-
1
-
-
33745481241
-
Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation
-
Akiyoshi T., Nakamura M., Koga K., Nakashima H., Yao T., Tsuneyoshi M., Tanaka M., Katano M. Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation. Gut 2006, 55:991-999.
-
(2006)
Gut
, vol.55
, pp. 991-999
-
-
Akiyoshi, T.1
Nakamura, M.2
Koga, K.3
Nakashima, H.4
Yao, T.5
Tsuneyoshi, M.6
Tanaka, M.7
Katano, M.8
-
2
-
-
67650951418
-
Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling
-
Arimura S., Matsunaga A., Kitamura T., Aoki K., Aoki M., Taketo M.M. Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling. Gastroenterology 2009, 137:629-638.
-
(2009)
Gastroenterology
, vol.137
, pp. 629-638
-
-
Arimura, S.1
Matsunaga, A.2
Kitamura, T.3
Aoki, K.4
Aoki, M.5
Taketo, M.M.6
-
3
-
-
0036406843
-
Hedgehog signaling and human disease
-
Bale A.E. Hedgehog signaling and human disease. Annu. Rev. Genomics Hum. Genet. 2002, 3:47-65.
-
(2002)
Annu. Rev. Genomics Hum. Genet.
, vol.3
, pp. 47-65
-
-
Bale, A.E.1
-
4
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman D.M., Karhadkar S.S., Maitra A., Montes De Oca R., Gerstenblith M.R., Briggs K., Parker A.R., Shimada Y., Eshleman J.R., Watkins D.N., Beachy P.A. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003, 425:846-851.
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
5
-
-
34248138532
-
Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas
-
Bian Y.H., Huang S.H., Yang L., Ma X.L., Xie J.W., Zhang H.W. Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas. World J. Gastroenterol. 2007, 13:1659-1665.
-
(2007)
World J. Gastroenterol.
, vol.13
, pp. 1659-1665
-
-
Bian, Y.H.1
Huang, S.H.2
Yang, L.3
Ma, X.L.4
Xie, J.W.5
Zhang, H.W.6
-
6
-
-
51049091878
-
Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age
-
Brown L.M., Devesa S.S., Chow W.H. Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age. J. Natl. Cancer Inst. 2008, 100:1184-1187.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1184-1187
-
-
Brown, L.M.1
Devesa, S.S.2
Chow, W.H.3
-
7
-
-
0027939318
-
Products, genetic linkage and limb patterning activity of a murine hedgehog gene
-
Chang D.T., Lopez A., von Kessler D.P., Chiang C., Simandl B.K., Zhao R., Seldin M.F., Fallon J.F., Beachy P.A. Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 1994, 120:3339-3353.
-
(1994)
Development
, vol.120
, pp. 3339-3353
-
-
Chang, D.T.1
Lopez, A.2
von Kessler, D.P.3
Chiang, C.4
Simandl, B.K.5
Zhao, R.6
Seldin, M.F.7
Fallon, J.F.8
Beachy, P.A.9
-
8
-
-
36248953744
-
Hedgehog signaling pathway is inactive in colorectal cancer cell lines
-
Chatel G., Ganeff C., Boussif N., Delacroix L., Briquet A., Nolens G., Winkler R. Hedgehog signaling pathway is inactive in colorectal cancer cell lines. Int. J. Cancer 2007, 121:2622-2627.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 2622-2627
-
-
Chatel, G.1
Ganeff, C.2
Boussif, N.3
Delacroix, L.4
Briquet, A.5
Nolens, G.6
Winkler, R.7
-
9
-
-
11144256194
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
-
Chen W., Ren X.R., Nelson C.D., Barak L.S., Chen J.K., Beachy P.A., de Sauvage F., Lefkowitz R.J. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science 2004, 306:2257-2260.
-
(2004)
Science
, vol.306
, pp. 2257-2260
-
-
Chen, W.1
Ren, X.R.2
Nelson, C.D.3
Barak, L.S.4
Chen, J.K.5
Beachy, P.A.6
de Sauvage, F.7
Lefkowitz, R.J.8
-
10
-
-
0347995025
-
Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions
-
Dimmler A., Brabletz T., Hlubek F., Hafner M., Rau T., Kirchner T., Faller G. Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions. Lab. Invest. 2003, 83:1829-1837.
-
(2003)
Lab. Invest.
, vol.83
, pp. 1829-1837
-
-
Dimmler, A.1
Brabletz, T.2
Hlubek, F.3
Hafner, M.4
Rau, T.5
Kirchner, T.6
Faller, G.7
-
11
-
-
70349237014
-
Following the hedgehog to new cancer therapies
-
Dlugosz A.A., Talpaz M. Following the hedgehog to new cancer therapies. N. Engl. J. Med. 2009, 361:1202-1205.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1202-1205
-
-
Dlugosz, A.A.1
Talpaz, M.2
-
12
-
-
33646407865
-
Sonic Hedgehog-dependent proliferation in a series of patients with colorectal cancer
-
Douard R., Moutereau S., Pernet P., Chimingqi M., Allory Y., Manivet P., Conti M., Vaubourdolle M., Cugnenc P.H., Loric S. Sonic Hedgehog-dependent proliferation in a series of patients with colorectal cancer. Surgery 2006, 139:665-670.
-
(2006)
Surgery
, vol.139
, pp. 665-670
-
-
Douard, R.1
Moutereau, S.2
Pernet, P.3
Chimingqi, M.4
Allory, Y.5
Manivet, P.6
Conti, M.7
Vaubourdolle, M.8
Cugnenc, P.H.9
Loric, S.10
-
13
-
-
0027756145
-
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
-
Echelard Y., Epstein D.J., St-Jacques B., Shen L., Mohler J., McMahon J.A., McMahon A.P. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993, 75:1417-1430.
