Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly

Geriatrics and Gerontology International

Volumn 10, Issue SUPPL. 1, 2010, Pages

  Arai, Tomio ^a   Kasahara, Ichiro ^a   Sawabe, Motoji ^a   Honma, Naoko ^b   Aida, Junko ^b   Tabubo, Kaiyo ^b  

^a Tokyo Metropolitan Institute of Gerontology   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Aging; Carcinoma; HMLH1 gene; Hypermethylation; Microsatellite instability

Indexed keywords

GENOMIC DNA; PROTEIN MLH1; TELOMERASE REVERSE TRANSCRIPTASE; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADENOCARCINOMA; AGING; CARCINOGENESIS; CELL DIFFERENTIATION; CELL INFILTRATION; CHROMOSOMAL INSTABILITY; COLORECTAL CARCINOMA; CROHN DISEASE; DNA DAMAGE; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENETIC ASSOCIATION; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LARGE INTESTINE; LYMPH NODE METASTASIS; MALIGNANT NEOPLASTIC DISEASE; MICROSATELLITE INSTABILITY; MOLECULAR BIOLOGY; MUCINOUS CARCINOMA; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; REVIEW; SENESCENCE; STOMACH; STOMACH CARCINOMA; TELOMERE; AGED; CHEMISTRY; COLLOID CARCINOMA; COLORECTAL TUMOR; DNA REPAIR; GENETIC EPIGENESIS; GENETICS; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; STOMACH TUMOR;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; ADENOCARCINOMA, MUCINOUS; AGED; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; EPIGENESIS, GENETIC; HUMANS; MICROSATELLITE INSTABILITY; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS;

EID: 77954672135     PISSN: 14441586     EISSN: 14470594     Source Type: Journal    
DOI: 10.1111/j.1447-0594.2010.00590.x     Document Type: Review

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