Identifying unexpected therapeutic targets via chemical-protein interactome

PLoS ONE

Volumn 5, Issue 3, 2010, Pages

  Yang, Lun ^a,b   Chen, Jian ^a,b   Shi, Leming ^c   Hudock, Michael P ^a   Wang, Kejian ^a   He, Lin ^a,b,d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^d Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ARGINASE 1; ASPARAGINASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE III; CD81 ANTIGEN; CLOZAPINE; CONCANAVALIN A; DONEPEZIL; ESTROGEN RECEPTOR; GALANTAMINE; GLUTATHIONE SYNTHASE; HEME OXYGENASE 1; HEPSIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE 7; HUPERZINE A; IMMUNOGLOBULIN LAMBDA CHAIN; LOXAPINE; MALATE DEHYDROGENASE; MOLINDONE; MONOPHENOL MONOOXYGENASE; OLANZAPINE; PHYSOSTIGMINE; RIVASTIGMINE; SEX HORMONE BINDING GLOBULIN; SQUALENE SYNTHASE; TACRINE; UNINDEXED DRUG; VASOPRESSIN V1A RECEPTOR; DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG TARGETING; HUMAN; MOLECULAR DOCKING; PROTEIN INTERACTION; BIOLOGY; COMPUTER SIMULATION; GENETICS; METABOLISM; METHODOLOGY; PHARMACEUTICS; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN DOMAIN; PROTEOMICS; REPRODUCIBILITY; RISK; STATISTICAL MODEL;

ALZHEIMER DISEASE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, PROTEIN; HISTONE DEACETYLASES; HUMANS; MODELS, STATISTICAL; PHARMACEUTICAL PREPARATIONS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEOMICS; RECEPTORS, ESTROGEN; REPRODUCIBILITY OF RESULTS; RISK; TECHNOLOGY, PHARMACEUTICAL;

EID: 77949760141     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009568     Document Type: Article

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