-
(1993)
Cell
, vol.75
, pp. 1417-1430
-
-
Echelard, Y.1
Epstein, D.J.2
St-Jacques, B.3
Shen, L.4
Mohler, J.5
McMahon, J.A.6
McMahon, A.P.7
-
14
-
-
58849108264
-
Sonic hedgehog in gastric physiology and neoplastic transformation: Friend or foe?
-
El-Zaatari M., Saqui-Salces M., Waghray M., Todisco A., Merchant J.L. Sonic hedgehog in gastric physiology and neoplastic transformation: Friend or foe?. Curr. Opin. Endocrinol. Diabetes Obes. 2009, 16:60-65.
-
(2009)
Curr. Opin. Endocrinol. Diabetes Obes.
, vol.16
, pp. 60-65
-
-
El-Zaatari, M.1
Saqui-Salces, M.2
Waghray, M.3
Todisco, A.4
Merchant, J.L.5
-
15
-
-
78649307378
-
Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion
-
2061.e2-2071.e2
-
El-Zaatari M., Zavros Y., Tessier A., Waghray M., Lentz S., Gumucio D., Todisco A., Merchant J.L. Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion. Gastroenterology 2010, 139. 2061.e2-2071.e2.
-
(2010)
Gastroenterology
, vol.139
-
-
El-Zaatari, M.1
Zavros, Y.2
Tessier, A.3
Waghray, M.4
Lentz, S.5
Gumucio, D.6
Todisco, A.7
Merchant, J.L.8
-
16
-
-
13144257735
-
Immunological and morphogenic basis of gastric mucosa atrophy and metaplasia
-
Faller G., Kirchner T. Immunological and morphogenic basis of gastric mucosa atrophy and metaplasia. Virchows Arch. 2005, 446:1-9.
-
(2005)
Virchows Arch.
, vol.446
, pp. 1-9
-
-
Faller, G.1
Kirchner, T.2
-
17
-
-
73649084812
-
Indian hedgehog, a neglected member of hedgehog pathway, may offer a novel avenue for colorectal cancer therapy
-
Fu X., Yang X., Zhao L. Indian hedgehog, a neglected member of hedgehog pathway, may offer a novel avenue for colorectal cancer therapy. Cancer Biother. Radiopharm. 2009, 24:733-735.
-
(2009)
Cancer Biother. Radiopharm.
, vol.24
, pp. 733-735
-
-
Fu, X.1
Yang, X.2
Zhao, L.3
-
18
-
-
77949657774
-
Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters
-
Fu X., Deng H., Zhao L., Li J., Zhou Y., Zhang Y. Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters. Mol. Cell. Biochem. 2010, 337:185-192.
-
(2010)
Mol. Cell. Biochem.
, vol.337
, pp. 185-192
-
-
Fu, X.1
Deng, H.2
Zhao, L.3
Li, J.4
Zhou, Y.5
Zhang, Y.6
-
19
-
-
33745745896
-
Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer
-
Fukaya M., Isohata N., Ohta H., Aoyagi K., Ochiya T., Saeki N., Yanagihara K., Nakanishi Y., Taniguchi H., Sakamoto H., Shimoda T., Nimura Y., et al. Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer. Gastroenterology 2006, 131:14-29.
-
(2006)
Gastroenterology
, vol.131
, pp. 14-29
-
-
Fukaya, M.1
Isohata, N.2
Ohta, H.3
Aoyagi, K.4
Ochiya, T.5
Saeki, N.6
Yanagihara, K.7
Nakanishi, Y.8
Taniguchi, H.9
Sakamoto, H.10
Shimoda, T.11
Nimura, Y.12
-
20
-
-
68949147586
-
Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2
-
Han M.E., Lee Y.S., Baek S.Y., Kim B.S., Kim J.B., Oh S.O. Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2. Int. J. Mol. Sci. 2009, 10:3033-3043.
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 3033-3043
-
-
Han, M.E.1
Lee, Y.S.2
Baek, S.Y.3
Kim, B.S.4
Kim, J.B.5
Oh, S.O.6
-
21
-
-
42549103845
-
Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa
-
Haveri H., Westerholm-Ormio M., Lindfors K., Maki M., Savilahti E., Andersson L.C., Heikinheimo M. Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa. BMC Gastroenterol. 2008, 8:9.
-
(2008)
BMC Gastroenterol.
, vol.8
, pp. 9
-
-
Haveri, H.1
Westerholm-Ormio, M.2
Lindfors, K.3
Maki, M.4
Savilahti, E.5
Andersson, L.C.6
Heikinheimo, M.7
-
22
-
-
33646708988
-
Decrease in the esophageal cancer incidence rate in mountainous but not level parts of Cixian County, China, over 29 years
-
He Y.T., Hou J., Chen Z.F., Qiao C.Y., Song G.H., Meng F.S., Jin H.X., Chen C. Decrease in the esophageal cancer incidence rate in mountainous but not level parts of Cixian County, China, over 29 years. Asian Pac. J. Cancer Prev. 2005, 6:510-514.
-
(2005)
Asian Pac. J. Cancer Prev.
