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Volumn 4, Issue 2, 2012, Pages 177-186

L-tetrahydropalamatine: A potential new medication for the treatment of cocaine addiction

Author keywords

An intense; overwhelming and often uncontrollable desire to use a drug

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DRUGS USED IN THE TREATMENT OF ADDICTION; HERBACEOUS AGENT; LEVO TETRAHYDROPALMATINE; UNCLASSIFIED DRUG;

EID: 84863011788     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.11.166     Document Type: Review
Times cited : (84)

References (61)
  • 1
    • 33747059006 scopus 로고    scopus 로고
    • Office of National Drug Control Policy 2004 Washington, DC: Executive Office of the President (Publication 207303).
    • Office of National Drug Control Policy (2004). The Economic Costs of Drug Abuse in the United States, 1992-2002. Washington, DC: Executive Office of the President (Publication No. 207303).
    • Economic Costs of Drug Abuse in the United States 1992-2002
  • 3
    • 43149109280 scopus 로고    scopus 로고
    • Recent development in studies of tetrahydroprotoberberines: Mechanism in antinociception and drug addiction
    • DOI 10.1007/s10571-007-9179-4
    • Chu H, Jin G, Friedman E, Zhen X. Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction. Cell. Mol. Neurobiol. 28, 491-499 (2008). (Pubitemid 351637559)
    • (2008) Cellular and Molecular Neurobiology , vol.28 , Issue.4 , pp. 491-499
    • Chu, H.1    Jin, G.2    Friedman, E.3    Zhen, X.4
  • 5
    • 0019994823 scopus 로고
    • Garattini S d-l-tetrahydropalmatine as monoamine depletory
    • Liu GQ, Algeri S, Garattini S. d-l-tetrahydropalmatine as monoamine depletor. Arch. Int. Pharm. Therap. 258, 39-50 (1982).
    • (1982) Arch. Int. Pharm. Therap. , vol.258 , pp. 39-50
    • Liu, G.Q.1    Algeri, S.2
  • 7
    • 31344478233 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometry for the identification of L-tetrahydropalmatine metabolites in Penicillium janthinellum and rats
    • DOI 10.1002/bmc.534
    • Li L, Ye M, Bi K, Guo D. Liquid chromatography-tandem mass spectrometry for the identification of l-tetrahydropalmatine metabolites in Penicillium janthinellum and rats. Biomed. Chromatogr. 20, 95-100 (2006). (Pubitemid 43141411)
    • (2006) Biomedical Chromatography , vol.20 , Issue.1 , pp. 95-100
    • Li, L.1    Ye, M.2    Bi, K.3    Guo, D.4
  • 8
    • 0033064657 scopus 로고    scopus 로고
    • Tetrahydropalmatine poisoning: Diagnoses of nine adult overdoses based on toxicology screens by HPLC with diode-array detection and gas chromatography-mass spectrometry
    • Lai CK, Chan AY. Tetrahydropalmatine poisoning: diagnoses of nine adult overdoses based on toxicology screens by HPLC with diode-array detection and gas chromatography-mass spectrometry. Clin. Chem. 45, 229-236 (1999). (Pubitemid 29079121)
    • (1999) Clinical Chemistry , vol.45 , Issue.2 , pp. 229-236
    • Lai, C.-K.1    Chan, A.Y.-W.2
  • 9
    • 53249088134 scopus 로고    scopus 로고
    • Isoquinoline alkaloids isolated from corydalis yanhusuo and their binding affinities at the dopamine d1 receptor
    • Ma ZZ, Xu W, Jensen NH, Roth BL, Liu-Chen LY, Lee DY. Isoquinoline alkaloids isolated from Corydalis Yanhusuo and their binding affinities at the dopamine D1 receptor. Molecules 13, 2303-2312 (2008).
