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Volumn 135, Issue 5, 2012, Pages 599-613

Implication of microsatellite instability in human gastric cancers

Author keywords

Gastric cancer; Microsatellite instability; Mismatch repair; Msi h phenotype; Mtmsi; Tumour suppression

Indexed keywords

ANTINEOPLASTIC AGENT; ATR PROTEIN; BLOOM SYNDROME HELICASE; CISPLATIN; EPHRIN B2; FLUOROURACIL; MICROSATELLITE DNA; MISMATCH REPAIR PROTEIN; MITOCHONDRIAL DNA; MUCIN; RIZ PROTEIN; TRANSCRIPTION FACTOR RUNX3; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84863223860     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (28)

References (127)
  • 3
    • 0033808899 scopus 로고    scopus 로고
    • Evolutionary dynamics of microsatellite DNA
    • Schlotterer C. Evolutionary dynamics of microsatellite DNA. Chromosoma 2000; 109: 365-71.
    • (2000) Chromosoma , vol.109 , pp. 365-371
    • Schlotterer, C.1
  • 4
    • 33644757018 scopus 로고    scopus 로고
    • Alterations of tumour suppressor and tumourrelated genes in the development and progression of gastric cancer
    • Tamura G. Alterations of tumour suppressor and tumourrelated genes in the development and progression of gastric cancer. World J Gastroenterol 2006; 12: 192-8.
    • (2006) World J Gastroenterol , vol.12 , pp. 192-198
    • Tamura, G.1
  • 5
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 6
    • 0242266515 scopus 로고    scopus 로고
    • Genetic classification of intestinal-type and diffuse-type gastric cancers based on chromosomal loss and microsatellite instability
    • Kim KM, Kwon MS, Hong SJ, Min KO, Seo EJ, Lee KY, et al. Genetic classification of intestinal-type and diffuse-type gastric cancers based on chromosomal loss and microsatellite instability. Virchows Arch 2003; 443: 491-500.
    • (2003) Virchows Arch , vol.443 , pp. 491-500
    • Kim, K.M.1    Kwon, M.S.2    Hong, S.J.3    Min, K.O.4    Seo, E.J.5    Lee, K.Y.6
  • 7
    • 0033857247 scopus 로고    scopus 로고
    • Microsatellite variability differs between dinucleotide repeat motifsevidence from Drosophila melanogaster
    • Bachtrog D, Agis M, Imhof M, Schlotterer C. Microsatellite variability differs between dinucleotide repeat motifsevidence from Drosophila melanogaster. Mol Biol Evol 2000; 17: 1277-85.
    • (2000) Mol Biol Evol , vol.17 , pp. 1277-1285
    • Bachtrog, D.1    Agis, M.2    Imhof, M.3    Schlotterer, C.4
  • 8
    • 77649232847 scopus 로고    scopus 로고
    • Mutational dynamics of microsatellites
    • Bhargava A, Feuntes FF. Mutational dynamics of microsatellites. Mol Biotechnol 2010; 44: 250-66.
    • (2010) Mol Biotechnol , vol.44 , pp. 250-266
    • Bhargava, A.1    Feuntes, F.F.2
  • 9
    • 33749991391 scopus 로고    scopus 로고
    • The rise, fall and renaissance of microsatellites in eukaryotic genomes
    • Buschiazzo E, Gemmell NJ. The rise, fall and renaissance of microsatellites in eukaryotic genomes. Bioessays 2006; 28: 1040-50.
    • (2006) Bioessays , vol.28 , pp. 1040-1050
    • Buschiazzo, E.1    Gemmell, N.J.2
  • 10
    • 0002441088 scopus 로고    scopus 로고
    • Mechanistic basis for microsatellite instability
    • Goldstein DB, Schlotterer C, editors, Oxford: Oxford University Press
    • Eisen JA. Mechanistic basis for microsatellite instability. In: Goldstein DB, Schlotterer C, editors. Microsatellites: Evolution and applications. Oxford: Oxford University Press; 1999. p. 34-48.
    • (1999) Microsatellites: Evolution and Applications , pp. 34-48
    • Eisen, J.A.1
  • 11
    • 0027306173 scopus 로고
    • Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
    • Strand M, Prolla TA, Liskay RM, Petes TD. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 1993; 365: 274-6.
    • (1993) Nature , vol.365 , pp. 274-276
    • Strand, M.1    Prolla, T.A.2    Liskay, R.M.3    Petes, T.D.4
  • 12
    • 0035994594 scopus 로고    scopus 로고
    • Climatic effect on microsatellite diversity in wild emmer wheat, Triticum dicoccoides, at Yehudiyya microsite, Israel
    • Li YC, Roder MS, Fahima T, Kirzhner VM, Beiles A, Korol AB, et al. Climatic effect on microsatellite diversity in wild emmer wheat, Triticum dicoccoides, at Yehudiyya microsite, Israel. Heredity 2002; 89: 127-32.
    • (2002) Heredity , vol.89 , pp. 127-132
    • Li, Y.C.1    Roder, M.S.2    Fahima, T.3    Kirzhner, V.M.4    Beiles, A.5    Korol, A.B.6
  • 14
    • 0034933419 scopus 로고    scopus 로고
    • Microsatellite instability
    • Atkin NB. Microsatellite instability. Cytogenet Cell Genet 2001; 92: 177-81.
    • (2001) Cytogenet Cell Genet , vol.92 , pp. 177-181
    • Atkin, N.B.1
  • 17
    • 0028169368 scopus 로고
    • P53 mutations and microsatellite instability in sporadic gastric cancer: When guardians fail
    • Strickler JG, Zheng J, Shu Q, Burgart LJ, Alberts SR, Shibata D. p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail. Cancer Res 1994; 54: 4750-5.
    • (1994) Cancer Res , vol.54 , pp. 4750-4755
    • Strickler, J.G.1    Zheng, J.2    Shu, Q.3    Burgart, L.J.4    Alberts, S.R.5    Shibata, D.6
  • 18
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, et al. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58: 5248-57.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5    Burt, R.W.6
  • 19
    • 20144376089 scopus 로고    scopus 로고
    • Two modes of microsatellite instability in humancancer: Differential connection of defective DNA mismatch repair to dinucleotide repeat instability
    • Oda S, Maehara Y, Ikeda Y, Oki E, Egashira A, Okamura Y, et al. Two modes of microsatellite instability in humancancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability. Nucleic Acids Res 2005; 33: 1628-36.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1628-1636
    • Oda, S.1    Maehara, Y.2    Ikeda, Y.3    Oki, E.4    Egashira, A.5    Okamura, Y.6
  • 21
    • 33644998539 scopus 로고    scopus 로고
    • Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers
    • Beghelli S, de Manzoni G, Barbi S, Tomezzoli A, Roviello F, Gregoria CD, et al. Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers. Surgery 2006; 139: 347-56.
