Cocaine-induced alterations in dopamine receptor signaling: Implications for reinforcement and reinstatement

Pharmacology and Therapeutics

Volumn 106, Issue 3, 2005, Pages 389-403

  Anderson, S M ^a   Pierce, R C ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Behavioral sensitization; cAMP; Cocaine self administration; CPP; L type calcium channels; Nucleus accumbens

Indexed keywords

CALCIUM CHANNEL L TYPE; COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL BEHAVIOR; CALCIUM TRANSPORT; COCAINE DEPENDENCE; CONDITIONING; DOPAMINERGIC TRANSMISSION; DRUG SELF ADMINISTRATION; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; REINFORCEMENT; REVIEW; SENSITIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; DOPAMINE UPTAKE INHIBITORS; RECEPTORS, DOPAMINE; REINFORCEMENT (PSYCHOLOGY); SIGNAL TRANSDUCTION;

EID: 19444366055     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2004.12.004     Document Type: Review

References (225)

1. B.S. Abrahams, J.D. Rutherford, P.E. Mallet, and R.J. Beninger Place conditioning with the dopamine D1-like receptor agonist SKF 82958 but not SKF 81297 or SKF 77434 Eur J Pharmacol 343 1998 111 118
2. J.M. Ackerman, and F.J. White Decreased activity of rat A10 dopamine neurons following withdrawal from repeated cocaine Eur J Pharmacol 218 1992 171 173
3. O. Aizman, H. Brismar, P. Uhlen, E. Zettergren, A.I. Levey, and H. Forssberg Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons Nat Neurosci 3 2000 226 230
4. K. Akimoto, T. Hamamura, and S. Otsuki Subchronic cocaine treatment enhances cocaine-induced dopamine efflux, studied by in vivo intracerebral dialysis Brain Res 490 1989 339 344
5. A.T. Alleweireldt, K.F. Kirschner, C.B. Blake, and J.L. Neisewander D1-receptor drugs and cocaine-seeking behavior: investigation of receptor mediation and behavioral disruption in rats Psychopharmacology (Berl) 168 2003 109 117
6. S.M. Anderson, A.A. Bari, and R.C. Pierce Administration of the D1-like dopamine receptor antagonist SCH-23390 into the medial nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug-seeking behavior in rats Psychopharmacology (Berl) 168 2003 132 138
7. Anderson, S. M., Ferrari, C. A., & Pierce, R. C. (2004). Systemic administration of the L-type calcium channel antagonist, diltiazem, attenuates cocaine-priming induced reinstatement of drug-seeking behavior. 2004 Abstract Viewer and Itinerary Planner, Program No. 237.17. Washington, DC: Society for Neuroscience, Online.
8. S.M. Antelman, and L.A. Chiodo Dopamine autoreceptor subsensitivity: a mechanism common to the treatment of depression and the induction of amphetamine psychosis Biol Psychiatry 16 1981 717 727
9. A.P. Association Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR 4th ed., text revision 2000 (Washington, DC)
10. D.A. Baker, T.V. Khroyan, L.E. O'Dell, R.A. Fuchs, and J.L. Neisewander Differential effects of intra-accumbens sulpiride on cocaine-induced locomotion and conditioned place preference J Pharmacol Exp Ther 279 1996 392 401
11. D.A. Baker, R.A. Fuchs, S.E. Specio, T.V. Khroyan, and J.L. Neisewander Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference Synapse 30 1998 181 193
12. M.T. Bardo, and R.P.J. Hammer Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: resistance to differential rearing conditions Neuroscience 45 1991 281 290
13. M. Barrot, L. Calza, M. Pozza, M. Le Moal, and P.V. Piazza Differential calbindin-immunoreactivity in dopamine neurons projecting to the rat striatal complex Eur J Neurosci 12 2000 4578 4582
14. M. Barrot, J.D. Olivier, L.I. Perrotti, R.J. DiLeone, O. Berton, and A.J. Eisch CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli Proc Natl Acad Sci U S A 99 2002 11435 11440
15. J.D. Berke, and S.E. Hyman Addiction, dopamine, and the molecular mechanisms of memory Neuron 25 2000 515 532
16. C. Beurrier, and R.C. Malenka Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine J Neurosci 22 2002 5817 5822
17. J.A. Bibb, G.L. Snyder, A. Nishi, Z. Yan, L. Meijer, and A.A. Fienberg Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 1999 669 671
18. J.A. Bibb, J. Chen, J.R. Taylor, P. Svenningsson, A. Nishi, and G.L. Snyder Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 Nature 410 2001 376 380
19. E.J. Bilsky, M.J. Montegut, M.L. Nichols, and L.D. Reid CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine and MDMA conditioned place preferences Pharmacol Biochem Behav 59 1998 215 220
20. M.L. Bouthenet, E. Souil, M.P. Martres, P. Sokoloff, B. Giros, and J.C. Schwartz Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA Brain Res 564 1991 203 219
21. D.R. Britton, P. Curzon, R.G. Mackenzie, J.W. Kebabian, J.E. Williams, and D. Kerkman Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration Pharmacol Biochem Behav 39 1991 911 915
22. S.B. Caine, and G.F. Koob Modulation of cocaine self-administration in the rat through D-3 dopamine receptors Science 260 1993 1814 1816
23. S.B. Caine, and G.F. Koob Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat J Pharmacol Exp Ther 270 1994 209 218