    • (2008) Molecules , vol.13 , pp. 2303-2312
    • Ma, Z.Z.1    Xu, W.2    Jensen, N.H.3    Roth, B.L.4    Liu-Chen, L.Y.5    Lee, D.Y.6
  • 10
    • 0023350755 scopus 로고
    • Progress in studies of the pharmacology of l-tetrahydropalmatine and l-stepholidine
    • Jin GZ. Progress in studies of the pharmacology of l-tetrahydropalmatine and l-stepholidine. Acta Pharm. Sinica 22, 472-480 (1987).
    • (1987) Acta Pharm. Sinica. , vol.22 , pp. 472-480
    • Jin, G.Z.1
  • 11
    • 0020576369 scopus 로고
    • Relevance of sedative-tranquilizing effect of l-tetrahydropalmatine to brain monoaminergic neurotransmitters
    • Jin GZ, Xu J, Zhang FT, Yu LP, Li JH, Wang XL. Relevance of the sedative-tranquilizing effect of l-tetrahydropalmatine to brain monoaminergic neurotransmitters. Acta Pharm. Sinica 4, 4-10 (1983). (Pubitemid 13045107)
    • (1983) Acta Pharmacologica Sinica , vol.4 , Issue.1 , pp. 4-10
    • Jin, G.Z.1    Xu, J.2    Zhang, F.T.3
  • 13
    • 34249869292 scopus 로고    scopus 로고
    • Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats
    • DOI 10.1007/s00213-007-0754-7
    • Mantsch JR, Li SJ, Risinger R, Awad S, Katz E, Baker DA, Yang Z. Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats. Psychopharmacology 192, 581-591 (2007). (Pubitemid 46870752)
    • (2007) Psychopharmacology , vol.192 , Issue.4 , pp. 581-591
    • Mantsch, J.R.1    Li, S.-J.2    Risinger, R.3    Awad, S.4    Katz, E.5    Baker, D.A.6    Yang, Z.7
  • 14
    • 33646358216 scopus 로고    scopus 로고
    • Brain pharmacokinetics and tissue distribution of tetrahydropalmatine enantiomers in rats after oral administration of the racemate
    • Hong Z, Fan G, Le J, Chai Y, Yin X, Wu Y. Brain pharmacokinetics and tissue distribution of tetrahydropalmatine enantiomers in rats after oral administration of the racemate. Biopharm. Drug Dispos. 27, 111-117 (2006).
    • (2006) Biopharm. Drug Dispos. , vol.27 , pp. 111-117
    • Hong, Z.1    Fan, G.2    Le J Chai, Y.3    Yin, X.4    Wu, Y.5
  • 16
    • 0022515821 scopus 로고
    • Effect of l-tetrahydropalmatine on dopamine release and metabolism in the rat striatum
    • Marcenac F, Jin GZ, Gonon F. Effect of l-tetrahydropalmatine on dopamine release and metabolism in the rat striatum. Psychopharmacology 89, 89-93 (1986). (Pubitemid 16062969)
    • (1986) Psychopharmacology , vol.89 , Issue.1 , pp. 89-93
    • Marcenac, F.1    Jin, G.Z.2    Gonon, F.3
  • 18
    • 0030308136 scopus 로고    scopus 로고
    • 1-adrenoceptor
    • Lu ZZ, Wei X, Jin GZ, Han QD. Antagonistic effect of tetrahydroproberberine homologues on a 1-adrenoceptor. Acta Pharm. Sinica 31, 652-656 (1996). (Pubitemid 126436283)
    • (1996) Yaoxue Xuebao , vol.31 , Issue.9 , pp. 652-656
    • Lu, Z.Z.1    Wei, X.2    Jin, G.Z.3    Han, Q.D.4
  • 19
    • 0038291588 scopus 로고    scopus 로고
    • A binding site
    • DOI 10.1055/s-2003-38869
    • Halbsguth C, Meissner O, Haberlein H. Positive cooperation of protoberberine type 2 alkaloids from Corydalis cava on the GABA(A) binding site. Plant. Med. 69, 305-309 (2003). (Pubitemid 36577994)
