Quantification of protein posttranslational modifications using stable isotope and mass spectrometry: I: Principles and applications

Analytical Biochemistry

Volumn 421, Issue 2, 2012, Pages 506-516

  Jiang, Xinzhao Grace ^a   Apostol, Izydor ^a   Luo, Quanzhou ^a   Lewis, Jeffrey ^a   Keener III, Ronald ^a   Luo, Shun ^a   Jerums, Matthew ^a   Zhang, Xin ^a   Wypych, Jette ^a   Huang, Gang ^a  

^a AMGEN INC   (United States)

Author keywords

Critical quality attributes; Mass spectrometry; Posttranslational modification; Quality by design; Quantification; Recombinant protein; Stable isotope labeling

Indexed keywords

ISOTOPES; MAMMALS; MASS SPECTROMETRY; PRODUCT DESIGN;

CRITICAL QUALITY; POST-TRANSLATIONAL MODIFICATIONS; QUALITY BY DESIGNS; QUANTIFICATION; STABLE-ISOTOPE LABELING;

RECOMBINANT PROTEINS;

RECOMBINANT PROTEIN;

ACCURACY; ARTICLE; ISOTOPE LABELING; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MODIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

MAMMALIA;

EID: 84862815798     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.12.004     Document Type: Article

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