Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice

Hepatology

Volumn 52, Issue 3, 2010, Pages 1111-1123

  Chiba, Tetsuhiro ^a,b   Seki, Atsuyoshi ^a   Aoki, Ryutaro ^a   Ichikawa, Hitoshi ^c   Negishi, Masamitsu ^a   Miyagi, Satoru ^a   Oguro, Hideyuki ^a   Saraya, Atsunori ^a   Kamiya, Akihide ^d   Nakauchi, Hiromitsu ^d   Yokosuka, Osamu ^a   Iwama, Atsushi ^a,b  

^a CHIBA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; BMI1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DELTA LIKE PROTEIN; MEMBRANE PROTEIN; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; BMI1 PROTEIN, MOUSE; HIGH MOBILITY GROUP B PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN; SOX17 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOGENICITY; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE LOCUS; GENE REPRESSION; IN VIVO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL EXPANSION; TUMOR SUPPRESSOR GENE; WILD TYPE; ANIMAL; CELL PROLIFERATION; CELL TRANSFORMATION; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; NONOBESE DIABETIC MOUSE; SCID MOUSE;

ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EMBRYONIC STEM CELLS; HMGB PROTEINS; LIVER; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MODELS, ANIMAL; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SOXF TRANSCRIPTION FACTORS; POLYCOMB REPRESSIVE COMPLEX 1;

EID: 77956637856     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23793     Document Type: Article

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