Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and cytokines in lung tissues of C57BL/6 mice

Immunopharmacology and Immunotoxicology

Volumn 30, Issue 4, 2008, Pages 711-727

  Guruvayoorappan, Chandrasekaran ^a   Kuttan, Girija ^a  

^a AMALA CANCER RESEARCH CENTRE   (India)

Author keywords

Amentoflavone; Chemoprevention; Invasion; Metastasis; Motility; nm23

Indexed keywords

AMENTOFLAVONE; CYTOKINE; GELATINASE A; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT EXTRACT; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN LYSINE 6 OXIDASE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER INVASION; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; GENE; LUNG METASTASIS; LUNG PARENCHYMA; MALE; MELANOMA; MELANOMA CELL; METASTASIS INHIBITION; MOUSE; NM23 GENE; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIFLAVONOIDS; CYTOKINES; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN-LYSINE 6-OXIDASE; STAT1 TRANSCRIPTION FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; MUS;

EID: 54949091958     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970802278276     Document Type: Article

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