24. S.B. Caine, S.C. Heinrichs, V.L. Coffin, and G.F. Koob Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat Brain Res 692 1995 47 56
25. S.B. Caine, S.S. Negus, N.K. Mello, and J. Bergman Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine J Pharmacol Exp Ther 291 1999 353 360
26. S.B. Caine, S.S. Negus, and N.K. Mello Effects of dopamine D(1-like) and D(2-like) agonists on cocaine self-administration in rhesus monkeys: rapid assessment of cocaine dose-effect functions Psychopharmacology (Berl) 148 2000 41 51
27. W.A.J. Carlezon, and R.A. Wise Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex J Neurosci 16 1996 3112 3122
28. W.A.J. Carlezon, J. Thome, V.G. Olson, S.B. Lane-Ladd, E.S. Brodkin, and N. Hiroi Regulation of cocaine reward by CREB Science 282 1998 2272 2275
29. K.D. Carr Augmentation of drug reward by chronic food restriction: behavioral evidence and underlying mechanisms Physiol Behav 76 2002 353 364
30. C. Cepeda, C.S. Colwell, J.N. Itri, S.H. Chandler, and M.S. Levine Dopaminergic modulation of NMDA-induced whole cell currents in neostriatal neurons in slices: contribution of calcium conductances J Neurophysiol 79 1998 82 94
31. L. Cervo, and R. Samanin Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference Brain Res 673 1995 242 250
32. J. Chao, and E.J. Nestler Molecular neurobiology of drug addiction Annu Rev Med 55 2004 113 132
33. K. Chergui, P. Svenningsson, and P. Greengard Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum Proc Natl Acad Sci U S A 101 2004 2191 2196
34. C.R. Colby, K. Whisler, C. Steffen, E.J. Nestler, and D.W. Self Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine J Neurosci 23 2003 2488 2493
35. J.L. Cornish, and P.W. Kalivas Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction J Neurosci 20 2000 RC89
36. J.L. Cornish, P. Duffy, and P.W. Kalivas A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior Neuroscience 93 1999 1359 1367
37. C.A. Crawford, F.Y. Choi, J.L. Kohutek, S.T. Yoshida, and S.A. McDougall Changes in PKA activity and Gs alpha and Golf alpha levels after amphetamine- and cocaine-induced behavioral sensitization Synapse 51 2004 241 248
38. S.T. Cunningham, and A.E. Kelley Hyperactivity and sensitization to psychostimulants following cholera toxin infusion into the nucleus accumbens J Neurosci 13 1993 2342 2350
39. P.W. Czoty, J.B.J. Justice, and L.L. Howell Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys Psychopharmacology (Berl) 148 2000 299 306
40. G. Damsma, J.G. Pfaus, D. Wenkstern, A.G. Phillips, and H.C. Fibiger Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: comparison with novelty and locomotion Behav Neurosci 106 1992 181 191
41. W. DeJong Relapse prevention: an emerging technology for promoting long-term drug abstinence Int J Addict 29 1994 681 705
42. V. Deroche-Gamonet, D. Belin, and P.V. Piazza Evidence for addiction-like behavior in the rat Science 305 2004 1014 1017
43. T.J. De Vries, A.N. Schoffelmeer, R. Binnekade, and L.J. Vanderschuren Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug self-administration Psychopharmacology (Berl) 143 1999 254 260
44. T.J. De Vries, A.N. Schoffelmeer, R. Binnekade, H. Raaso, and L.J. Vanderschuren Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization Neuropsychopharmacology 26 2002 18 26
45. H. de Wit, and J. Stewart Reinstatement of cocaine-reinforced responding in the rat Psychopharmacology (Berl) 75 1981 134 143
46. J. Diaz, C. Pilon, B. Le Foll, C. Gros, A. Triller, and J.C. Schwartz Dopamine D3 receptors expressed by all mesencephalic dopamine neurons J Neurosci 20 2000 8677 8684
47. C. Duarte, C. Lefebvre, F. Chaperon, M. Hamon, and M.H. Thiebot Effects of a dopamine D3 receptor ligand, BP 897, on acquisition and expression of food-, morphine-, and cocaine-induced conditioned place preference, and food-seeking behavior in rats Neuropsychopharmacology 28 2003 1903 1915
48. A.M. Edelman, D.K. Blumenthal, and E.G. Krebs Protein serine/threonine kinases Annu Rev Biochem 56 1987 567 613
49. A. Ettenberg, H.O. Pettit, F.E. Bloom, and G.F. Koob Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems Psychopharmacology (Berl) 78 1982 204 209
50. B.J. Everitt, J.A. Parkinson, M.C. Olmstead, M. Arroyo, P. Robledo, and T.W. Robbins Associative processes in addiction and reward. The role of amygdala-ventral striatal subsystems Ann N Y Acad Sci 877 1999 412 438
51. W.M. Freeman, M.A. Nader, S.H. Nader, D.J. Robertson, L. Gioia, and S.M. Mitchell Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression J Neurochem 77 2001 542 549
52. R.A. Fuchs, L.T. Tran-Nguyen, S.M. Weber, T.V. Khroyan, and J.L. Neisewander Effects of 7-OH-DPAT on cocaine-seeking behavior and on re-establishment of cocaine self-administration Pharmacol Biochem Behav 72 2002 623 632
53. G.J. Gerber, and R. Stretch Drug-induced reinstatement of extinguished self-administration behavior in monkeys Pharmacol Biochem Behav 3 1975 1055 1061
