Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients

Oncology Reports

Volumn 16, Issue 1, 2006, Pages 11-15

  Sasao, Shogo ^a   Hiyama, Toru ^c   Tanaka, Shinji ^b   Yoshihara, Masaharu ^c   Yasui, Wataru ^a   Chayama, Kazuaki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

B raf; Gastric cancer; hMLH3; K ras; Microsatellite instability

Indexed keywords

B RAF KINASE; BRAF PROTEIN, HUMAN; CARRIER PROTEIN; MICROSATELLITE DNA; MLH3 PROTEIN, HUMAN;

ADULT; AGE; ARTICLE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; MIDDLE AGED; MUTATION; ONCOGENE RAS; PATHOLOGY; SEX DIFFERENCE; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH TUMOR;

ADULT; AGE FACTORS; CARRIER PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS B-RAF; SEX FACTORS; STOMACH NEOPLASMS;

EID: 33750716501     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.16.1.11     Document Type: Article

References (23)

1. Parkin DM, Pisani P and Ferlay J: Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 54: 594-606, 1993. (Pubitemid 23188190)
2. Meyers WC, Damiano RJ Jr, Rotolo FS and Postlethwait RW: Adenocarcinoma of the stomach. Changing patterns over the last 4 decades. Ann Surg 205: 1-8, 1987. (Pubitemid 17010670)
3. Miyoshi E, Haruma K, Hiyama T, Tanaka S, Yoshihara M, Shimamoto F and Chayama K: Microsatellite instability is a genetic marker for the development of multiple gastric cancers. Int J Cancer 95: 350-353, 2001. (Pubitemid 33015103)
4. Hiyama T, Haruma K, Kitadai Y, Masuda H, Miyamoto M, Tanaka S, Yoshihara M, Shimamoto F and Chayama K: K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer. Int J Cancer 97: 562-566, 2002. (Pubitemid 34087791)
5. Hiyama T, Tanaka S, Yoshihara M, Sasao S, Kose K, Shima H, Tuncel H, Ueno Y, Ito M, Kitadai Y, Yasui W, Haruma K and Chayama K: Chromosomal and microsatellite instability in sporadic gastric cancer. J Gastroenterol Hepatol 19: 756-760, 2004. (Pubitemid 38981396)
6. Hayden JD, Cawkwell L, Sue-Ling H, Johnston D, Dixon MF, Quirke P and Martin IG: Assessment of microsatellite alterations in young patients with gastric adenocarcinoma. Cancer 79: 684-687, 1997. (Pubitemid 27076333)
7. Mori M, Sugimachi K, Ohiwa T, Okamura T, Tamura S and Inokuchi K: Early gastric carcinoma in Japanese patients under 30 years of age. Br J Surg 72: 289-291, 1985. (Pubitemid 15090959)
8. Nakamura T, Yao T, Niho Y and Tsuneyoshi M: A clinicopathological study in young patients with gastric carcinoma. J Surg Oncol 71: 214-219, 1999. (Pubitemid 29388016)
9. Lauren P: The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. APMIS 64: 31-49, 1965.
10. Miyamoto M, Haruma K, Hiyama T, Kamada T, Masuda H, Shimamoto F, Inoue K and Chayama K: High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma. Virchows Arch 440: 376-380, 2002. (Pubitemid 34328068)
11. Hiyama T, Tanaka S, Kitadai Y, Ito M, Sumii M, Yoshihara M, Shimamoto F, Haruma K and Chayama K: p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis. Int J Cancer 100: 304-308, 2002. (Pubitemid 34728988)
12. Akiyama Y, Nagasaki H, Nakajima T, Sakai H, Nomizu T and Yuasa Y: Infrequent frameshift mutations in the simple repeat sequences of hMLH3 in hereditary nonpolyposis colorectal cancers. Jpn J Clin Oncol 31: 61-64, 2001. (Pubitemid 32293965)
13. Wu M, Semba S, Oue N, Ikehara N, Yasui W and Yokozaki H: BRAF/K-ras mutation, microsatellite instability, and promoter hypermethylation of hMLH1/MGMT in human gastric carcinomas. Gastric Cancer 7: 246-253, 2004.
14. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN and Srivastava S: A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257, 1998.
15. Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G and Hamelin R: BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 57: 300-303, 1997. (Pubitemid 27036610)
16. Semba S, Yokozaki H, Yasui W and Tahara E: Frequent microsatellite instability and loss of heterozygosity in the region including BRCA1 (17q21) in young patients with gastric cancer. Int J Oncol 12: 1245-1251, 1998. (Pubitemid 28239931)
17. Lim S, Lee HS, Kim HS, Kim YI and Kim WH: Alteration of E-cadherin-mediated adhesion protein is common, but microsatellite instability is uncommon in young age gastric cancers. Histopathology 42: 128-136, 2003. (Pubitemid 36237844)
18. Miyamoto M, Haruma K, Yoshihara M, Sumioka M, Nishisaka T, Tanaka S, Inoue K and Chayama K: Five cases of nodular gastritis and gastric cancer : a possible association between nodular gastritis and gastric cancer. Dig Liver Dis 34: 819-820, 2002.
19. Kiaris H and Spandidos DA: Mutations of ras genes in human tumours (Review). Int J Oncol 7: 413-421, 1995.
20. Ellis CA and Clark G: The importance of being K-Ras. Cell Signal 12: 425-434, 2000.
21. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR and Futreal PA: Mutations of the BRAF gene in human cancer. Nature 417: 949-954, 2002. (Pubitemid 34716871)
22. Lee SH, Lee JW, Soung YH, Kim HS, Park WS, Kim SY, Lee JH, Park JY, Cho YG, Kim CJ, Nam SW, Kim SH, Lee JY and Yoo NJ: BRAF and KRAS mutations in stomach cancer. Oncogene 22: 6942-6945, 2003. (Pubitemid 37386695)
23. Oliveira C, Pinto M, Duval A, Brennetot C, Domingo E, Espin E, Armengol M, Hamelin R, Seruca R and Schwartz S Jr: BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency. Oncogene 22: 9192-9196, 2003. (Pubitemid 38067995)