Trends in capacity utilization for therapeutic monoclonal antibody production

mAbs

Volumn 1, Issue 2, 2009, Pages 151-156

  Langer, Eric S ^a  

^a BioPlan Associates Inc   (United States)

Author keywords

Biopharmaceutical; Capacity; Constraints; Facility; Manufacturing; Monoclonal antibody; Production; Survey

Indexed keywords

MONOCLONAL ANTIBODY;

ARTICLE; CONTRACT; CONTROLLED STUDY; DRUG MANUFACTURE; UTILIZATION REVIEW; WORK CAPACITY;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOPHARMACEUTICS; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; DRUG INDUSTRY; EUROPE; HUMANS; UNITED STATES;

EID: 77953667906     PISSN: 19420862     EISSN: None     Source Type: Journal    
DOI: 10.4161/mabs.1.2.7802     Document Type: Article

References (8)

1. Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256:495-497
2. Das RC, Morrow KJ. Antibody technologies rise to new challenges. Am Biotechnol Lab 2007; 25:9-11. (Pubitemid 47338623)
3. Butler M. Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals. Appl Microbiol Biotechnol 2005; 68:283-291 (Pubitemid 41159998)
4. th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production, Bioplan Associates, Inc 2008.
5. Source: US Federal Reserve Statistical Release, Industrial Production Capacity and Utilization 2008.
6. Source: US Federal Reserve Statistical Release, Industrial Production Capacity and Utilization, November 17 2008, http://www.federalreserve.gov/ releases/G17/Current/ (accessed 2008).
7. Ranshoff T. According to industry data, by 2005, the biopharmaceutical contract manufacturing industry had grown to an estimated $1.5 billion. CMOs now hold between 15-29% of the industry-wide capacity for both mammalian cell culture and microbial fermentation. BioPharm International 2007.
8. Morin N, Stevens J. Diverging Measures of Capacity Utilization: An Explanation, Divisions of Research & Statistics and Monetary Affairs, Federal Reserve Board, Washington DC 2004. http://www.federalreserve.gov/pubs/ feds/2004/200458/200458pap.pdf (accessed 2009).