-
1
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction and type 2 diabetes
-
Zhang C.-Y., Baffy G., Perret P., Krauss S., Peroni O., Grujic D., Hagen T., Vidal-Puig A., Boss O., Kim Y.-B., Zheng X., Wheeler M., Shulman G., Chan C., Lowell B. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction and type 2 diabetes. Cell 2001, 105:745-755.
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.-Y.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
Vidal-Puig, A.8
Boss, O.9
Kim, Y.-B.10
Zheng, X.11
Wheeler, M.12
Shulman, G.13
Chan, C.14
Lowell, B.15
-
2
-
-
0037181143
-
Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets
-
Brown J.E., Thomas S., Digby J.E., Dunmore S.J. Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets. FEBS Lett. 2002, 513:189-192.
-
(2002)
FEBS Lett.
, vol.513
, pp. 189-192
-
-
Brown, J.E.1
Thomas, S.2
Digby, J.E.3
Dunmore, S.J.4
-
3
-
-
0036724133
-
Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition
-
Patane G., Anello M., Piro S., Vigeri R., Purello F., Rabuazzo A. Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition. Diabetes 2002, 51:2749-2756.
-
(2002)
Diabetes
, vol.51
, pp. 2749-2756
-
-
Patane, G.1
Anello, M.2
Piro, S.3
Vigeri, R.4
Purello, F.5
Rabuazzo, A.6
-
4
-
-
67649641804
-
Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function
-
Pi J., Bai Y., Daniel K.W., Liu D., Lyght O., Edelstein D., Brownlee M., Corkey B.E., Collins S. Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function. Endocrinology 2009, 150:3040-3048.
-
(2009)
Endocrinology
, vol.150
, pp. 3040-3048
-
-
Pi, J.1
Bai, Y.2
Daniel, K.W.3
Liu, D.4
Lyght, O.5
Edelstein, D.6
Brownlee, M.7
Corkey, B.E.8
Collins, S.9
-
5
-
-
0035117975
-
Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells
-
Hong Y., Fink B.D., Dillon J.S., Sivitz W.I. Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells. Endocrinology 2001, 142:249-256.
-
(2001)
Endocrinology
, vol.142
, pp. 249-256
-
-
Hong, Y.1
Fink, B.D.2
Dillon, J.S.3
Sivitz, W.I.4
-
6
-
-
0032929816
-
Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function
-
Wang M.Y., Shimabukuro M., Lee Y., Trinh K.Y., Chen J.L., Newgard C.B., Unger R.H. Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function. Diabetes 1999, 48:1020-1025.
-
(1999)
Diabetes
, vol.48
, pp. 1020-1025
-
-
Wang, M.Y.1
Shimabukuro, M.2
Lee, Y.3
Trinh, K.Y.4
Chen, J.L.5
Newgard, C.B.6
Unger, R.H.7
-
7
-
-
33845949078
-
Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species
-
Produit-Zengaffinen N., Davis-Lameloise N., Perreten H., Becard D., Gjinovci A., Keller P.A., Wollheim C.B., Herrera P., Muzzin P., Assimacopoulos-Jeannet F. Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species. Diabetologia 2007, 50:84-93.
-
(2007)
Diabetologia
, vol.50
, pp. 84-93
-
-
Produit-Zengaffinen, N.1
Davis-Lameloise, N.2
Perreten, H.3
Becard, D.4
Gjinovci, A.5
Keller, P.A.6
Wollheim, C.B.7
Herrera, P.8
Muzzin, P.9
Assimacopoulos-Jeannet, F.10
-
8
-
-
0013807029
-
Coated charcoal immunoassay of insulin
-
Herbert V., Lau K.S., Gottlieb C.W., Bleicher S.J. Coated charcoal immunoassay of insulin. J. Clin. Endocrinol. Metab. 1965, 25:1375-1384.
-
(1965)
J. Clin. Endocrinol. Metab.
, vol.25
, pp. 1375-1384
-
-
Herbert, V.1
Lau, K.S.2
Gottlieb, C.W.3
Bleicher, S.J.4
-
9
-
-
0000374054
-
A simple method for in vitro metabolic studies using small volumes of tissue and medium
-
Keen H., Field J., Pastan H. A simple method for in vitro metabolic studies using small volumes of tissue and medium. Metab. Clin. Exp. 1963, 12:143-147.
-
(1963)
Metab. Clin. Exp.
, vol.12
, pp. 143-147
-
-
Keen, H.1
Field, J.2
Pastan, H.3
-
10
-
-
34047095833
-
Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta cell sensitivity
-
Ma Z., Portwood N., Brodin D., Grill V., Björklund A. Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta cell sensitivity. Diabetes 2007, 56:1095-1106.