    • (2006) Surgery , vol.139 , pp. 347-356
    • Beghelli, S.1    de Manzoni, G.2    Barbi, S.3    Tomezzoli, A.4    Roviello, F.5    Gregoria, C.D.6
  • 22
    • 0032870152 scopus 로고    scopus 로고
    • Marked differences in the frequency of microsatellite instability in gastric cancer from different countries
    • Sepulveda AR, Santos AC, Yamaoka Y, Wu L, Gutierrez O, Kim JG, et al. Marked differences in the frequency of microsatellite instability in gastric cancer from different countries. Am J Gastroenterol 1999; 94: 3034-8.
    • (1999) Am J Gastroenterol , vol.94 , pp. 3034-3038
    • Sepulveda, A.R.1    Santos, A.C.2    Yamaoka, Y.3    Wu, L.4    Gutierrez, O.5    Kim, J.G.6
  • 23
    • 0033802550 scopus 로고    scopus 로고
    • Microsatellite instability, prognosis and metastasis in gastric cancers from a low risk population
    • Schneider BG, Bravo JC, Roa JC, Roa I, Kim MC, Lee KM, et al. Microsatellite instability, prognosis and metastasis in gastric cancers from a low risk population. Int J Cancer 2000; 89: 444-52.
    • (2000) Int J Cancer , vol.89 , pp. 444-452
    • Schneider, B.G.1    Bravo, J.C.2    Roa, J.C.3    Roa, I.4    Kim, M.C.5    Lee, K.M.6
  • 24
    • 0035923269 scopus 로고    scopus 로고
    • Microsatellite instability is a genetic marker for the development of multiple gastric cancers
    • Miyoshi E, Haruma K, Hiyama T, Tanaka S, Yoshihara M, Shimamoto F, et al. Microsatellite instability is a genetic marker for the development of multiple gastric cancers. Int J Cancer 2001; 95: 350-3.
    • (2001) Int J Cancer , vol.95 , pp. 350-353
    • Miyoshi, E.1    Haruma, K.2    Hiyama, T.3    Tanaka, S.4    Yoshihara, M.5    Shimamoto, F.6
  • 25
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
    • Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 1995; 268: 1336-8.
    • (1995) Science , vol.268 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3    Parsons, R.4    Sun, L.5    Lutterbaugh, J.6
  • 26
    • 16144368515 scopus 로고    scopus 로고
    • Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours
    • Souza RF, Appel R, Yin J, Wang S, Smolinski KN, Abraham JM, et al. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat Genet 1996; 14: 255-7.
    • (1996) Nat Genet , vol.14 , pp. 255-257
    • Souza, R.F.1    Appel, R.2    Yin, J.3    Wang, S.4    Smolinski, K.N.5    Abraham, J.M.6
  • 28
    • 44649157590 scopus 로고    scopus 로고
    • Gastric cancer with high level microsatellite instability: Target gene mutations, clinicopathologic features and long term survival
    • Falchetti M, Saieva C, Lupi R, Masala G, Rizzolo P, Zanna I, et al. Gastric cancer with high level microsatellite instability: target gene mutations, clinicopathologic features and long term survival. Hum Pathol 2008; 39: 925-32.
    • (2008) Hum Pathol , vol.39 , pp. 925-932
    • Falchetti, M.1    Saieva, C.2    Lupi, R.3    Masala, G.4    Rizzolo, P.5    Zanna, I.6
  • 30
    • 77951094639 scopus 로고    scopus 로고
    • Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability
    • Song SY, Kang MR, Yoo NJ, Lee SH. Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability. APMIS 2010; 118: 389-93.
    • (2010) APMIS , vol.118 , pp. 389-393
    • Song, S.Y.1    Kang, M.R.2    Yoo, N.J.3    Lee, S.H.4
  • 31
    • 33846239265 scopus 로고    scopus 로고
    • High EPHB2 mutation rate in gastric but not endometrial tumours with microsatellite instability
    • Davalos V, Dopeso H, Velho S, Ferreira AM, Cirnes L, Diaz- Chico N, et al. High EPHB2 mutation rate in gastric but not endometrial tumours with microsatellite instability. Oncology 2007; 26: 308-11.
    • (2007) Oncology , vol.26 , pp. 308-311
    • Davalos, V.1    Dopeso, H.2    Velho, S.3    Ferreira, A.M.4    Cirnes, L.5    Diaz-Chico, N.6
  • 32
    • 0034283031 scopus 로고    scopus 로고
    • Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability
    • Piao Z, Fang W, Malkhosyan S, Kim H, Horii A, Perucho M, et al. Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability. Cancer Res 2000; 60: 4701-4.
    • (2000) Cancer Res , vol.60 , pp. 4701-4704
    • Piao, Z.1    Fang, W.2    Malkhosyan, S.3    Kim, H.4    Horii, A.5    Perucho, M.6
  • 33
    • 10344225054 scopus 로고    scopus 로고
    • MRE11 expression is impaired in gastric cancer with microsatellite instability
    • Ottini L, Falchetti M, Saieva C, Marco MD, Masala G, Zanna I, et al. MRE11 expression is impaired in gastric cancer with microsatellite instability. Carcinogenesis 2004; 25: 2337-43.
    • (2004) Carcinogenesis , vol.25 , pp. 2337-2343
    • Ottini, L.1    Falchetti, M.2    Saieva, C.3    Marco, M.D.4    Masala, G.5    Zanna, I.6
  • 34
    • 0035503171 scopus 로고    scopus 로고
    • Somatic mutations in the DNA damageresponse genes ATR and CHK1 in sporadic stomach tumours with microsatellite instability
    • Menoyo A, Alazzouzi H, Espin E, Armengol M, Yamamoto H, Schwartz S Jr. Somatic mutations in the DNA damageresponse genes ATR and CHK1 in sporadic stomach tumours with microsatellite instability. Cancer Res 2001; 61: 7727-30.
    • (2001) Cancer Res , vol.61 , pp. 7727-7730
    • Menoyo, A.1    Alazzouzi, H.2    Espin, E.3    Armengol, M.4    Yamamoto, H.5    Schwartz Jr., S.6
  • 35
    • 77957111494 scopus 로고    scopus 로고
    • Mutational and expressional analysis of RFC3, a clamp loader in DNA replication, in gastric and colorectal cancers
    • Kim YR, Song SY, Kim SS, An CH, Lee SH, Yoo NJ. Mutational and expressional analysis of RFC3, a clamp loader in DNA replication, in gastric and colorectal cancers. Hum Pathol 2010; 41: 1431-7.
    • (2010) Hum Pathol , vol.41 , pp. 1431-1437
    • Kim, Y.R.1    Song, S.Y.2    Kim, S.S.3    An, C.H.4    Lee, S.H.5    Yoo, N.J.6
  • 36
    • 0035844994 scopus 로고    scopus 로고
    • Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype
    • Ohmiya N, Matsumoto S, Yamamoto H, Baranovskaya S, Malkhosyan SR, Perucho M. Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype. Gene 2001; 272: 301-13.
