IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Duan, Xin ^a   Ponomareva, Larissa ^a,b   Veeranki, Sudhakar ^a   Choubey, Divaker ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; PROTEIN IFI16; PROTEIN P53; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA BINDING PROTEIN; GLUCOSE; IFI16 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; AUTOPHAGY; CELL ENERGY; CELL SURVIVAL; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; FETUS; FIBROBLAST; GLUCOSE INTAKE; HUMAN; HUMAN CELL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION; CELL NUCLEUS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; AUTOPHAGY; CELL CYCLE PROTEINS; CELL NUCLEUS; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FIBROBLASTS; GLUCOSE; HUMANS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 79955839356     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019532     Document Type: Article

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