, vol.6
, pp. 510-514
-
-
He, Y.T.1
Hou, J.2
Chen, Z.F.3
Qiao, C.Y.4
Song, G.H.5
Meng, F.S.6
Jin, H.X.7
Chen, C.8
-
23
-
-
33845967146
-
Suppressing Wnt signaling by the hedgehog pathway through sFRP-1
-
He J., Sheng T., Stelter A.A., Li C., Zhang X., Sinha M., Luxon B.A., Xie J. Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. J. Biol. Chem. 2006, 281:35598-35602.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 35598-35602
-
-
He, J.1
Sheng, T.2
Stelter, A.A.3
Li, C.4
Zhang, X.5
Sinha, M.6
Luxon, B.A.7
Xie, J.8
-
24
-
-
33750200389
-
Orchestrating ontogenesis: Variations on a theme by sonic hedgehog
-
Ingham P.W., Placzek M. Orchestrating ontogenesis: Variations on a theme by sonic hedgehog. Nat. Rev. Genet. 2006, 7:841-850.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 841-850
-
-
Ingham, P.W.1
Placzek, M.2
-
25
-
-
67650070517
-
Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus
-
Isohata N., Aoyagi K., Mabuchi T., Daiko H., Fukaya M., Ohta H., Ogawa K., Yoshida T., Sasaki H. Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus. Int. J. Cancer 2009, 125:1212-1221.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 1212-1221
-
-
Isohata, N.1
Aoyagi, K.2
Mabuchi, T.3
Daiko, H.4
Fukaya, M.5
Ohta, H.6
Ogawa, K.7
Yoshida, T.8
Sasaki, H.9
-
26
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., Thun M.J. Cancer statistics, 2008. CA Cancer J. Clin. 2008, 58:71-96.
-
(2008)
CA Cancer J. Clin.
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
27
-
-
76949106078
-
Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer
-
Kameda C., Nakamura M., Tanaka H., Yamasaki A., Kubo M., Tanaka M., Onishi H., Katano M. Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer. Br. J. Cancer 2010, 102:738-747.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 738-747
-
-
Kameda, C.1
Nakamura, M.2
Tanaka, H.3
Yamasaki, A.4
Kubo, M.5
Tanaka, M.6
Onishi, H.7
Katano, M.8
-
28
-
-
67349128594
-
The role of hedgehog signaling during gastric regeneration
-
Kang D.H., Han M.E., Song M.H., Lee Y.S., Kim E.H., Kim H.J., Kim G.H., Kim D.H., Yoon S., Baek S.Y., Kim B.S., Kim J.B., et al. The role of hedgehog signaling during gastric regeneration. J. Gastroenterol. 2009, 44:372-379.
-
(2009)
J. Gastroenterol.
, vol.44
, pp. 372-379
-
-
Kang, D.H.1
Han, M.E.2
Song, M.H.3
Lee, Y.S.4
Kim, E.H.5
Kim, H.J.6
Kim, G.H.7
Kim, D.H.8
Yoon, S.9
Baek, S.Y.10
Kim, B.S.11
Kim, J.B.12
-
29
-
-
28444434457
-
Gli3 null mice display glandular overgrowth of the developing stomach
-
Kim J.H., Huang Z., Mo R. Gli3 null mice display glandular overgrowth of the developing stomach. Dev. Dyn. 2005, 234:984-991.
-
(2005)
Dev. Dyn.
, vol.234
, pp. 984-991
-
-
Kim, J.H.1
Huang, Z.2
Mo, R.3
-
30
-
-
77951749929
-
Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells
-
Kim J.H., Choi Y.J., Lee S.H., Shin H.S., Lee I.O., Kim Y.J., Kim H., Yang W.I., Lee Y.C. Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells. Oncol. Rep. 2010, 23:1523-1528.
-
(2010)
Oncol. Rep.
, vol.23
, pp. 1523-1528
-
-
Kim, J.H.1
Choi, Y.J.2
Lee, S.H.3
Shin, H.S.4
Lee, I.O.5
Kim, Y.J.6
Kim, H.7
Yang, W.I.8
Lee, Y.C.9
-
31
-
-
75649088945
-
Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: Relevance of crosstalk mechanisms
-
Kim J.H., Shin H.S., Lee S.H., Lee I., Lee Y.S., Park J.C., Kim Y.J., Chung J.B., Lee Y.C. Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: Relevance of crosstalk mechanisms. Cancer Sci. 2010, 101:328-335.
-
(2010)
Cancer Sci.
, vol.101
, pp. 328-335
-
-
Kim, J.H.1
Shin, H.S.2
Lee, S.H.3
Lee, I.4
Lee, Y.S.5
Park, J.C.6
Kim, Y.J.7
Chung, J.B.8
Lee, Y.C.9
-
32
-
-
0025156778
-
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome
-
Kinzler K.W., Vogelstein B. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome. Mol. Cell. Biol. 1990, 10:634-642.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 634-642
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
33
-
-
67650979371
-
Paracrine Hedgehog signaling in stomach and intestine: New roles for hedgehog in gastrointestinal patterning
-
Kolterud A., Grosse A.S., Zacharias W.J., Walton K.D., Kretovich K.E., Madison B.B., Waghray M., Ferris J.E., Hu C., Merchant J.L., Dlugosz A.A., Kottmann A.H., et al. Paracrine Hedgehog signaling in stomach and intestine: New roles for hedgehog in gastrointestinal patterning. Gastroenterology 2009, 137:618-628.
-
(2009)
Gastroenterology
, vol.137
, pp. 618-628
-
-
Kolterud, A.1
Grosse, A.S.2
Zacharias, W.J.3
Walton, K.D.4
Kretovich, K.E.5
Madison, B.B.6
Waghray, M.7
Ferris, J.E.8
Hu, C.9
Merchant, J.L.10
Dlugosz, A.A.11
Kottmann, A.H.12
-
34
-
-
0027749249
-
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos
-
Krauss S., Concordet J.P., Ingham P.W. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 1993, 75:1431-1444.