    • (2003) Planta Medica , vol.69 , Issue.4 , pp. 305-309
    • Halbsguth, C.1    Meissner, O.2    Haberlein, H.3
  • 20
    • 19444366055 scopus 로고    scopus 로고
    • Cocaine-induced alterations in dopamine receptor signaling: Implications for reinforcement and reinstatement
    • DOI 10.1016/j.pharmthera.2004.12.004, PII S0163725805000197
    • Anderson SM, Pierce RC. Cocaine-induced alterations in dopamine receptor signaling: implications for reinforcement and reinstatement. Pharm. Therap. 106, 389-403 (2005). (Pubitemid 40731541)
    • (2005) Pharmacology and Therapeutics , vol.106 , Issue.3 , pp. 389-403
    • Anderson, S.M.1    Pierce, R.C.2
  • 21
    • 4644261142 scopus 로고    scopus 로고
    • Regulation of drug-taking and -seeking behaviors by neuroadaptations in the mesolimbic dopamine system
    • DOI 10.1016/j.neuropharm.2004.07.005, PII S0028390804001972
    • Self DW. Regulation of drug-taking and -seeking behaviors by neuroadaptations in the mesolimbic dopamine system. Neuropharmacology 47(Suppl. 1), 242-255 (2004). (Pubitemid 39298268)
    • (2004) Neuropharmacology , vol.47 , Issue.SUPPL. 1 , pp. 242-255
    • Self, D.W.1
  • 22
    • 4644358601 scopus 로고    scopus 로고
    • The addicted human brain viewed in the light of imaging studies: Brain circuits and treatment strategies
    • DOI 10.1016/j.neuropharm.2004.07.019, PII S0028390804002163
    • Volkow ND, Fowler JS, Wang GJ. The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies. Neuropharmacology 47(Suppl. 1), 3-13 (2004). (Pubitemid 39298248)
    • (2004) Neuropharmacology , vol.47 , Issue.SUPPL. 1 , pp. 3-13
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.-J.3
  • 23
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar MJ, Ritz MC, Boja JW. The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci. 14, 299-302 (1991).
    • (1991) Trends Neurosci. , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 24
    • 0036392443 scopus 로고    scopus 로고
    • Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development
    • Platt DM, Rowlett JK, Spealman RD. Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development. Psychopharmacology 163, 265-282 (2002).
    • (2002) Psychopharmacology , vol.163 , pp. 265-282
    • Platt, D.M.1    Rowlett, J.K.2    Spealman, R.D.3
  • 25
    • 34948901336 scopus 로고    scopus 로고
    • Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: Experiments with self-administration and brain-stimulation reward in rats
    • DOI 10.1016/j.neuropharm.2007.08.004, PII S002839080700250X
    • Xi ZX, Yang Z, Li SJ et al. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropharmacology 53, 771-782 (2007). (Pubitemid 47532146)
    • (2007) Neuropharmacology , vol.53 , Issue.6 , pp. 771-782
    • Xi, Z.-X.1    Yang, Z.2    Li, S.-J.3    Li, X.4    Dillon, C.5    Peng, X.-Q.6    Spiller, K.7    Gardner, E.L.8
  • 26
    • 77957811262 scopus 로고    scopus 로고
    • Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats
    • Mantsch JR, Wisniewski S, Vranjkovic O et al. Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats. Pharm. Biochem. Behav. 97, 310-316 (2010).
