Dopamine receptor partial agonists could address the duality of cocaine craving

Trends in Pharmacological Sciences

Volumn 21, Issue 1, 2000, Pages 6-9

  Childress, Anna Rose ^a,b   O'Brien, Charles P ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; BP 897; COCAINE; DOPAMINE; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; ECOPIPAM; HALOPERIDOL; UNCLASSIFIED DRUG;

ANHEDONIA; CLINICAL TRIAL; COCAINE DEPENDENCE; DOPAMINERGIC TRANSMISSION; HUMAN; LETHARGY; LIMBIC SYSTEM; NONHUMAN; NOTE; PRIORITY JOURNAL; REWARD; WITHDRAWAL SYNDROME;

EID: 0033970304     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(99)01422-4     Document Type: Short Survey

References (55)

1. Pilla M.et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist. Nature. 400:1999;371-375.
2. Childress A.R. The pull of positive incentive motivation in human craving states. NIDA Res. Mongr. 1999;. in press.
3. Gawin F.H., Kleber H.D. Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations. Arch. Gen. Psychiatry. 43:1986;107-113.
4. Jaffe J.J.et al. Cocaine-induced cocaine craving. Psychopharmacology. 97:1989;59-64.
5. Childress A.R.et al. Conditioned craving and arousal in cocaine addiction: a preliminary report. NIDA Res. Monogr. 88:1988;74-80.
6. Ehrman R.N.et al. Conditioned responses to cocaine-related stimuli in cocaine abuse patients. Psychopharmacology. 107:1992;523-529.
7. Koob G.F. Drug addiction: the yin and yang of hedonic homeostasis. Neuron. 16:1996;893-896.
8. Stewart J. Conditioned and unconditioned drug effects in relapse to opiate and stimulant drug self-administration. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 7:1983;591-597.
9. Kiyatkin E., Stein E.A. Conditioned changes in nuclues accumberns dopamine signal established by intravenous cocaine in rats. Neurosci. Lett. 211:1996;73-76.
10. DiCiano P.et al. The relation between dopamine oxidation currents in the nucleus accumbens and conditioned increases in motor activity in rats following repeated administration of d-amphetamine or cocaine. Eur. J. Neurosci. 10:1998;784-785.
11. Khantzian E.J. An extreme case of cocaine dependence and marked improvement with methylphenidate treatment. Am. J. Psychiatry. 140:1983;784-785.
12. Gawin F.et al. Methylphenidate treatment of cocaine abusers without attention deficit disorder: a negative report. Am. J. Drug Alcohol Abuse. 11:1985;193-197.
13. Wise R.A. Neurobiology of addiction. Curr. Opin. Neurobiol. 6:1996;243-251.
14. Roberts D.C.S., Ranaldi R. Effect of dopaminergic drugs on cocaine reinforcement. Clin. Neuropharmacol. 18:1995;S84.
15. Berger S.P.et al. Haloperidol antagonism of cue-elicited cocaine craving. Lancet. 347:1996;504-508.
16. Hollister L.E. Neuroleptic dysphoria: so what's new? Biol. Psychiatry. 31:1992;531-532.
17. Self D.W.et al. Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science. 271:1996;1586-1589.
18. Coffin V.L.et al. SCH 39166, a potential antipsychotic drug, does not evoke movement disorders in cebus monkeys. Neurochem. Int. 20(Suppl.):1992;141S-145S.
19. Roberts D.C.S.et al. Baclofen attenuates the reinforcing effects of cocaine in rats. Neuropsychopharmacology. 15:1996;417-423.
20. Dewey S.L.et al. A novel strategy for the treatment of cocaine addiction. Synapse. 30:1998;119-129.
21. Ling W.et al. Baclofen as a cocaine anti-craving medication: a preliminary clinical study. Neuropsychopharmacology. 18:1998;403-404.
22. Aaronson S.C.et al. Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology. 119:1995;179-185.
23. Shaham Y.et al. CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats. Psychopharmacology. 137:1998;184-190.
24. Goeders N. A neuroendocrine role in cocaine reinforcement. Psychoneuroendocrinology. 22:1997;237-259.
25. Spealman R.D., Bergman J. Modulation of the discriminative stimulus effects of cocaine by mu and kappa opioids. J. Pharmacol. Exp. Ther. 261:1993;607-615.
26. Shippenberg T.S. Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists. Pharmacol. Biochem. Behav. 57:1997;449-455.
27. Kalivas P.W., Duffy P. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. J. Neurochem. 70:1998;1497-1502.
