60149109533 scopus 로고    scopus 로고
    • Looking ahead in cancer stem cell research
    • Dick JE (2009) Looking ahead in cancer stem cell research. Nat Biotechnol 27:44-46.
    • (2009) Nat Biotechnol , vol.27 , pp. 44-46
    • Dick, J.E.1
  • 4
    • 0035177216 scopus 로고    scopus 로고
    • Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    • Elenbaas B, et al. (2001) Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev 15:50-65.
    • (2001) Genes Dev , vol.15 , pp. 50-65
    • Elenbaas, B.1
  • 5
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 6
    • 0024512996 scopus 로고
    • Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types
    • Band V, Sager R (1989) Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc Natl Acad Sci USA 86:1249-1253.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1249-1253
    • Band, V.1    Sager, R.2
  • 7
    • 0025023538 scopus 로고
    • Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements
    • Band V, Zajchowski D, Kulesa V, Sager R (1990) Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements. Proc Natl Acad Sci USA 87:463-467.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 463-467
    • Band, V.1    Zajchowski, D.2    Kulesa, V.3    Sager, R.4
  • 8
    • 0029312549 scopus 로고
    • Preneoplastic transformation of human mammary epithelial cells
    • Band V (1995) Preneoplastic transformation of human mammary epithelial cells. Semin Cancer Biol 6:185-192.
    • (1995) Semin Cancer Biol , vol.6 , pp. 185-192
    • Band, V.1
  • 9
    • 9744270333 scopus 로고    scopus 로고
    • In vitro models of early neoplastic transformation of human mammary epithelial cells
    • Band V (2003) In vitro models of early neoplastic transformation of human mammary epithelial cells. Methods Mol Biol 223:237-248.
    • (2003) Methods Mol Biol , vol.223 , pp. 237-248
    • Band, V.1
  • 10
    • 58349090028 scopus 로고    scopus 로고
    • Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells
    • Zhao X, et al. (2009) Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells. Cancer Res 69:483-491.
    • (2009) Cancer Res , vol.69 , pp. 483-491
    • Zhao, X.1
  • 12
    • 0029005279 scopus 로고
    • Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7
    • Wazer DE, Liu XL, Chu Q, Gao Q, Band V (1995) Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7. Proc Natl Acad Sci USA 92:3687-3691.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3687-3691
    • Wazer, D.E.1    Liu, X.L.2    Chu, Q.3    Gao, Q.4    Band, V.5
  • 16
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, et al. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1
  • 19
    • 33845982922 scopus 로고    scopus 로고
    • Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
    • Sleeman KE, et al. (2007) Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol 176:19-26.
    • (2007) J Cell Biol , vol.176 , pp. 19-26
    • Sleeman, K.E.1
  • 20
    • 33746709476 scopus 로고    scopus 로고
    • Steroid hormone receptor status of mouse mammary stem cells
    • Asselin-Labat ML, et al. (2006) Steroid hormone receptor status of mouse mammary stem cells. J Natl Cancer Inst 98:1011-1014.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1011-1014
    • Asselin-Labat, M.L.1
  • 21
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J, et al. (2006) Purification and unique properties of mammary epithelial stem cells. Nature 439:993-997.
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1
  • 22
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • DOI 10.1186/bcr1021, 86
    • Liu S, Dontu G, Wicha MS (2005) Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res 7:86-95. (Pubitemid 40704127)
    • (2005) Breast Cancer Research , vol.7 , Issue.3 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 23
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1:555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1
  • 24
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, et al. (2009) Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 69:1302-1313.
    • (2009) Cancer Res , vol.69 , pp. 1302-1313
    • Charafe-Jauffret, E.1
  • 25
    • 60949084535 scopus 로고    scopus 로고
    • Cancer stem cells: A model in the making
    • Marotta LL, Polyak K (2009) Cancer stem cells: A model in the making. Curr Opin Genet Dev 19:44-50.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 44-50
    • Marotta, L.L.1    Polyak, K.2
  • 26
    • 28444454022 scopus 로고    scopus 로고
    • Stem cells in mammary development and carcinogenesis: Implications for prevention and treatment
    • DOI 10.1385/SCR:1:3:207
    • Dontu G, Liu S, Wicha MS (2005) Stem cells in mammary development and carcinogenesis: Implications for prevention and treatment. Stem Cell Rev 1:207-213. (Pubitemid 41737097)
    • (2005) Stem Cell Reviews , vol.1 , Issue.3 , pp. 207-214
    • Dontu, G.1    Liu, S.2    Wicha, M.S.3
  • 27
    • 68349150810 scopus 로고    scopus 로고
    • Mammary development meets cancer genomics
    • Prat A, Perou CM (2009) Mammary development meets cancer genomics. Nat Med 15:842-844.
    • (2009) Nat Med , vol.15 , pp. 842-844
    • Prat, A.1    Perou, C.M.2
  • 28
    • 46749096396 scopus 로고    scopus 로고
    • What can we learn about breast cancer from stem cells?
    • Clarke MF (2008) What can we learn about breast cancer from stem cells? Adv Exp Med Biol 617:17-22.
    • (2008) Adv Exp Med Biol , vol.617 , pp. 17-22
    • Clarke, M.F.1
  • 29
    • 0036900448 scopus 로고    scopus 로고
    • Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ
    • Boecker W, et al. (2002) Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ. J Pathol 198:458-467.