-
(1993)
Cell
, vol.75
, pp. 1431-1444
-
-
Krauss, S.1
Concordet, J.P.2
Ingham, P.W.3
-
35
-
-
34548583593
-
Sonic hedgehog expression in gastric cancer and gastric adenoma
-
Lee S.Y., Han H.S., Lee K.Y., Hwang T.S., Kim J.H., Sung I.K., Park H.S., Jin C.J., Choi K.W. Sonic hedgehog expression in gastric cancer and gastric adenoma. Oncol. Rep. 2007, 17:1051-1055.
-
(2007)
Oncol. Rep.
, vol.17
, pp. 1051-1055
-
-
Lee, S.Y.1
Han, H.S.2
Lee, K.Y.3
Hwang, T.S.4
Kim, J.H.5
Sung, I.K.6
Park, H.S.7
Jin, C.J.8
Choi, K.W.9
-
36
-
-
72049104191
-
Late reactivation of sonic hedgehog by Helicobacter pylori results in population of gastric epithelial cells that are resistant to apoptosis: Implication for gastric carcinogenesis
-
Lee K.M., Lee J.S., Jung H.S., Park D.K., Park H.S., Hahm K.B. Late reactivation of sonic hedgehog by Helicobacter pylori results in population of gastric epithelial cells that are resistant to apoptosis: Implication for gastric carcinogenesis. Cancer Lett. 2010, 287:44-53.
-
(2010)
Cancer Lett.
, vol.287
, pp. 44-53
-
-
Lee, K.M.1
Lee, J.S.2
Jung, H.S.3
Park, D.K.4
Park, H.S.5
Hahm, K.B.6
-
37
-
-
79954486712
-
Clinical implications of hedgehog signaling pathway inhibitors
-
Liu H., Gu D., Xie J. Clinical implications of hedgehog signaling pathway inhibitors. Chin. J. Cancer 2011, 30:13-26.
-
(2011)
Chin. J. Cancer
, vol.30
, pp. 13-26
-
-
Liu, H.1
Gu, D.2
Xie, J.3
-
38
-
-
27144541492
-
Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
-
Ma X., Chen K., Huang S., Zhang X., Adegboyega P.A., Evers B.M., Zhang H., Xie J. Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas. Carcinogenesis 2005, 26:1698-1705.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1698-1705
-
-
Ma, X.1
Chen, K.2
Huang, S.3
Zhang, X.4
Adegboyega, P.A.5
Evers, B.M.6
Zhang, H.7
Xie, J.8
-
39
-
-
27944470037
-
Hedgehog signaling is activated in subsets of esophageal cancers
-
Ma X., Sheng T., Zhang Y., Zhang X., He J., Huang S., Chen K., Sultz J., Adegboyega P.A., Zhang H., Xie J. Hedgehog signaling is activated in subsets of esophageal cancers. Int. J. Cancer 2006, 118:139-148.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 139-148
-
-
Ma, X.1
Sheng, T.2
Zhang, Y.3
Zhang, X.4
He, J.5
Huang, S.6
Chen, K.7
Sultz, J.8
Adegboyega, P.A.9
Zhang, H.10
Xie, J.11
-
40
-
-
65549099669
-
FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine
-
Madison B.B., McKenna L.B., Dolson D., Epstein D.J., Kaestner K.H. FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J. Biol. Chem. 2009, 284:5936-5944.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5936-5944
-
-
Madison, B.B.1
McKenna, L.B.2
Dolson, D.3
Epstein, D.J.4
Kaestner, K.H.5
-
41
-
-
79551540949
-
Hedgehog signaling drives cellular survival in human colon carcinoma cells
-
Mazumdar T., Devecchio J., Ting S., Jones J., Agyeman A., Houghton J.A. Hedgehog signaling drives cellular survival in human colon carcinoma cells. Cancer Res. 2010, 71:1092-1102.
-
(2010)
Cancer Res.
, vol.71
, pp. 1092-1102
-
-
Mazumdar, T.1
Devecchio, J.2
Ting, S.3
Jones, J.4
Agyeman, A.5
Houghton, J.A.6
-
42
-
-
0035955642
-
Suppressor of fused negatively regulates beta-catenin signaling
-
Meng X., Poon R., Zhang X., Cheah A., Ding Q., Hui C.C., Alman B. Suppressor of fused negatively regulates beta-catenin signaling. J. Biol. Chem. 2001, 276:40113-40119.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40113-40119
-
-
Meng, X.1
Poon, R.2
Zhang, X.3
Cheah, A.4
Ding, Q.5
Hui, C.C.6
Alman, B.7
-
43
-
-
35348941302
-
Reduced Shh expression in TFF2-overexpressing lesions of the gastric fundus under hypochlorhydric conditions
-
Minegishi Y., Suzuki H., Arakawa M., Fukushima Y., Masaoka T., Ishikawa T., Wright N.A., Hibi T. Reduced Shh expression in TFF2-overexpressing lesions of the gastric fundus under hypochlorhydric conditions. J. Pathol. 2007, 213:161-169.
-
(2007)
J. Pathol.
, vol.213
, pp. 161-169
-
-
Minegishi, Y.1
Suzuki, H.2
Arakawa, M.3
Fukushima, Y.4
Masaoka, T.5
Ishikawa, T.6
Wright, N.A.7
Hibi, T.8
-
44
-
-
33846060232
-
Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma
-
Mori Y., Okumura T., Tsunoda S., Sakai Y., Shimada Y. Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma. Oncology 2006, 70:378-389.