    • (2001) Gene , vol.272 , pp. 301-313
    • Ohmiya, N.1    Matsumoto, S.2    Yamamoto, H.3    Baranovskaya, S.4    Malkhosyan, S.R.5    Perucho, M.6
  • 37
    • 56249140407 scopus 로고    scopus 로고
    • Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability
    • Kim MS, Kim SS, Ahn CH, Yoo NJ, Lee SH. Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability. Hum Pathol 2009; 40: 58-64.
    • (2009) Hum Pathol , vol.40 , pp. 58-64
    • Kim, M.S.1    Kim, S.S.2    Ahn, C.H.3    Yoo, N.J.4    Lee, S.H.5
  • 38
    • 0034942972 scopus 로고    scopus 로고
    • Microsatellite alterations and target gene mutations in the early stages of multiple gastric cancer
    • Ogata S, Tamura G, Endoh Y, Sakata K, Ohmura K, Motoyama T. Microsatellite alterations and target gene mutations in the early stages of multiple gastric cancer. J Pathol 2001; 194: 334-40.
    • (2001) J Pathol , vol.194 , pp. 334-340
    • Ogata, S.1    Tamura, G.2    Endoh, Y.3    Sakata, K.4    Ohmura, K.5    Motoyama, T.6
  • 39
    • 64549101639 scopus 로고    scopus 로고
    • Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
    • Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, et al. Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 2009; 217: 702-6.
    • (2009) J Pathol , vol.217 , pp. 702-706
    • Kang, M.R.1    Kim, M.S.2    Oh, J.E.3    Kim, Y.R.4    Song, S.Y.5    Kim, S.S.6
  • 40
    • 18744404031 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype
    • Calin G, Ranzani GN, Amadori D, Herlea V, Matei I, Barbanti- Brodano G, et al. Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype. BMC Genet 2001; 2: 1471-7.
    • (2001) BMC Genet , vol.2 , pp. 1471-1477
    • Calin, G.1    Ranzani, G.N.2    Amadori, D.3    Herlea, V.4    Matei, I.5    Barbanti-Brodano, G.6
  • 41
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997; 275: 967-9.
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3    Li, Y.4    Sawai, H.5    Reed, J.C.6
  • 42
    • 0035881961 scopus 로고    scopus 로고
    • Instabilotyping: Comprehensive identification of frameshift mutations caused by coding region microsatellite instability
    • Mori Y, Yin J, Rashid A, Leggett BA, Young J, Simms L, et al. Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. Cancer Res 2001; 61: 6046-9.
    • (2001) Cancer Res , vol.61 , pp. 6046-6049
    • Mori, Y.1    Yin, J.2    Rashid, A.3    Leggett, B.A.4    Young, J.5    Simms, L.6
  • 43
    • 28544450494 scopus 로고    scopus 로고
    • Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumours
    • Alazzouzi H, Davalos V, Kokko A, Domingo E, Woerner SM, Wilson AJ, et al. Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumours. Cancer Res 2005; 65: 10170-3.
    • (2005) Cancer Res , vol.65 , pp. 10170-10173
    • Alazzouzi, H.1    Davalos, V.2    Kokko, A.3    Domingo, E.4    Woerner, S.M.5    Wilson, A.J.6
  • 44
    • 0037987704 scopus 로고    scopus 로고
    • Promoter methylation of TGFβ receptor I and mutation of TGF β receptor II are frequent events in MSI sporadic gastric carcinomas
    • Pinto M, Oliveira C, Cirnes L, Machado JC, Ramires M, Nogueira A, et al. Promoter methylation of TGFβ receptor I and mutation of TGF β receptor II are frequent events in MSI sporadic gastric carcinomas. J Pathol 2003; 200: 32-8.
    • (2003) J Pathol , vol.200 , pp. 32-38
    • Pinto, M.1    Oliveira, C.2    Cirnes, L.3    Machado, J.C.4    Ramires, M.5    Nogueira, A.6
  • 45
    • 0031710793 scopus 로고    scopus 로고
    • The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different target genes-a study of TGFβRII, IGFIIR and BAX genes
    • Oliveira C, Seruca R, Seixas M, Sobrinho SM. The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different target genes-a study of TGFβRII, IGFIIR and BAX genes. Am J Pathol 1998; 153: 1211-9.
    • (1998) Am J Pathol , vol.153 , pp. 1211-1219
    • Oliveira, C.1    Seruca, R.2    Seixas, M.3    Sobrinho, S.M.4
  • 46
    • 33645510806 scopus 로고    scopus 로고
    • Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract
    • Mongiat-Artus P, Miquel C, Van der Aa M, Buhard O, Hamelin R, Soliman H, et al. Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract. Oncogene 2006; 25: 2113-8.
    • (2006) Oncogene , vol.25 , pp. 2113-2118
    • Mongiat-Artus, P.1    Miquel, C.2    van der Aa, M.3    Buhard, O.4    Hamelin, R.5    Soliman, H.6
  • 47
    • 3142658762 scopus 로고    scopus 로고
    • Hypersensitivity of tumour cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin
    • Li HR, Shagisultanova EI, Yamashita K, Piao Z, Perucho M, Malkhosyan SR. Hypersensitivity of tumour cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin. Cancer Res 2004; 64: 4760-7.
    • (2004) Cancer Res , vol.64 , pp. 4760-4767
    • Li, H.R.1    Shagisultanova, E.I.2    Yamashita, K.3    Piao, Z.4    Perucho, M.5    Malkhosyan, S.R.6
  • 48
    • 35848954749 scopus 로고    scopus 로고
    • Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer
    • Lee HS, Choe G, Park KU, Park DJ, Yang HK, Lee BL, et al. Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer. Int J Oncol 2007; 31: 859-66.
    • (2007) Int J Oncol , vol.31 , pp. 859-866
    • Lee, H.S.1    Choe, G.2    Park, K.U.3    Park, D.J.4    Yang, H.K.5    Lee, B.L.6
  • 49
    • 0036193127 scopus 로고    scopus 로고
    • Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer
    • Ebert MP, Fei G, Kahmann S, Muller O, Yu J, Sung JJ et al. Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer. Carcinogenesis 2002; 23: 87-91.
