Chemical-protein interactome and its application in off-target identification

Interdisciplinary Sciences – Computational Life Sciences

Volumn 3, Issue 1, 2011, Pages 22-30

  Yang, Lun ^a,b,f   Wang, Ke Jian ^a   Wang, Li Shan ^a   Jegga, Anil G ^c,d   Qin, Sheng Ying ^a   He, Guang ^a   Chen, Jian ^a   Xiao, Yue ^a   He, Lin ^a,b,e  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

^e Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^f NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

adverse drug reaction; chemical protein interactome; drug repositioning; off system; off target

Indexed keywords

DRUG; PROTEIN;

BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; METHODOLOGY; PHARMACEUTICS; PROTEIN DATABASE; PROTEIN DOMAIN; REVIEW;

COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, PROTEIN; MODELS, MOLECULAR; PHARMACEUTICAL PREPARATIONS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84862833676     PISSN: 19132751     EISSN: 18671462     Source Type: Journal    
DOI: 10.1007/s12539-011-0051-8     Document Type: Article

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