54. C.R. Gerfen, T.M. Engber, L.C. Mahan, Z. Susel, T.N. Chase, and F.J.J. Monsma D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons Science 250 1990 1429 1432
55. M.A. Gerrits, P. Petromilli, H.G. Westenberg, G. Di Chiara, and J.M. van Ree Decrease in basal dopamine levels in the nucleus accumbens shell during daily drug-seeking behaviour in rats Brain Res 924 2002 141 150
56. N.E. Goeders, and M.J. Kuhar Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens Alcohol Drug Res 7 1987 207 216
57. P.M. Gonzales, K.J. Boswell, C.L. Hubbell, and L.D. Reid Isradipine blocks cocaine's ability to facilitate pressing for intracranial stimulation Pharmacol Biochem Behav 58 1997 1117 1122
58. M. Graziella De Montis, C. Co, S.I. Dworkin, and J.E. Smith Modifications of dopamine D1 receptor complex in rats self-administering cocaine Eur J Pharmacol 362 1998 9 15
59. D.M. Grech, R.D. Spealman, and J. Bergman Self-administration of D1 receptor agonists by squirrel monkeys Psychopharmacology (Berl) 125 1996 97 104
60. H.J. Groenewegen, C.I. Wright, A.V. Beijer, and P. Voorn Convergence and segregation of ventral striatal inputs and outputs Ann N Y Acad Sci 877 1999 49 63
61. S. Hansen, A.H. Bergvall, and S. Nyiredi Interaction with pups enhances dopamine release in the ventral striatum of maternal rats: a microdialysis study Pharmacol Biochem Behav 45 1993 673 676
62. M.B. Harrison, R.G. Wiley, and G.F. Wooten Selective localization of striatal D1 receptors to striatonigral neurons Brain Res 528 1990 317 322
63. S.E. Hemby, G.H. Jones, J.B.J. Justice, and D.B. Neill Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine Psychopharmacology (Berl) 106 1992 330 336
64. D.J. Henry, and F.J. White Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens J Pharmacol Exp Ther 258 1991 882 890
65. D.J. Henry, and F.J. White The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons J Neurosci 15 1995 6287 6299
66. D.J. Henry, M.A. Greene, and F.J. White Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration J Pharmacol Exp Ther 251 1989 833 839
67. D.J. Henry, X.T. Hu, and F.J. White Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization Psychopharmacology (Berl) 140 1998 233 242
68. L. Hernandez, and B.G. Hoebel Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis Life Sci 42 1988 1705 1712
69. S. Hernandez-Lopez, J. Bargas, D.J. Surmeier, A. Reyes, and E. Galarraga D1 receptor activation enhances evoked discharge in neostriatal medium spiny neurons by modulating an L-type Ca2+ conductance J Neurosci 17 1997 3334 3342
70. B. Hope, B. Kosofsky, S.E. Hyman, and E.J. Nestler Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine Proc Natl Acad Sci U S A 89 1992 5764 5768
71. B.T. Hope, H.E. Nye, M.B. Kelz, D.W. Self, M.J. Iadarola, and Y. Nakabeppu Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments Neuron 13 1994 1235 1244
72. C.B. Hubner, and J.E. Moreton Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat Psychopharmacology (Berl) 105 1991 151 156
73. M. Hummel, and E.M. Unterwald Intra-accumbens pertussis toxin sensitizes rats to the locomotor activating effects of a single cocaine challenge Brain Res 965 2003 100 107
74. Y.L. Hurd, F. Weiss, G.F. Koob, N.E. And, and U. Ungerstedt Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbens: an in vivo microdialysis study Brain Res 498 1989 199 203
75. R.B. Innis, and G.K. Aghajanian Pertussis toxin blocks autoreceptor-mediated inhibition of dopaminergic neurons in rat substantia nigra Brain Res 411 1987 139 143
76. T.R. Insel Is social attachment an addictive disorder? Physiol Behav 79 2003 351 357
77. D.M. Jackson, and A. Westind-Danielsson Dopamine receptors: molecular biology, biochemistry and behavioural aspects Pharmal Ther 64 1994 291 370
78. J.H. Jaffe, N.G. Cascella, K.M. Kumor, and M.A. Sherer Cocaine-induced cocaine craving Psychopharmacology (Berl) 97 1989 59 64
79. A.L. Jongen-Relo, G.J. Docter, A.J. Jonker, E. Vreugdenhil, H.J. Groenewegen, and P. Voorn Differential effects of dopamine depletion on the binding and mRNA levels of dopamine receptors in the shell and core of the rat nucleus accumbens Brain Res Mol Brain Res 25 1994 333 343
80. A.L. Jongen-Relo, G.J. Docter, A.J. Jonker, and P. Voorn Differential localization of mRNAs encoding dopamine D1 or D2 receptors in cholinergic neurons in the core and shell of the rat nucleus accumbens Brain Res Mol Brain Res 28 1995 169 174
81. P.W. Kalivas, and P. Duffy Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens Synapse 5 1990 48 58
82. P.W. Kalivas, and P. Duffy Time course of extracellular dopamine and behavioral sensitization to cocaine: I. Dopamine axon terminals J Neurosci 13 1993 266 275
83. P.W. Kalivas, and J. Stewart Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity Brain Res Brain Res Rev 16 1991 223 244
84. P.W. Kalivas, L. Churchill, and M.A. Klitenick The circuitry mediating the translation of motivational stimuli into adaptive motor responses Limbic motor circuits and neuropsychiatry 1993 237 275
85. P.W. Kalivas, R.C. Pierce, J. Cornish, and B.A. Sorg A role for sensitization in craving and relapse in cocaine addiction J Psychopharmacol 12 1998 49 53