    • (2002) Carcinogenesis , vol.23 , pp. 87-91
    • Ebert, M.P.1    Fei, G.2    Kahmann, S.3    Muller, O.4    Yu, J.5    Sung, J.J.6
  • 50
    • 25144470101 scopus 로고    scopus 로고
    • EphB2 expression across 138 human tumour types in a tissue microarray: High levels of expression in gastrointestinal cancer
    • Lugli A, Spichtin H, Maurer R, Mirlacher M, Kiefer J, Huusko P, et al. EphB2 expression across 138 human tumour types in a tissue microarray: high levels of expression in gastrointestinal cancer. Clin Cancer Res 2005; 11: 6450-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 6450-6458
    • Lugli, A.1    Spichtin, H.2    Maurer, R.3    Mirlacher, M.4    Kiefer, J.5    Huusko, P.6
  • 51
    • 4544341573 scopus 로고    scopus 로고
    • Detection of frameshift mutations of RIZ in gastric cancers with microsatellite instability
    • Pan KF, Lu YY, Liu WG, Zhang L, You WC. Detection of frameshift mutations of RIZ in gastric cancers with microsatellite instability. World J Gastroenterol 2004; 10: 2719-22.
    • (2004) World J Gastroenterol , vol.10 , pp. 2719-2722
    • Pan, K.F.1    Lu, Y.Y.2    Liu, W.G.3    Zhang, L.4    You, W.C.5
  • 52
    • 3042782819 scopus 로고    scopus 로고
    • Microsatellites: Simple sequences with complex evolution
    • Ellegren H. Microsatellites: simple sequences with complex evolution. Nat Rev Genet 2004; 5: 435-45.
    • (2004) Nat Rev Genet , vol.5 , pp. 435-445
    • Ellegren, H.1
  • 53
    • 76549111046 scopus 로고    scopus 로고
    • Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes
    • Shah SN, Hile SE, Eckert KA. Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes. Cancer Res 2010; 70: 431-5.
    • (2010) Cancer Res , vol.70 , pp. 431-435
    • Shah, S.N.1    Hile, S.E.2    Eckert, K.A.3
  • 54
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science 2002; 296: 1644-6.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 55
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14: 1837-51.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 56
    • 0033780630 scopus 로고    scopus 로고
    • Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating betacatenin/TCF signalling
    • Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, et al. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating betacatenin/TCF signalling. Nat Genet 2000; 26: 146-7.
    • (2000) Nat Genet , vol.26 , pp. 146-147
    • Liu, W.1    Dong, X.2    Mai, M.3    Seelan, R.S.4    Taniguchi, K.5    Krishnadath, K.K.6
  • 58
    • 0034865228 scopus 로고    scopus 로고
    • Genetic alterations in the human Tcf-4 gene in Japanese patients with sporadic gastrointestinal cancers with microsatellite instability
    • Saeki H, Tanaka S, Tokunaga E, Kawaguchi H, Ikeda Y, Maehara Y, et al. Genetic alterations in the human Tcf-4 gene in Japanese patients with sporadic gastrointestinal cancers with microsatellite instability. Oncology 2001; 61: 156-61.
    • (2001) Oncology , vol.61 , pp. 156-161
    • Saeki, H.1    Tanaka, S.2    Tokunaga, E.3    Kawaguchi, H.4    Ikeda, Y.5    Maehara, Y.6
  • 59
    • 36048965762 scopus 로고    scopus 로고
    • The relationship between frameshift mutations of transforming growth factor-β type II receptor, insulin growth factor II receptor, bcl-2 associated X protein, E2F4 and microsatellite instability in gastric carcinoma
    • Chen GT, Zhu ZG, Yin HR, Liu BY, Ji J, Zhang J, et al. The relationship between frameshift mutations of transforming growth factor-β type II receptor, insulin growth factor II receptor, bcl-2 associated X protein, E2F4 and microsatellite instability in gastric carcinoma. Zhongua Wai Ke Za Zhi 2006; 44: 344-8.
    • (2006) Zhongua Wai Ke Za Zhi , vol.44 , pp. 344-348
    • Chen, G.T.1    Zhu, Z.G.2    Yin, H.R.3    Liu, B.Y.4    Ji, J.5    Zhang, J.6
  • 60
    • 0017760671 scopus 로고
    • Hereditary multiple fibrofolliculomas with trichodiscomas and achrochordons
    • Birt AR, Hogg GR, Dube WJ. Hereditary multiple fibrofolliculomas with trichodiscomas and achrochordons. Arch Dermatol 1977; 113: 1674-7.
    • (1977) Arch Dermatol , vol.113 , pp. 1674-1677
    • Birt, A.R.1    Hogg, G.R.2    Dube, W.J.3
  • 61
    • 0000939691 scopus 로고    scopus 로고
    • Mutations in a novel gene lead to kidney tumours, lung wall defects and benign tumours of the hair follicle in patients with Birt-Hogg-Dube syndrome
    • Nickerson ML, Warren MB, Toro JR, Matrosova V, Glenn G, Turner ML, et al. Mutations in a novel gene lead to kidney tumours, lung wall defects and benign tumours of the hair follicle in patients with Birt-Hogg-Dube syndrome. Cancer Cell 2002; 2: 157-64.
    • (2002) Cancer Cell , vol.2 , pp. 157-164
    • Nickerson, M.L.1    Warren, M.B.2    Toro, J.R.3    Matrosova, V.4    Glenn, G.5    Turner, M.L.6
  • 63
    • 33847299597 scopus 로고    scopus 로고
    • Birt-Hogg-Dubé (BHD) gene mutations in human gastric cancer with high frequency microsatellite instability
    • Jiang W, Fujii H, Matsumoto T, Ohtsuji N, Tsurumaru M, Hino O. Birt-Hogg-Dubé (BHD) gene mutations in human gastric cancer with high frequency microsatellite instability. Cancer Lett 2007; 248: 103-11.
    • (2007) Cancer Lett , vol.248 , pp. 103-111
    • Jiang, W.1    Fujii, H.2    Matsumoto, T.3    Ohtsuji, N.4    Tsurumaru, M.5    Hino, O.6
  • 64
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005; 6: 505-10.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 65
    • 45049083880 scopus 로고    scopus 로고
    • Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
    • Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ. Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 2008; 39: 1059-63.
    • (2008) Hum Pathol , vol.39 , pp. 1059-1063
    • Kim, M.S.1    Jeong, E.G.2    Ahn, C.H.3    Kim, S.S.4    Lee, S.H.5    Yoo, N.J.6
  • 66
    • 0038325528 scopus 로고    scopus 로고
    • Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherinin gastric carcinomas with microsatellite instability
    • Kim H, Kim YH, Kim SE, Kim NG, Noh SH, Kim H. Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherinin gastric carcinomas with microsatellite instability. J Pathol 2003; 200: 23-31.
    • (2003) J Pathol , vol.200 , pp. 23-31
    • Kim, H.1    Kim, Y.H.2    Kim, S.E.3    Kim, N.G.4    Noh, S.H.5    Kim, H.6
  • 68
    • 0029941476 scopus 로고    scopus 로고
    • Microsatellite instability: The mutator that mutates the other mutator
    • Perucho M. Microsatellite instability: the mutator that mutates the other mutator. Nature Med 1996; 2: 630-1.
