Mutagenesis-mediated decrease of pathogenicity as a feature of the mutant spectrum of a viral population

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Sanz Ramos, Marta ^a,b,c   Rodríguez Calvo, Teresa ^a   Sevilla, Noemí ^a  

^a Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria   (Spain)

^b CSIC   (Spain)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PHENFORMIN; RIBAVIRIN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE MUTATION; IN VIVO STUDY; LD 50; MOLECULAR CLONING; MOUSE; MUTAGENESIS; NONHUMAN; PHENOTYPE; POPULATION DYNAMICS; PROGENY; TREATMENT RESPONSE; VIRUS ATTENUATION; VIRUS TITRATION; VIRUS VIRULENCE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CRICETINAE; FOOT-AND-MOUTH DISEASE VIRUS; LETHAL DOSE 50; MICE; MUTAGENESIS; RIBAVIRIN; SERIAL PASSAGE; VIRULENCE;

FOOT-AND-MOUTH DISEASE VIRUS; FOOT-AND-MOUTH DISEASE VIRUS - TYPE C; MUS; RNA VIRUSES;

EID: 84862999117     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039941     Document Type: Article

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