    • (2010) Pharm. Biochem. Behav. , vol.97 , pp. 310-316
    • Mantsch, J.R.1    Wisniewski, S.2    Vranjkovic, O.3
  • 27
    • 0033970304 scopus 로고    scopus 로고
    • Dopamine receptor partial agonists could address the duality of cocaine craving
    • DOI 10.1016/S0165-6147(99)01422-4, PII S0165614799014200
    • Childress AR, O'Brien CP. Dopamine receptor partial agonists could address the duality of cocaine craving. Trends Pharm. Sci. 21, 6-9 (2000). (Pubitemid 30102182)
    • (2000) Trends in Pharmacological Sciences , vol.21 , Issue.1 , pp. 6-9
    • Childress, A.R.1    O'Brien, C.P.2
  • 28
    • 0028028365 scopus 로고
    • Dopamine receptor agonists, partial agonists and psychostimulant addiction
    • DOI 10.1016/0165-6147(94)90158-9
    • Pulvirenti L, Koob GF. Dopamine receptor agonists, partial agonists and psychostimulant addiction. Trends Pharm. Sci. 15, 374-379 (1994). (Pubitemid 24325709)
    • (1994) Trends in Pharmacological Sciences , vol.15 , Issue.10 , pp. 374-379
    • Pulvirenti, L.1    Koob, G.F.2
  • 30
    • 3242755117 scopus 로고    scopus 로고
    • Agents in development for the management of cocaine abuse
    • DOI 10.2165/00003495-200464140-00004
    • Gorelick DA, Gardner EL, Xi ZX. Agents in development for the management of cocaine abuse. Drugs 64, 1547-1573 (2004). (Pubitemid 38981839)
    • (2004) Drugs , vol.64 , Issue.14 , pp. 1547-1573
    • Gorelick, D.A.1    Gardner, E.L.2    Xi, Z.-X.3
  • 31
    • 23344447151 scopus 로고    scopus 로고
    • Medication development for addictive disorders: The state of the science
    • DOI 10.1176/appi.ajp.162.8.1432
    • Vocci FJ, Acri J, Elkashef A. Medication development for addictive disorders: the state of the science. Am. J. Psychiatry 162, 1432-1440 (2005). (Pubitemid 41105557)
    • (2005) American Journal of Psychiatry , vol.162 , Issue.8 , pp. 1432-1440
    • Vocci, F.J.1    Acri, J.2    Elkashef, A.3
  • 32
    • 0036162683 scopus 로고    scopus 로고
    • (-)-Stepholidine: A potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions
    • DOI 10.1016/S0165-6147(00)01929-5, PII S0165614700019295
    • Jin GZ, Zhu ZT, Fu Y. (-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions. Trends Pharm. Sci. 23, 4-7 (2002). (Pubitemid 34135965)
    • (2002) Trends in Pharmacological Sciences , vol.23 , Issue.1 , pp. 4-7
    • Jin, G.-Z.1    Zhu, Z.-T.2    Fu, Y.3
  • 33
    • 0034613214 scopus 로고    scopus 로고
    • Differential effects of stimulants on monoaminergic transporters: Pharmacological consequences and implications for neurotoxicity
    • Fleckenstein AE, Gibb JW, Hanson GR. Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur. J. Pharmacology 406, 1-13 (2000).
    • (2000) Eur. J. Pharmacology , vol.406 , pp. 1-13
    • Fleckenstein, A.E.1    Gibb, J.W.2    Hanson, G.R.3
  • 34
    • 77953181780 scopus 로고    scopus 로고
    • Behavioral evidence for the significance of serotoninergic 5-HT receptors in cocaine addiction
    • Filip M, Alenina N, Bader M, Przegalinski E. Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction. Addiction Biol. 15, 227-249 (2010).