    • (1996) Nature Med , vol.2 , pp. 630-631
    • Perucho, M.1
  • 69
    • 68949161979 scopus 로고    scopus 로고
    • Correlation of microsatellite instability at multiple loci with long term survival in advanced gastric carcinoma
    • Corso G, Pedrazzani C, Marelli D, Pascale V, Pinto E, Roviello F. Correlation of microsatellite instability at multiple loci with long term survival in advanced gastric carcinoma. Arch Surg 2009; 144: 722-7.
    • (2009) Arch Surg , vol.144 , pp. 722-727
    • Corso, G.1    Pedrazzani, C.2    Marelli, D.3    Pascale, V.4    Pinto, E.5    Roviello, F.6
  • 70
    • 0033870284 scopus 로고    scopus 로고
    • Microsatellite instability in gastric intestinal metaplasia in patients with and without gastric cancer
    • Leung WK, Kim JJ, Kim JG, Graham DY, Sepulveda AR. Microsatellite instability in gastric intestinal metaplasia in patients with and without gastric cancer. Am J Pathol 2000; 156: 537-43.
    • (2000) Am J Pathol , vol.156 , pp. 537-543
    • Leung, W.K.1    Kim, J.J.2    Kim, J.G.3    Graham, D.Y.4    Sepulveda, A.R.5
  • 71
    • 42949177113 scopus 로고    scopus 로고
    • Clinicopathologic implications of genetic instability in intestinal-type gastric cancer and intestinal metaplasia as a precancerous lesion
    • Zaky AH, Watari J, Tanabe H, Sato R, Moriichi K, Tanaka A, et al. Clinicopathologic implications of genetic instability in intestinal-type gastric cancer and intestinal metaplasia as a precancerous lesion. Am J Clin Pathol 2008; 129: 613-21.
    • (2008) Am J Clin Pathol , vol.129 , pp. 613-621
    • Zaky, A.H.1    Watari, J.2    Tanabe, H.3    Sato, R.4    Moriichi, K.5    Tanaka, A.6
  • 72
    • 0034108472 scopus 로고    scopus 로고
    • Clinical usefulness of microsatellite instability for the prediction of gastric adenoma or adenocarcinoma in patients with chronic gastritis
    • Kashiwagi K, Watanabe M, Ezaki T, Kanai T, Ishii H, Mukai M, et al. Clinical usefulness of microsatellite instability for the prediction of gastric adenoma or adenocarcinoma in patients with chronic gastritis. Br J Cancer 2000; 82: 1814-8.
    • (2000) Br J Cancer , vol.82 , pp. 1814-1818
    • Kashiwagi, K.1    Watanabe, M.2    Ezaki, T.3    Kanai, T.4    Ishii, H.5    Mukai, M.6
  • 74
    • 0036089129 scopus 로고    scopus 로고
    • Distinct clinical features and outcomes of gastric cancers with microsatellite instability
    • Lee HS, Choi SI, Lee HK, Kim HS, Yang HK, Kang GH, et al. Distinct clinical features and outcomes of gastric cancers with microsatellite instability. Mod Pathol 2002; 15: 632-40.
    • (2002) Mod Pathol , vol.15 , pp. 632-640
    • Lee, H.S.1    Choi, S.I.2    Lee, H.K.3    Kim, H.S.4    Yang, H.K.5    Kang, G.H.6
  • 75
    • 0034879583 scopus 로고    scopus 로고
    • The role of histological investigation in prognostic evaluation of advanced gastric cancer. Analysis of histological structure and molecular changes compared with invasive pattern and stage
    • Chiaravalli AM, Cornaggia M, Furlan D, Capella C, Fiocca R, Tagliabue G, et al. The role of histological investigation in prognostic evaluation of advanced gastric cancer. Analysis of histological structure and molecular changes compared with invasive pattern and stage. Virchows Arch 2001; 439: 158-69.
    • (2001) Virchows Arch , vol.439 , pp. 158-169
    • Chiaravalli, A.M.1    Cornaggia, M.2    Furlan, D.3    Capella, C.4    Fiocca, R.5    Tagliabue, G.6
  • 76
    • 28244488137 scopus 로고    scopus 로고
    • Differences in genomic instability between intestinal- and diffuse- type gastric cancer
    • Vauhkonen M, Vauhkonen H, Sajantila A, Sipponen P. Differences in genomic instability between intestinal- and diffuse- type gastric cancer. Gastric Cancer 2005; 8: 238-44.
    • (2005) Gastric Cancer , vol.8 , pp. 238-244
    • Vauhkonen, M.1    Vauhkonen, H.2    Sajantila, A.3    Sipponen, P.4
  • 77
    • 0031057463 scopus 로고    scopus 로고
    • Assessment of microsatellite alterations in young patients with gastric adenocarcinoma
    • Hayden JD, Cawkwell L, Sue-Ling H, Johnston D, Dixon MF, Quirke P, et al. Assessment of microsatellite alterations in young patients with gastric adenocarcinoma. Cancer 1997; 79: 684-7.
    • (1997) Cancer , vol.79 , pp. 684-687
    • Hayden, J.D.1    Cawkwell, L.2    Sue-Ling, H.3    Johnston, D.4    Dixon, M.F.5    Quirke, P.6
  • 78
    • 0035124351 scopus 로고    scopus 로고
    • Genetic and epigenetic changes in stomach cancer
    • Yokozaki H, Yasui W, Tahara E. Genetic and epigenetic changes in stomach cancer. Int Rev Cytol 2001; 204: 49-95.
    • (2001) Int Rev Cytol , vol.204 , pp. 49-95
    • Yokozaki, H.1    Yasui, W.2    Tahara, E.3
  • 79
    • 0032794337 scopus 로고    scopus 로고
    • Medullary-type poorly differentiated adenocarcinoma of the large bowel: A distinct clinicopathologic entity characterized by microsatellite instability and improved survival
    • Lanza G, Gafa R, Matteuzzi M, Santini A. Medullary-type poorly differentiated adenocarcinoma of the large bowel: a distinct clinicopathologic entity characterized by microsatellite instability and improved survival. J Clin Oncol 1999; 17: 2429-38.
    • (1999) J Clin Oncol , vol.17 , pp. 2429-2438
    • Lanza, G.1    Gafa, R.2    Matteuzzi, M.3    Santini, A.4
  • 80
    • 34249797029 scopus 로고    scopus 로고
    • Clinicopathological and molecular characteristics of gastric and colorectal carcinomas in elderly
    • Arai T, Takubo K. Clinicopathological and molecular characteristics of gastric and colorectal carcinomas in elderly. Pathol Int 2007; 57: 303-14.
    • (2007) Pathol Int , vol.57 , pp. 303-314
    • Arai, T.1    Takubo, K.2
  • 82
    • 77954672135 scopus 로고    scopus 로고
    • Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly
    • Arai T, Kasahara I, Sawabe M, Honma N, Aida J, Tabubo K. Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly. Geriatr Gerontol Int 2010; 10: S207-12.
