Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways

Food and Chemical Toxicology

Volumn 50, Issue 5, 2012, Pages 1734-1740

  Liao, Ching Lung ^a   Lai, Kuang Chi ^b,c   Huang, An Cheng ^d   Yang, Jai Sing ^a   Lin, Jen Jyh ^a,e   Wu, Shin Hwar ^f   Gibson Wood, W ^g   Lin, Jaung Geng ^a   Chung, Jing Gung ^a,h  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^d St Mary's Medicine Nursing and Management College   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^g UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^h ASIA UNIVERSITY   (Taiwan)

Author keywords

AKT PKB; Gallic acid; Human osteosarcoma U 2 OS cells; Migration and invasion; MMP 2 9; PKC

Indexed keywords

GALLIC ACID; GELATINASE A; GELATINASE B; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL STRAIN U 2 OS; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOSARCOMA CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; DNA PRIMERS; GALLIC ACID; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84862830254     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.02.033     Document Type: Article

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