-
(2007)
Diabetes
, vol.56
, pp. 1095-1106
-
-
Ma, Z.1
Portwood, N.2
Brodin, D.3
Grill, V.4
Björklund, A.5
-
11
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-56.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-56
-
-
Mosmann, T.1
-
12
-
-
0033985092
-
Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver
-
Morillas M., Clotet J., Rubí B., Serra D., Asins G., Ariño J., Hegardt F.G. Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver. FEBS Lett. 2000, 466:183-186.
-
(2000)
FEBS Lett.
, vol.466
, pp. 183-186
-
-
Morillas, M.1
Clotet, J.2
Rubí, B.3
Serra, D.4
Asins, G.5
Ariño, J.6
Hegardt, F.G.7
-
13
-
-
0034804062
-
Uncoupling protein 2 participates in cellular defense against oxidative stress in clonal beta cells
-
Li L.X., Skorpen F., Egeberg K.W., Jørgensen I., Grill V. Uncoupling protein 2 participates in cellular defense against oxidative stress in clonal beta cells. Biochem. Biophys. Res. Commun. 2001, 282:273-277.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 273-277
-
-
Li, L.X.1
Skorpen, F.2
Egeberg, K.W.3
Jørgensen, I.4
Grill, V.5
-
14
-
-
38149130672
-
Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion
-
Affourtit C., Brand M.D. Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion. Biochem. J. 2008, 409:199-204.
-
(2008)
Biochem. J.
, vol.409
, pp. 199-204
-
-
Affourtit, C.1
Brand, M.D.2
-
15
-
-
10944265062
-
Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression
-
Joseph J.W., Koshkin V., Saleh M.C., Sivitz W.I., Zhang C.Y., Lowell B.B., Chan C.B., Wheeler M.B. Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression. J. Biol. Chem. 2004, 279:51049-51056.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51049-51056
-
-
Joseph, J.W.1
Koshkin, V.2
Saleh, M.C.3
Sivitz, W.I.4
Zhang, C.Y.5
Lowell, B.B.6
Chan, C.B.7
Wheeler, M.B.8
-
16
-
-
58649106881
-
Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1
-
Galetti S., Sarre A., Perreten H., Produit-Zengaffinen N., Muzzin P., Assimacopoulos-Jeannet F. Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1. Pflugers Arch. 2009, 457:931-940.
-
(2009)
Pflugers Arch.
, vol.457
, pp. 931-940
-
-
Galetti, S.1
Sarre, A.2
Perreten, H.3
Produit-Zengaffinen, N.4
Muzzin, P.5
Assimacopoulos-Jeannet, F.6
-
17
-
-
77951274305
-
Uncoupling protein UCP2: when mitochondrial activity meets immunity
-
Emre Y., Nübel T. Uncoupling protein UCP2: when mitochondrial activity meets immunity. FEBS Lett. 2010, 584:1437-1442.
-
(2010)
FEBS Lett.
, vol.584
, pp. 1437-1442
-
-
Emre, Y.1
Nübel, T.2
-
18
-
-
50149084247
-
UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival
-
Diao J., Allister E.M., Koshkin V., Lee S.C., Bhattacharjee A., Tang C., Giacca A., Chan C.B., Wheeler M.B. UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival. Proc. Natl. Acad. Sci. USA 2008, 105:12057-12062.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 12057-12062
-
-
Diao, J.1
Allister, E.M.2
Koshkin, V.3
Lee, S.C.4
Bhattacharjee, A.5
Tang, C.6
Giacca, A.7
Chan, C.B.8
Wheeler, M.B.9
-
19
-
-
0038700699
-
Cytotoxic effect of doxycycline and its implications for tet-on gene expression systems
-
Ermak G., Cancasci V.J., Davies K.J. Cytotoxic effect of doxycycline and its implications for tet-on gene expression systems. Anal. Biochem. 2003, 318:152-154.
-
(2003)
Anal. Biochem.
, vol.318
, pp. 152-154
-
-
Ermak, G.1
Cancasci, V.J.2
Davies, K.J.3
-
20
-
-
80755168930
-
Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion
-
Robson-Doucette C.A., Sultan S., Allister E.M., Wikstrom J.D., Koshkin V., Bhattacharjee A., Prentice K.J., Sereda S.B., Shirihai O.S., Wheeler M.B. Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion. Diabetes 2011, 60:2710-2719.
-
(2011)
Diabetes
, vol.60
, pp. 2710-2719
-
-
Robson-Doucette, C.A.1
Sultan, S.2
Allister, E.M.3
Wikstrom, J.D.4
Koshkin, V.5
Bhattacharjee, A.6
Prentice, K.J.7
Sereda, S.B.8
Shirihai, O.S.9
Wheeler, M.B.10
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