-
(2006)
Oncology
, vol.70
, pp. 378-389
-
-
Mori, Y.1
Okumura, T.2
Tsunoda, S.3
Sakai, Y.4
Shimada, Y.5
-
45
-
-
34250220294
-
Helicobacter pylori eradication restored sonic hedgehog expression in the stomach
-
Nishizawa T., Suzuki H., Masaoka T., Minegishi Y., Iwasahi E., Hibi T. Helicobacter pylori eradication restored sonic hedgehog expression in the stomach. Hepatogastroenterology 2007, 54:697-700.
-
(2007)
Hepatogastroenterology
, vol.54
, pp. 697-700
-
-
Nishizawa, T.1
Suzuki, H.2
Masaoka, T.3
Minegishi, Y.4
Iwasahi, E.5
Hibi, T.6
-
46
-
-
62349119037
-
Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils
-
Nishizawa T., Suzuki H., Nakagawa I., Minegishi Y., Masaoka T., Iwasaki E., Hibi T. Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils. Digestion 2009, 79:99-108.
-
(2009)
Digestion
, vol.79
, pp. 99-108
-
-
Nishizawa, T.1
Suzuki, H.2
Nakagawa, I.3
Minegishi, Y.4
Masaoka, T.5
Iwasaki, E.6
Hibi, T.7
-
47
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
Nusslein-Volhard C., Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980, 287:795-801.
-
(1980)
Nature
, vol.287
, pp. 795-801
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
-
48
-
-
28244447471
-
P53-independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells
-
Ohta M., Tateishi K., Kanai F., Watabe H., Kondo S., Guleng B., Tanaka Y., Asaoka Y., Jazag A., Imamura J., Ijichi H., Ikenoue T., et al. p53-independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells. Cancer Res. 2005, 65:10822-10829.
-
(2005)
Cancer Res.
, vol.65
, pp. 10822-10829
-
-
Ohta, M.1
Tateishi, K.2
Kanai, F.3
Watabe, H.4
Kondo, S.5
Guleng, B.6
Tanaka, Y.7
Asaoka, Y.8
Jazag, A.9
Imamura, J.10
Ijichi, H.11
Ikenoue, T.12
-
49
-
-
58749087502
-
Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers
-
Ohta H., Aoyagi K., Fukaya M., Danjoh I., Ohta A., Isohata N., Saeki N., Taniguchi H., Sakamoto H., Shimoda T., Tani T., Yoshida T., et al. Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers. Br. J. Cancer 2009, 100:389-398.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 389-398
-
-
Ohta, H.1
Aoyagi, K.2
Fukaya, M.3
Danjoh, I.4
Ohta, A.5
Isohata, N.6
Saeki, N.7
Taniguchi, H.8
Sakamoto, H.9
Shimoda, T.10
Tani, T.11
Yoshida, T.12
-
50
-
-
4143097168
-
Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia
-
Oniscu A., James R.M., Morris R.G., Bader S., Malcomson R.D., Harrison D.J. Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia. J. Pathol. 2004, 203:909-917.
-
(2004)
J. Pathol.
, vol.203
, pp. 909-917
-
-
Oniscu, A.1
James, R.M.2
Morris, R.G.3
Bader, S.4
Malcomson, R.D.5
Harrison, D.J.6
-
51
-
-
33646102912
-
Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration
-
Osawa H., Ohnishi H., Takano K., Noguti T., Mashima H., Hoshino H., Kita H., Sato K., Matsui H., Sugano K. Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration. Biochem. Biophys. Res. Commun. 2006, 344:680-687.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 680-687
-
-
Osawa, H.1
Ohnishi, H.2
Takano, K.3
Noguti, T.4
Mashima, H.5
Hoshino, H.6
Kita, H.7
Sato, K.8
Matsui, H.9
Sugano, K.10
-
52
-
-
2942533929
-
Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment
-
Qualtrough D., Buda A., Gaffield W., Williams A.C., Paraskeva C. Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment. Int. J. Cancer 2004, 110:831-837.
-
(2004)
Int. J. Cancer
, vol.110
, pp. 831-837
-
-
Qualtrough, D.1
Buda, A.2
Gaffield, W.3
Williams, A.C.4
Paraskeva, C.5
-
53
-
-
0027760995
-
Sonic hedgehog mediates the polarizing activity of the ZPA
-
Riddle R.D., Johnson R.L., Laufer E., Tabin C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 1993, 75:1401-1416.
-
(1993)
Cell
, vol.75
, pp. 1401-1416
-
-
Riddle, R.D.1
Johnson, R.L.2
Laufer, E.3
Tabin, C.4
-
54
-
-
77956284378
-
Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis
-
Rizvi S., Demars C.J., Comba A., Gainullin V.G., Rizvi Z., Almada L.L., Wang K., Lomberk G., Fernandez-Zapico M.E., Buttar N.S. Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis. Cancer Res. 2010, 70:6787-6796.
-
(2010)
Cancer Res.
, vol.70
, pp. 6787-6796
-
-
Rizvi, S.1
Demars, C.J.2
Comba, A.3
Gainullin, V.G.4
Rizvi, Z.5
Almada, L.L.6
Wang, K.7
Lomberk, G.8
Fernandez-Zapico, M.E.9
Buttar, N.S.10
-
55
-
-
23444440157
-
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
-
Roelink H., Augsburger A., Heemskerk J., Korzh V., Norlin S., Ruiz i Altaba A., Tanabe Y., Placzek M., Edlund T., Jessell T.M., et al. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 1994, 76:761-775.
-
(1994)
Cell
, vol.76
, pp. 761-775
-
-
Roelink, H.1
Augsburger, A.2
Heemskerk, J.3
Korzh, V.4
Norlin, S.5
Ruiz i Altaba, A.6
Tanabe, Y.7
Placzek, M.8
Edlund, T.9
Jessell, T.M.10
-
56
-
-
0030891148
-
A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro
-
Sasaki H., Hui C., Nakafuku M., Kondoh H. A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 1997, 124:1313-1322.