86. K. Kamata, and G.V. Rebec Iontophoretic evidence for subsensitivity of postsynaptic dopamine receptors following long-term amphetamine administration Eur J Pharmacol 106 1984 393 397
87. R. Karler, S.A. Turkanis, L.M. Partlow, and L.D. Calder Calcium channel blockers and behavioral sensitization Life Sci 49 1991 165 170
88. J.W. Kebabian, G.L. Petzold, and P. Greengard Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor" Proc Natl Acad Sci U S A 69 1972 2145 2149
89. M.B. Kelz, J. Chen, W.A.J. Carlezon, K. Whisler, L. Gilden, and A.M. Beckmann Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine Nature 401 1999 272 276
90. Z.U. Khan, A. Gutierrez, R. Martin, A. Penafiel, A. Rivera, and A. de la Calle Dopamine D5 receptors of rat and human brain Neuroscience 100 2000 689 699
91. T.V. Khroyan, R.A. Fuchs, D.A. Baker, and J.L. Neisewander Effects of D3-preferring agonists 7-OH-PIPAT and PD-128,907 on motor behaviors and place conditioning Behav Pharmacol 8 1997 65 74
92. T.V. Khroyan, R.L. Barrett-Larimore, J.K. Rowlett, and R.D. Spealman Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists J Pharmacol Exp Ther 294 2000 680 687
93. T.V. Khroyan, D.M. Platt, J.K. Rowlett, and R.D. Spealman Attenuation of relapse to cocaine seeking by dopamine D1 receptor agonists and antagonists in non-human primates Psychopharmacology (Berl) 168 2003 124 131
94. E.A. Kiyatkin, and A. Gratton Electrochemical monitoring of extracellular dopamine in nucleus accumbens of rats lever-pressing for food Brain Res 652 1994 225 234
95. E.A. Kiyatkin, and E.A. Stein Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study Neuroscience 64 1995 599 617
96. M.S. Kleven, B.D. Perry, W.L. Woolverton, and L.S. Seiden Effects of repeated injections of cocaine on D1 and D2 dopamine receptors in rat brain Brain Res 532 1990 265 270
97. C.M. Knapp, M.M. Foye, D.A. Ciraulo, and C. Kornetsky The type IV phosphodiesterase inhibitors, Ro 20-1724 and rolipram, block the initiation of cocaine self-administration Pharmacol Biochem Behav 62 1999 151 158
98. P.M. Kunko, D. French, and S. Izenwasser Alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids J Pharmacol Exp Ther 285 1998 277 284
99. A. Kuzmin, E. Zvartau, G.L. Gessa, M.C. Martellotta, and W. Fratta Calcium antagonists isradipine and nimodipine suppress cocaine and morphine intravenous self-administration in drug-naive mice Pharmacol Biochem Behav 41 1992 497 500
100. L.G. Laurier, W.A. Corrigall, and S.R. George Dopamine receptor density, sensitivity and mRNA levels are altered following self-administration of cocaine in the rat Brain Res 634 1994 31 40
101. C. Le Moine, and B. Bloch D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum J Comp Neurol 355 1995 418 426
102. G. Le Pen, D. Duterte-Boucher, and J. Costentin Place conditioning with cocaine and the dopamine uptake inhibitor GBR12783 Neuroreport 7 1996 2839 2842
103. A.I. Leshner Addiction is a brain disease, and it matters Science 278 1997 45 47
104. Y. Li, F.J. White, and M.E. Wolf Pharmacological reversal of behavioral and cellular indices of cocaine sensitization in the rat Psychopharmacology (Berl) 151 2000 175 183
105. R.M. Liao, Y.H. Chang, and S.H. Wang Influence of SCH23390 and spiperone on the expression of conditioned place preference induced by d-amphetamine or cocaine in the rat Chin J Physiol 41 1998 85 92
106. R.M. Liao, Y.H. Chang, S.H. Wang, and C.H. Lan Distinct accumbal subareas are involved in place conditioning of amphetamine and cocaine Life Sci 67 2000 2033 2043
107. S.C. Licata, and R.C. Pierce The roles of calcium/calmodulin-dependent and Ras/mitogen-activated protein kinases in the development of psychostimulant-induced behavioral sensitization J Neurochem 85 2003 14 22
108. S.C. Licata, A.Y. Freeman, A.F. Pierce-Bancroft, and R.C. Pierce Repeated stimulation of L-type calcium channels in the rat ventral tegmental area mimics the initiation of behavioral sensitization to cocaine Psychopharmacology (Berl) 152 2000 110 118
109. Y.F. Liu, O. Civelli, Q.Y. Zhou, and P.R. Albert Cholera toxin-sensitive 3′,5′-cyclic adenosine monophosphate and calcium signals of the human dopamine-D1 receptor: selective potentiation by protein kinase A Mol Endocrinol 6 1992 1815 1824
110. X.Y. Lu, M.B. Ghasemzadeh, and P.W. Kalivas Expression of D1 receptor, D2 receptor, substance P and enkephalin messenger RNAs in the neurons projecting from the nucleus accumbens Neuroscience 82 1998 767 780
111. L. Lu, J.W. Grimm, Y. Shaham, and B.T. Hope Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats J Neurochem 85 2003 1604 1613
112. R. Maldonado, P. Robledo, A.J. Chover, S.B. Caine, and G.F. Koob D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat Pharmacol Biochem Behav 45 1993 239 242
113. P.E. Mallet, and R.J. Beninger 7-OH-DPAT produces place conditioning in rats Eur J Pharmacol 261 1994 R5 R6
