Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways

Oncology Reports

Volumn 26, Issue 1, 2011, Pages 177-184

  Liu, Kuo Ching ^a,b   Huang, An Cheng ^c   Wu, Ping Ping ^a   Lin, Hui Yi ^a   Chueh, Fu Shin ^d   Yang, Jai Sing ^a   Lu, Chi Cheng ^b   Chiang, Jo Hua ^b   Meng, Menghsiao ^b   Chung, Jing Gung ^a,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c St Mary's Medicine Nursing and Management College   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

Cell invasion; Cell migration; Gallic acid; Matrix metalloproteinase 2 9; PC 3 human prostate cancer cells

Indexed keywords

FOCAL ADHESION KINASE; GALLIC ACID; GELATIN; GELATINASE A; GELATINASE B; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE; SON OF SEVENLESS HOMOLOG 1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; THREONINE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL MIGRATION; CELL STRAIN PC 3; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; GALLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INFLAMMATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 79955796236     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1264     Document Type: Article

References (48)

1. Hernandez BY, Green MD, Cassel KD, Pobutsky AM, Vu V and Wilkens LR: Preview of Hawaii Cancer Pacts and Figures 2010. Hawaii Med J 69: 223-224, 2010.
2. Williams H and Powell IJ: Epidemiology, pathology, and genetics of prostate cancer among African Americans compared with other ethnicities. Methods Mol Biol 472: 439-453, 2009.
3. Steinberg GD, Carter BS, Beaty TH, Childs B and Walsh PC: Family history and the risk of prostate cancer. Prostate 17: 337-347, 1990.
4. Koeneman KS, Yeung F and Chung LW: Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 39: 246-261, 1999. (Pubitemid 29244499)
5. Koutsilieris M: Osteoblastic metastasis in advanced prostate cancer. Anticancer Res 13: 443-449, 1993.
6. Kilian M, Gregor JI, Heukamp I, et al: Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer. Prostaglandins Leukot Essent Fatty Acids 75: 429-434, 2006. (Pubitemid 44649358)
7. Mizutani K, Kofuji K and Shirouzu K: The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer. Surg Today 30: 614-621, 2000. (Pubitemid 30489838)
8. Gullu IH, Kurdoglu M and Akalin I: The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer. Br J Cancer 82: 249, 2000. (Pubitemid 30008993)
9. Guruvayoorappan C and Kuttan G: Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 mice. Immunopharmacol Immunotoxicol 30: 711-727, 2008.
10. Okada N, Ishida H, Murata N, Hashimoto D, Seyama Y and Kubota S: Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer. Biochem Biophys Res Commun 288: 212-216, 2001. (Pubitemid 32999748)
11. Waas ET, Wobbes T, Lomme RM, DeGroot J, Ruers T and Hendriks T: Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis. Br J Surg 90: 1556-1564, 2003. (Pubitemid 37533174)
12. Hong WK and Sporn MB: Recent advances in chemoprevention of cancer. Science 278: 1073-1077, 1997.
13. AbouEl Hassan MA, Braam SR and Kruyt FA: Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small cell lung cancer cells. Cancer Gene Ther 13: 1105-1114, 2006. (Pubitemid 44760108)
14. Fung-Kee-Fung M, Oliver T, Elit L, Oza A, Hirte HW and Bryson P: Optimal chemotherapy treatment for women with recurrent ovarian cancer. Curr Oncol 14: 195-208, 2007.
15. Ng TB, He JS, Niu SM, et al: A gallic acid derivative and polysaccharides with antioxidative activity from rose (Rosa rugosa) flowers. J Pharm Pharmacol 56: 537-545, 2004. (Pubitemid 38455620)
16. Kim SH, Jun CD, Suk K, et al: Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells. Toxicol Sci 91: 123-131, 2006.
17. Chakraborty A, Ferk F, Simic T, et al: DNA-protective effects of sumach (Rhus coriaria L.), a common spice: results of human and animal studies. Mntat Res 661: 10-17, 2009.
18. Shahrzad S, Aoyagi K, Winter A, Koyama A and Bitsch I: Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans. J Nutr 131: 1207-1210, 2001. (Pubitemid 32275101)
19. Atkinson BL, Blackman AJ and Faber H: The degradation of the natural pyrethrins in crop storage. J Agric Food Chem 52: 280-287, 2004.
20. Kang MS, Oh JS, Kang IC, Hong SJ and Choi CH: Inhibitory effect of methyl gallate and gallic acid on oral bacteria. J Microbiol 46: 744-750, 2008.
