Determination of L-tetrahydropalmatine in human plasma by HPLC and pharmacokinetics of its disintegrating tablets in healthy Chinese

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 36, Issue 4, 2011, Pages 257-262

  Li, Chao Wu ^a,b   Zhang, Shuo ^b   Gao, Hai Qing ^b   Zhang, Xiu Mei ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

HPLC; L tetrahydropalmatine; Orally disintegrating tablets; Pharmacokinetics; Rotundine

Indexed keywords

TETRAHYDROPALMATINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CHINESE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; DRUG TOLERABILITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; SENSITIVITY AND SPECIFICITY; TABLET DISINTEGRATION TIME; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADULT; BERBERINE ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; LIMIT OF DETECTION; MALE; TABLETS; YOUNG ADULT;

EID: 84856287798     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-011-0045-x     Document Type: Article

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