    • (2010) Addiction Biol. , vol.15 , pp. 227-249
    • Filip, M.1    Alenina, N.2    Bader, M.3    Przegalinski, E.4
  • 35
    • 34250358317 scopus 로고    scopus 로고
    • There and back again: A tale of norepinephrine and drug addiction
    • DOI 10.1038/sj.npp.1301263, PII 1301263
    • Weinshenker D, Schroeder JP. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology 32, 1433-1451 (2007). (Pubitemid 46920149)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.7 , pp. 1433-1451
    • Weinshenker, D.1    Schroeder, J.P.2
  • 36
    • 18144430977 scopus 로고    scopus 로고
    • Prazosin, an α-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking
    • DOI 10.1016/j.biopsych.2005.02.003
    • Zhang XY, Kosten TA. Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking. Biol. Psychiatry 57(10), 1202-1204 (2005). (Pubitemid 40615783)
    • (2005) Biological Psychiatry , vol.57 , Issue.10 , pp. 1202-1204
    • Zhang, X.Y.1    Kosten, T.A.2
  • 37
    • 1642488894 scopus 로고    scopus 로고
    • Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats
    • DOI 10.1038/sj.npp.1300346
    • Burmeister JJ, Lungren EM, Kirschner KF, Neisewander JL. Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology 29, 660-668 (2004). (Pubitemid 38402473)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.4 , pp. 660-668
    • Burmeister, J.J.1    Lungren, E.M.2    Kirschner, K.F.3    Neisewander, J.L.4
  • 38
    • 0034042948 scopus 로고    scopus 로고
    • Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking
    • DOI 10.1016/S0893-133X(99)00158-X, PII S0893133X9900158X
    • Erb S, Hitchcott PK, Rajabi H, Mueller D, Shaham Y, Stewart J. a-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking. Neuropsychopharmacology 23, 138-150 (2000). (Pubitemid 30406898)
    • (2000) Neuropsychopharmacology , vol.23 , Issue.2 , pp. 138-150
    • Erb, S.1    Hitchcott, P.K.2    Rajabi, H.3    Mueller, D.4    Shaham, Y.5    Stewart, J.6
  • 39
    • 62949115816 scopus 로고    scopus 로고
    • Therapeutic potential of a2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders
    • Imaki J, Mae Y, Shimizu S, Ohno Y. Therapeutic potential of a2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders. Neurosci. Lett. 454, 143-147 (2009).
    • (2009) Neurosci. Lett. , vol.454 , pp. 143-147
    • Imaki, J.1    Mae, Y.2    Shimizu, S.3    Ohno, Y.4
  • 40
    • 0029763907 scopus 로고    scopus 로고
    • Serotonergic mechanisms in neuroleptic-induced catalepsy in the rat
    • Wadenberg ML. Serotonergic mechanisms in neuroleptic-induced catalepsy in the rat. Neurosci. Biobehav. 20, 325-339 (1996).
    • (1996) Neurosci. Biobehav. , vol.20 , pp. 325-339
    • Wadenberg, M.L.1
  • 41
    • 0031595232 scopus 로고    scopus 로고
    • 2-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat
    • DOI 10.1038/sj.bjp.0701975
    • Kalkman HO, Neumann V, Hoyer D, Tricklebank MD. The role of a2- adrenoceptor antagonism in the anticataleptic properties of the atypical neuroleptic agent, clozapine, in the rat. Br. J. Pharmacology 124, 1550-1556 (1998). (Pubitemid 28360580)
    • (1998) British Journal of Pharmacology , vol.124 , Issue.7 , pp. 1550-1556
    • Kalkman, H.O.1    Neumann, V.2    Hoyer, D.3    Tricklebank, M.D.4
  • 42
    • 0033169884 scopus 로고    scopus 로고
    • Supraspinal D2 receptor involved in antinociception induced by l-tetrahydropalmatine
    • Hu JY, Jin GZ. Supraspinal D2 receptor involved in antinociception induced by l-tetrahydropalmatine. Acta Pharm. Sinica 20, 715-719 (1999).
    • (1999) Acta Pharm. Sinica , vol.20 , pp. 715-719
    • Hu, J.Y.1    Jin, G.Z.2
  • 43
    • 79957593608 scopus 로고    scopus 로고
    • Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine stress or drug-associated cues in rats
    • Figueroa-Guzman Y, Mueller C, Vranjkovic O et al. Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine, stress or drug-associated cues in rats. Drug Alcohol Depend. 116, 72-79 (2011).
    • (2011) Drug Alcohol Depend. , vol.116 , pp. 72-79
    • Figueroa-Guzman, Y.1    Mueller, C.2    Vranjkovic, O.3
  • 44
    • 0030174645 scopus 로고    scopus 로고
    • Preclinical evaluation of pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures
    • DOI 10.1016/0893-133X(95)00274-H
    • Mello NK, Negus SS. Preclinical evaluation of pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures. Neuropsychopharmacology 14, 375-424 (1996). (Pubitemid 26271172)
    • (1996) Neuropsychopharmacology , vol.14 , Issue.6 , pp. 375-424
    • Mello, N.K.1    Negus, S.S.2
  • 45
    • 46649114376 scopus 로고    scopus 로고
    • Controversies in translational research: Drug self-administration
    • Haney M, Spealman R. Controversies in translational research: drug self-administration. Psychopharmacology 199, 403-419 (2008).
