Topology of evolving, mutagenized viral populations: Quasispecies expansion, compression, and operation of negative selection

BMC Evolutionary Biology

Volumn 8, Issue 1, 2008, Pages

  Ojosnegros, Samuel ^a   Agudo, Rubén ^a   Sierra, Macarena ^a   Briones, Carlos ^b,c   Sierra, Saleta ^a,d   González López, Claudia ^a,e   Domingo, Esteban ^a,b,c   Cristina, Juan ^a,f  

^a CSIC   (Spain)

^b INSTITUTO NACIONAL DE TÉCNICA AEROESPACIAL   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; FLUOROURACIL; GUANIDINE; RIBAVIRIN; MUTAGENIC AGENT; VIRUS RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENTROPY; FOOT AND MOUTH DISEASE VIRUS; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENOME; IN VITRO STUDY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; VIRUS MUTATION; ANALYSIS OF VARIANCE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; DRUG EFFECT; GENETIC SELECTION; GENETICS; HAMSTER; MOLECULAR EVOLUTION; MUTATION; PHYLOGENY; STATISTICAL MODEL; VIRUS GENOME;

FOOT-AND-MOUTH DISEASE VIRUS;

ANALYSIS OF VARIANCE; ANIMALS; CELL LINE; CRICETINAE; EVOLUTION, MOLECULAR; FOOT-AND-MOUTH DISEASE VIRUS; GENOME, VIRAL; LIKELIHOOD FUNCTIONS; MODELS, BIOLOGICAL; MUTAGENESIS; MUTAGENS; MUTATION; PHYLOGENY; RIBAVIRIN; RNA, VIRAL; SELECTION (GENETICS);

EID: 49649112207     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-8-207     Document Type: Article

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