-
(1997)
Development
, vol.124
, pp. 1313-1322
-
-
Sasaki, H.1
Hui, C.2
Nakafuku, M.3
Kondoh, H.4
-
57
-
-
68849105590
-
Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer
-
Seto M., Ohta M., Asaoka Y., Ikenoue T., Tada M., Miyabayashi K., Mohri D., Tanaka Y., Ijichi H., Tateishi K., Kanai F., Kawabe T., et al. Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer. Mol. Carcinog. 2009, 48:703-712.
-
(2009)
Mol. Carcinog.
, vol.48
, pp. 703-712
-
-
Seto, M.1
Ohta, M.2
Asaoka, Y.3
Ikenoue, T.4
Tada, M.5
Miyabayashi, K.6
Mohri, D.7
Tanaka, Y.8
Ijichi, H.9
Tateishi, K.10
Kanai, F.11
Kawabe, T.12
-
58
-
-
33748469128
-
Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells
-
Shafaee Z., Schmidt H., Du W., Posner M., Weichselbaum R. Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells. Cancer Chemother. Pharmacol. 2006, 58:765-770.
-
(2006)
Cancer Chemother. Pharmacol.
, vol.58
, pp. 765-770
-
-
Shafaee, Z.1
Schmidt, H.2
Du, W.3
Posner, M.4
Weichselbaum, R.5
-
59
-
-
70449371472
-
Genentech obtains proof of concept for hedgehog inhibition
-
Sheridan C. Genentech obtains proof of concept for hedgehog inhibition. Nat. Biotechnol. 2009, 27:968-969.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 968-969
-
-
Sheridan, C.1
-
60
-
-
16844362860
-
Evidence that loss of sonic hedgehog is an indicator of Helicobacter pylori-induced atrophic gastritis progressing to gastric cancer
-
Shiotani A., Iishi H., Uedo N., Ishiguro S., Tatsuta M., Nakae Y., Kumamoto M., Merchant J.L. Evidence that loss of sonic hedgehog is an indicator of Helicobacter pylori-induced atrophic gastritis progressing to gastric cancer. Am. J. Gastroenterol. 2005, 100:581-587.
-
(2005)
Am. J. Gastroenterol.
, vol.100
, pp. 581-587
-
-
Shiotani, A.1
Iishi, H.2
Uedo, N.3
Ishiguro, S.4
Tatsuta, M.5
Nakae, Y.6
Kumamoto, M.7
Merchant, J.L.8
-
61
-
-
34548069382
-
Re-expression of sonic hedgehog and reduction of CDX2 after Helicobacter pylori eradication prior to incomplete intestinal metaplasia
-
Shiotani A., Uedo N., Iishi H., Tatsuta M., Ishiguro S., Nakae Y., Kamada T., Haruma K., Merchant J.L. Re-expression of sonic hedgehog and reduction of CDX2 after Helicobacter pylori eradication prior to incomplete intestinal metaplasia. Int. J. Cancer 2007, 121:1182-1189.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1182-1189
-
-
Shiotani, A.1
Uedo, N.2
Iishi, H.3
Tatsuta, M.4
Ishiguro, S.5
Nakae, Y.6
Kamada, T.7
Haruma, K.8
Merchant, J.L.9
-
62
-
-
33751285537
-
Hedgehog: An attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response
-
Sims-Mourtada J., Izzo J.G., Apisarnthanarax S., Wu T.T., Malhotra U., Luthra R., Liao Z., Komaki R., van der Kogel A., Ajani J., Chao K.S. Hedgehog: An attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response. Clin. Cancer Res. 2006, 12:6565-6572.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 6565-6572
-
-
Sims-Mourtada, J.1
Izzo, J.G.2
Apisarnthanarax, S.3
Wu, T.T.4
Malhotra, U.5
Luthra, R.6
Liao, Z.7
Komaki, R.8
van der Kogel, A.9
Ajani, J.10
Chao, K.S.11
-
63
-
-
2642575932
-
Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: Similarity to human Barrett's esophagus
-
Su Y., Chen X., Klein M., Fang M., Wang S., Yang C.S., Goyal R.K. Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: Similarity to human Barrett's esophagus. Lab. Invest. 2004, 84:753-765.
-
(2004)
Lab. Invest.
, vol.84
, pp. 753-765
-
-
Su, Y.1
Chen, X.2
Klein, M.3
Fang, M.4
Wang, S.5
Yang, C.S.6
Goyal, R.K.7
-
64
-
-
33744974729
-
Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model
-
Sui G., Bonde P., Dhara S., Broor A., Wang J., Marti G., Feldmann G., Duncan M., Montgomery E., Maitra A., Harmon J.W. Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model. J. Surg. Res. 2006, 134:1-9.
-
(2006)
J. Surg. Res.
, vol.134
, pp. 1-9
-
-
Sui, G.1
Bonde, P.2
Dhara, S.3
Broor, A.4
Wang, J.5
Marti, G.6
Feldmann, G.7
Duncan, M.8
Montgomery, E.9
Maitra, A.10
Harmon, J.W.11
-
65
-
-
18544377697
-
COUP-TFII is essential for radial and anteroposterior patterning of the stomach
-
Takamoto N., You L.R., Moses K., Chiang C., Zimmer W.E., Schwartz R.J., DeMayo F.J., Tsai M.J., Tsai S.Y. COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development 2005, 132:2179-2189.