    • (2008) Psychopharmacology , vol.199 , pp. 403-419
    • Haney, M.1    Spealman, R.2
  • 46
    • 84856239112 scopus 로고    scopus 로고
    • The in vitro inhibition of human CYP1A2 CYP2D6 and CYP3A4 by tetrahydropalmatine neferine and berberine
    • 10.1002/ptr.3554 Epub ahead of print).
    • Zhao Y, Hellum BH, Liang A, Nilsen OG. The in vitro inhibition of human CYP1A2, CYP2D6 and CYP3A4 by tetrahydropalmatine, neferine and berberine. Phytotherapy Res. doi:10.1002/ptr.3554 (2011) (Epub ahead of print).
    • (2011) Phytotherapy Res.
    • Zhao, Y.1    Hellum, B.H.2    Liang, A.3    Nilsen, O.G.4
  • 47
    • 0031680194 scopus 로고    scopus 로고
    • Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: A review
    • DOI 10.1007/s002130050702
    • Stafford D, LeSage MG, Glowa JR. Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review. Psychopharmacology 139, 169-184 (1998). (Pubitemid 28439514)
    • (1998) Psychopharmacology , vol.139 , Issue.3 , pp. 169-184
    • Stafford, D.1    LeSage, M.G.2    Glowa, J.R.3
  • 48
    • 0029980944 scopus 로고    scopus 로고
    • Progressive ratio schedules in drug self-administration studies in rats: A method to evaluate reinforcing efficacy
    • Richardson NR RD. Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy. J. Neurosci. Methods 66, 1-11 (1996).
    • (1996) J. Neurosci. Methods , vol.66 , pp. 1-11
    • Richardson, N.R.R.D.1
  • 49
    • 0027008644 scopus 로고
    • Brain-stimulation reward: A model for the study of the rewarding effects of abused drugs
    • Kornetsky C, Bain G. Brain-stimulation reward: a model for the study of the rewarding effects of abused drugs. NIDA 124, 73-93 (1992). (Pubitemid 23081975)
    • (1992) NIDA Research Monograph Series , Issue.124 , pp. 73-93
    • Kornetsky, C.1    Bain, G.2
  • 50
    • 0026678044 scopus 로고
    • Use of cocaine-discrimination techniques for preclinical evaluation of candidate therapeutics for cocaine dependence
    • Spealman RD. Use of cocaine-discrimination techniques for preclinical evaluation of candidate therapeutics for cocaine dependence. NIDA 119, 175-179 (1992).
    • (1992) NIDA , vol.119 , pp. 175-179
    • Spealman, R.D.1
  • 51
    • 0038786581 scopus 로고    scopus 로고
    • The reinstatement model of drug relapse: History, methodology and major findings
    • DOI 10.1007/s00213-002-1224-x
    • Shaham Y, Shalev U, Lu L, De Wit H, Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology 168, 3-20 (2003). (Pubitemid 36851158)
    • (2003) Psychopharmacology , vol.168 , Issue.1-2 , pp. 3-20
    • Shaham, Y.1    Shalev, U.2    Lu, L.3    De Wit, H.4    Stewart, J.5
  • 52
    • 0036194738 scopus 로고    scopus 로고
    • Neurobiology of relapse to heroin and cocaine seeking: A review
    • DOI 10.1124/pr.54.1.1
    • Shalev U, Grimm JW, Shaham Y. Neurobiology of relapse to heroin and cocaine seeking: a review. Pharmacol. Rev. 54, 1-42 (2002). (Pubitemid 34208828)
    • (2002) Pharmacological Reviews , vol.54 , Issue.1 , pp. 1-42
    • Shalev, U.1    Grimm, J.W.2    Shaham, Y.3
  • 53
    • 84856287798 scopus 로고    scopus 로고
    • Determination of l-tetrahydropalmatine in human plasma by HPLC and pharmacokinetics of its disintegrating tablets in healthy chinese
    • Li C-W, Zhang S, Gao H-Q, Zhang X-M. Determination of l-tetrahydropalmatine in human plasma by HPLC and pharmacokinetics of its disintegrating tablets in healthy Chinese. Eur. J. Drug Metab. Pharm. 36(4), 257-262 (2011).
