Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters

Molecular and Cellular Biochemistry

Volumn 337, Issue 1-2, 2010, Pages 185-192

  Fu, Xiangsheng ^a   Deng, Hong ^a   Zhao, Luping ^a   Li, Jing ^b   Zhou, Yongbai ^b   Zhang, Yali ^b  

^a PEOPLE S HOSPITAL OF DEYANG CITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Colorectal cancer; Indian hedgehog; Methylation; Sonic hedgehog

Indexed keywords

BISULFITE; MESSENGER RNA; PROTEIN PATCHED; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ADULT; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PROMOTER REGION; PROTEIN METHYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

ADULT; AGED; BIOPSY; CARCINOMA; CELL CULTURE TECHNIQUES; COLORECTAL NEOPLASMS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; LIGANDS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; TUMOR CELLS, CULTURED;

ERINACEIDAE;

EID: 77949657774     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0298-8     Document Type: Article

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