-
(2005)
Development
, vol.132
, pp. 2179-2189
-
-
Takamoto, N.1
You, L.R.2
Moses, K.3
Chiang, C.4
Zimmer, W.E.5
Schwartz, R.J.6
DeMayo, F.J.7
Tsai, M.J.8
Tsai, S.Y.9
-
66
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer S.P., di Magliano M.P., Heiser P.W., Nielsen C.M., Roberts D.J., Lauwers G.Y., Qi Y.P., Gysin S., Fernandez-del Castillo C., Yajnik V., Antoniu B., McMahon M., et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003, 425:851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
-
67
-
-
35648977027
-
Hedgehog signaling in development and homeostasis of the gastrointestinal tract
-
van den Brink G.R. Hedgehog signaling in development and homeostasis of the gastrointestinal tract. Physiol. Rev. 2007, 87:1343-1375.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 1343-1375
-
-
van den Brink, G.R.1
-
68
-
-
10744233571
-
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
-
van den Brink G.R., Bleuming S.A., Hardwick J.C., Schepman B.L., Offerhaus G.J., Keller J.J., Nielsen C., Gaffield W., van Deventer S.J., Roberts D.J., Peppelenbosch M.P. Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. Nat. Genet. 2004, 36:277-282.
-
(2004)
Nat. Genet.
, vol.36
, pp. 277-282
-
-
van den Brink, G.R.1
Bleuming, S.A.2
Hardwick, J.C.3
Schepman, B.L.4
Offerhaus, G.J.5
Keller, J.J.6
Nielsen, C.7
Gaffield, W.8
van Deventer, S.J.9
Roberts, D.J.10
Peppelenbosch, M.P.11
-
69
-
-
73649145223
-
Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
-
Varnat F., Duquet A., Malerba M., Zbinden M., Mas C., Gervaz P., Ruiz i Altaba A. Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. EMBO Mol. Med. 2009, 1:338-351.
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 338-351
-
-
Varnat, F.1
Duquet, A.2
Malerba, M.3
Zbinden, M.4
Mas, C.5
Gervaz, P.6
Ruiz i Altaba, A.7
-
70
-
-
78649307157
-
Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas
-
Varnat F., Siegl-Cachedenier I., Malerba M., Gervaz P., Ruiz i Altaba A. Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas. EMBO Mol. Med. 2010, 2:440-457.
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 440-457
-
-
Varnat, F.1
Siegl-Cachedenier, I.2
Malerba, M.3
Gervaz, P.4
Ruiz i Altaba, A.5
-
71
-
-
70349238733
-
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff D.D., LoRusso P.M., Rudin C.M., Reddy J.C., Yauch R.L., Tibes R., Weiss G.J., Borad M.J., Hann C.L., Brahmer J.R., Mackey H.M., Lum B.L., et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N. Engl. J. Med. 2009, 361:1164-1172.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1164-1172
-
-
Von Hoff, D.D.1
LoRusso, P.M.2
Rudin, C.M.3
Reddy, J.C.4
Yauch, R.L.5
Tibes, R.6
Weiss, G.J.7
Borad, M.J.8
Hann, C.L.9
Brahmer, J.R.10
Mackey, H.M.11
Lum, B.L.12
-
72
-
-
75149191890
-
Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog
-
572e1-e2
-
Waghray M., Zavros Y., Saqui-Salces M., El-Zaatari M., Alamelumangapuram C.B., Todisco A., Eaton K.A., Merchant J.L. Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog. Gastroenterology 2010, 138:562-572. 572e1-e2.
-
(2010)
Gastroenterology
, vol.138
, pp. 562-572
-
-
Waghray, M.1
Zavros, Y.2
Saqui-Salces, M.3
El-Zaatari, M.4
Alamelumangapuram, C.B.5
Todisco, A.6
Eaton, K.A.7
Merchant, J.L.8
-
73
-
-
33646137574
-
Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions
-
Wang L.H., Choi Y.L., Hua X.Y., Shin Y.K., Song Y.J., Youn S.J., Yun H.Y., Park S.M., Kim W.J., Kim H.J., Choi J.S., Kim S.H. Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions. Mod. Pathol. 2006, 19:675-683.
-
(2006)
Mod. Pathol.
, vol.19
, pp. 675-683
-
-
Wang, L.H.1
Choi, Y.L.2
Hua, X.Y.3
Shin, Y.K.4
Song, Y.J.5
Youn, S.J.6
Yun, H.Y.7
Park, S.M.8
Kim, W.J.9
Kim, H.J.10
Choi, J.S.11
Kim, S.H.12
-
74
-
-
77951684109
-
Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia
-
Wang D.H., Clemons N.J., Miyashita T., Dupuy A.J., Zhang W., Szczepny A., Corcoran-Schwartz I.M., Wilburn D.L., Montgomery E.A., Wang J.S., Jenkins N.A., Copeland N.A., et al. Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia. Gastroenterology 2010, 138:1810-1822.
-
(2010)
Gastroenterology
, vol.138
, pp. 1810-1822
-
-
Wang, D.H.1
Clemons, N.J.2
Miyashita, T.3
Dupuy, A.J.4
Zhang, W.5
Szczepny, A.6
Corcoran-Schwartz, I.M.7
Wilburn, D.L.8
Montgomery, E.A.9
Wang, J.S.10
Jenkins, N.A.11
Copeland, N.A.12
-
75
-
-
79961123374
-
Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer
-
Wei L., Xu Z. Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer. Int. J. Cancer 2010, 129:275-284.
-
(2010)
Int. J. Cancer
, vol.129
, pp. 275-284
-
-
Wei, L.1
Xu, Z.2
-
76
-
-
77950858208
-
Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified
-
Wilson S.R., Strand M.F., Krapp A., Rise F., Petersen D., Krauss S. Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified. J. Pharm. Biomed. Anal. 2010, 52:707-713.