114. M.C. Martellotta, A. Kuzmin, P. Muglia, G.L. Gessa, and W. Fratta Effects of the calcium antagonist isradipine on cocaine intravenous self-administration in rats Psychopharmacology (Berl) 113 1994 378 380
115. M.T. Martin-Iverson, and A.R. Reimer Effects of nimodipine and/or haloperidol on the expression of conditioned locomotion and sensitization to cocaine in rats Psychopharmacology (Berl) 114 1994 315 320
116. B.A. Mattingly, T.C. Hart, K. Lim, and C. Perkins Selective antagonism of dopamine D1 and D2 receptors does not block the development of behavioral sensitization to cocaine Psychopharmacology (Berl) 114 1994 239 242
117. R.D. Mayfield, G. Larson, and N.R. Zahniser Cocaine-induced behavioral sensitization and D1 dopamine receptor function in rat nucleus accumbens and striatum Brain Res 573 1992 331 335
118. B. Mayr, and M. Montminy Transcriptional regulation by the phosphorylation-dependent factor CREB Nat Rev Mol Cell Biol 2 2001 599 609
119. C.A. McClung, and E.J. Nestler Regulation of gene expression and cocaine reward by CREB and DeltaFosB Nat Neurosci 6 2003 1208 1215
120. K. McFarland, and P.W. Kalivas The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior J Neurosci 21 2001 8655 8663
121. J.H. Meador-Woodruff Update on dopamine receptors Ann Clin Psychiatry 6 1994 79 90
122. J.H. Meador-Woodruff, A. Mansour, D.K. Grandy, S.P. Damask, O. Civelli, and S.J.J. Watson Distribution of D5 dopamine receptor mRNA in rat brain Neurosci Lett 145 1992 209 212
123. J.H. Meador-Woodruff, S.P. Damask, and S.J.J. Watson Differential expression of autoreceptors in the ascending dopamine systems of the human brain Proc Natl Acad Sci U S A 91 1994 8297 8301
124. M.R. Melis, and A. Argiolas Dopamine and sexual behavior Neurosci Biobehav Rev 19 1995 19 38
125. N.K. Mello Animal models of alcoholism: progress and prospects R. Davidson Modification of pathological behavior, experimental analysis of etiology and therapy 1979 Gardner Press New York 273 333
126. P.L. Mellon, C.H. Clegg, L.A. Correll, and G.S. McKnight Regulation of transcription by cyclic AMP-dependent protein kinase Proc Natl Acad Sci U S A 86 1989 4887 4891
127. G. Mengod, M.T. Vilaro, H.B. Niznik, R.K. Sunahara, P. Seeman, and B.F. O'Dowd Visualization of a dopamine D1 receptor mRNA in human and rat brain Brain Res Mol Brain Res 10 1991 185 191
128. G. Mengod, M.T. Villaro, G.B. Landwehrmeyer, M.I. Martinez-Mir, H.B. Niznik, and R.K. Sunahara Visualization of dopamine D1, D2 and D3 receptor mRNAs in human and rat brain Neurochem Int 20 1992 33S 43S (Suppl)
129. G.E. Meredith, R. Agolia, M.P. Arts, H.J. Groenewegen, and D.S. Zahm Morphological differences between projection neurons of the core and shell in the nucleus accumbens of the rat Neuroscience 50 1992 149 162
130. G.E. Meredith, A. Pattiselanno, H.J. Groenewegen, and S.N. Haber Shell and core in monkey and human nucleus accumbens identified with antibodies to calbindin-D28k J Comp Neurol 365 1996 628 639
131. M.J. Miserendino, and E.J. Nestler Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens Brain Res 674 1995 299 306
132. C. Missale, S.R. Nash, S.W. Robinson, M. Jaber, and M.G. Caron Dopamine receptors: from structure to function Physiol Rev 78 1998 189 225
133. G.J. Mogenson, D.L. Jones, and C.Y. Yim From motivation to action: functional interface between the limbic system and the motor system Prog Neurobiol 14 1980 69 97
134. R.J. Moore, S.L. Vinsant, M.A. Nader, L.J. Porrino, and D.P. Friedman Effect of cocaine self-administration on dopamine D2 receptors in rhesus monkeys Synapse 30 1998 88 96
135. M.A. Morency, and R.J. Beninger Dopaminergic substrates of cocaine-induced place conditioning Brain Res 399 1986 33 41
136. D. Mueller, and J. Stewart Cocaine-induced conditioned place preference: reinstatement by priming injections of cocaine after extinction Behav Brain Res 115 2000 39 47
137. N.H. Mutschler, and J. Bergman Effects of chronic administration of the D1 receptor partial agonist SKF 77434 on cocaine self-administration in rhesus monkeys Psychopharmacology (Berl) 160 2002 362 370
138. M.A. Nader, and R.H. Mach Self-administration of the dopamine D3 agonist 7-OH-DPAT in rhesus monkeys is modified by prior cocaine exposure Psychopharmacology (Berl) 125 1996 13 22
139. W.J. Nauta, and V.B. Domesick Crossroads of limbic and striatal circuitry: hypothlamic-nigral connections K.E. Livingston O. Hornykiewicz Limbic mechanisms 1978 Plenum New York 75 93
140. A. Nazarian, S.J. Russo, E.D. Festa, M. Kraish, and V. Quinones-Jenab The role of D1 and D2 receptors in the cocaine conditioned place preference of male and female rats Brain Res Bull 63 2004 295 299
141. S.S. Negus, N.K. Mello, X. Lamas, and J.H. Mendelson Acute and chronic effects of flupenthixol on the discriminative stimulus and reinforcing effects of cocaine in rhesus monkeys J Pharmacol Exp Ther 278 1996 879 890
142. E.J. Nestler Molecular basis of long-term plasticity underlying addiction Nat Rev Neurosci 2 2001 119 128
143. E.J. Nestler, R.Z. Terwilliger, J.R. Walker, K.A. Sevarino, and R.S. Duman Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain J Neurochem 55 1990 1079 1082