    • (2011) Eur. J. Drug Metab. Pharm. , vol.36 , Issue.4 , pp. 257-262
    • Li, C.-W.1    Zhang, S.2    Gao, H.-Q.3    Zhang, X.-M.4
  • 54
    • 33751566611 scopus 로고    scopus 로고
    • Determination of rotundine in human plasma by HPLC and pharmacokinetic studies
    • Zhang J, Tan L, Zhou J, Lu X, Yuan Y. Determination of rotundine in human plasma by HPLC and pharmacokinetic studies. J. China Pharm. Univ. 29, 67-70 (1998).
    • (1998) J. China Pharm. Univ. , vol.29 , pp. 67-70
    • Zhang, J.1    Tan, L.2    Zhou, J.3    Lu, X.4    Yuan, Y.5
  • 55
    • 0025181996 scopus 로고
    • Effects of four dopamine agonists on l-tetrahydropalmatine-induced analgesia and electroacupuncture analgesia in rabbits
    • Wu G, Jiang JW, Wu GC, Cao XD. Effects of four dopamine agonists on l- tetrahydropalmatine-induced analgesia and electroacupuncture analgesia in rabbits. Acta Pharm. Sinica 11, 196-200 (1990). (Pubitemid 20246768)
    • (1990) Acta Pharmacologica Sinica , vol.11 , Issue.3 , pp. 196-200
    • Wu, G.1    Jiang, J.-W.2    Wu, G.-C.3    Cao, X.-D.4
  • 56
    • 65849233445 scopus 로고    scopus 로고
    • Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: A pilot study
    • Yang Z, Shao YC, Li SJ et al. Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. Acta Pharm. Sinica 29, 781-788 (2008).
    • (2008) Acta Pharm. Sinica , vol.29 , pp. 781-788
    • Yang, Z.1    Shao, Y.C.2    Li, S.J.3
  • 57
    • 84863028638 scopus 로고    scopus 로고
    • Therapeutic effects of rotundine combined with methadone in treatment of heroin dependence
    • Hu Y, Qiu Y, Zhong Y, He H. Therapeutic effects of rotundine combined with methadone in treatment of heroin dependence. Chin. J. Drug Abuse Prev. Treat. 12, 270-271 (2006).
    • (2006) Chin. J. Drug Abuse Prev. Treat. , vol.12 , pp. 270-271
    • Hu, Y.1    Qiu, Y.2    Zhong, Y.3    He, H.4
  • 59
    • 0028567033 scopus 로고
    • Acute hepatitis associated with the chinese herbal product jin bu huan
    • Woolf GM, Petrovic LM, Rojter SE et al. Acute hepatitis associated with the Chinese herbal product Jin Bu Huan. Ann. Int. Med. 121, 729-735 (1994).
    • (1994) Ann. Int. Med. , vol.121 , pp. 729-735
    • Woolf, G.M.1    Petrovic, L.M.2    Rojter, S.E.3
  • 61
    • 58149149613 scopus 로고    scopus 로고
    • Levo-tetrahydropalmatine attenuates oxycodone-induced conditioned place preference in rats
    • Liu YL, Yan LD, Zhou PL, Wu CF, Gong ZH. Levo-tetrahydropalmatine attenuates oxycodone-induced conditioned place preference in rats. Eur. J. Pharmacology 602, 321-327 (2009).
    • (2009) Eur. J. Pharmacology , vol.602 , pp. 321-327
    • Liu, Y.L.1    Yan, L.D.2    Zhou, P.L.3    Wu, C.F.4    Gong, Z.H.5


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