    • (2002) J Pathol , vol.198 , pp. 458-467
    • Boecker, W.1
  • 30
    • 67650032868 scopus 로고    scopus 로고
    • A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
    • Niwa H, Ogawa K, Shimosato D, Adachi K (2009) A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 460:118-122.
    • (2009) Nature , vol.460 , pp. 118-122
    • Niwa, H.1    Ogawa, K.2    Shimosato, D.3    Adachi, K.4
  • 31
    • 70450270857 scopus 로고    scopus 로고
    • Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal
    • Hall J, et al. (2009) Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Cell Stem Cell 5:597-609.
    • (2009) Cell Stem Cell , vol.5 , pp. 597-609
    • Hall, J.1
  • 32
    • 33750566665 scopus 로고    scopus 로고
    • Notch signaling in stem cell systems
    • Chiba S (2006) Notch signaling in stem cell systems. Stem Cells 24:2437-2447.
    • (2006) Stem Cells , vol.24 , pp. 2437-2447
    • Chiba, S.1
  • 33
    • 68549133582 scopus 로고    scopus 로고
    • Wnt signaling and stem cell control
    • Nusse R, et al. (2008) Wnt signaling and stem cell control. Cold Spring Harb Symp Quant Biol 73:59-66.
    • (2008) Cold Spring Harb Symp Quant Biol , vol.73 , pp. 59-66
    • Nusse, R.1
  • 34
    • 33846705750 scopus 로고    scopus 로고
    • Epithelial Stem Cells: Turning over New Leaves
    • DOI 10.1016/j.cell.2007.01.014, PII S0092867407000700
    • Blanpain C, Horsley V, Fuchs E (2007) Epithelial stem cells: Turning over new leaves. Cell 128:445-458. (Pubitemid 46198895)
    • (2007) Cell , vol.128 , Issue.3 , pp. 445-458
    • Blanpain, C.1    Horsley, V.2    Fuchs, E.3
  • 35
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: Tumours, embryos and stem cells
    • Ruiz i Altaba A, Sánchez P, Dahmane N (2002) Gli and hedgehog in cancer: Tumours, embryos and stem cells. Nat Rev Cancer 2:361-372.
    • (2002) Nat Rev Cancer , vol.2 , pp. 361-372
    • Ruiz I Altaba, A.1    Sánchez, P.2    Dahmane, N.3
  • 36
    • 6044269157 scopus 로고    scopus 로고
    • Self-renewal of teratocarcinoma and embryonic stem cells
    • DOI 10.1038/sj.onc.1207930
    • Chambers I, Smith A (2004) Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23:7150-7160. (Pubitemid 39382149)
    • (2004) Oncogene , vol.23 , Issue.43 REV. ISS. 6 , pp. 7150-7160
    • Chambers, I.1    Smith, A.2
  • 37
    • 54949147295 scopus 로고    scopus 로고
    • Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs
    • Ema M, et al. (2008) Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell 3:555-567.
    • (2008) Cell Stem Cell , vol.3 , pp. 555-567
    • Ema, M.1
  • 38
    • 0037012037 scopus 로고    scopus 로고
    • Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit
    • Toouli CD, et al. (2002) Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit. Oncogene 21:128-139.
    • (2002) Oncogene , vol.21 , pp. 128-139
    • Toouli, C.D.1
  • 39
    • 0031468362 scopus 로고    scopus 로고
    • Abrogation of wild-type p53-mediated transactivation is insufficient for mutant p53-induced immortalization of normal human mammary epithelial cells
    • Cao Y, Gao Q, Wazer DE, Band V (1997) Abrogation of wild-type p53-mediated transactivation is insufficient for mutant p53-induced immortalization of normal human mammary epithelial cells. Cancer Res 57:5584-5589.
    • (1997) Cancer Res , vol.57 , pp. 5584-5589
    • Cao, Y.1    Gao, Q.2    Wazer, D.E.3    Band, V.4
  • 40
    • 0035866390 scopus 로고    scopus 로고
    • The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells
    • Nonet GH, et al. (2001) The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells. Cancer Res 61:1250-1254.
    • (2001) Cancer Res , vol.61 , pp. 1250-1254
    • Nonet, G.H.1
  • 41
    • 0037102196 scopus 로고    scopus 로고
    • The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells
    • Dimri GP, et al. (2002) The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Cancer Res 62:4736-4745.
    • (2002) Cancer Res , vol.62 , pp. 4736-4745
    • Dimri, G.P.1
  • 42
    • 0006312841 scopus 로고
    • Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene
    • Stampfer MR, Bartley JC (1985) Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. Proc Natl Acad Sci USA 82:2394-2398.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2394-2398
    • Stampfer, M.R.1    Bartley, J.C.2
  • 43
    • 0028331461 scopus 로고
    • Loss of p53 protein during radiation transformation of primary human mammary epithelial cells
    • Wazer DE, et al. (1994) Loss of p53 protein during radiation transformation of primary human mammary epithelial cells. Mol Cell Biol 14:2468-2478.
    • (1994) Mol Cell Biol , vol.14 , pp. 2468-2478
    • Wazer, D.E.1
  • 44
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • DOI 10.1038/nmeth1015, PII NMETH1015
    • Lee GY, Kenny PA, Lee EH, Bissell MJ (2007) Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 4:359-365. (Pubitemid 46766981)
    • (2007) Nature Methods , vol.4 , Issue.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 45
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • DOI 10.1016/S1046-2023(03)00032-X
    • Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30:256-268. (Pubitemid 36677560)
    • (2003) Methods , vol.30 , Issue.3 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.