Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-κB activity and downregulation of PI3K/AKT/small GTPase signals

Food and Chemical Toxicology

Volumn 48, Issue 8-9, 2010, Pages 2508-2516

  Ho, Hsieh Hsun ^a   Chang, Chi Sen ^a,b   Ho, Wei Chi ^c   Liao, Sheng You ^a   Wu, Cheng Hsun ^d   Wang, Chau Jong ^a,e  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c JEN AI HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Gallic acid; Gastric cancer; Metastasis; MMP 2 9; Phenolic acid; PI3K AKT

Indexed keywords

CAFFEIC ACID; F ACTIN; GALLIC ACID; GELATINASE A; GELATINASE B; GUANOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN CDC42; PROTEIN KINASE B; PROTOCATECHUIC ACID; RAC1 PROTEIN; RAS PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; ACTIN; ANTINEOPLASTIC AGENT; CAFFEIC ACID DERIVATIVE; HYDROXYBENZOIC ACID DERIVATIVE; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; ONCOPROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; METASTASIS INHIBITION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; WOUND HEALING; ADENOCARCINOMA; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; DRUG EFFECTS; GEL MOBILITY SHIFT ASSAY; IMMUNOPRECIPITATION; METABOLISM; NEOPLASM METASTASIS; PATHOLOGY; STOMACH NEOPLASMS; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ADENOCARCINOMA; ANTICARCINOGENIC AGENTS; CAFFEIC ACIDS; CELL LINE, TUMOR; CELL SURVIVAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GALLIC ACID; HUMANS; HYDROXYBENZOIC ACIDS; IMMUNOPRECIPITATION; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MONOMERIC GTP-BINDING PROTEINS; NEOPLASM METASTASIS; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; WOUND HEALING; HYDROXYBENZOATES; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77955056022     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.06.024     Document Type: Article

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