144. E.J. Nestler, M. Barrot, and D.W. Self DeltaFosB: a sustained molecular switch for addiction Proc Natl Acad Sci U S A 98 2001 11042 11046
145. A. Nishi, J.A. Bibb, G.L. Snyder, H. Higashi, A.C. Nairn, and P. Greengard Amplification of dopaminergic signaling by a positive feedback loop Proc Natl Acad Sci U S A 97 2000 12840 12845
146. A.B. Norman, M.K. Norman, J.F. Hall, and V.L. Tsibulsky Priming threshold: a novel quantitative measure of the reinstatement of cocaine self-administration Brain Res 831 1999 165 174
147. L. Pani, A. Kuzmin, M. Diana, G. De Montis, G.L. Gessa, and Z.L. Rossetti Calcium receptor antagonists modify cocaine effects in the central nervous system differently Eur J Pharmacol 190 1990 217 221
148. L. Pani, A. Kuzmin, M.C. Martellotta, G.L. Gessa, and W. Fratta The calcium antagonist PN 200-110 inhibits the reinforcing properties of cocaine Brain Res Bull 26 1991 445 447
149. J. Peris, S.J. Boyson, W.A. Cass, P. Curella, L.P. Dwoskin, and G. Larson Persistence of neurochemical changes in dopamine systems after repeated cocaine administration J Pharmacol Exp Ther 253 1990 38 44
150. M. Perugini, and P. Vezina Amphetamine administered to the ventral tegmental area sensitizes rats to the locomotor effects of nucleus accumbens amphetamine J Pharmacol Exp Ther 270 1994 690 696
151. H.O. Pettit, and J.B.J. Justice Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis Pharmacol Biochem Behav 34 1989 899 904
152. H.O. Pettit, A. Ettenberg, F.E. Bloom, and G.F. Koob Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats Psychopharmacology (Berl) 84 1984 167 173
153. J.G. Pfaus, G. Damsma, D. Wenkstern, and H.C. Fibiger Sexual activity increases dopamine transmission in the nucleus accumbens and striatum of female rats Brain Res 693 1995 21 30
154. R.C. Pierce, P. Duffy, and P.W. Kalivas Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens Synapse 20 1995 33 36
155. R.C. Pierce, E.A. Quick, D.C. Reeder, Z.R. Morgan, and P.W. Kalivas Calcium-mediated second messengers modulate the expression of behavioral sensitization to cocaine J Pharmacol Exp Ther 286 1998 1171 1176
156. D.M. Platt, J.K. Rowlett, and R.D. Spealman Modulation of cocaine and food self-administration by low- and high-efficacy D1 agonists in squirrel monkeys Psychopharmacology (Berl) 157 2001 208 216
157. D.L. Pruitt, C.A. Bolanos, and S.A. McDougall Effects of dopamine D1 and D2 receptor antagonists on cocaine-induced place preference conditioning in preweanling rats Eur J Pharmacol 283 1995 125 131
158. 2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment J Neurosci 24 2004 7464 7476
159. R. Ranaldi, D. Pocock, R. Zereik, and R.A. Wise Dopamine fluctuations in the nucleus accumbens during maintenance, extinction, and reinstatement of intravenous D-amphetamine self-administration J Neurosci 19 1999 4102 4109
160. R. Ranaldi, Z. Wang, and W.L. Woolverton Reinforcing effects of D2 dopamine receptor agonists and partial agonists in rhesus monkeys Drug Alcohol Depend 64 2001 209 217
161. D.C. Roberts, and G.F. Koob Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats Pharmacol Biochem Behav 17 1982 901 904
162. T.E. Robinson, and K.C. Berridge The neural basis of drug craving: an incentive-sensitization theory of addiction Brain Res Brain Res Rev 18 1993 247 291
163. Z.A. Rodd-Henricks, D.L. McKinzie, T.K. Li, J.M. Murphy, and W.J. McBride Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats J Pharmacol Exp Ther 303 2002 1216 1226
164. S. Scheggi, R. Rauggi, G. Nanni, A. Tagliamonte, and C. Gambarana Repeated acetyl-l-carnitine administration increases phospho-Thr34 DARPP-32 levels and antagonizes cocaine-induced increase in Cdk5 and phospho-Thr75 DARPP-32 levels in rat striatum Eur J Neurosci 19 2004 1609 1620
165. S. Schenk Effects of GBR 12909, WIN 35,428 and indatraline on cocaine self-administration and cocaine seeking in rats Psychopharmacology (Berl) 160 2002 263 270
166. S. Schenk, and D. Gittings Effects of SCH 23390 and eticlopride on cocaine-seeking produced by cocaine and WIN 35,428 in rats Psychopharmacology (Berl) 168 2003 118 123
167. S. Schenk, and B. Partridge Cocaine-seeking produced by experimenter-administered drug injections: dose-effect relationships in rats Psychopharmacology (Berl) 147 1999 285 290
168. S. Schenk, B. Partridge, and T.S. Shippenberg Reinstatement of extinguished drug-taking behavior in rats: effect of the kappa-opioid receptor agonist, U69593 Psychopharmacology (Berl) 151 2000 85 90
169. C.W. Schindler, S.R. Tella, J. Prada, and S.R. Goldberg Calcium channel blockers antagonize some of cocaine's cardiovascular effects, but fail to alter cocaine's behavioral effects J Pharmacol Exp Ther 272 1995 791 798
170. Schmidt, H. D., & Pierce, R. C. (2003). Intra-accumbal shell administration of the D1-like dopamine receptor agonist SKF-81297 reinstates drug-seeking behavior. 2003 Abstract Viewer and Itinerary Planner, Program number 422.12. Washington DC: Society for Neuroscience. Online.