    • (2010) Geriatr Gerontol Int , vol.10
    • Arai, T.1    Kasahara, I.2    Sawabe, M.3    Honma, N.4    Aida, J.5    Tabubo, K.6
  • 83
    • 33750716501 scopus 로고    scopus 로고
    • Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients
    • Sasao S, Hiyama T, Tanaka S, Yoshihara M, Yasui W, Chayama K. Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients. Oncol Rep 2006; 16: 11-5.
    • (2006) Oncol Rep , vol.16 , pp. 11-15
    • Sasao, S.1    Hiyama, T.2    Tanaka, S.3    Yoshihara, M.4    Yasui, W.5    Chayama, K.6
  • 85
    • 33646596947 scopus 로고    scopus 로고
    • Clinicopathologic characteristics and surgical outcomes of mucinous gastric carcinoma
    • Kunisaki C, Akiyama H, Nomura M, Matsuda G, Otsuka Y, Ono HA, et al. Clinicopathologic characteristics and surgical outcomes of mucinous gastric carcinoma. Ann Surg Oncol 2006; 13: 836-42.
    • (2006) Ann Surg Oncol , vol.13 , pp. 836-842
    • Kunisaki, C.1    Akiyama, H.2    Nomura, M.3    Matsuda, G.4    Otsuka, Y.5    Ono, H.A.6
  • 86
    • 0036681207 scopus 로고    scopus 로고
    • Mucin phenotype and microsatellite instability in early multiple gastric cancers
    • Takahashi H, Endo T, Yamashita K, Arimura Y, Yamamoto H, Sasaki S, et al. Mucin phenotype and microsatellite instability in early multiple gastric cancers. Int J Cancer 2002; 100: 419-24.
    • (2002) Int J Cancer , vol.100 , pp. 419-424
    • Takahashi, H.1    Endo, T.2    Yamashita, K.3    Arimura, Y.4    Yamamoto, H.5    Sasaki, S.6
  • 87
    • 8144228769 scopus 로고    scopus 로고
    • Microsatellite instability in gastric MALT lymphoma
    • Niv E, Bomstein Y, Bernheim J, Lishner M. Microsatellite instability in gastric MALT lymphoma. Mod Pathol 2004; 17: 1407-13.
    • (2004) Mod Pathol , vol.17 , pp. 1407-1413
    • Niv, E.1    Bomstein, Y.2    Bernheim, J.3    Lishner, M.4
  • 88
    • 0036569940 scopus 로고    scopus 로고
    • Mutations at coding repeat sequences in mismatch repair-deficient human cancers: Toward a new concept of target genes for instability
    • Duval A, Hamelin R. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 2002; 62: 2447-54.
    • (2002) Cancer Res , vol.62 , pp. 2447-2454
    • Duval, A.1    Hamelin, R.2
  • 89
    • 0038671797 scopus 로고    scopus 로고
    • Pathogenesis of DNA repair-deficient cancers: A statistical meta-analysis of putative Real Common Target genes
    • Woerner SM, Benner A, Sutter C, Schiller M, Yuan YP, Keller G, et al. Pathogenesis of DNA repair-deficient cancers: a statistical meta-analysis of putative Real Common Target genes. Oncogene 2003; 22: 2226-35.
    • (2003) Oncogene , vol.22 , pp. 2226-2235
    • Woerner, S.M.1    Benner, A.2    Sutter, C.3    Schiller, M.4    Yuan, Y.P.5    Keller, G.6
  • 90
    • 0035879041 scopus 로고    scopus 로고
    • Red meat, family history, and increased risk of gastric cancer with microsatellite instability
    • Palli D, Russo A, Ottini L, Masala G, Saieva C, Amorosi A, et al. Red meat, family history, and increased risk of gastric cancer with microsatellite instability. Cancer Res 2001; 61: 5415-9.
    • (2001) Cancer Res , vol.61 , pp. 5415-5419
    • Palli, D.1    Russo, A.2    Ottini, L.3    Masala, G.4    Saieva, C.5    Amorosi, A.6
  • 91
    • 22644434527 scopus 로고    scopus 로고
    • Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer
    • Nan HM, Song YJ, Yun HY, Park JS, Kim H. Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer. World J Gastroenterol 2005; 25: 3834-41.
    • (2005) World J Gastroenterol , vol.25 , pp. 3834-3841
    • Nan, H.M.1    Song, Y.J.2    Yun, H.Y.3    Park, J.S.4    Kim, H.5
  • 92
    • 66149108352 scopus 로고    scopus 로고
    • Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression
    • Oliveira C, Sousa S, Pinheiro H, Karam R, Bordeira-Carrico R, Senz J, et al. Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. Gastroenterology 2009; 136: 2137-48.
    • (2009) Gastroenterology , vol.136 , pp. 2137-2148
    • Oliveira, C.1    Sousa, S.2    Pinheiro, H.3    Karam, R.4    Bordeira-Carrico, R.5    Senz, J.6
  • 94
    • 23444445704 scopus 로고    scopus 로고
    • Microsatellite instability and gastric non invasive neoplasia in a high risk population in Cesena, Italy
    • Rugge M, Bersani G, Bertorelle R, Penelli G, Russo VM, Farinati F, et al. Microsatellite instability and gastric non invasive neoplasia in a high risk population in Cesena, Italy. J Clin Pathol 2005; 58: 805-10.
    • (2005) J Clin Pathol , vol.58 , pp. 805-810
    • Rugge, M.1    Bersani, G.2    Bertorelle, R.3    Penelli, G.4    Russo, V.M.5    Farinati, F.6
  • 95
    • 0036329324 scopus 로고    scopus 로고
    • Microsatellite instability in Japanese Vs European American patients with gastric cancer
    • Theuer CP, Campbell BS, Peel DJ, Lin F, Carpenter P, Ziogas A, et al. Microsatellite instability in Japanese Vs European American patients with gastric cancer. Arch Surg 2002; 137: 960-6.
    • (2002) Arch Surg , vol.137 , pp. 960-966
    • Theuer, C.P.1    Campbell, B.S.2    Peel, D.J.3    Lin, F.4    Carpenter, P.5    Ziogas, A.6
  • 96
    • 68949205565 scopus 로고    scopus 로고
    • Chemosensitivity and survival in gastric cancer patients with microsatellite instability
    • Oki E, Kakeji Y, Zhao Y, Yoshida R, Ando K, Mascuda T, et al. Chemosensitivity and survival in gastric cancer patients with microsatellite instability. Ann Surg Oncol 2009; 16: 2510-5.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2510-2515
    • Oki, E.1    Kakeji, Y.2    Zhao, Y.3    Yoshida, R.4    Ando, K.5    Mascuda, T.6
  • 97
    • 73349127495 scopus 로고    scopus 로고
    • Allelic imbalance at p53 and microsatellite instability are predictive markers for resistance to chemotherapy in gastric carcinoma
    • Yashiro M, Inoue T, Nishioka N, Matsuoka T, Boland CR, Hirakawa K. Allelic imbalance at p53 and microsatellite instability are predictive markers for resistance to chemotherapy in gastric carcinoma. Ann Surg Oncol 2009; 16: 2926-35.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2926-2935
    • Yashiro, M.1    Inoue, T.2    Nishioka, N.3    Matsuoka, T.4    Boland, C.R.5    Hirakawa, K.6
  • 98
    • 0033779384 scopus 로고    scopus 로고
    • Epstein-Barr Virus and gastric carcinoma
    • Takada K. Epstein-Barr Virus and gastric carcinoma. Mol Pathol 2000; 53: 255-61.
