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Volumn 299, Issue 6, 2010, Pages

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions

Author keywords

Epithelial to mesenchymal transition; IMGE 5 cells; Zonula occludens 1

Indexed keywords

F ACTIN; MUCIN 6; OCCLUDIN; PROTEIN ZO1; SONIC HEDGEHOG PROTEIN; UVOMORULIN;

EID: 78649720484     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00512.2009     Document Type: Article
Times cited : (28)

References (40)
  • 1
  • 2
    • 77953888024 scopus 로고    scopus 로고
    • Disruption of cell junctions induces apoptosis and reduces synthetic activity in lactating goat mammary gland
    • Ben Chedly H, Boutinaud M, Bernier-Dodier P, Marnet P, Lacasse P. Disruption of cell junctions induces apoptosis and reduces synthetic activity in lactating goat mammary gland. J Dairy Sci 93: 2938-2951, 2010.
    • (2010) J Dairy Sci , vol.93 , pp. 2938-2951
    • Ben Chedly, H.1    Boutinaud, M.2    Bernier-Dodier, P.3    Marnet, P.4    Lacasse, P.5
  • 3
    • 0036269067 scopus 로고    scopus 로고
    • E-cadherin is a survival factor for the lactating mouse mammary gland
    • Boussadia O, Kutsch S, Hierholzer A, Delmas V, Kemler R. E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev 115: 53-62, 2002.
    • (2002) Mech Dev , vol.115 , pp. 53-62
    • Boussadia, O.1    Kutsch, S.2    Hierholzer, A.3    Delmas, V.4    Kemler, R.5
  • 4
    • 0036774217 scopus 로고    scopus 로고
    • Cell-cell adhesion and signalling
    • Braga V. Cell-cell adhesion and signalling. Curr Opin Cell Biol 14: 546-556, 2002.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 546-556
    • Braga, V.1
  • 5
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga VM, Machesky LM, Hall A, Hotchin NA. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 137: 1421-1431, 1997.
    • (1997) J Cell Biol , vol.137 , pp. 1421-1431
    • Braga, V.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 7
    • 0035860538 scopus 로고    scopus 로고
    • Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
    • Chamoun Z, Mann R, Nellen D, von Kessler D, Bellotto M, Beachy P, Basler K. Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 293: 2080-2084, 2001.
    • (2001) Science , vol.293 , pp. 2080-2084
    • Chamoun, Z.1    Mann, R.2    Nellen, D.3    Von Kessler, D.4    Bellotto, M.5    Beachy, P.6    Basler, K.7
  • 8
    • 74549154452 scopus 로고    scopus 로고
    • Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
    • Das S, Becker B, Hoffmann F, Mertz J. Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway. BMC Cell Biol 10: 1-18, 2009.
    • (2009) BMC Cell Biol , vol.10 , pp. 1-18
    • Das, S.1    Becker, B.2    Hoffmann, F.3    Mertz, J.4
  • 9
    • 0000752197 scopus 로고
    • Junctional complexes in various epithelia
    • Farquhar MG, Palade GE. Junctional complexes in various epithelia. J Cell Biol 17: 1963.
    • (1963) J Cell Biol , vol.17
    • Farquhar, M.G.1    Palade, G.E.2
  • 10
    • 0030027059 scopus 로고    scopus 로고
    • Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
    • Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 10: 301-312, 1996.
    • (1996) Genes Dev , vol.10 , pp. 301-312
    • Goodrich, L.V.1    Johnson, R.L.2    Milenkovic, L.3    McMahon, J.A.4    Scott, M.P.5
  • 11
    • 0036914924 scopus 로고    scopus 로고
    • Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization
    • Gritli-Linde A, Bei M, Maas R, Zhang X, Linde A, McMahon A. Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development 129: 5323-5337, 2002.
    • (2002) Development , vol.129 , pp. 5323-5337
    • Gritli-Linde, A.1    Bei, M.2    Maas, R.3    Zhang, X.4    Linde, A.5    McMahon, A.6
  • 12
    • 0024095524 scopus 로고
    • The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
    • Gumbiner B, Stevenson B, Grimaldi A. The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J Cell Biol 107: 1575-1587, 1988.
    • (1988) J Cell Biol , vol.107 , pp. 1575-1587
    • Gumbiner, B.1    Stevenson, B.2    Grimaldi, A.3
  • 14
    • 0037386067 scopus 로고    scopus 로고
    • Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells
    • Hollande F, Lee D, Choquet A, Roche S, Baldwin G. Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells. J Cell Sci 116: 1187-1197, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 1187-1197
    • Hollande, F.1    Lee, D.2    Choquet, A.3    Roche, S.4    Baldwin, G.5
  • 15
    • 0037442918 scopus 로고    scopus 로고
    • Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function
    • Hopkins A, Walsh S, Verkade P, Boquet P, Nusrat A. Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. J Cell Sci 116: 725-742, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 725-742
    • Hopkins, A.1    Walsh, S.2    Verkade, P.3    Boquet, P.4    Nusrat, A.5
  • 16
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during the epithelium-mesenchyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J, Matsuda M, Furuse M, Tsukita S. Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci 116: 1959-1967, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 1959-1967
    • Ikenouchi, J.1    Matsuda, M.2    Furuse, M.3    Tsukita, S.4
  • 18
    • 0027253264 scopus 로고
    • Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell
    • Karam SM, Leblond CP. Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell. Anat Rec 236: 259-279, 1993.
    • (1993) Anat Rec , vol.236 , pp. 259-279
    • Karam, S.M.1    Leblond, C.P.2
  • 19
    • 34249802881 scopus 로고    scopus 로고
    • Helicobacter pylori alters the distribution of ZO-1 and p120ctn in primary human gastric epithelial cells
    • Krueger SHT, Kuester D, Kalinski T, Peitz U, Roessner A. Helicobacter pylori alters the distribution of ZO-1 and p120ctn in primary human gastric epithelial cells. Pathol Res Pract 203: 433-444, 2007.
    • (2007) Pathol Res Pract , vol.203 , pp. 433-444
    • Krueger, S.H.T.1    Kuester, D.2    Kalinski, T.3    Peitz, U.4    Roessner, A.5
  • 20
    • 77950823833 scopus 로고    scopus 로고
    • Collagen type I regulates beta-catenin tyrosine phosphorylation and nuclear translocation to promote migration and proliferation of gastric carcinoma cells
    • Li A, Zhou T, Guo L, Si J. Collagen type I regulates beta-catenin tyrosine phosphorylation and nuclear translocation to promote migration and proliferation of gastric carcinoma cells. Oncol Rep 23: 1247-1255, 2010.
    • (2010) Oncol Rep , vol.23 , pp. 1247-1255
    • Li, A.1    Zhou, T.2    Guo, L.3    Si, J.4
  • 21
    • 31544480393 scopus 로고    scopus 로고
    • Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
    • Li XDW, Nail CD, Bailey SK, Kraus MH, Ruppert JM, Lobo-Ruppert SM. Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation. Oncogene 25: 609-621, 2006.
    • (2006) Oncogene , vol.25 , pp. 609-621
    • Li, X.D.W.1    Nail, C.D.2    Bailey, S.K.3    Kraus, M.H.4    Ruppert, J.M.5    Lobo-Ruppert, S.M.6
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K, Schmittgen T. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.1    Schmittgen, T.2
  • 23
    • 47849086547 scopus 로고    scopus 로고
    • Effect and mechanism of the Twist gene on invasion and metastasis of gastric carcinoma cells
    • Luo GQ, Li JH, Wen JF, Zhou YH, Hu YB, Zhou JH. Effect and mechanism of the Twist gene on invasion and metastasis of gastric carcinoma cells. World J Gastroenterol 14: 2487-2493, 2008.
    • (2008) World J Gastroenterol , vol.14 , pp. 2487-2493
    • Luo, G.Q.1    Li, J.H.2    Wen, J.F.3    Zhou, Y.H.4    Hu, Y.B.5    Zhou, J.H.6
  • 24
    • 63249115113 scopus 로고    scopus 로고
    • Loss of tight junction barrier function and its role in cancer metastasis
    • Martin T, Jiang W. Loss of tight junction barrier function and its role in cancer metastasis. Biochim Biophys Acta 1788: 872-891, 2009.
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 872-891
    • Martin, T.1    Jiang, W.2
  • 25
    • 77149179101 scopus 로고    scopus 로고
    • Adherens junction: Molecular architecture and regulation
    • Meng W, Takeichi M. Adherens junction: molecular architecture and regulation. Cold Spring Harb Perspect Biol 1: 1-13, 2009.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. 1-13
    • Meng, W.1    Takeichi, M.2
  • 26
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487, 2004.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 27