28. Glowa J.R.et al. Sustained decrease in cocaine-maintained responding in rhesus monkeys with 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate, a long-acting ester derivative of GBR 12909. J. Med. Chem. 39:1996;4689-4691.
29. Grabowski J. Methylphenidate (MP): an adjunct for cocaine dependence? NIDA Res. Monogr. 162:1996;150.
30. Katz J.L., Witkin J.M. Selective effects of the D1 dopamine receptor agonist, SKF 38393, on behavior maintained by cocaine injection in squirrel monkeys. Psychopharmacology. 109:1992;241-244.
31. Spealman R.D.et al. Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists. Psychopharmacology. 133:1997;283-292.
32. Pulvirenti L., Koob G.F. Dopamine receptor agonists, partial agonists and psychostimulant addiction. Trends Pharmacol. Sci. 15:1994;374-379.
33. Spealman R.D. Discriminative stimulus effects of cocaine in squirrel monkeys: lack of antagonism by the dopamine D2 partial agonists terguride, SDZ 208-911, and SDZ 208-912. Pharmacol. Biochem. Behav. 51:1995;661-665.
34. Weissenborn R.et al. Effects of dopamine agonists and antagonists on cocaine-induced operant responding for a cocaine-associated stimulus. Psychopharmacology. 126:1996;311-322.
35. Caine S.B., Koob G.F. Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science. 260:1993;1814-1816.
36. Whitelaw R.B.et al. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement. Psychopharmacology. 127:1996;213-214.
37. Hitchcott P.K., Phillips G.D. Effects of intra-amygdala R(+) 7-OH-DPAT on intra-accumbens d-amphetamine-associated learning. I. Pavlovian conditioning. Psychopharmacology. 140:1998;300-309.
38. Weiss F.et al. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Res. 593:1992;314-318.
39. Stone A.M.et al. Cocaine use by schizophrenic outpatients who receive depot neuroleptic medication. Hosp. Community Psychiatry. 44:1993;176-177.
40. Meil W.M., See R.E. Lesions of the basolateral amygdala abolish the ability of drug associated cues to reinstate responding during withdrawal from self-administered cocaine. Behav. Brain Res. 87:1997;139-148.
41. Hernandez L., Hoebel B.G. Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci. 42:1988;1705-1712.
42. Mark G.P.et al. An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release. Pharmacol. Biochem. Behav. 48:1994;651-660.
43. Pfaus J.G., Phillips A.G. Role of dopamine in anticipatory and consummatory aspects of sexual behavior in the male rat. Behav. Neurosci. 105:1991;727-743.
44. Bergh C.et al. Altered dopamine function in pathological gambling. Psychol. Med. 27:1997;473-475.
45. Maldonado-Irizarry C.S.et al. Blockade of D-1 and D-2 dopamine receptors attenuates 'relapse' elicited by cocaine-associated environmental stimuli following prolonged extinction. Soc. Neurosci. Abstr. 22:1996;925.
46. Khroyan T.V.et al. Opposing effects of D1 and D2-like dopamine agonists in modulating the priming effects of cocaine. Soc. Neurosci. Abstr. 25:1999;1071.
47. Rocha B.A.et al. Cocaine self-administration in dopamine-transporter knockout mice. Nat. Neurosci. 1:1998;132-137.
48. Robbins S.J.et al. Using cue reactivity to screen medications for cocaine abuse: a test of amantadine hydrochloride. Addict. Behav. 17:1992;491-499.
49. Pilla M.et al. D3 receptor partial agonist reduced cocaine but not heroin-seeking behaviour measured using a second-order schedule of reinforcement. Soc. Neurosci. Abstr. 25:1999;1072.
50. Baxter L.R.et al. Localization of neurochemical effects of cocaine and other stimulants in the human brain. J. Clin. Psychiatry. 49:1988;23-26.
51. Volkow N.D.et al. Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse. 14:1993;169-177.
52. Childress A.R.et al. Regional brain blood flow during induced cocaine craving. Soc. Neurosci. Abstr. 20:1994;1632.
53. Grant S.et al. Activation of memory circuits during cue-elicited cocaine craving. Proc. Natl. Acad. Sci. U. S. A. 93:1996;12040-12045.
54. Childress A.R.et al. Limbic activation during cue-induced cocaine craving. Am. J. Psychiatry. 156:1999;11-18.
55. Garavan H.et al. Cognitive dimensions of cue-induced cocaine craving. Soc. Neurosci. Abstr. 24:1998;2175.