    • (2000) Mol Pathol , vol.53 , pp. 255-261
    • Takada, K.1
  • 99
    • 33744789155 scopus 로고    scopus 로고
    • CpG island metylation status in gastric carcinoma with and without infection of Epstein Barr Virus
    • Chang MS, Uozaki H, Chong JM, Ushiku T, Sakuma K, Ishikawa S, et al. CpG island metylation status in gastric carcinoma with and without infection of Epstein Barr Virus. Clin Cancer Res 2006; 12: 2995-3002.
    • (2006) Clin Cancer Res , vol.12 , pp. 2995-3002
    • Chang, M.S.1    Uozaki, H.2    Chong, J.M.3    Ushiku, T.4    Sakuma, K.5    Ishikawa, S.6
  • 100
    • 0036286666 scopus 로고    scopus 로고
    • Epstein Barr Virus, p53 protein and microsatellite instability in the adenoma carcinoma sequence of the stomach
    • Chang MS, Kim HS, Kim CW, Kim YI, Lee BL, Kim WH. Epstein Barr Virus, p53 protein and microsatellite instability in the adenoma carcinoma sequence of the stomach. Hum Pathol 2002; 33: 415-20.
    • (2002) Hum Pathol , vol.33 , pp. 415-420
    • Chang, M.S.1    Kim, H.S.2    Kim, C.W.3    Kim, Y.I.4    Lee, B.L.5    Kim, W.H.6
  • 101
    • 0017169969 scopus 로고
    • Gastric carcinoma with lymphoid stroma: Its morphologic characteristic and prognostic correlations
    • Watanabe H, Enjoji M, Imai T. Gastric carcinoma with lymphoid stroma: its morphologic characteristic and prognostic correlations. Cancer 1976; 38: 232-43.
    • (1976) Cancer , vol.38 , pp. 232-243
    • Watanabe, H.1    Enjoji, M.2    Imai, T.3
  • 102
    • 33644827779 scopus 로고    scopus 로고
    • Intratumour T cells, their activation status and survival in gastric carcinomas characterised for microsatellite instability and Epstein Barr Virus infection
    • Chiaravalli AM, Feltri M, Bertolini V, Bagnoli E, Furlan D, Cerutti R, et al. Intratumour T cells, their activation status and survival in gastric carcinomas characterised for microsatellite instability and Epstein Barr Virus infection. Virchows Arch 2006; 448: 344-53.
    • (2006) Virchows Arch , vol.448 , pp. 344-353
    • Chiaravalli, A.M.1    Feltri, M.2    Bertolini, V.3    Bagnoli, E.4    Furlan, D.5    Cerutti, R.6
  • 103
    • 0038446928 scopus 로고    scopus 로고
    • Lymphocyte rich gastric cancer: Associations with Epstein Barr Virus, microsatellite instability, histology and survival
    • Grogg KL, Lohse CM, Pankratz VS, Halling KC, Smyrk TC. Lymphocyte rich gastric cancer: associations with Epstein Barr Virus, microsatellite instability, histology and survival. Mod Pathol 2003; 16: 641-51.
    • (2003) Mod Pathol , vol.16 , pp. 641-651
    • Grogg, K.L.1    Lohse, C.M.2    Pankratz, V.S.3    Halling, K.C.4    Smyrk, T.C.5
  • 104
    • 0033591290 scopus 로고    scopus 로고
    • Rappuoli R. Helicobacter pylori virulence and genetic geography
    • Covacci A, Telford JL, Giudice GD, Parsonnet J, Rappuoli R. Helicobacter pylori virulence and genetic geography. Science 1999; 284: 1328-33.
    • (1999) Science , vol.284 , pp. 1328-1333
    • Covacci, A.1    Telford, J.L.2    Giudice, G.D.3    Parsonnet, J.4
  • 105
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinoma
    • Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinoma. Nat Rev Cancer 2002; 2: 28-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek Jr., R.M.1    Blaser, M.J.2
  • 108
    • 33745905305 scopus 로고    scopus 로고
    • Demonstration and characterization of mutations induced by Helicobacter pylori organisms in gastric epithelial cells
    • Yao Y, Tao H, Park DI, Sepulveda JL, Sepulveda AR. Demonstration and characterization of mutations induced by Helicobacter pylori organisms in gastric epithelial cells. Helicobacter 2006; 11: 272-86.
    • (2006) Helicobacter , vol.11 , pp. 272-286
    • Yao, Y.1    Tao, H.2    Park, D.I.3    Sepulveda, J.L.4    Sepulveda, A.R.5
  • 109
    • 65649154690 scopus 로고    scopus 로고
    • Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in Gastric cells
    • Machado AM, Figueiredo C, Touati E, Máximo V, Sousa S, Michel V, et al. Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in Gastric cells. Clin Cancer Res 2009; 15: 2995-3002.
    • (2009) Clin Cancer Res , vol.15 , pp. 2995-3002
    • Machado, A.M.1    Figueiredo, C.2    Touati, E.3    Máximo, V.4    Sousa, S.5    Michel, V.6
  • 110
    • 77953718630 scopus 로고    scopus 로고
    • Helicobacter pylori infection generates genetic instability in gastric cells
    • Machado AM, Figueiredo C, Seruca R, Rasmussen LJ. Helicobacter pylori infection generates genetic instability in gastric cells. Biochim Biophys Acta 2010; 1806: 58-65.
    • (2010) Biochim Biophys Acta , vol.1806 , pp. 58-65
    • Machado, A.M.1    Figueiredo, C.2    Seruca, R.3    Rasmussen, L.J.4
  • 111
    • 39049175387 scopus 로고    scopus 로고
    • Analysis of the differences in structural chromosomal aberrations of the gastric mucosa between H. pylori positive and negative gastric cancer patients: Involvement of H. pylori in the onset of gastric cancer and examination of the mechanism in gastric carcinogenesis following H. pylori eradication
    • Ohara T, Kasanuki J, Ohara H, Kanoh Y, Suzuki H, Hashimoto H, et al. Analysis of the differences in structural chromosomal aberrations of the gastric mucosa between H. pylori positive and negative gastric cancer patients: involvement of H. pylori in the onset of gastric cancer and examination of the mechanism in gastric carcinogenesis following H. pylori eradication. Oncol Rep 2006; 16: 1333-42.