21. Kaur M, Velmurugan B, Rajamanickam S, Agarwal R and Agarwal C: Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice. Pharm Res 26: 2133-2140, 2009.
22. Inoue M, Suzuki R, Koide T, Sakaguchi N, Ogihara Y and Yabu Y: Antioxidant, gallic acid, induces apoptosis in HL-60RG cells. Biochem Biophys Res Commun 204: 898-904, 1994. (Pubitemid 24344005)
23. Veluri R, Singh RP, Liu Z, Thompson JA, Agarwal R and Agarwal C: Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells. Carcinogenesis 27: 1445-1453, 2006. (Pubitemid 43985419)
24. Lu CC, Yang JS, Huang AC, et al: Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells. Mol Nutr Food Res 54: 967-976, 2010.
25. Chiang JH, Yang JS, Ma CY, et al: Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-medialed apoptosis in SNUT human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. Chem Res Toxicol 24: 20-29, 2011.
26. Chen YY, Chiang SY, Lin JG, et al: Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9. Int J Oncol 36: 1113-1120, 2010.
27. Lai KC, Huang AC, Hsu SC, et al: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. J Agric Food Chem 58: 2935-2942, 2010.
28. Lin HJ, Su CC, Lu HF, et al: Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression. Oncol Rep 23: 665-670, 2010.
29. Chen PN, Hsieh YS, Chiang CL, Chiou HL, Yang SF and Chu SC: Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway. J Dent Res 85: 220-225, 2006.
30. Chen PN, Chu SC, Chiou HL, Kuo WH, Chiang CL and Hsieh YS: Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line. Cancer Lett 235: 248-259, 2006.
31. Fidler IJ: The organ microenvironment and cancer metastasis. Differentiation 70: 498-505, 2002.
32. Chakraborti S, Mandal M, Das S, Mandal A and Chakraborti T: Regulation of matrix metalloproteinases: an overview. Mol Cell Biochem 253: 269-285, 2003.
33. Coussens LM and Werb Z: Matrix metalloproteinases and the development of cancer. Chem Biol 3: 895-904, 1996.
34. Zhang L, Shi J, Feng J, Klocker H, Lee C and Zhang J: Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer. Prostate Cancer Prostatic Dis 7: 327-332, 2004. (Pubitemid 41721791)
35. Bjornland K, Flatmark K, Pettersen S, Aaasen AO, Fodstad O and Maelandsmo GM: Matrix metalloproteinases participate in osteosarcoma invasion. J Surg Res 127: 151-156, 2005. (Pubitemid 41080627)
36. Overall CM and Kleifeld O: Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer 6: 227-239, 2006. (Pubitemid 43292566)
37. Duffy MJ: The urokinase plasminogen activator system: role in malignancy. Curr Pharm Des 10: 39-49, 2004.
38. Eccles SA: Parallels in invasion and angiogenesis provide pivotal points for therapeutic intervention. Int J Dev Biol 48: 583-598, 2004.
39. Hollborn M, Stathopoulos C, Steffen A, Wiedemann P, Kohen L and Bringmann A: Positive feedback regulation between MMP-9 and VEGF in human RPE cells. Invest Ophthalmol Vis Sci 48: 4360-4367, 2007. (Pubitemid 351261070)
40. Carpenter CL and Cantley LC: Phosphoinositide kinases. Curr Opin Cell Biol 8: 153-158, 1996. (Pubitemid 26109087)
41. Allen NE, Key TJ, Dossus L, et al: Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition (EPIC). Endocr Relat Cancer 15: 485-497, 2008. (Pubitemid 351880837)
42. Osipo C, Meeke K, Liu H, et al: Trastuzumab therapy for tamoxifen-stimulated endometrial cancer. Cancer Res 65: 8504-8513, 2005. (Pubitemid 41330619)
43. Zhang S, Li Z, Wu X, Huang Q, Shen HM and Ong CN: Methyl-3-indolylacetate inhibits cancer cell invasion by targeting the MEK1/2-ERK1/2 signaling pathway. Mol Cancer Ther 5: 3285-3293, 2006. (Pubitemid 46092072)
44. Chung TW, Lee YC and Kim CH: Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential. FASEB J 18: 1123-1125, 2004.
45. Simon C, Simon M, Vucelic G, et al: The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. Exp Cell Res 271: 344-355, 2001. (Pubitemid 33141216)
46. Khokha R, Zimmer MJ, Graham CH, Lala PK and Waterhouse P: Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells. J Natl Cancer Inst 84: 1017-1022, 1992.
47. Park MJ, Lee JY, Kwak HJ, et al: Arsenic trioxide (As2O3) inhibits invasion of HT1080 human fibrosarcoma cells: role of nuclear factor-kappaB and reactive oxygen species. J Cell Biochem 95: 955-969, 2005.
48. Ramer R and Hinz B: Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. J Natl Cancer Inst 100: 59-69, 2008. (Pubitemid 351767340)