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nüsslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 287: 795-801, 1980.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nüsslein-Volhard, C.1    Wieschaus, E.2
  • 28
    • 0035085462 scopus 로고    scopus 로고
    • E-cadherin-mediated cell contact prevents apoptosis of spontaneously immortalized granulosa cells by regulating Akt kinase activity
    • Peluso J, Pappalardo A, Fernandez G. E-cadherin-mediated cell contact prevents apoptosis of spontaneously immortalized granulosa cells by regulating Akt kinase activity. Biol Reprod 64: 1183-1190, 2001.
    • (2001) Biol Reprod , vol.64 , pp. 1183-1190
    • Peluso, J.1    Pappalardo, A.2    Fernandez, G.3
  • 29
    • 34548491399 scopus 로고    scopus 로고
    • Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions
    • Samarin S, Ivanov A, Flatau G, Parkos C, Nusrat A. Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell 18: 3429-3439, 2007.
    • (2007) Mol Biol Cell , vol.18 , pp. 3429-3439
    • Samarin, S.1    Ivanov, A.2    Flatau, G.3    Parkos, C.4    Nusrat, A.5
  • 30
    • 24044493977 scopus 로고    scopus 로고
    • Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins
    • Sander G, Cummins A, Henshall T, Powell B. Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins. FEBS Lett 579: 4851-4855, 2005.
    • (2005) FEBS Lett , vol.579 , pp. 4851-4855
    • Sander, G.1    Cummins, A.2    Henshall, T.3    Powell, B.4
  • 31
    • 16844362860 scopus 로고    scopus 로고
    • Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer
    • Shiotani A, Iishi H, Uedo N, Ishiguro S, Tatsuta M, Nakae Y, Kumamoto M, Merchant JL. Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer. Am J Gastroenterol 100: 581-587, 2005.
    • (2005) Am J Gastroenterol , vol.100 , pp. 581-587
    • Shiotani, A.1    Iishi, H.2    Uedo, N.3    Ishiguro, S.4    Tatsuta, M.5    Nakae, Y.6    Kumamoto, M.7    Merchant, J.L.8
  • 32
    • 18144388632 scopus 로고    scopus 로고
    • Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells
    • Stepan V, Ramamoorthy S, Nitsche H, Zavros Y, Merchant JL, Todisco A. Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells. J Biol Chem 280: 15700-15708, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 15700-15708
    • Stepan, V.1    Ramamoorthy, S.2    Nitsche, H.3    Zavros, Y.4    Merchant, J.L.5    Todisco, A.6
  • 33
    • 19944381545 scopus 로고    scopus 로고
    • Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils
    • Suzuki H, Minegishi Y, Nomoto Y, Ota T, Masaoka T, van den Brink GR, Hibi T. Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils. J Pathol 206: 186-197, 2005.
    • (2005) J Pathol , vol.206 , pp. 186-197
    • Suzuki, H.1    Minegishi, Y.2    Nomoto, Y.3    Ota, T.4    Masaoka, T.5    Van Den Brink, G.R.6    Hibi, T.7
  • 34
    • 0037158748 scopus 로고    scopus 로고
    • Patched acts catalytically to suppress the activity of Smoothened
    • Taipale J, Cooper MK, Maiti T, Beachy PA. Patched acts catalytically to suppress the activity of Smoothened. Nature 418: 892-896, 2002.
    • (2002) Nature , vol.418 , pp. 892-896
    • Taipale, J.1    Cooper, M.K.2    Maiti, T.3    Beachy, P.A.4
  • 35
    • 35648977027 scopus 로고    scopus 로고
    • Hedgehog signaling in development and homeostasis of the gastrointestinal tract
    • Van den Brink GR. Hedgehog signaling in development and homeostasis of the gastrointestinal tract. Physiol Rev 87: 1343-1375, 2007.
    • (2007) Physiol Rev , vol.87 , pp. 1343-1375
    • Van Den Brink, G.R.1
  • 37
    • 0035140977 scopus 로고    scopus 로고
    • Actin dynamics and cell-cell adhesion in epithelia
    • Vasioukhin V, Fuchs E. Actin dynamics and cell-cell adhesion in epithelia. Curr Opin Cell Biol 13: 76-84, 2001.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 76-84
    • Vasioukhin, V.1    Fuchs, E.2
  • 39
    • 4444253507 scopus 로고    scopus 로고
    • Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells
    • Yamada A, Irie K, Fukuhara A, Ooshio T, Takai Y. Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells. Genes Cells 9: 843-855, 2004.
    • (2004) Genes Cells , vol.9 , pp. 843-855
    • Yamada, A.1    Irie, K.2    Fukuhara, A.3    Ooshio, T.4    Takai, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.