171. D.S. Segal, and R. Kuczenski Repeated cocaine administration induces
172. D.W. Self, and L. Stein The D1 agonists SKF 82958 and SKF 77434 are self-administered by rats Brain Res 582 1992 349 352
173. D.W. Self, R.Z. Terwilliger, E.J. Nestler, and L. Stein Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement J Neurosci 14 1994 6239 6247
174. D.W. Self, W.J. Barnhart, D.A. Lehman, and E.J. Nestler Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists Science 271 1996 1586 1589
175. D.W. Self, L.M. Genova, B.T. Hope, W.J. Barnhart, J.J. Spencer, and E.J. Nestler Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior J Neurosci 18 1998 1848 1859
176. D.W. Self, D.A. Karanian, and J.J. Spencer Effects of the novel D1 dopamine receptor agonist ABT-431 on cocaine self-administration and reinstatement Ann N Y Acad Sci 909 2000 133 144
177. Y. Shaham, U. Shalev, L. Lu, H. De Wit, and J. Stewart The reinstatement model of drug relapse: history, methodology and major findings Psychopharmacology (Berl) 168 2003 3 20
178. D.R. Sibley, F.J.J. Monsma, and Y. Shen Molecular neurobiology of dopaminergic receptors Int Rev Neurobiol 35 1993 391 415
179. R.S. Sinnott, R.H. Mach, and M.A. Nader Dopamine D2/D3 receptors modulate cocaine's reinforcing and discriminative stimulus effects in rhesus monkeys Drug Alcohol Depend 54 1999 97 110
180. P. Sokoloff, B. Giros, M.P. Martres, M.L. Bouthenet, and J.C. Schwartz Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics Nature 347 1990 146 151
181. F.C. Sousa, P.B. Gomes, D.S. Macedo, M.M. Marinho, and G.S. Viana Early withdrawal from repeated cocaine administration upregulates muscarinic and dopaminergic D2-like receptors in rat neostriatum Pharmacol Biochem Behav 62 1999 15 20
182. R.D. Spealman, J. Bergman, and S. Rosenzweig-Lipson Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists Psychopharmacology (Berl) 133 1997 283 292
183. R.D. Spealman, R.L. Barrett-Larimore, J.K. Rowlett, D.M. Platt, and T.V. Khroyan Pharmacological and environmental determinants of relapse to cocaine-seeking behavior Pharmacol Biochem Behav 64 1999 327 336
184. C. Spyraki, H.C. Fibiger, and A.G. Phillips Cocaine-induced place preference conditioning: lack of effects of neuroleptics and 6-hydroxydopamine lesions Brain Res 253 1982 195 203
185. G.D. Stanwood, I. Lucki, and P. McGonigle Differential regulation of dopamine D2 and D3 receptors by chronic drug treatments J Pharmacol Exp Ther 295 2000 1232 1240
186. J. Stewart Reinstatement of heroin and cocaine self-administration behavior in the rat by intracerebral application of morphine in the ventral tegmental area Pharmacol Biochem Behav 20 1984 917 923
187. C.D. Striplin, and P.W. Kalivas Correlation between behavioral sensitization to cocaine and G protein ADP-ribosylation in the ventral tegmental area Brain Res 579 1992 181 186
188. Substance Abuse and Mental Health Services Administration Overview of findings from the 2002 national survey on drug use and health NHSDA Series H-21, DHHS Publication No. SMA 03-3774 2003 Office of Applied Studies Rockville, MD
189. D.J. Surmeier, J. Eberwine, C.J. Wilson, Y. Cao, A. Stefani, and S.T. Kitai Dopamine receptor subtypes colocalize in rat striatonigral neurons Proc Natl Acad Sci U S A 89 1992 10178 10182
190. D.J. Surmeier, J. Bargas, H.C.J. Hemmings, A.C. Nairn, and P. Greengard Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons Neuron 14 1995 385 397
191. T. Suzuki, Y. Shiozaki, Y. Masukawa, and M. Misawa Effects of calcium antagonists on the cocaine- and methamphetamine-induced conditioned place preference Arukoru Kenkyu to Yakubutsu Izon 27 1992 81 90
192. A.L. Svingos, S. Periasamy, and V.M. Pickel Presynaptic dopamine D(4) receptor localization in the rat nucleus accumbens shell Synapse 36 2000 222 232
193. L.W. Swanson The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat Brain Res Bull 9 1982 321 353
194. S.R. Tella, B. Ladenheim, A.M. Andrews, S.R. Goldberg, and J.L. Cadet Differential reinforcing effects of cocaine and GBR-12909: biochemical evidence for divergent neuroadaptive changes in the mesolimbic dopaminergic system J Neurosci 16 1996 7416 7427
195. J.M. Tepper, S.F. Sawyer, and P.M. Groves Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis J Neurosci 7 1987 2794 2806
196. J.M. Tepper, B.C. Sun, L.P. Martin, and I. Creese Functional roles of dopamine D2 and D3 autoreceptors on nigrostriatal neurons analyzed by antisense knockdown in vivo J Neurosci 17 1997 2519 2530
197. R.Z. Terwilliger, D. Beitner-Johnson, K.A. Sevarino, S.M. Crain, and E.J. Nestler A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function Brain Res 548 1991 100 110
198. B.E. Thompson, B.D. Sachs, K.M. Kantak, and J.A. Cherry The type IV phosphodiesterase inhibitor rolipram interferes with drug-induced conditioned place preference but not immediate early gene induction in mice Eur J Neurosci 19 2004 2561 2568