    • (2006) Oncol Rep , vol.16 , pp. 1333-1342
    • Ohara, T.1    Kasanuki, J.2    Ohara, H.3    Kanoh, Y.4    Suzuki, H.5    Hashimoto, H.6
  • 112
    • 0031473168 scopus 로고    scopus 로고
    • Mitochondrial D-loop 3' (CA)n repeat polymorphism: Optimization of analysis and population data
    • Szibor R, Michael M, Spitsyn VA, Plate I, Ginter EK, Krause D. Mitochondrial D-loop 3' (CA)n repeat polymorphism: optimization of analysis and population data. Electrophoresis 1997; 18: 2857-60.
    • (1997) Electrophoresis , vol.18 , pp. 2857-2860
    • Szibor, R.1    Michael, M.2    Spitsyn, V.A.3    Plate, I.4    Ginter, E.K.5    Krause, D.6
  • 113
    • 0029017083 scopus 로고
    • Length heteroplasmy in the first hypervariable segment of the human mtDNA control region
    • Bendall KE, Sykes BC. Length heteroplasmy in the first hypervariable segment of the human mtDNA control region. Am J Hum Genet 1995; 57: 248-56.
    • (1995) Am J Hum Genet , vol.57 , pp. 248-256
    • Bendall, K.E.1    Sykes, B.C.2
  • 115
    • 0032729633 scopus 로고    scopus 로고
    • Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
    • Habano W, Sugai T, Yoshida T, Nakamura S. Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int J Cancer 1999; 83: 625-9.
    • (1999) Int J Cancer , vol.83 , pp. 625-629
    • Habano, W.1    Sugai, T.2    Yoshida, T.3    Nakamura, S.4
  • 116
    • 22144472961 scopus 로고    scopus 로고
    • Mutation in D-Loop region of mitochondrial DNA in gastric cancer and its significance
    • Zhao YB, Yang HY, Zhang XW, Chen GY. Mutation in D-Loop region of mitochondrial DNA in gastric cancer and its significance. World J Gastroenterol 2005; 11: 3304-6.
    • (2005) World J Gastroenterol , vol.11 , pp. 3304-3306
    • Zhao, Y.B.1    Yang, H.Y.2    Zhang, X.W.3    Chen, G.Y.4
  • 117
    • 0036277609 scopus 로고    scopus 로고
    • Helicobacter pylori-induced oxidative stress and DNA damage in a primary culture of human gastric mucosal cells
    • Bagchi D, McGinn TR, Ye X, Bagchi M, Krohn RL, Chatterjee A, et al. Helicobacter pylori-induced oxidative stress and DNA damage in a primary culture of human gastric mucosal cells. Dig Dis Sci 2002; 47: 1405-12.
    • (2002) Dig Dis Sci , vol.47 , pp. 1405-1412
    • Bagchi, D.1    McGinn, T.R.2    Ye, X.3    Bagchi, M.4    Krohn, R.L.5    Chatterjee, A.6
  • 118
    • 0034854114 scopus 로고    scopus 로고
    • Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma
    • Maximo V, Soares P, Seruca R, Rocha AS, Castro P, Sobrinho- Simoes M. Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma. Genes Chromosomes Cancer 2001; 32: 136-43.
    • (2001) Genes Chromosomes Cancer , vol.32 , pp. 136-143
    • Maximo, V.1    Soares, P.2    Seruca, R.3    Rocha, A.S.4    Castro, P.5    Sobrinho-Simoes, M.6
  • 120
    • 77952242686 scopus 로고    scopus 로고
    • Mitochondrial microsatellite instability in gastric cancer and gastric epithelial dysplasia as a precancerous lesion
    • Jeong CW, Lee JH, Sohn SS, Ryu SW, Kim DK. Mitochondrial microsatellite instability in gastric cancer and gastric epithelial dysplasia as a precancerous lesion. Cancer Epidemiol 2010; 34: 323-7.
    • (2010) Cancer Epidemiol , vol.34 , pp. 323-327
    • Jeong, C.W.1    Lee, J.H.2    Sohn, S.S.3    Ryu, S.W.4    Kim, D.K.5
  • 121
    • 34347405282 scopus 로고    scopus 로고
    • Association between Helicobacter pylori-related peptic ulcer tissue and somatic mitochondrial DNA mutations
    • Lee S, Shin MG, Jo WH, Kim MJ, Kim HR, Park DH, et al. Association between Helicobacter pylori-related peptic ulcer tissue and somatic mitochondrial DNA mutations. Clin Chem 2007; 53: 1390-2.
    • (2007) Clin Chem , vol.53 , pp. 1390-1392
    • Lee, S.1    Shin, M.G.2    Jo, W.H.3    Kim, M.J.4    Kim, H.R.5    Park, D.H.6
  • 123
    • 0038527233 scopus 로고    scopus 로고
    • Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia
    • Waki T, Tamura G, Sato M, Terashima M, Nishizuka S, Motoyama T. Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia. Cancer Sci 2003; 94: 360-4.
    • (2003) Cancer Sci , vol.94 , pp. 360-364
    • Waki, T.1    Tamura, G.2    Sato, M.3    Terashima, M.4    Nishizuka, S.5    Motoyama, T.6
  • 124
    • 1842455990 scopus 로고    scopus 로고
    • Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma
    • Oshimo Y, Oue N, Mitani Y, Nakayama H, Kitadai Y, Yoshida K, et al. Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma. Pathobiology 2004; 71: 137-43.
    • (2004) Pathobiology , vol.71 , pp. 137-143
    • Oshimo, Y.1    Oue, N.2    Mitani, Y.3    Nakayama, H.4    Kitadai, Y.5    Yoshida, K.6
  • 125
    • 0031746725 scopus 로고    scopus 로고
    • Prognostic value and clinicopathologicalprofile of microsatellite instability in gastric cancer
    • Wirtz HC, Muller W, Noguchi T, Scheven M, Ruschoff J, Hommel G, et al. Prognostic value and clinicopathologicalprofile of microsatellite instability in gastric cancer. Clin Cancer Res 1998; 4: 1749-54.
    • (1998) Clin Cancer Res , vol.4 , pp. 1749-1754
    • Wirtz, H.C.1    Muller, W.2    Noguchi, T.3    Scheven, M.4    Ruschoff, J.5    Hommel, G.6
  • 127
    • 35748941302 scopus 로고    scopus 로고
    • Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study
    • Gargano G, Calcara D, Corsale S, Agnese V, Intrivici C, Fulfaro F, et al. Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. Ann Oncol 2007; 18: vi103-9.
    • (2007) Ann Oncol , vol.18
    • Gargano, G.1    Calcara, D.2    Corsale, S.3    Agnese, V.4    Intrivici, C.5    Fulfaro, F.6


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