-
(2010)
J. Pharm. Biomed. Anal.
, vol.52
, pp. 707-713
-
-
Wilson, S.R.1
Strand, M.F.2
Krapp, A.3
Rise, F.4
Petersen, D.5
Krauss, S.6
-
77
-
-
78649720484
-
Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions
-
Xiao C., Ogle S.A., Schumacher M.A., Schilling N., Tokhunts R.A., Orr-Asman M.A., Miller M.L., Robbins D.J., Hollande F., Zavros Y. Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299:G1252-G1265.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
-
-
Xiao, C.1
Ogle, S.A.2
Schumacher, M.A.3
Schilling, N.4
Tokhunts, R.A.5
Orr-Asman, M.A.6
Miller, M.L.7
Robbins, D.J.8
Hollande, F.9
Zavros, Y.10
-
78
-
-
33646453248
-
Hedgehog signaling in prostate cancer
-
Xie J. Hedgehog signaling in prostate cancer. Future Oncol. 2005, 1:331-338.
-
(2005)
Future Oncol.
, vol.1
, pp. 331-338
-
-
Xie, J.1
-
79
-
-
40849096112
-
Hedgehog signaling pathway: Development of antagonists for cancer therapy
-
Xie J. Hedgehog signaling pathway: Development of antagonists for cancer therapy. Curr. Oncol. Rep. 2008, 10:107-113.
-
(2008)
Curr. Oncol. Rep.
, vol.10
, pp. 107-113
-
-
Xie, J.1
-
80
-
-
42949156232
-
Molecular biology of basal and squamous cell carcinomas
-
Xie J. Molecular biology of basal and squamous cell carcinomas. Adv. Exp. Med. Biol. 2008, 624:241-251.
-
(2008)
Adv. Exp. Med. Biol.
, vol.624
, pp. 241-251
-
-
Xie, J.1
-
81
-
-
0142227025
-
Developmental biology informs cancer: The emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers
-
Xie K., Abbruzzese J.L. Developmental biology informs cancer: The emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers. Cancer Cell 2003, 4:245-247.
-
(2003)
Cancer Cell
, vol.4
, pp. 245-247
-
-
Xie, K.1
Abbruzzese, J.L.2
-
82
-
-
33846271799
-
Hedgehog signaling pathway is a possible therapeutic target for gastric cancer
-
Yanai K., Nagai S., Wada J., Yamanaka N., Nakamura M., Torata N., Noshiro H., Tsuneyoshi M., Tanaka M., Katano M. Hedgehog signaling pathway is a possible therapeutic target for gastric cancer. J. Surg. Oncol. 2007, 95:55-62.
-
(2007)
J. Surg. Oncol.
, vol.95
, pp. 55-62
-
-
Yanai, K.1
Nagai, S.2
Wada, J.3
Yamanaka, N.4
Nakamura, M.5
Torata, N.6
Noshiro, H.7
Tsuneyoshi, M.8
Tanaka, M.9
Katano, M.10
-
83
-
-
41049117410
-
Crosstalk of hedgehog and Wnt pathways in gastric cancer
-
Yanai K., Nakamura M., Akiyoshi T., Nagai S., Wada J., Koga K., Noshiro H., Nagai E., Tsuneyoshi M., Tanaka M., Katano M. Crosstalk of hedgehog and Wnt pathways in gastric cancer. Cancer Lett. 2008, 263:145-156.
-
(2008)
Cancer Lett.
, vol.263
, pp. 145-156
-
-
Yanai, K.1
Nakamura, M.2
Akiyoshi, T.3
Nagai, S.4
Wada, J.5
Koga, K.6
Noshiro, H.7
Nagai, E.8
Tsuneyoshi, M.9
Tanaka, M.10
Katano, M.11
-
84
-
-
40949137792
-
Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway
-
Yoo Y.A., Kang M.H., Kim J.S., Oh S.C. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway. Carcinogenesis 2008, 29:480-490.
-
(2008)
Carcinogenesis
, vol.29
, pp. 480-490
-
-
Yoo, Y.A.1
Kang, M.H.2
Kim, J.S.3
Oh, S.C.4
-
85
-
-
43649094590
-
Hedgehog signal activation in oesophageal cancer patients undergoing neoadjuvant chemoradiotherapy
-
Yoshikawa R., Nakano Y., Tao L., Koishi K., Matsumoto T., Sasako M., Tsujimura T., Hashimoto-Tamaoki T., Fujiwara Y. Hedgehog signal activation in oesophageal cancer patients undergoing neoadjuvant chemoradiotherapy. Br. J. Cancer 2008, 98:1670-1674.
-
(2008)
Br. J. Cancer
, vol.98
, pp. 1670-1674
-
-
Yoshikawa, R.1
Nakano, Y.2
Tao, L.3
Koishi, K.4
Matsumoto, T.5
Sasako, M.6
Tsujimura, T.7
Hashimoto-Tamaoki, T.8
Fujiwara, Y.9
-
86
-
-
73449090411
-
Sonic hedgehog relates to colorectal carcinogenesis
-
Yoshikawa K., Shimada M., Miyamoto H., Higashijima J., Miyatani T., Nishioka M., Kurita N., Iwata T., Uehara H. Sonic hedgehog relates to colorectal carcinogenesis. J. Gastroenterol. 2009, 44:1113-1117.
-
(2009)
J. Gastroenterol.
, vol.44
, pp. 1113-1117
-
-
Yoshikawa, K.1
Shimada, M.2
Miyamoto, H.3
Higashijima, J.4
Miyatani, T.5
Nishioka, M.6
Kurita, N.7
Iwata, T.8
Uehara, H.9
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