199. H. Ujike, K. Akiyama, and S. Otsuki D-2 but not D-1 dopamine agonists produce augmented behavioral response in rats after subchronic treatment with methamphetamine or cocaine Psychopharmacology (Berl) 102 1990 459 464
200. A.S. Undie, J. Weinstock, H.M. Sarau, and E. Friedman Evidence for a distinct D1-like dopamine receptor that couples to activation of phosphoinositide metabolism in brain J Neurochem 62 1994 2045 2048
201. E.M. Unterwald, B.M. Cox, M.J. Kreek, T.E. Cote, and S. Izenwasser Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity Synapse 15 1993 33 38
202. E.M. Unterwald, A. Ho, J.M. Rubenfeld, and M.J. Kreek Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration J Pharmacol Exp Ther 270 1994 1387 1396
203. L.J. Vanderschuren, and P.W. Kalivas Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies Psychopharmacology (Berl) 151 2000 99 120
204. L.J. Vanderschuren, A.N. Schoffelmeer, A.H. Mulder, and T.J. De Vries Dopaminergic mechanisms mediating the long-term expression of locomotor sensitization following pre-exposure to morphine or amphetamine Psychopharmacology (Berl) 143 1999 244 253
205. K.E. Vanover, M.S. Kleven, and W.L. Woolverton Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359 Behav Pharmacol 2 1991 151 159
206. P. Voorn, C.R. Gerfen, and H.J. Groenewegen Compartmental organization of the ventral striatum of the rat: immunohistochemical distribution of enkephalin, substance P, dopamine, and calcium-binding protein J Comp Neurol 289 1989 189 201
207. S.R. Vorel, C.R.J. Ashby, M. Paul, X. Liu, R. Hayes, and J.J. Hagan Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats J Neurosci 22 2002 9595 9603
208. J.R. Walters, D.A. Bergstrom, J.H. Carlson, T.N. Chase, and A.R. Braun D1 dopamine receptor activation required for postsynaptic expression of D2 agonist effects Science 236 1987 719 722
209. C.L. Walters, Y.C. Kuo, and J.A. Blendy Differential distribution of CREB in the mesolimbic dopamine reward pathway J Neurochem 87 2003 1237 1244
210. K. Wedzony, A. Chocyk, M. Mackowiak, K. Fijal, and A. Czyrak Cortical localization of dopamine D4 receptors in the rat brain-immunocytochemical study J Physiol Pharmacol 51 2000 205 221
211. M.R. Weed, and W.L. Woolverton The reinforcing effects of dopamine D1 receptor agonists in rhesus monkeys J Pharmacol Exp Ther 275 1995 1367 1374
212. M.R. Weed, I.A. Paul, L.P. Dwoskin, S.E. Moore, and W.L. Woolverton The relationship between reinforcing effects and in vitro effects of D1 agonists in monkeys J Pharmacol Exp Ther 283 1997 29 38
213. D.M. Weiner, A.I. Levey, R.K. Sunahara, H.B. Niznik, B.F. O'Dowd, and P. Seeman D1 and D2 dopamine receptor mRNA in rat brain Proc Natl Acad Sci U S A 88 1991 1859 1863
214. F. Weiss, A. Markou, M.T. Lorang, and G.F. Koob Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration Brain Res 593 1992 314 318
215. F.J. White, and R.Y. Wang Electrophysiological evidence for A10 dopamine autoreceptor subsensitivity following chronic D-amphetamine treatment Brain Res 309 1984 283 292
216. N.M. White, M.G. Packard, and N. Hiroi Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens Psychopharmacology (Berl) 103 1991 271 276
217. R.A. Wise, A. Murray, and M.A. Bozarth Bromocriptine self-administration and bromocriptine-reinstatement of cocaine-trained and heroin-trained lever pressing in rats Psychopharmacology (Berl) 100 1990 355 360
218. R.A. Wise, P. Newton, K. Leeb, B. Burnette, D. Pocock, and J.B.J. Justice Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats Psychopharmacology (Berl) 120 1995 10 20
219. W.L. Woolverton Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys Pharmacol Biochem Behav 24 1986 531 535
220. M. Xu, X.T. Hu, D.C. Cooper, R. Moratalla, A.M. Graybiel, and F.J. White Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice Cell 79 1994 945 955
221. K.K. Yung, and J.P. Bolam Localization of dopamine D1 and D2 receptors in the rat neostriatum: synaptic interaction with glutamate- and GABA-containing axonal terminals Synapse 38 2000 413 420
222. L. Zaborszky, G.F. Alheid, M.C. Beinfeld, L.E. Eiden, L. Heimer, and M. Palkovits Cholecystokinin innervation of the ventral striatum: a morphological and radioimmunological study Neuroscience 14 1985 427 453
223. D.S. Zahm, and J.S. Brog On the significance of subterritories in the "accumbens" part of the rat ventral striatum Neuroscience 50 1992 751 767
224. L. Zhou, T. Furuta, and T. Kaneko Chemical organization of projection neurons in the rat accumbens nucleus and olfactory tubercle Neuroscience 120 2003 783 798
225. K.A. Zito, G. Vickers, and D.C. Roberts Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens Pharmacol Biochem Behav 23 1985 1029 1036